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Alan J. Tackett
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Journal Articles

Abstract LB041: EZH2 and ATF6 sense metabolic stress to balance MHC class I antigen presentation in melanoma

Jacob L. Edmondson, Megan R. Reed, Lauren C. Morehead, Billie Heflin, Brian Koss, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB041.
https://doi.org/10.1158/1538-7445.AM2023-LB041
Published: 14 April 2023
View article titled, Abstract LB041: EZH2 and ATF6 sense metabolic stress to balance MHC class I antigen presentation in melanoma
Journal Articles

Abstract 6131: Harnessing resveratrol-mediated restoration of MHC-I in melanoma to enhance immunotherapy

Lauren C. Morehead, Brian S. Koss, Isabelle R. Miousse, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6131.
https://doi.org/10.1158/1538-7445.AM2022-6131
Published: 15 June 2022
View article titled, Abstract 6131: Harnessing resveratrol-mediated restoration of MHC-I in melanoma to enhance immunotherapy
Journal Articles

Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy

Santosh Kumar Paidi, Joel Rodriguez Troncoso, Piyush Raj, Paola Monterroso Diaz, Jesse D. Ivers, David E. Lee, Nathan L. Avaritt, Allen J. Gies, Charles M. Quick, Stephanie D. Byrum, Alan J. Tackett, Narasimhan Rajaram, Ishan Barman
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5745–5755.
https://doi.org/10.1158/0008-5472.CAN-21-1438
Published: 15 November 2021
View article titled, Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
Open the PDF for Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 1577: Caloric restriction mimetics as adjuvant to immune checkpoint inhibitors for treatment of melanoma

Lauren C. Morehead, Brian S. Koss, Katherine F. Wallis, Alan J. Tackett, Isabelle Racine Miousse
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1577.
https://doi.org/10.1158/1538-7445.AM2021-1577
Published: 01 July 2021
View article titled, Abstract 1577: Caloric restriction mimetics as adjuvant to immune checkpoint inhibitors for treatment of melanoma
Journal Articles

Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion

Brian Koss, Bradley D. Shields, Erin M. Taylor, Aaron J. Storey, Stephanie D. Byrum, Allen J. Gies, Charity L. Washam, Samrat Roy Choudhury, Jeong Hyun Ahn, Hidetaka Uryu, Jason B. Williams, Kimberly J. Krager, Tung-Chin Chiang, Samuel G. Mackintosh, Rick D. Edmondson, Nukhet Aykin-Burns, Thomas F. Gajewski, Gang Greg Wang, Alan J. Tackett
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (21): 4707–4719.
https://doi.org/10.1158/0008-5472.CAN-20-0524
Published: 03 November 2020
View article titled, Epigenetic Control of <em>Cdkn2a.Arf</em> Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion
Open the PDF for Epigenetic Control of <em>Cdkn2a.Arf</em> Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion in another window
Includes: Supplementary data
Journal Articles

Abstract A06: Differential response to autophagy in primary versus melanoma cells

Lauren C. Morehead, Alan J. Tackett, Isabelle R. Miousse
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): A06.
https://doi.org/10.1158/1538-7445.MEL2019-A06
Published: 02 October 2020
View article titled, Abstract A06: Differential response to autophagy in primary versus melanoma cells
Journal Articles

Abstract 1029: Epigenetic control of tumor-infiltrating lymphocyte metabolic-exhaustion

Brian Koss, Bradley D. Shields, Erin M. Taylor, Aaron J. Storey, Stephanie D. Byrum, Allen J. Gies, Charity L. Washam, Samrat Roy Choudhury, Jeong Hyun Ahn, Hidetaka Uryu, Kimberly J. Krager, Tung-Chin Chiang, Samuel G. Mackintosh, Rick D. Edmondson, Nukhet Aykin-Burns, Gang Greg Wang, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1029.
https://doi.org/10.1158/1538-7445.AM2020-1029
Published: 15 August 2020
View article titled, Abstract 1029: Epigenetic control of tumor-infiltrating lymphocyte metabolic-exhaustion
Journal Articles

Abstract LB-182: Combination of sulforaphane and 5-aza-2′-deoxycytidine slows the growth and upregulates the chemoattractant CCL5 in metastatic melanoma

Tung-Chin Chiang, Brian Koss, Aaron J. Storey, Jovanny Zabaleta, Samrat Roy Choudhury, Bradley D. Shields, Elizabeth C. Draper, L Joseph Su, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-182.
https://doi.org/10.1158/1538-7445.AM2020-LB-182
Published: 15 August 2020
View article titled, Abstract LB-182: Combination of sulforaphane and 5-aza-2′-deoxycytidine slows the growth and upregulates the chemoattractant CCL5 in metastatic melanoma
Journal Articles

Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma

Bradley D. Shields, Brian Koss, Erin M. Taylor, Aaron J. Storey, Kirk L. West, Stephanie D. Byrum, Samuel G. Mackintosh, Rick Edmondson, Fade Mahmoud, Sara C. Shalin, Alan J. Tackett
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (6): 1113–1123.
https://doi.org/10.1158/0008-5472.CAN-18-1722
Published: 15 March 2019
View article titled, Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
Open the PDF for Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2037: E-cadherin enhances immune control of metastatic melanoma

Bradley D. Shields, Brian Koss, Fade Mahmoud, Stephanie D. Byrum, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2037.
https://doi.org/10.1158/1538-7445.AM2018-2037
Published: 01 July 2018
View article titled, Abstract 2037: E-cadherin enhances immune control of metastatic melanoma
Journal Articles

Abstract LB-206: Indicators of responsiveness to immune checkpoint inhibitors

Bradley D. Shields, Fade Mahmoud, Erin M. Taylor, Stephanie D. Byrum, Deepanwita Sengupta, Brian Koss, Giulia Baldini, Seth Ransom, Kyle Cline, Samuel Mackintosh, Ricky Edmondson, Sara C. Shalin, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-206.
https://doi.org/10.1158/1538-7445.AM2017-LB-206
Published: 01 July 2017
View article titled, Abstract LB-206: Indicators of responsiveness to immune checkpoint inhibitors
Journal Articles

Abstract 1146: Enhancer of zeste homolog 2 (EZH2) inhibition in metastatic melanoma promotes tumor regression in vivo

Deepanwita Sengupta, Nathan Avaritt, Sara C. Shalin, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1146.
https://doi.org/10.1158/1538-7445.AM2016-1146
Published: 15 July 2016
View article titled, Abstract 1146: Enhancer of zeste homolog 2 (EZH2) inhibition in metastatic melanoma promotes tumor regression <em>in vivo</em>
Journal Articles

Abstract B15: Combination chemotherapy in melanoma using EZH2 inhibitor

Deepanwita Sengupta, Nathan L. Avaritt, Alan J. Tackett
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): B15.
https://doi.org/10.1158/1538-7445.MEL2014-B15
Published: 16 July 2015
View article titled, Abstract B15: Combination chemotherapy in melanoma using EZH2 inhibitor