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Ajay P. Singh
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Journal Articles

Abstract LB312: Subtype- and race-specific differences in immune landscape of breast cancer

Amod Sharma, Kunwar Somesh Vikramdeo, Sarabjeet Kour Sudan, Mohammad Aslam Khan, Mohammad Tahir, James Elliot Carter, Cindy Nelson, Ajay P Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB312.
https://doi.org/10.1158/1538-7445.AM2024-LB312
Published: 05 April 2024
View article titled, Abstract LB312: Subtype- and race-specific differences in immune landscape of breast cancer
Journal Articles

Abstract 6233: Characterizing variants of uncertain significance in the tumor suppressor gene known as phosphatase and tensin homolog (PTEN)

Ajay P. Singh, Jasmine Wen, David Nguyen, Vedanta Khan, Kiran Dhami, Kaitlynn Meier-Ross, Benjamin Martin, Jesse T. Chao
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6233.
https://doi.org/10.1158/1538-7445.AM2024-6233
Published: 22 March 2024
View article titled, Abstract 6233: Characterizing variants of uncertain significance in the tumor suppressor gene known as phosphatase and tensin homolog (PTEN)
Journal Articles

Abstract 4369: CYP3A5 promotes aggressive and therapeutically resistant prostate cancer by modulating AR and Wnt signaling: Implications for racially disparate clinical outcomes

Jake McLean, Ajay P. Singh, Edwin Oh, Ranjana Mitra
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4369.
https://doi.org/10.1158/1538-7445.AM2024-4369
Published: 22 March 2024
View article titled, Abstract 4369: CYP3A5 promotes aggressive and therapeutically resistant prostate cancer by modulating AR and Wnt signaling: Implications for racially disparate clinical outcomes
Journal Articles

Abstract 5394: Nicotine-induced exosomal miR-3157-3p from prostate cancer cells promotes angiogenesis

Shubhangi Singh, Mohammad Aslam Khan, Shashi Anand, Sirin Saranyutanon, Sanjeev Kumar Srivastava, Seema Singh, Ajay P. Singh, Kunwar Somesh Vikramdeo
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5394.
https://doi.org/10.1158/1538-7445.AM2024-5394
Published: 22 March 2024
View article titled, Abstract 5394: Nicotine-induced exosomal miR-3157-3p from prostate cancer cells promotes angiogenesis
Journal Articles

Abstract 4602: Differences in tumor vascular density between smoker and non-smoker cancer patients

Shubhangi Singh, Mohammad Aslam Khan, Elba T. Herrera, Seema Singh, Ajay P. Singh, Santanu Dasgupta
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4602.
https://doi.org/10.1158/1538-7445.AM2023-4602
Published: 04 April 2023
View article titled, Abstract 4602: Differences in tumor vascular density between smoker and non-smoker cancer patients
Journal Articles

Abstract 3318: Frequent loss of CACNA1C, a calcium voltage-gated channel subunit is associated with lung adenocarcinoma progression and poor prognosis

Saanvi Dasgupta, Srijan Acharya, Mohammad A. Khan, Paramahansa Pramanik, Stephen M. Marbut, Furhan Yunus, Jose N. Galeas, Seema Singh, Ajay P. Singh, Santanu Dasgupta
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3318.
https://doi.org/10.1158/1538-7445.AM2023-3318
Published: 04 April 2023
View article titled, Abstract 3318: Frequent loss of CACNA1C, a calcium voltage-gated channel subunit is associated with lung adenocarcinoma progression and poor prognosis
Journal Articles

Abstract 3204: Differential expression of angiogenesis-associated genes in smoker and non-smoker lung adenocarcinoma patients

Shubhangi Singh, Santanu Dasgupta, Elba A. Turbat-Herrera, Seema Singh, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3204.
https://doi.org/10.1158/1538-7445.AM2022-3204
Published: 15 June 2022
View article titled, Abstract 3204: Differential expression of angiogenesis-associated genes in smoker and non-smoker lung adenocarcinoma patients
Journal Articles

