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Journal Articles

Abstract CT139: Immunological activity of oncolytic adenovirus encoding TNFα and IL-2 (TILT-123) in combination with pembrolizumab in platinum resistant or refractory ovarian cancer patients

Cancer Res (2024) 84 (7_Supplement): CT139.

https://doi.org/10.1158/1538-7445.AM2024-CT139

Published: 05 April 2024

View article titled, Abstract CT139: Immunological activity of oncolytic adenovirus encoding TNFα and IL-2 (TILT-123) in combination with pembrolizumab in platinum resistant or refractory ovarian cancer patients

Journal Articles

Abstract 3643: Tumor-specific oncolytic adenovirus coding for trastuzumab results in local production of functional monoclonal antibody from tumor cells

Ilkka Liikanen, Paula Savola, Akseli Hemminki

Cancer Res (2014) 74 (19_Supplement): 3643.

https://doi.org/10.1158/1538-7445.AM2014-3643

Published: 01 October 2014

View article titled, Abstract 3643: Tumor-specific oncolytic adenovirus coding for trastuzumab results in local production of functional monoclonal antibody from tumor cells

Journal Articles

Abstract 2587: Dasatinib-induced reduction of tumor growth is accompanied by the changes in the immune profile in melanoma B16.OVA mouse model

Can Hekim, Mette Ilander, Markus Vähä-Koskela, Paula Savola, Siri Tähtinen, Akseli Hemminki, Kimmo Porkka, Satu Mustjoki

Cancer Res (2014) 74 (19_Supplement): 2587.

https://doi.org/10.1158/1538-7445.AM2014-2587

Published: 01 October 2014

View article titled, Abstract 2587: Dasatinib-induced reduction of tumor growth is accompanied by the changes in the immune profile in melanoma B16.OVA mouse model

Journal Articles

Abstract 3304: Oncolytic adenovirus with low-dose temozolomide induces autophagy and antitumor immune responses preclinically and in cancer patients.

Ilkka Liikanen, Laura Ahtiainen, Mari L.M Hirvinen, Simona Barmante, Vincenzo Cerullo, Petri Nokisalmi, Otto Hemminki, Iulia Diaconu, Sari Pesonen, Anniina Koski, Lotta Kangasniemi, Saila K. Pesonen, Minna Oksanen, Fang Zhao, Leena Laasonen, Kaarina Partanen, Timo Joensuu, Anna Kanerva, Akseli Hemminki

Cancer Res (2013) 73 (8_Supplement): 3304.

https://doi.org/10.1158/1538-7445.AM2013-3304

Published: 15 April 2013

View article titled, Abstract 3304: Oncolytic adenovirus with low-dose temozolomide induces autophagy and antitumor immune responses preclinically and in cancer patients.

Journal Articles

Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

Iulia Diaconu, Vincenzo Cerullo, Mari L.M. Hirvinen, Sophie Escutenaire, Matteo Ugolini, Saila K. Pesonen, Simona Bramante, Suvi Parviainen, Anna Kanerva, Angelica S.I. Loskog, Aristides G. Eliopoulos, Sari Pesonen, Akseli Hemminki

Cancer Res (2012) 72 (9): 2327–2338.

https://doi.org/10.1158/0008-5472.CAN-11-2975

Published: 30 April 2012

View article titled, Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

Includes: Supplementary data

Journal Articles

Oncolytic Immunotherapy of Advanced Solid Tumors with a CD40L-Expressing Replicating Adenovirus: Assessment of Safety and Immunologic Responses in Patients

Cancer Res (2012) 72 (7): 1621–1631.

https://doi.org/10.1158/0008-5472.CAN-11-3001

Published: 01 April 2012

View article titled, Oncolytic Immunotherapy of Advanced Solid Tumors with a CD40L-Expressing Replicating Adenovirus: Assessment of Safety and Immunologic Responses in Patients

Includes: Supplementary data

Journal Articles

Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients

Cancer Res (2010) 70 (11): 4297–4309.

