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Abstract 821: DNA hypermethylation of IRX4 is a frequent event that may confer growth advantage to pancreatic cancer cells

Kanchan Chakma, Zhaodi Gu, Fuyuhiko Motoi, Michiaki Unno, Akira Horii, Shinichi Fukushige

Cancer Res (2019) 79 (13_Supplement): 821.

https://doi.org/10.1158/1538-7445.AM2019-821

Published: 01 July 2019

View articletitled, Abstract 821: DNA hypermethylation of IRX4 is a frequent event that may confer growth advantage to pancreatic cancer cells

Journal Articles

Abstract 4354: Methylation-mediated silenced PYCARD plays a key role in human prostate cancer

Shinichi Fukushige, Toshiya Miyauchi, Teppei Okubo, Koji Mitsuzuka, Yoichi Arai, Akira Horii

Cancer Res (2017) 77 (13_Supplement): 4354.

https://doi.org/10.1158/1538-7445.AM2017-4354

Published: 01 July 2017

View articletitled, Abstract 4354: Methylation-mediated silenced PYCARD plays a key role in human prostate cancer

Journal Articles

Abstract 4432: Targeted TET oxidase activity through methyl-CpG binding domain extensively suppresses cancer cell proliferation

Shinichi Fukushige, Yasuhiko Mizuguchi, Kanchan Chakma, Yuriko Saiki, Akira Horii

Cancer Res (2016) 76 (14_Supplement): 4432.

https://doi.org/10.1158/1538-7445.AM2016-4432

Published: 15 July 2016

View articletitled, Abstract 4432: Targeted TET oxidase activity through methyl-CpG binding domain extensively suppresses cancer cell proliferation

Journal Articles

Abstract 5473: Human cancer cells acquire chemoresistance to gemcitabine mainly through loss-of-function mutations in the DCK gene

Akira Horii, Yuriko Saiki, Tomohiro Nakano, Chiharu Kudo, Makoto Sunamura

Cancer Res (2015) 75 (15_Supplement): 5473.

https://doi.org/10.1158/1538-7445.AM2015-5473

Published: 01 August 2015

View articletitled, Abstract 5473: Human cancer cells acquire chemoresistance to gemcitabine mainly through loss-of-function mutations in the DCK gene

Journal Articles

Abstract 396: TET oxidase activity accumulated on methyl-CpG sites extensively upregulates methylated genes through DNA demethylation

Shinichi Fukushige, Yasuhiko Mizuguchi, Akira Horii

Cancer Res (2014) 74 (19_Supplement): 396.

https://doi.org/10.1158/1538-7445.AM2014-396

Published: 01 October 2014

View articletitled, Abstract 396: TET oxidase activity accumulated on methyl-CpG sites extensively upregulates methylated genes through DNA demethylation

Journal Articles

Abstract 4993: IFI27 and NOV, downstream regulated genes by S100A4, are playing important roles in pancreatic carcinogenesis

Na Chen, Yuriko Saiki, Hitoshi Sekine, Makoto Sunamura, Shinichi Fukushige, Fuyuhiko Motoi, Shinichi Egawa, Michiaki Unno, Akira Horii

Cancer Res (2014) 74 (19_Supplement): 4993.

https://doi.org/10.1158/1538-7445.AM2014-4993

Published: 01 October 2014

View articletitled, Abstract 4993: IFI27 and NOV, downstream regulated genes by S100A4, are playing important roles in pancreatic carcinogenesis

Journal Articles

Abstract 4233: MeTA-array, a useful method to identify genes transcriptionally silenced by tumor-specific hypermethylation in cancer.

Shinichi Fukushige, Akira Horii

Cancer Res (2013) 73 (8_Supplement): 4233.

https://doi.org/10.1158/1538-7445.AM2013-4233

Published: 15 April 2013

View articletitled, Abstract 4233: MeTA-array, a useful method to identify genes transcriptionally silenced by tumor-specific hypermethylation in cancer.