Abstract 2212: Racially disparate serum levels of inflammatory cytokines, satiety and stress hormones, and exosomal microRNAs in women with or without a breast cancer diagnosis

Sarabjeet Kour Sudan, Kunwar Somesh Vikramdeo, Amod Sharma, Sachin Kumar Deshmukh, Sanjeev Kumar Srivastava, Teja Poosarla, Nicolette P. Holliday, Donna L. Dyess, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2212.
https://doi.org/10.1158/1538-7445.AM2022-2212
Published: 15 June 2022
View article titled, Abstract 2212: Racially disparate serum levels of inflammatory cytokines, satiety and stress hormones, and exosomal microRNAs in women with or without a breast cancer diagnosis
Journal Articles

Abstract 1546: Cortisol induces the expression of miR-143-3p/miR-145 cluster in macrophages to affect macrophage polarization via reprogramming of glucose metabolism

Amod Sharma, Kunwar Somesh Vikramdeo, Sarabjeet Kour Sudan, Sachin Kumar Deshmukh, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1546.
https://doi.org/10.1158/1538-7445.AM2022-1546
Published: 15 June 2022
View article titled, Abstract 1546: Cortisol induces the expression of miR-143-3p/miR-145 cluster in macrophages to affect macrophage polarization via reprogramming of glucose metabolism
Journal Articles

Abstract 520: MYB exhibits racially disparate overexpression and clinicopathologic association in prostate cancer: significance as a predictor of biochemical recurrence

Mohammad Aslam Khan, Srijan Acharya, Shashi Anand, Fnu Sameeta, James E. Carter, Oliver J. Semmes, Dean A. Troyer, Seema Singh, Santanu Dasgupta, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 520.
https://doi.org/10.1158/1538-7445.AM2022-520
Published: 15 June 2022
View article titled, Abstract 520: MYB exhibits racially disparate overexpression and clinicopathologic association in prostate cancer: significance as a predictor of biochemical recurrence
Journal Articles

Abstract 2601: Expression and clinicopathological association of RABs in pancreatic cancer

Shashi Anand, Haseeb Zubair, Mohammad Aslam Khan, Seema Singh, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2601.
https://doi.org/10.1158/1538-7445.AM2020-2601
Published: 15 August 2020
View article titled, Abstract 2601: Expression and clinicopathological association of RABs in pancreatic cancer
Journal Articles

Abstract 1489: Exosomes are key players in nicotine-induced angiogenesis

Shubhangi Singh, Sirin Saranyutanon, Mohammad Aslam Khan, Sanjeev Kumar Srivastava, Seema Singh, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1489.
https://doi.org/10.1158/1538-7445.AM2020-1489
Published: 15 August 2020
View article titled, Abstract 1489: Exosomes are key players in nicotine-induced angiogenesis
Journal Articles

Abstract 5070: LIN28A-mediated repression of Let-7a is involved in resistin-induced STAT3 upregulation in breast cancer cells and supports growth and stemness properties

Sachin Kumar Deshmukh, Sanjeev K. Srivastava, Haseeb Zubair, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5070.
https://doi.org/10.1158/1538-7445.AM2020-5070
Published: 15 August 2020
View article titled, Abstract 5070: LIN28A-mediated repression of Let-7a is involved in resistin-induced STAT3 upregulation in breast cancer cells and supports growth and stemness properties
Journal Articles

Abstract 6259: Exosomal formulation escalates cellular uptake of honokiol leading to enhanced antitumor efficacy in pancreatic cancer

Mohammad Aslam Khan, Rajashekhar Kanchanapally, Sachin Kumar Deshmukh, Sanjeev K. Srivastava, Seema Singh, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6259.
https://doi.org/10.1158/1538-7445.AM2020-6259
Published: 15 August 2020
View article titled, Abstract 6259: Exosomal formulation escalates cellular uptake of honokiol leading to enhanced antitumor efficacy in pancreatic cancer
Journal Articles