https://doi.org/10.1158/0008-5472.CAN-09-3567

Published: 01 June 2010

View article titled, Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients

Includes: Supplementary data

Journal Articles

Epithelial Phenotype Confers Resistance of Ovarian Cancer Cells to Oncolytic Adenoviruses

Robert Strauss, Pavel Sova, Ying Liu, Zong Yi Li, Sebastian Tuve, David Pritchard, Paul Brinkkoetter, Thomas Möller, Oliver Wildner, Sari Pesonen, Akseli Hemminki, Nicole Urban, Charles Drescher, André Lieber

Cancer Res (2009) 69 (12): 5115–5125.

https://doi.org/10.1158/0008-5472.CAN-09-0645

Published: 15 June 2009

View article titled, Epithelial Phenotype Confers Resistance of Ovarian Cancer Cells to Oncolytic Adenoviruses

Includes: Supplementary data

Journal Articles

Tissue-Specific Promoters Active in CD44⁺CD24^−/low Breast Cancer Cells

Gerd J. Bauerschmitz, Tuuli Ranki, Lotta Kangasniemi, Camilla Ribacka, Minna Eriksson, Marius Porten, Isabell Herrmann, Ari Ristimäki, Pekka Virkkunen, Maija Tarkkanen, Tanja Hakkarainen, Anna Kanerva, Daniel Rein, Sari Pesonen, Akseli Hemminki

Cancer Res (2008) 68 (14): 5533–5539.

https://doi.org/10.1158/0008-5472.CAN-07-5288

Published: 15 July 2008

View article titled, Tissue-Specific Promoters Active in CD44+CD24−/low Breast Cancer Cells

Journal Articles

Treatment of cancer patients with capsid modified double controlled oncolytic adenovirus Ad5/3-Cox2L-D24

Sari Pesonen, Petri Nokisalmi, Ari Ristimaki, Teemu Kantola, Gerd Bauerschmitz, Anna Kanerva, Timo Joensuu, Akseli Hemminki

Cancer Res (2008) 68 (9_Supplement): 2818.

Published: 01 May 2008

View article titled, Treatment of cancer patients with capsid modified double controlled oncolytic adenovirus Ad5/3-Cox2L-D24

Journal Articles

Combination of suicide gene therapy with an RGD-modified virus and chemotherapy.

Isabell Herrmann, Gernot Roeder, Gerd J. Bauerschmitz, Akseli Hemminki, David T. Curiel, Dieter Niederacher, Peter Dall

Cancer Res (2004) 64 (7_Supplement): 871–872.

Published: 01 April 2004

View article titled, Combination of suicide gene therapy with an RGD-modified virus and chemotherapy.

Journal Articles

Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral Transgene Expression

Akseli Hemminki, Anna Kanerva, Bin Liu, Minghui Wang, Ronald D. Alvarez, Gene P. Siegal, David T. Curiel

Cancer Res (2003) 63 (4): 847–853.

Published: 15 February 2003

View article titled, Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral Transgene Expression

Journal Articles

Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors

Yosef S. Haviv, Jerry L. Blackwell, Anna Kanerva, Peter Nagi, Victor Krasnykh, Igor Dmitriev, Minghui Wang, Seiji Naito, Xiaosheng Lei, Akseli Hemminki, Delicia Carey, David T. Curiel

Cancer Res (2002) 62 (15): 4273–4281.

Published: 01 August 2002

View article titled, Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors

Journal Articles

The flt-1 Promoter for Transcriptional Targeting of Teratocarcinoma

Gerd J. Bauerschmitz, Dirk M. Nettelbeck, Anna Kanerva, Andrew H. Baker, Akseli Hemminki, Paul N. Reynolds, David T. Curiel

Cancer Res (2002) 62 (5): 1271–1274.

Published: 01 March 2002

View article titled, The flt-1 Promoter for Transcriptional Targeting of Teratocarcinoma

Journal Articles

Treatment of Ovarian Cancer with a Tropism Modified Oncolytic Adenovirus

Gerd J. Bauerschmitz, John T. Lam, Anna Kanerva, Kaori Suzuki, Dirk M. Nettelbeck, Igor Dmitriev, Victor Krasnykh, Galina V. Mikheeva, Mack N. Barnes, Ronald D. Alvarez, Peter Dall, Ramon Alemany, David T. Curiel, Akseli Hemminki

Cancer Res (2002) 62 (5): 1266–1270.

