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Journal Articles

Abstract CT004: KEYLYNK-007: Tumor agnostic trial of olaparib plus pembrolizumab in homologous recombination repair mutation- and homologous recombination deficiency- positive advanced cancers

Timothy A. Yap, Ronnie Shapira-Frommer, Iwona Lugowska, Tudor Ciuleanu, Miguel Quintela-Fandino, Özgür Özyılkan, Serhii Lysenko, Akira Hirasawa, Simcha Pollack, Rachel Salisbury, Alexander Gozman, Michele Maio

Cancer Res (2025) 85 (8_Supplement_2): CT004.

https://doi.org/10.1158/1538-7445.AM2025-CT004

Published: 25 April 2025

View articletitled, Abstract CT004: KEYLYNK-007: Tumor agnostic trial of olaparib plus pembrolizumab in homologous recombination repair mutation- and homologous recombination deficiency- positive advanced cancers

Journal Articles

Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Eiji Nakada, Tomohiro Fujiwara, Toshi Kunisada, Shota Takihira, Daisuke Ennishi, Hideki Yamamoto, Kiichiro Ninomiya, Shuta Tomida, Mashu Futagawa, Akira Hirasawa, Shinichi Toyooka, Toshifumi Ozaki

Cancer Res (2024) 84 (6_Supplement): 6456.

https://doi.org/10.1158/1538-7445.AM2024-6456

Published: 22 March 2024

View articletitled, Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Journal Articles

Abstract 1767: Molecular subclassification of gastrointestinal stromal tumors by genomic backgrounds

Hideki Yamamoto, Eiji Nakada, Seiji Kawano, Fumino Kato, Chika Fukano, Mashu Futagawa, Yusaku Urakawa, Risa Ohsumi, Sayaka Ueno, Hiroyuki Yanai, Akira Hirasawa

Cancer Res (2024) 84 (6_Supplement): 1767.

https://doi.org/10.1158/1538-7445.AM2024-1767

Published: 22 March 2024

View articletitled, Abstract 1767: Molecular subclassification of gastrointestinal stromal tumors by genomic backgrounds

Journal Articles

Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Shota Takihira, Eiji Nakata, Daisuke Yamada, Tatsunori Osone, Tomoka Takao, Takeshi Takarada, Akira Hirasawa, Takuto Itano, Tomohiro Fujiwara, Toshiyuki Kunisada, Toshifumi Ozaki

Cancer Res (2024) 84 (6_Supplement): 5649.

https://doi.org/10.1158/1538-7445.AM2024-5649

Published: 22 March 2024

View articletitled, Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Journal Articles

Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Cancer Res (2023) 83 (7_Supplement): 3225.

https://doi.org/10.1158/1538-7445.AM2023-3225

Published: 04 April 2023

View articletitled, Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Journal Articles

Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Astrid Murumägi, Daniela Ungureanu, Suleiman Khan, Akira Hirasawa, Mariliina Arjama, Katja Välimäki, Piia Mikkonen, Wilhelmiina Niininen, Ashwini Kumar, Samuli Eldfors, Teijo Pellinen, Vilja Pietiäinen, Andrus Mägi, Riitta Koivisto-Korander, Johanna Tapper, Mikko Loukovaara, Tero Aittokallio, Ralf Bützow, Olli Kallioniemi

Cancer Res (2019) 79 (13_Supplement): 2945.

https://doi.org/10.1158/1538-7445.AM2019-2945

Published: 01 July 2019

View articletitled, Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Journal Articles

Abstract 4274: The contribution of deleterious germ-line mutations of susceptibility genes to ovarian, fallopian tube, and peritoneal cancers in Japanese

Akira Hirasawa, Issei Imoto, Takuya Naruto, Tomoko Akahane, Wataru Yamagami, Nobuyuki Susumu, Hitoshi Tsuda, Daisuke Aoki

Cancer Res (2017) 77 (13_Supplement): 4274.

https://doi.org/10.1158/1538-7445.AM2017-4274

Published: 01 July 2017

View articletitled, Abstract 4274: The contribution of deleterious germ-line mutations of susceptibility genes to ovarian, fallopian tube, and peritoneal cancers in Japanese

Journal Articles

Abstract 410: Identifying ovarian cancer specific targeted drugs using high-throughput drug sensitivity profiles of primary cancer cells