Abstract 992: Comparative analyses of drug-loaded exosomal preparations from different cell types reveal distinctive loading capability, yield, and anti-tumor efficacies

RAJASHEKHAR KANCHANAPALLY, Sachin Kumar Deshmukh, Suhash Reddy Chavva, Nikhil Tyagi, Sanjeev Kumar Srivastava, Girijesh Kumar Patel, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 992.
https://doi.org/10.1158/1538-7445.AM2019-992
Published: 01 July 2019
View article titled, Abstract 992: Comparative analyses of drug-loaded exosomal preparations from different cell types reveal distinctive loading capability, yield, and anti-tumor efficacies
Journal Articles

Abstract 1911: Bi-directional cross-talk of pancreatic cancer and stellate cells, mediated through CXCR4 and hedgehog pathways, promotes chemoresistance via its effect on gemcitabine metabolism, ROS detoxification and cancer stemness

Mohammad Aslam Khan, Girijesh K. Patel, Sanjeev K. Srivastava, Sumit Arora, Haseeb Zubair, James Elliot Carter, Bin Wang, Seema Singh, Moh’d Khushman, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1911.
https://doi.org/10.1158/1538-7445.AM2019-1911
Published: 01 July 2019
View article titled, Abstract 1911: Bi-directional cross-talk of pancreatic cancer and stellate cells, mediated through CXCR4 and hedgehog pathways, promotes chemoresistance via its effect on gemcitabine metabolism, ROS detoxification and cancer stemness
Journal Articles

Abstract 3639: EGCG-gold nanoparticles exhibit greater anti-tumor activity over conventional gold nanoparticles or EGCG due to potential synergistic interactions

Suhash Reddy Chavva, Sachin Kumar Deshmukh, Rajashekhar Kanchanapally, Nikhil Tyagi, Jason W. Coym, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3639.
https://doi.org/10.1158/1538-7445.AM2019-3639
Published: 01 July 2019
View article titled, Abstract 3639: EGCG-gold nanoparticles exhibit greater anti-tumor activity over conventional gold nanoparticles or EGCG due to potential synergistic interactions
Journal Articles

Abstract 5158: Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival

Mary C. Patton, Haseeb Zubair, Mohammad Aslam Khan, Seema Singh, Ajay P. Singh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5158.
https://doi.org/10.1158/1538-7445.AM2019-5158
Published: 01 July 2019
View article titled, Abstract 5158: Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival
Journal Articles

Abstract 113: Gemcitabine treatment induces immunosuppressive microenvironment in pancreatic cancer by promoting the infiltration, growth, and polarization of macrophages

Sachin Kumar Deshmukh, Arun Bhardwaj, Nikhil Tyagi, Mohammad Aslam Khan, Sanjeev K. Srivastava, Ahmed AL-Ghadhban, Kari Dugger, James E. Carter, Ajay P. Singh, Seema Singh
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 113.
https://doi.org/10.1158/1538-7445.AM2018-113
Published: 01 July 2018
View article titled, Abstract 113: Gemcitabine treatment induces immunosuppressive microenvironment in pancreatic cancer by promoting the infiltration, growth, and polarization of macrophages
Journal Articles

Abstract 949: Resistin potentiates stemness and chemoresistance of breast cancer cells through STAT3 activation: implications in breast cancer health disparity

Sachin Kumar Deshmukh, Arun Bhardwaj, Sanjeev K. Srivastava, Nikhil Tyagi, Ahmed Al-Ghadhban, Ajay P. Singh, Donna L. Dyess, James E. Carter, Seema Singh
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 949.
https://doi.org/10.1158/1538-7445.AM2017-949
Published: 01 July 2017
View article titled, Abstract 949: Resistin potentiates stemness and chemoresistance of breast cancer cells through STAT3 activation: implications in breast cancer health disparity