Published: 01 March 2002

View article titled, Treatment of Ovarian Cancer with a Tropism Modified Oncolytic Adenovirus

Journal Articles

Targeting Oncolytic Adenoviral Agents to the Epidermal Growth Factor Pathway with a Secretory Fusion Molecule

Akseli Hemminki, Igor Dmitriev, Bin Liu, Renee A. Desmond, Ramon Alemany, David T. Curiel

Cancer Res (2001) 61 (17): 6377–6381.

Published: 01 September 2001

View article titled, Targeting Oncolytic Adenoviral Agents to the Epidermal Growth Factor Pathway with a Secretory Fusion Molecule

Journal Articles

Somatic Mutations in LKB1 Are Rare in Sporadic Colorectal and Testicular Tumors

Egle Avizienyte, Stina Roth, Anu Loukola, Akseli Hemminki, Ragnhild A. Lothe, Anna E. Stenwig, Sophie D. Fosså, Reijo Salovaara, Lauri A. Aaltonen

Cancer Res (1998) 58 (10): 2087–2090.

Published: 01 May 1998

View article titled, Somatic Mutations in LKB1 Are Rare in Sporadic Colorectal and Testicular Tumors

Journal Articles

Exclusion of PTEN and 10q22–24 As the Susceptibility Locus for Juvenile Polyposis Syndrome

Cancer Res (1997) 57 (22): 5017–5021.

Published: 01 November 1997

View article titled, Exclusion of PTEN and 10q22–24 As the Susceptibility Locus for Juvenile Polyposis Syndrome

Journal Articles

Semiautomated Assessment of Loss of Heterozygosity and Replication Error in Tumors

Federico Canzian, Reijo Salovaara, Akseli Hemminki, Paula Kristo, Robert B. Chadwick, Lauri A. Aaltonen, Albert de la Chapelle

Cancer Res (1996) 56 (14): 3331–3337.

Published: 01 July 1996

View article titled, Semiautomated Assessment of Loss of Heterozygosity and Replication Error in Tumors

NARROW

Abstract CT139: Immunological activity of oncolytic adenovirus encoding TNFα and IL-2 (TILT-123) in combination with pembrolizumab in platinum resistant or refractory ovarian cancer patients

Abstract 3643: Tumor-specific oncolytic adenovirus coding for trastuzumab results in local production of functional monoclonal antibody from tumor cells

Abstract 2587: Dasatinib-induced reduction of tumor growth is accompanied by the changes in the immune profile in melanoma B16.OVA mouse model

Abstract 3304: Oncolytic adenovirus with low-dose temozolomide induces autophagy and antitumor immune responses preclinically and in cancer patients.

Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

Oncolytic Immunotherapy of Advanced Solid Tumors with a CD40L-Expressing Replicating Adenovirus: Assessment of Safety and Immunologic Responses in Patients

Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients

Epithelial Phenotype Confers Resistance of Ovarian Cancer Cells to Oncolytic Adenoviruses

Tissue-Specific Promoters Active in CD44⁺CD24^−/low Breast Cancer Cells

Treatment of cancer patients with capsid modified double controlled oncolytic adenovirus Ad5/3-Cox2L-D24

Combination of suicide gene therapy with an RGD-modified virus and chemotherapy.

Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral Transgene Expression

Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors

The flt-1 Promoter for Transcriptional Targeting of Teratocarcinoma

Treatment of Ovarian Cancer with a Tropism Modified Oncolytic Adenovirus

Targeting Oncolytic Adenoviral Agents to the Epidermal Growth Factor Pathway with a Secretory Fusion Molecule

Somatic Mutations in LKB1 Are Rare in Sporadic Colorectal and Testicular Tumors

Exclusion of PTEN and 10q22–24 As the Susceptibility Locus for Juvenile Polyposis Syndrome

Semiautomated Assessment of Loss of Heterozygosity and Replication Error in Tumors

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