Journal Articles

Abstract 179: Identification of novel targets for aberrant methylation in pancreatic cancer by a newly developed method “methyl-CpG targeted transcriptional activation (MeTA)”

Shinichi Fukushige, Hideyuki Shimizu, Yuko Sato, Akira Horii

Cancer Res (2010) 70 (8_Supplement): 179.

https://doi.org/10.1158/1538-7445.AM10-179

Published: 15 April 2010

View articletitled, Abstract 179: Identification of novel targets for aberrant methylation in pancreatic cancer by a newly developed method “methyl-CpG targeted transcriptional activation (MeTA)”

Journal Articles

Abstract 5295: S100A4 regulates tumor growth, motility, and invasion in pancreatic cancer

Hitoshi Sekine, Takahiro Tabata, Nobukazu Tsukamoto, Akihiro Yamamura, Keiko Abe, Yuki Yoshino, Keisuke Sato, Na Chen, Yukiko Umetsu, Daisuke Sato, Zhaodi Gu, Shinichi Fukushige, Kentaro Shima, Fuyuhiko Motoi, Shinichi Egawa, Makoto Sunamura, Akira Horii

Cancer Res (2010) 70 (8_Supplement): 5295.

https://doi.org/10.1158/1538-7445.AM10-5295

Published: 15 April 2010

View articletitled, Abstract 5295: S100A4 regulates tumor growth, motility, and invasion in pancreatic cancer

Journal Articles

Abstract 4933: Expression of the N-myc downstream-regulated gene 2 (NDRG2) is frequently suppressed by promoter hypermethylation in human gastrointestinal and pancreatic cancers

Akihiro Yamamura, Koh Miura, Hideaki Karasawa, Keiko Abe, Yasuhiko Mizuguchi, Guo Jin, Zhaodi Gu, Shinichi Fukushige, Naoyuki Kaneko, Makoto Kinouchi, Toshinori Ando, Nobuki Yazaki, Naoki Tanaka, Tomohiko Sase, Chikashi Shibata, Iwao Sasaki, Akira Horii

Cancer Res (2010) 70 (8_Supplement): 4933.

https://doi.org/10.1158/1538-7445.AM10-4933

Published: 15 April 2010

View articletitled, Abstract 4933: Expression of the N-myc downstream-regulated gene 2 (NDRG2) is frequently suppressed by promoter hypermethylation in human gastrointestinal and pancreatic cancers

Journal Articles

Abstract #1535: Transcriptional regulation of DUSP6 in a feedback loop manner responding to MAPK1 via ETS2 in human cells

Toru Furukawa, Etsuko Tanji, Shanhai Xu, Akira Horii

Cancer Res (2009) 69 (9_Supplement): 1535.

Published: 01 May 2009

View articletitled, Abstract #1535: Transcriptional regulation of DUSP6 in a feedback loop manner responding to MAPK1 via ETS2 in human cells

Journal Articles

Abstract #2740: The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma

Zhaodi Gu, Hidetoshi Mitsui, Susumu Morosawa, Akira Sakurada, Masami Sato, Takashi Kondo, Akira Horii

Cancer Res (2009) 69 (9_Supplement): 2740.

Published: 01 May 2009

View articletitled, Abstract #2740: The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma

Journal Articles

Elucidation of S100A4, one of the strong candidates for molecular target therapy in pancreatic cancer

Zhaodi Gu, Nobukazu Tsukamoto, Daisuke Sato, Takahiro Tabata, Akira Horii

Cancer Res (2008) 68 (9_Supplement): 109.

Published: 01 May 2008

View articletitled, Elucidation of S100A4, one of the strong candidates for molecular target therapy in pancreatic cancer

Journal Articles

Suppressed expression of FBXW7 and contrastive enhanced expressions of positive cell cycle regulators in human glioma

Zhaodi Gu, Kenichi Inomata, Hidetoshi Mitsui, Akira Horii

Cancer Res (2007) 67 (9_Supplement): 5188.

Published: 01 May 2007

View articletitled, Suppressed expression of FBXW7 and contrastive enhanced expressions of positive cell cycle regulators in human glioma

Journal Articles

Knockdown of S100A4 causes suppression of cell growth and motility in pancreatic cancer cells

Takahiro Tabata, Daisuke Sato, Shinichiro Sunamura, Toru Furukawa, Masaharu Ishida, Makoto Sunamura, Akira Horii

Cancer Res (2007) 67 (9_Supplement): 4859.

