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Journal Articles

Abstract 3582: PPAR gamma acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding

Free
LIfeng Tian, Xuanmao Jiao, Chenguang Wang, Adam Ertel, Raymond Soccio, Eric R. Chen, Balázs Győrffy, Gabriele Di Sante, Zhijiu Zhong, Sankar Addya, Peter A. McCue, Andrew V. Kossenkov, Joanna Achinger-Kawecka, Susan Clark, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3582.
https://doi.org/10.1158/1538-7445.AM2024-3582
Published: 22 March 2024
View articletitled, Abstract 3582: PPAR gamma acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding
Journal Articles

Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression

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Patrizia Porazzi, Svetlana Petruk, Luca Pagliaroli, Marco De Dominici, David Deming, II, Matthew V. Puccetti, Saul Kushinsky, Gaurav Kumar, Valentina Minieri, Elisa Barbieri, Sandra Deliard, Alexis Grande, Marco Trizzino, Alessandro Gardini, Eli Canaani, Neil Palmisiano, Pierluigi Porcu, Adam Ertel, Paolo Fortina, Christine M. Eischen, Alexander Mazo, Bruno Calabretta
Journal: Cancer Research
Cancer Res (2022) 82 (3): 458–471.
https://doi.org/10.1158/0008-5472.CAN-21-1297
Published: 02 February 2022
View articletitled, Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression
Open the PDF for Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression in another window
Includes: Supplementary data
Journal Articles

Abstract PS17-58: Pparg1 induces an EGF-EphA2 receptor tyrosine kinase module to promote ErbB2- mammary adenocarcinoma in mice

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Richard G Pestell, Xuanmao Jiao, Andrew V Kossenkov, Adam Ertel, Wei Tong, Zhao Zhang, Peter A McCue
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS17-58.
https://doi.org/10.1158/1538-7445.SABCS20-PS17-58
Published: 15 February 2021
View articletitled, Abstract PS17-58: Pparg1 induces an EGF-EphA2 receptor tyrosine kinase module to promote ErbB2- mammary adenocarcinoma in mice
Journal Articles

Abstract 5469: iCVA- A knowledge-based cancer variation annotation application

Free
Gaurav Kumar, Melanie Kelly, Paolo Fortina, Adam Ertel
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5469.
https://doi.org/10.1158/1538-7445.AM2020-5469
Published: 15 August 2020
View articletitled, Abstract 5469: iCVA- A knowledge-based cancer variation annotation application
Journal Articles

Abstract 1730: DACH1 gene deletion extends portraits of human prostate cancer

Free
Xuanmao Jiao, Gabriele Di Sante, Zhiping Li, Agnese Di Rocco, Min Wang, Adam Ertel, Peter A. McCue, Andrew P. South, Carlos Cordon-Cardo, Matthew P. Stokes, Marco Marra, Steven J. Jones, Andrew Kossenkov, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1730.
https://doi.org/10.1158/1538-7445.AM2019-1730
Published: 01 July 2019
View articletitled, Abstract 1730: DACH1 gene deletion extends portraits of human prostate cancer
Journal Articles

RB Loss Promotes Prostate Cancer Metastasis

Free
Chellappagounder Thangavel, Ettickan Boopathi, Yi Liu, Alex Haber, Adam Ertel, Anshul Bhardwaj, Sankar Addya, Noelle Williams, Stephen J. Ciment, Paolo Cotzia, Jeffry L. Dean, Adam Snook, Chris McNair, Matt Price, James R. Hernandez, Shuang G. Zhao, Ruth Birbe, James B. McCarthy, Eva A. Turley, Kenneth J. Pienta, Felix Y. Feng, Adam P. Dicker, Karen E. Knudsen, Robert B. Den
Journal: Cancer Research
Cancer Res (2017) 77 (4): 982–995.
https://doi.org/10.1158/0008-5472.CAN-16-1589
Published: 14 February 2017
View articletitled, RB Loss Promotes Prostate Cancer Metastasis
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Includes: Supplementary data
Journal Articles