Astrid Murumägi, Akira Hirasawa, Suleiman Khan, Daniela Ungureanu, Mariliina Arjama, Teijo Pellinen, Samuli Eldfors, Riitta Koivisto-Korander, Arto Leminen, Ralf Bützow, Tero Aittokallio, Olli Kallioniemi

Cancer Res (2017) 77 (13_Supplement): 410.

https://doi.org/10.1158/1538-7445.AM2017-410

Published: 01 July 2017

View articletitled, Abstract 410: Identifying ovarian cancer specific targeted drugs using high-throughput drug sensitivity profiles of primary cancer cells

Journal Articles

Abstract 307: GPR120/FFAR4 activation by fatty acid 16:4(n-3) plays a key role in resistance to chemotherapy

Julia Houthuijzen, Ilse Oosterom, Brian Hudson, Akira Hirasawa, Laura Daenen, Chelsea McLean, Steffen Hansen, Marijn van Jaarsveld, Daniel Peeper, sahar Jafari Sadatmand, Jeanine Roodhart, Chris van de Lest, Trond Ulven, Kenji Ishihara, Graeme Milligan, Emile Voest

Cancer Res (2016) 76 (14_Supplement): 307.

https://doi.org/10.1158/1538-7445.AM2016-307

Published: 15 July 2016

View articletitled, Abstract 307: GPR120/FFAR4 activation by fatty acid 16:4(n-3) plays a key role in resistance to chemotherapy

Journal Articles

Abstract 5126: Establishment of an esophageal small cell carcinoma cell line (TYUC-1)

Yutaka Shimada, Tomoyuki Okumura, Yoshinori Takei, Kazuaki Watanabe, Akira Hirasawa, Arito Yamane, Masahiko Nishiyama, Takuya Nagata, Kazuhiro Tsukada, Kazuharu Shimizu

Cancer Res (2015) 75 (15_Supplement): 5126.

https://doi.org/10.1158/1538-7445.AM2015-5126

Published: 01 August 2015

View articletitled, Abstract 5126: Establishment of an esophageal small cell carcinoma cell line (TYUC-1)

Journal Articles

Abstract 3746: Novel therapeutic possibilities for chemorefractory ovarian cancer patients identified by functional ex vivo drug sensitivity testing of primary cells from ascites

Astrid Murumägi, Akira Hirasawa, Mariliina Arjama, Katja Välimäki, Bhagwan Yadav, Jing Tang, Agnieszka Szwajda, Laura Turunen, John Patrick Mpindi, Teijo Pellinen, Krister Wennerberg, Ralf Bützow, Tero Aittokallio, Olli Kallioniemi

Cancer Res (2015) 75 (15_Supplement): 3746.

https://doi.org/10.1158/1538-7445.AM2015-3746

Published: 01 August 2015

View articletitled, Abstract 3746: Novel therapeutic possibilities for chemorefractory ovarian cancer patients identified by functional ex vivo drug sensitivity testing of primary cells from ascites

Journal Articles

Abstract 5384: Systematic high-throughput drug sensitivity and resistance testing (DSRT) of ovarian cancer cell lines indicates novel therapeutic possibilities with existing and emerging drugs

Akira Hirasawa, Astrid Murumägi, Mariliina Arjama, Bhagwan Yadav, John Patrick Mpindi, Krister Wennerberg, Tero Aittokallio, Daisuke Aoki, Olli Kallioniemi

Cancer Res (2014) 74 (19_Supplement): 5384.

https://doi.org/10.1158/1538-7445.AM2014-5384

Published: 01 October 2014

View articletitled, Abstract 5384: Systematic high-throughput drug sensitivity and resistance testing (DSRT) of ovarian cancer cell lines indicates novel therapeutic possibilities with existing and emerging drugs

Journal Articles

miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer

Tomohiko Tsuruta, Ken-ichi Kozaki, Atsushi Uesugi, Mayuko Furuta, Akira Hirasawa, Issei Imoto, Nobuyuki Susumu, Daisuke Aoki, Johji Inazawa

Cancer Res (2011) 71 (20): 6450–6462.

https://doi.org/10.1158/0008-5472.CAN-11-0364

Published: 12 October 2011

View articletitled, miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer

Includes: Supplementary data

Journal Articles

Abstract 4039: miR-196a is a novel diagnostic biomarker and therapeutic target for laryngeal cancer