Published: 01 May 2007

View articletitled, Knockdown of S100A4 causes suppression of cell growth and motility in pancreatic cancer cells

Journal Articles

Elevated Expression of Mitogen-Activated Protein Kinase Phosphatase 3 in Breast Tumors: A Mechanism of Tamoxifen Resistance

Yukun Cui, Irma Parra, Mao Zhang, Susan G. Hilsenbeck, Anna Tsimelzon, Toru Furukawa, Akira Horii, Zhong-Yin Zhang, Robert I. Nicholson, Suzanne A.W. Fuqua

Cancer Res (2006) 66 (11): 5950–5959.

https://doi.org/10.1158/0008-5472.CAN-05-3243

Published: 01 June 2006

View articletitled, Elevated Expression of Mitogen-Activated Protein Kinase Phosphatase 3 in Breast Tumors: A Mechanism of Tamoxifen Resistance

Journal Articles

Ret finger protein mediates MBD2- and MBD4-dependent transcriptional repression

Shinichi Fukushige, Zhaodi Gu, Emiko Kondo, Akira Horii

Cancer Res (2006) 66 (8_Supplement): 5.

Published: 15 April 2006

View articletitled, Ret finger protein mediates MBD2- and MBD4-dependent transcriptional repression

Journal Articles

Search for tumor suppressor genes on chromosome 18 in pancreatic cancer

Masaharu Ishida, Makoto Sunamura, Shinichi Egawa, Toru Furukawa, Akira Horii, Michiaki Unno

Cancer Res (2006) 66 (8_Supplement): 197.

Published: 15 April 2006

View articletitled, Search for tumor suppressor genes on chromosome 18 in pancreatic cancer

Journal Articles

AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

Toru Furukawa, Akira Horii

Cancer Res (2006) 66 (8_Supplement): 1003–1004.

Published: 15 April 2006

View articletitled, AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

Journal Articles

Elucidation of downstream targets of MAPK1/ERK2 in pancreatic cancer.

Toru Furukawa, Naomi Kanai, Akira Horii

Cancer Res (2005) 65 (9_Supplement): 16.

Published: 01 May 2005

View articletitled, Elucidation of downstream targets of MAPK1/ERK2 in pancreatic cancer.

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Abstract 821: DNA hypermethylation of IRX4 is a frequent event that may confer growth advantage to pancreatic cancer cells

Abstract 4354: Methylation-mediated silenced PYCARD plays a key role in human prostate cancer

Abstract 4432: Targeted TET oxidase activity through methyl-CpG binding domain extensively suppresses cancer cell proliferation

Abstract 5473: Human cancer cells acquire chemoresistance to gemcitabine mainly through loss-of-function mutations in the DCK gene

Abstract 396: TET oxidase activity accumulated on methyl-CpG sites extensively upregulates methylated genes through DNA demethylation

Abstract 4993: IFI27 and NOV, downstream regulated genes by S100A4, are playing important roles in pancreatic carcinogenesis

Abstract 4233: MeTA-array, a useful method to identify genes transcriptionally silenced by tumor-specific hypermethylation in cancer.

Abstract 179: Identification of novel targets for aberrant methylation in pancreatic cancer by a newly developed method “methyl-CpG targeted transcriptional activation (MeTA)”

Abstract 5295: S100A4 regulates tumor growth, motility, and invasion in pancreatic cancer

Abstract 4933: Expression of the N-myc downstream-regulated gene 2 (NDRG2) is frequently suppressed by promoter hypermethylation in human gastrointestinal and pancreatic cancers

Abstract #1535: Transcriptional regulation of DUSP6 in a feedback loop manner responding to MAPK1 via ETS2 in human cells

Abstract #2740: The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma

Elucidation of S100A4, one of the strong candidates for molecular target therapy in pancreatic cancer

Suppressed expression of FBXW7 and contrastive enhanced expressions of positive cell cycle regulators in human glioma

Knockdown of S100A4 causes suppression of cell growth and motility in pancreatic cancer cells

Elevated Expression of Mitogen-Activated Protein Kinase Phosphatase 3 in Breast Tumors: A Mechanism of Tamoxifen Resistance

Ret finger protein mediates MBD2- and MBD4-dependent transcriptional repression

Search for tumor suppressor genes on chromosome 18 in pancreatic cancer

AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

Elucidation of downstream targets of MAPK1/ERK2 in pancreatic cancer.

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