v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1

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Xiaoming Ju, Xuanmao Jiao, Adam Ertel, Mathew C. Casimiro, Gabriele Di Sante, Shengqiong Deng, Zhiping Li, Agnese Di Rocco, Tingting Zhan, Adam Hawkins, Tanya Stoyanova, Sebastiano Andò, Alessandro Fatatis, Michael P. Lisanti, Leonard G. Gomella, Lucia R. Languino, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2016) 76 (22): 6723–6734.
https://doi.org/10.1158/0008-5472.CAN-15-3327
Published: 14 November 2016
View articletitled, v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1
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Includes: Supplementary data
Journal Articles

Abstract B10: Cyclin D1 restrains oncogene-induced autophagy via phosphorylation of LKB1

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Mathew Casimiro, Gabriele Di Sante, Emanuele Loro, Timothy Pestell, Sara Bisetto, Marco Velasco-Velázquez, Xuanmao Jiao, Zhiping Li, Chenguang Wang, Daniel Ly, Bin Zheng, Shen Che-Hung, Adam Ertel, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2016) 76 (3_Supplement): B10.
https://doi.org/10.1158/1538-7445.FBCR15-B10
Published: 07 April 2016
View articletitled, Abstract B10: Cyclin D1 restrains oncogene-induced autophagy via phosphorylation of LKB1
Journal Articles

Abstract 1844: Genome wide analysis of AR-cell cycle interplay reveals novel functions in cancer

Free
Christopher McNair, Jonathan Goodwin, Michael Augello, Alfonso Urbanucci, Matthew Schiewer, Clay Comstock, Adam Ertel, Liguo Wang, Qianben Wang, Ian Mills, Wei Li, Jason Carroll, Karen Knudsen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1844.
https://doi.org/10.1158/1538-7445.AM2015-1844
Published: 01 August 2015
View articletitled, Abstract 1844: Genome wide analysis of AR-cell cycle interplay reveals novel functions in cancer
Journal Articles

The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module

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Ke Chen, Kongming Wu, Xuanmao Jiao, Liping Wang, Xiaoming Ju, Min Wang, Gabriele Di Sante, Shaohua Xu, Qiong Wang, Kevin Li, Xin Sun, Congwen Xu, Zhiping Li, Mathew C. Casimiro, Adam Ertel, Sankar Addya, Peter A. McCue, Michael P. Lisanti, Chenguang Wang, Richard J. Davis, Graeme Mardon, Richard G. Pestell
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (10): 1992–2004.
https://doi.org/10.1158/0008-5472.CAN-14-0611
Published: 13 May 2015
View articletitled, The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module
Open the PDF for The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module in another window
Includes: Supplementary data
Journal Articles

CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines

Free
Daniela Sicoli, Xuanmao Jiao, Xiaoming Ju, Marco Velasco-Velazquez, Adam Ertel, Sankar Addya, Zhiping Li, Sebastiano Andò, Alessandro Fatatis, Bishnuhari Paudyal, Massimo Cristofanilli, Mathew L. Thakur, Michael P. Lisanti, Richard G. Pestell
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (23): 7103–7114.
https://doi.org/10.1158/0008-5472.CAN-14-0612
Published: 30 November 2014
View articletitled, CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines
Open the PDF for CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines in another window
Includes: Supplementary data
Journal Articles

Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and Translation

Free
Kongming Wu, Ke Chen, Chenguang Wang, Xuanmao Jiao, Liping Wang, Jie Zhou, Jing Wang, Zhiping Li, Sankar Addya, Poul H. Sorensen, Michael P. Lisanti, Andrew Quong, Adam Ertel, Richard G. Pestell
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (3): 829–839.
https://doi.org/10.1158/0008-5472.CAN-13-2466
Published: 02 February 2014
View articletitled, Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and Translation
Open the PDF for Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and Translation in another window
Includes: Supplementary data
Journal Articles

Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint

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Xiaoming Ju, Mathew C. Casimiro, Michael Gormley, Hui Meng, Xuanmao Jiao, Sanjay Katiyar, Marco Crosariol, Ke Chen, Min Wang, Andrew A. Quong, Michael P. Lisanti, Adam Ertel, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2014) 74 (2): 508–519.
https://doi.org/10.1158/0008-5472.CAN-13-1313
Published: 16 January 2014
View articletitled, Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Open the PDF for Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint in another window
Includes: Supplementary data
Journal Articles

EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1

Free
Kongming Wu, Zhaoming Li, Shaoxin Cai, Lifeng Tian, Ke Chen, Jing Wang, Junbo Hu, Ye Sun, Xue Li, Adam Ertel, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4488–4499.
https://doi.org/10.1158/0008-5472.CAN-12-4078
Published: 15 July 2013
View articletitled, EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1
Open the PDF for EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1 in another window
Includes: Supplementary data
Journal Articles

Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells

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Ke Chen, Kongming Wu, Shaoxin Cai, Wei Zhang, Jie Zhou, Jing Wang, Adam Ertel, Zhiping Li, Hallgeir Rui, Andrew Quong, Michael P. Lisanti, Aydin Tozeren, Ceylan Tanes, Sankar Addya, Michael Gormley, Chenguang Wang, Steven B. McMahon, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2013) 73 (11): 3262–3274.
https://doi.org/10.1158/0008-5472.CAN-12-3191
Published: 30 May 2013
View articletitled, Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells
Open the PDF for Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells in another window
Includes: Supplementary data
Journal Articles

Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures

Free
Xiaoming Ju, Adam Ertel, Mathew C. Casimiro, Zuoren Yu, Hui Meng, Peter A. McCue, Rhonda Walters, Paolo Fortina, Michael P. Lisanti, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2013) 73 (2): 978–989.
https://doi.org/10.1158/0008-5472.CAN-12-2133
Published: 16 January 2013
View articletitled, Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures
Open the PDF for Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures in another window
Includes: Supplementary data
Journal Articles

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

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Marco Velasco-Velázquez, Xuanmao Jiao, Marisol De La Fuente, Timothy G. Pestell, Adam Ertel, Michael P. Lisanti, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2012) 72 (15): 3839–3850.
https://doi.org/10.1158/0008-5472.CAN-11-3917
Published: 31 July 2012
View articletitled, CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Open the PDF for CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 3388: Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia

Free
Agnieszka Witkiewicz, Adam Ertel, Erik S. Knudsen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3388.
https://doi.org/10.1158/1538-7445.AM2012-3388
Published: 15 April 2012
View articletitled, Abstract 3388: Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia
Journal Articles

Mammary Gland Selective Excision of c-Jun Identifies Its Role in mRNA Splicing

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Sanjay Katiyar, Xuanmao Jiao, Sankar Addya, Adam Ertel, Yolanda Covarrubias, Vanessa Rose, Mathew C. Casimiro, Jie Zhou, Michael P. Lisanti, Talat Nasim, Paolo Fortina, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2012) 72 (4): 1023–1034.
https://doi.org/10.1158/0008-5472.CAN-11-3647
Published: 14 February 2012
View articletitled, Mammary Gland Selective Excision of c-Jun Identifies Its Role in mRNA Splicing
Open the PDF for Mammary Gland Selective Excision of c-Jun Identifies Its Role in mRNA Splicing in another window
Includes: Supplementary data
Journal Articles

Abstract 3906: Gene expression profiling of ductal carcinoma in situ reveals novel alterations in the tumor and stromal compartments related to progession and outcome of invasive breast cancer

Free
Agnieszka K. Witkiewicz, Adam Ertel, Jessica Kline, Elai Davicioni, Erik S. Knudsen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3906.
https://doi.org/10.1158/1538-7445.AM2011-3906
Published: 15 April 2011
View articletitled, Abstract 3906: Gene expression profiling of ductal carcinoma in situ reveals novel alterations in the tumor and stromal compartments related to progession and outcome of invasive breast cancer