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Alberto Mantovani
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Journal Articles

Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non–Small Cell Lung Cancer

Open Access
Alessandra Rigamonti, Marika Viatore, Rebecca Polidori, Daoud Rahal, Marco Erreni, Maria Rita Fumagalli, Damiano Zanini, Andrea Doni, Anna Rita Putignano, Paola Bossi, Emanuele Voulaz, Marco Alloisio, Sabrina Rossi, Paolo Andrea Zucali, Armando Santoro, Vittoria Balzano, Paola Nisticò, Friedrich Feuerhake, Alberto Mantovani, Massimo Locati, Federica Marchesi
Journal: Cancer Research
Cancer Res (2024) 84 (7): 1165–1177.
https://doi.org/10.1158/0008-5472.CAN-23-1698
Published: 01 April 2024
View article titled, Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non–Small Cell Lung Cancer
Open the PDF for Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 715: Nanomedicines loaded with TLR agonists and inhibitors of immunosuppression to reprogram the tumor microenvironment

Free
Fernando Torres Andon, Alba Pensado-López, Clement Anfray, Aldo Ummarino, Iago Fernández-Mariño, Lucia Sanjurjo, Jose Crecente-Campo, Eduardo Fernández-Megía, Flavia Castro, Maria Jose Oliveira, Alfonso Calvo, Rosario García Campelo, Alberto Mantovani, Maria Jose Alonso, Paola Allavena
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 715.
https://doi.org/10.1158/1538-7445.AM2024-715
Published: 22 March 2024
View article titled, Abstract 715: Nanomedicines loaded with TLR agonists and inhibitors of immunosuppression to reprogram the tumor microenvironment
Journal Articles

Abstract 5783: Integration of AI-powered digital pathology and imaging mass cytometry to identify relevant features of the tumor microenvironment

Free
Alessandra Rigamonti, Marika Viatore, Rebecca Polidori, Marco Erreni, Maria Fumagalli, Daoud Rahal, Massimo Locati, Alberto Mantovani, Federica Marchesi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5783.
https://doi.org/10.1158/1538-7445.AM2023-5783
Published: 04 April 2023
View article titled, Abstract 5783: Integration of AI-powered digital pathology and imaging mass cytometry to identify relevant features of the tumor microenvironment
Journal Articles

Abstract 5140: Combined administration of poly(I:C) and resiquimod triggers effective antitumoral response in mouse models of pancreatic adenocarcinoma

Free
Aldo Ummarino, Clément Anfray, Andrea Mariancini, Domenico Supino, Cecilia Garlanda, Fernando Torres Andòn, Alberto Mantovani, Paola Allavena
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5140.
https://doi.org/10.1158/1538-7445.AM2023-5140
Published: 04 April 2023
View article titled, Abstract 5140: Combined administration of poly(I:C) and resiquimod triggers effective antitumoral response in mouse models of pancreatic adenocarcinoma
Journal Articles

Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis

Free
Giulia Marelli, Marco Erreni, Achille Anselmo, Valentina Taverniti, Simone Guglielmetti, Alberto Mantovani, Paola Allavena
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4472–4485.
https://doi.org/10.1158/0008-5472.CAN-16-2501
Published: 14 August 2017
View article titled, Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis
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Includes: Supplementary data
Journal Articles

Abstract SY06-01: Tumor-associated myelomonocytic cells as therapeutic targets

Free
Maria R. Galdiero, Martina Molgora, Cecila Garlanda, Gianni Marone, Alberto Mantovani
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): SY06-01.
https://doi.org/10.1158/1538-7445.AM2017-SY06-01
Published: 01 July 2017
View article titled, Abstract SY06-01: Tumor-associated myelomonocytic cells as therapeutic targets
Journal Articles

Abstract A32: Colorectal cancer stroma: Tumor cells in disguise

Free
Giuseppe Celesti, Giuseppe Di Caro, Paolo Bianchi, Fabio Grizzi, Gianluca Basso, Andrea Doni, Federica Marchesi, Giancarlo Marra, Massimo Roncalli, Alberto Mantovani, Alberto Malesci, Luigi Laghi
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): A32.
https://doi.org/10.1158/1538-7445.TIM2013-A32
Published: 01 May 2014
View article titled, Abstract A32: Colorectal cancer stroma: Tumor cells in disguise
Journal Articles

