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Alan Hewer
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Journal Articles

Human Enzymes Involved in the Metabolic Activation of the Environmental Contaminant 3-Nitrobenzanthrone: Evidence for Reductive Activation by Human NADPH:Cytochrome P450 Reductase

Free
Volker M. Arlt, Marie Stiborova, Alan Hewer, Heinz H. Schmeiser, David H. Phillips
Journal: Cancer Research
Cancer Res (2003) 63 (11): 2752–2761.
Published: 01 June 2003
View articletitled, Human Enzymes Involved in the Metabolic Activation of the Environmental Contaminant 3-Nitrobenzanthrone: Evidence for Reductive Activation by Human NADPH:Cytochrome P450 Reductase
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Includes: Supplementary data
Journal Articles

Mutability of p53 Hotspot Codons to Benzo(a)pyrene Diol Epoxide (BPDE) and the Frequency of p53 Mutations in Nontumorous Human Lung

Free
S. Perwez Hussain, Paul Amstad, Kamran Raja, Mark Sawyer, Lorne Hofseth, Peter G. Shields, Alan Hewer, David H. Phillips, David Ryberg, Aage Haugen, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2001) 61 (17): 6350–6355.
Published: 01 September 2001
View articletitled, Mutability of p53 Hotspot Codons to Benzo(a)pyrene Diol Epoxide (BPDE) and the Frequency of p53 Mutations in Nontumorous Human Lung
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Journal Articles

Sex Differences in the Activation of Tamoxifen to DNA Binding Species in Rat Liver in Vivo and in Rat Hepatocytes in Vitro: Role of Sulfotransferase Induction

Free
Warren Davis, Alan Hewer, Krzysztof M. Rajkowski, Walter Meinl, Hansruedi Glatt, David H. Phillips
Journal: Cancer Research
Cancer Res (2000) 60 (11): 2887–2891.
Published: 01 June 2000
View articletitled, Sex Differences in the Activation of Tamoxifen to DNA Binding Species in Rat Liver in Vivo and in Rat Hepatocytes in Vitro: Role of Sulfotransferase Induction
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Journal Articles

Tamoxifen-DNA Adduct Formation in Rat Liver Determined by Immunoassay and 32P-Postlabeling

Free
Rao L. Divi, Martin R. Osborne, Alan Hewer, David H. Phillips, Miriam C. Poirier
Journal: Cancer Research
Cancer Res (1999) 59 (19): 4829–4833.
Published: 01 October 1999
View articletitled, Tamoxifen-DNA Adduct Formation in Rat Liver Determined by Immunoassay and 32P-Postlabeling
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Journal Articles

Identification of the Major Tamoxifen-Deoxyguanosine Adduct Formed in the Liver DNA of Rats Treated with Tamoxifen

Free
Martin R. Osborne, Alan Hewer, Ian R. Hardcastle, Paul L. Carmichael, David H. Phillips
Journal: Cancer Research
Cancer Res (1996) 56 (1): 66–71.
Published: 01 January 1996
View articletitled, Identification of the Major Tamoxifen-Deoxyguanosine Adduct Formed in the Liver DNA of Rats Treated with Tamoxifen
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Journal Articles

Different Susceptibility to Smoking-induced DNA Damage among Male and Female Lung Cancer Patients

Free
David Ryberg, Alan Hewer, David H. Phillips, Aage Haugen
Journal: Cancer Research
Cancer Res (1994) 54 (22): 5801–5803.
Published: 01 November 1994
View articletitled, Different Susceptibility to Smoking-induced DNA Damage among Male and Female Lung Cancer Patients
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Journal Articles

α-Hydroxytamoxifen, a Metabolite of Tamoxifen with Exceptionally High DNA-binding Activity in Rat Hepatocytes

Free
David H. Phillips, Paul L. Carmichael, Alan Hewer, Kathleen J. Cole, Grace K. Poon
Journal: Cancer Research
Cancer Res (1994) 54 (21): 5518–5522.
Published: 01 November 1994
View articletitled, α-Hydroxytamoxifen, a Metabolite of Tamoxifen with Exceptionally High DNA-binding Activity in Rat Hepatocytes
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Journal Articles

Detection of Polycyclic Aromatic Hydrocarbon-DNA Adducts in White Blood Cells from Coke Oven Workers: Correlation with Job Categories

Free
Steinar Øvrebø, Aage Haugen, David H. Phillips, Alan Hewer
Journal: Cancer Research
Cancer Res (1992) 52 (6): 1510–1514.
Published: 01 March 1992
View articletitled, Detection of Polycyclic Aromatic Hydrocarbon-DNA Adducts in White Blood Cells from Coke Oven Workers: Correlation with Job Categories
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Journal Articles

Influence of the Alkyl Substituent on Mutagenicity and Covalent DNA Binding of Bay Region Diol-Epoxides of 7-Methyl- and 7-Ethylbenz(a)anthracene in Salmonella and V79 Chinese Hamster Cells

Free
Hansruedi Glatt, Ronald G. Harvey, David H. Phillips, Alan Hewer, Philip L. Grover
Journal: Cancer Research
Cancer Res (1989) 49 (7): 1778–1782.
Published: 01 April 1989
View articletitled, Influence of the Alkyl Substituent on Mutagenicity and Covalent DNA Binding of Bay Region Diol-Epoxides of 7-Methyl- and 7-Ethylbenz(a)anthracene in Salmonella and V79 Chinese Hamster Cells
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Journal Articles

Aberrant Activation of Benzo(a)pyrene in Cultured Rat Mammary Cells in Vitro and following Direct Application to Rat Mammary Glands in Vivo

Free
David H. Phillips, Alan Hewer, Philip L. Grover
Journal: Cancer Research
Cancer Res (1985) 45 (9): 4167–4174.
Published: 01 September 1985
View articletitled, Aberrant Activation of Benzo(a)pyrene in Cultured Rat Mammary Cells in Vitro and following Direct Application to Rat Mammary Glands in Vivo
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