1-20 of 120
Adrian L. Harris
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner

Zijing Wang, Nan Zhang, Miao Zhang, Yao Jiang, Aik Seng Ng, Esther Bridges, Wei Zhang, Xin Zeng, Qi Luo, Jiabien Liang, Balázs Győrffy, Philip Hublitz, Zhu Liang, Roman Fischer, David Kerr, Adrian L. Harris, Shijie Cai
Journal: Cancer Research
Cancer Res (2023) 83 (20): 3400–3413.
https://doi.org/10.1158/0008-5472.CAN-22-3471
Published: 13 October 2023
View article titled, GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner
Open the PDF for GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner in another window
Includes: Supplementary data
Journal Articles

Abstract A020: Calcitonin receptor-like receptor is expressed in blood vessels in clear cell renal cell carcinoma and upregulated in endothelial cells co-cultured with tumor cells

Matthew A. Morfitt, John Greenman, Anthony Maraveyas, Adrian L. Harris, Leonid L. Nikitenko
Journal: Cancer Research
Cancer Res (2023) 83 (16_Supplement): A020.
https://doi.org/10.1158/1538-7445.KIDNEY23-A020
Published: 15 August 2023
View article titled, Abstract A020: Calcitonin receptor-like receptor is expressed in blood vessels in clear cell renal cell carcinoma and upregulated in endothelial cells co-cultured with tumor cells
Journal Articles

Abstract 5813: Glycogen synthesis as potential novel target in triple negative breast cancer: Glycogen synthase 1 expression in human breast cancers and the impact of downregulation on proliferation of preclinical models

Ellen C. De Heer, Christos E. Zois, Esther Bridges, Mieke C. Zwager, Tineke van der Sluis, Bert van der Vegt, Carolien P. Schröder, Steven de Jong, Adrian L. Harris, Mathilde Jalving
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5813.
https://doi.org/10.1158/1538-7445.AM2022-5813
Published: 15 June 2022
View article titled, Abstract 5813: Glycogen synthesis as potential novel target in triple negative breast cancer: Glycogen synthase 1 expression in human breast cancers and the impact of downregulation on proliferation of preclinical models
Journal Articles

The Landscape of the Heritable Cancer Genome

Viola Fanfani, Luca Citi, Adrian L. Harris, Francesco Pezzella, Giovanni Stracquadanio
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2588–2599.
https://doi.org/10.1158/0008-5472.CAN-20-3348
Published: 15 May 2021
View article titled, The Landscape of the Heritable Cancer Genome
Open the PDF for The Landscape of the Heritable Cancer Genome in another window
Includes: Supplementary data
Journal Articles

Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types

Ana Miar, Esther Arnaiz, Esther Bridges, Shaunna Beedie, Adam P. Cribbs, Damien J. Downes, Robert A. Beagrie, Jan Rehwinkel, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5245–5256.
https://doi.org/10.1158/0008-5472.CAN-19-2306
Published: 02 December 2020
View article titled, Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types
Open the PDF for Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types in another window
Includes: Supplementary data
Journal Articles

Abstract 240: Inhibition of glycogen degradation sensitizes glioblastoma cells to ionizing radiation

Anne M. Hendriks, Christos E. Zois, Syed B. Haider, Elisabete Pires, Dimitra Kalamida, Christoffer Lagerholm, John Morris, James S. McCullagh, Rudolf S. Fehrmann, Wilfred F. den Dunnen, Adrian L. Harris, Mathilde Jalving
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 240.
https://doi.org/10.1158/1538-7445.AM2020-240
Published: 15 August 2020
View article titled, Abstract 240: Inhibition of glycogen degradation sensitizes glioblastoma cells to ionizing radiation
Journal Articles

Abstract 3563: Fatty acid binding protein 7 regulates beige fat-like differentiation of breast cancer cells and thermogenesis