Abstract 800: Inflammatory chemokines mediate immune surveillance of intestinal cancer

Free
Venkatakrishna R. Jala, Steven P. Mathis, Sobha R. Bodduluri, Paramahamsa Maturu, Elangovan Krishnan, Michelle E. Smith, Paula M. Chilton, Thomas C. Mitchell, Massimo Locati, Alberto Mantovani, Haribabu Bodduluri
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 800.
https://doi.org/10.1158/1538-7445.AM2011-800
Published: 15 April 2011
View article titled, Abstract 800: Inflammatory chemokines mediate immune surveillance of intestinal cancer
Journal Articles

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

Free
Giovanni Germano, Roberta Frapolli, Matteo Simone, Michele Tavecchio, Eugenio Erba, Samantha Pesce, Fabio Pasqualini, Federica Grosso, Roberta Sanfilippo, Paolo G. Casali, Alessandro Gronchi, Emanuela Virdis, Eva Tarantino, Silvana Pilotti, Angela Greco, Manuela Nebuloni, Carlos Maria Galmarini, Juan Carlos Tercero, Alberto Mantovani, Maurizio D'Incalci, Paola Allavena
Journal: Cancer Research
Cancer Res (2010) 70 (6): 2235–2244.
https://doi.org/10.1158/0008-5472.CAN-09-2335
Published: 14 March 2010
View article titled, Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells
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Includes: Supplementary data
Journal Articles

Inactivation of Junctional Adhesion Molecule-A Enhances Antitumoral Immune Response by Promoting Dendritic Cell and T Lymphocyte Infiltration

Free
Masato Murakami, Chiara Francavilla, Ilaria Torselli, Monica Corada, Luigi Maddaluno, Antonio Sica, Gianluca Matteoli, Iliyan Dimitrov Iliev, Alberto Mantovani, Maria Rescigno, Ugo Cavallaro, Elisabetta Dejana
Journal: Cancer Research
Cancer Res (2010) 70 (5): 1759–1765.
https://doi.org/10.1158/0008-5472.CAN-09-1703
Published: 28 February 2010
View article titled, Inactivation of Junctional Adhesion Molecule-A Enhances Antitumoral Immune Response by Promoting Dendritic Cell and T Lymphocyte Infiltration
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Includes: Supplementary data
Journal Articles

The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma

Free
Federica Marchesi, Lorenzo Piemonti, Giuseppe Fedele, Annarita Destro, Massimo Roncalli, Luca Albarello, Claudio Doglioni, Achille Anselmo, Andrea Doni, Paolo Bianchi, Luigi Laghi, Alberto Malesci, Luigi Cervo, MariaLuisa Malosio, Michele Reni, Alessandro Zerbi, Valerio Di Carlo, Alberto Mantovani, Paola Allavena
Journal: Cancer Research
Cancer Res (2008) 68 (21): 9060–9069.
https://doi.org/10.1158/0008-5472.CAN-08-1810
Published: 30 October 2008
View article titled, The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Anti-inflammatory properties of the novel anti-tumor agent trabectedin: Reduction of ccl2, il-6 and pentraxin-3 by monocytes/macrophages and tumor cells

Free
Giovanni Germano, Eugenio Erba, Michele Tavecchio, Maurizio D'Incalci, Jose Jimeno, Paola Allavena, Alberto Mantovani
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1197.
Published: 01 May 2008
View article titled, Anti-inflammatory properties of the novel anti-tumor agent trabectedin: Reduction of ccl2, il-6 and pentraxin-3 by monocytes/macrophages and tumor cells
Journal Articles

Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family

Free
Cecilia Garlanda, Federica Riva, Tania Veliz, Nadia Polentarutti, Fabio Pasqualini, Enrico Radaelli, Marina Sironi, Manuela Nebuloni, Elisabetta Omodeo Zorini, Eugenio Scanziani, Alberto Mantovani
Journal: Cancer Research
Cancer Res (2007) 67 (13): 6017–6021.
https://doi.org/10.1158/0008-5472.CAN-07-0560
Published: 06 July 2007
View article titled, Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family
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Journal Articles

p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

Free
Alessandra Saccani, Tiziana Schioppa, Chiara Porta, Subhra K. Biswas, Manuela Nebuloni, Luca Vago, Barbara Bottazzi, Mario P. Colombo, Alberto Mantovani, Antonio Sica
Journal: Cancer Research
Cancer Res (2006) 66 (23): 11432–11440.
https://doi.org/10.1158/0008-5472.CAN-06-1867
Published: 04 December 2006
View article titled, p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance
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Journal Articles

Targeting Myelomonocytic Cells to Revert Inflammation-Dependent Cancer Promotion

Free
Mario P. Colombo, Alberto Mantovani
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9113–9116.
https://doi.org/10.1158/0008-5472.CAN-05-2714
Published: 17 October 2005
View article titled, Targeting Myelomonocytic Cells to Revert Inflammation-Dependent Cancer Promotion
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Journal Articles

Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4

Free
Federica Marchesi, Paolo Monti, Biagio Eugenio Leone, Alessandro Zerbi, Annunciata Vecchi, Lorenzo Piemonti, Alberto Mantovani, Paola Allavena
Journal: Cancer Research
Cancer Res (2004) 64 (22): 8420–8427.
https://doi.org/10.1158/0008-5472.CAN-04-1343
Published: 17 November 2004
View article titled, Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4
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Journal Articles

Interleukin 1 Receptor Antagonist Inhibits the Augmentation of Metastasis Induced by Interleukin 1 or Lipopolysaccharide in a Human Melanoma/Nude Mouse System

Free
Renato G. S. Chirivi, Angela Garofalo, Ines Martin Padura, Alberto Mantovani, Raffaella Giavazzi
Journal: Cancer Research
Cancer Res (1993) 53 (20): 5051–5054.
Published: 01 October 1993
View article titled, Interleukin 1 Receptor Antagonist Inhibits the Augmentation of Metastasis Induced by Interleukin 1 or Lipopolysaccharide in a Human Melanoma/Nude Mouse System
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Journal Articles

Endothelial Cell Migration and Invasiveness Are Induced by a Soluble Factor Produced by Murine Endothelioma Cells Transformed by Polyoma Virus Middle T Oncogene

Free
Giulia Taraboletti, Dorina Belotti, Elisabetta Dejana, Alberto Mantovani, Raffaella Giavazzi
Journal: Cancer Research
Cancer Res (1993) 53 (16): 3812–3816.
Published: 01 August 1993
View article titled, Endothelial Cell Migration and Invasiveness Are Induced by a Soluble Factor Produced by Murine Endothelioma Cells Transformed by Polyoma Virus Middle T Oncogene
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Journal Articles

Heterogeneity in Human Melanoma Cell Adhesion to Cytokine Activated Endothelial Cells Correlates with VLA-4 Expression

Free
Inès Martìn-Padura, Roberta Mortarini, Davide Lauri, Sergio Bernasconi, Francisco Sanchez-Madrid, Giorgio Parmiani, Alberto Mantovani, Andrea Anichini, Elisabetta Dejana
Journal: Cancer Research
Cancer Res (1991) 51 (8): 2239–2241.
Published: 01 April 1991
View article titled, Heterogeneity in Human Melanoma Cell Adhesion to Cytokine Activated Endothelial Cells Correlates with VLA-4 Expression
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Journal Articles

Interleukin 1-induced Augmentation of Experimental Metastases from a Human Melanoma in Nude Mice

Free
Raffaella Giavazzi, Angela Garofalo, Maria Rosa Bani, Mauro Abbate, Pietro Ghezzi, Diana Boraschi, Alberto Mantovani, Elisabetta Dejana
Journal: Cancer Research
Cancer Res (1990) 50 (15): 4771–4775.
Published: 01 August 1990
View article titled, Interleukin 1-induced Augmentation of Experimental Metastases from a Human Melanoma in Nude Mice
Open the PDF for Interleukin 1-induced Augmentation of Experimental Metastases from a Human Melanoma in Nude Mice in another window