Koichiro Saito, Koji Inagaki, Kosuke Uno, Yoko Ito, Toshiaki Sugita, Satoko Nakajo, Hideki Naganishi, Haruna Yabe, Akira Hirasawa, Keisuke Okubo, Kaoru Ogawa, Takeru Zama

Cancer Res (2010) 70 (8_Supplement): 4039.

https://doi.org/10.1158/1538-7445.AM10-4039

Published: 15 April 2010

View articletitled, Abstract 4039: miR-196a is a novel diagnostic biomarker and therapeutic target for laryngeal cancer

Journal Articles

Abstract #581: MicroRNA expression signature reveals putative diagnostic biomarkers for laryngeal cancer

Koichiro Saito, Keisuke Okubo, Hideki Naganishi, Koji Inagaki, Akira Hirasawa, Takeru Zama

Cancer Res (2009) 69 (9_Supplement): 581.

Published: 01 May 2009

View articletitled, Abstract #581: MicroRNA expression signature reveals putative diagnostic biomarkers for laryngeal cancer

Journal Articles

Possible involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines

Issei Imoto, Hideaki Tanami, Akira Hirasawa, Yasuhiro Yuki, Itaru Sonoda, Jun Inoue, Kohichiro Yasui, Akiko Misawa-Furihata, Yutaka Kawakami, Johji Inazawa

Cancer Res (2004) 64 (7_Supplement): 639.

Published: 01 April 2004

View articletitled, Possible involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines

Journal Articles

Amplification and consequent overexpression of PDZK1 within the 1q12-q22 amplicon is associated with drug-resistance phenotype in multiple myeloma

Johji Inazawa, Takemi Otsuki, Akira Hirasawa, Issei Imoto, Matsuo Yoshinobu, Shiroh Shimizu, Masashi Taniwaki, Jun Inoue

Cancer Res (2004) 64 (7_Supplement): 392.

Published: 01 April 2004

View articletitled, Amplification and consequent overexpression of PDZK1 within the 1q12-q22 amplicon is associated with drug-resistance phenotype in multiple myeloma

Journal Articles

Expression of cIAP1, a Target for 11q22 Amplification, Correlates with Resistance of Cervical Cancers to Radiotherapy

Issei Imoto, Hitoshi Tsuda, Akira Hirasawa, Masahiko Miura, Masaru Sakamoto, Setsuo Hirohashi, Johji Inazawa

Cancer Res (2002) 62 (17): 4860–4866.

Published: 01 September 2002

View articletitled, Expression of cIAP1, a Target for 11q22 Amplification, Correlates with Resistance of Cervical Cancers to Radiotherapy

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Abstract CT004: KEYLYNK-007: Tumor agnostic trial of olaparib plus pembrolizumab in homologous recombination repair mutation- and homologous recombination deficiency- positive advanced cancers

Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Abstract 1767: Molecular subclassification of gastrointestinal stromal tumors by genomic backgrounds

Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Abstract 4274: The contribution of deleterious germ-line mutations of susceptibility genes to ovarian, fallopian tube, and peritoneal cancers in Japanese

Abstract 410: Identifying ovarian cancer specific targeted drugs using high-throughput drug sensitivity profiles of primary cancer cells

Abstract 307: GPR120/FFAR4 activation by fatty acid 16:4(n-3) plays a key role in resistance to chemotherapy

Abstract 5126: Establishment of an esophageal small cell carcinoma cell line (TYUC-1)

Abstract 3746: Novel therapeutic possibilities for chemorefractory ovarian cancer patients identified by functional ex vivo drug sensitivity testing of primary cells from ascites

Abstract 5384: Systematic high-throughput drug sensitivity and resistance testing (DSRT) of ovarian cancer cell lines indicates novel therapeutic possibilities with existing and emerging drugs

miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer

Abstract 4039: miR-196a is a novel diagnostic biomarker and therapeutic target for laryngeal cancer

Abstract #581: MicroRNA expression signature reveals putative diagnostic biomarkers for laryngeal cancer

Possible involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines

Amplification and consequent overexpression of PDZK1 within the 1q12-q22 amplicon is associated with drug-resistance phenotype in multiple myeloma

Expression of cIAP1, a Target for 11q22 Amplification, Correlates with Resistance of Cervical Cancers to Radiotherapy

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