Masahiro Kawashima, Karim Bensaad, Christos Zois, Alessandro Barberis, Esther Bridges, Christoffer Lagerholm, Ruslan I. Dmitriev, Masakazu Toi, Dmitri B. Papkovsky, Francesca Buffa, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3563.
https://doi.org/10.1158/1538-7445.AM2020-3563
Published: 15 August 2020
View article titled, Abstract 3563: Fatty acid binding protein 7 regulates beige fat-like differentiation of breast cancer cells and thermogenesis
Journal Articles

Abstract 521: Downregulation of type I IFN response in hypoxia as a possible mechanism of immune escape

Ana Miar, Jan Rehwinkel, Christos Zois, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 521.
https://doi.org/10.1158/1538-7445.AM2019-521
Published: 01 July 2019
View article titled, Abstract 521: Downregulation of type I IFN response in hypoxia as a possible mechanism of immune escape
Journal Articles

miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense

Marina Pajic, Danielle Froio, Sheridan Daly, Louise Doculara, Ewan Millar, Peter H. Graham, Alison Drury, Angela Steinmann, Charles E. de Bock, Alice Boulghourjian, Anaiis Zaratzian, Susan Carroll, Joanne Toohey, Sandra A. O’Toole, Adrian L Harris, Francesca M. Buffa, Harriet E. Gee, Georgina E. Hollway, Timothy J. Molloy
Journal: Cancer Research
Cancer Res (2018) 78 (2): 501–515.
https://doi.org/10.1158/0008-5472.CAN-16-3105
Published: 15 January 2018
View article titled, miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense
Open the PDF for miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense in another window
Includes: Supplementary data
Journal Articles

Abstract 4512: The landscape of hypoxia-driven alternative splicing in breast cancer

Hani Choudhry, Spyridon Oikonomopoulos, Peng Yu, Cristina Ivan, Mircea Ivan, Adrian L. Harris, Jiannis Ragoussis
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4512.
https://doi.org/10.1158/1538-7445.AM2017-4512
Published: 01 July 2017
View article titled, Abstract 4512: The landscape of hypoxia-driven alternative splicing in breast cancer
Journal Articles

Abstract 777: ELTD1/ADGRL4, a novel adhesion GPCR regulator of tumour angiogenesis, suppresses lipid metabolism in endothelial cells, and is upregulated in breast cancer endothelium and epithelium

David M. Favara, Madhulika Nambiar, Helen Sheldon, Massimo Masiero, Demin Li, Ali Jazayeri, Alison H. Banham, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 777.
https://doi.org/10.1158/1538-7445.AM2017-777
Published: 01 July 2017
View article titled, Abstract 777: ELTD1/ADGRL4, a novel adhesion GPCR regulator of tumour angiogenesis, suppresses lipid metabolism in endothelial cells, and is upregulated in breast cancer endothelium and epithelium
Journal Articles

Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth

Alan McIntyre, Alzbeta Hulikova, Ioanna Ledaki, Cameron Snell, Dean Singleton, Graham Steers, Peter Seden, Dylan Jones, Esther Bridges, Simon Wigfield, Ji-Liang Li, Angela Russell, Pawel Swietach, Adrian L. Harris
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (13): 3744–3755.
https://doi.org/10.1158/0008-5472.CAN-15-1862
Published: 30 June 2016
View article titled, Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth
Open the PDF for Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract B1-56: Distinct roles of copy number and loss-of-heterozygosity in predicting prognosis for breast cancer patients

Ruud GPM van Stiphout, Antoine deWeck, Laura Winchester, Syed A. Haider, Jiannis Ragoussis, Adrian L. Harris, Chris Holmes, Francesca M. Buffa
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-56.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-56
Published: 15 November 2015
View article titled, Abstract B1-56: Distinct roles of copy number and loss-of-heterozygosity in predicting prognosis for breast cancer patients
Journal Articles

Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors

Ferdia A. Gallagher, Helen Sladen, Mikko I. Kettunen, Eva M. Serrao, Tiago B. Rodrigues, Alan Wright, Andrew B. Gill, Sarah McGuire, Thomas C. Booth, Joan Boren, Alan McIntyre, Jodi L. Miller, Shen-Han Lee, Davina Honess, Sam E. Day, De-En Hu, William J. Howat, Adrian L. Harris, Kevin M. Brindle
Journal: Cancer Research
Cancer Res (2015) 75 (19): 4109–4118.
https://doi.org/10.1158/0008-5472.CAN-15-0857
Published: 30 September 2015
View article titled, Carbonic Anhydrase Activity Monitored <em>In Vivo</em> by Hyperpolarized <sup>13</sup>C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors
Open the PDF for Carbonic Anhydrase Activity Monitored <em>In Vivo</em> by Hyperpolarized <sup>13</sup>C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 3750: Genomic alterations underlie a pan-cancer metabolic transcriptome shift

Syed Haider, Alan McIntyre, Ruud GPM van Stiphout, Laura M. Winchester, Simon Wigfield, Adrian L. Harris, Francesca M. Buffa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3750.
https://doi.org/10.1158/1538-7445.AM2015-3750
Published: 01 August 2015
View article titled, Abstract 3750: Genomic alterations underlie a pan-cancer metabolic transcriptome shift
Journal Articles

Abstract 2903: Differential regulation of LC3 A and B, GABARAPL 1 and 2 autophagy genes by micro-environmental stress and role in breast cancer survival

Christos E. Zois, Syed Haider, Simon Wigfield, Alexandra Giatromanolaki, Efthimios Sivridis, Karl Morten, Ioannis Roxanis, Russell Leek, Francesca Buffa, Michael Koukourakis, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2903.
https://doi.org/10.1158/1538-7445.AM2015-2903
Published: 01 August 2015
View article titled, Abstract 2903: Differential regulation of LC3 A and B, GABARAPL 1 and 2 autophagy genes by micro-environmental stress and role in breast cancer survival
Journal Articles

Abstract P2-05-01: The non-coding transcriptome of hypoxic breast cancer: Novel insights of clinical relevant long non-coding RNA in hypoxia signalling

Hani Choudhry, Johannes Schodel, Ashwag Albukhari, Syed Haider, Francesca Buffa, Peter J Ratcliffe, David R Mole, Ioannis Ragousis, Adrian L Harris
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P2-05-01.
https://doi.org/10.1158/1538-7445.SABCS14-P2-05-01
Published: 01 May 2015
View article titled, Abstract P2-05-01: The non-coding transcriptome of hypoxic breast cancer: Novel insights of clinical relevant long non-coding RNA in hypoxia signalling
Journal Articles

Abstract 3334: The role of nuclear HER3 in breast cancer resistance

Patrick Ming Kuen Tang, Ui Soon Khoo, Adrian L. Harris, Anthony Kong
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3334.
https://doi.org/10.1158/1538-7445.AM2014-3334
Published: 01 October 2014
View article titled, Abstract 3334: The role of nuclear HER3 in breast cancer resistance
Journal Articles

Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth.

Alan McIntyre, Alzbeta Hulikova, Ioanna Ledaki, Peter Seden, Helen Turley, Dylan Jones, Angela Russell, Pawel Swietach, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4053.
https://doi.org/10.1158/1538-7445.AM2013-4053
Published: 15 April 2013
View article titled, Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth.
Journal Articles

Abstract 3942: The role of vHL and REDD1 in predicting sensitivity to targeted therapies in renal cell carcinoma

Christopher Blick, Anassuya Ramachandran, Robert McCormick, David Cranston, Adrian L. Harris
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3942.
https://doi.org/10.1158/1538-7445.AM2012-3942
Published: 15 April 2012
View article titled, Abstract 3942: The role of vHL and REDD1 in predicting sensitivity to targeted therapies in renal cell carcinoma