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Abstract 321: Inhibition of CD39 results in elevated ATP and activation of myeloid cells to promote anti-tumor immunity

Christine E. Bowman, Ada Chen, Damie Juat, Kaustubh Parashar, Julie Clor, Hema Singh, Ritu Kushwaha, Bryan Handlos, Suan Liu, Janine Kline, Xiaoning Zhao, Hyock Joo Kwon, David Green, Stephen W. Young, Ester Fernandez-Salas, Matthew J. Walters, Nigel P. Walker

Cancer Res (2022) 82 (12_Supplement): 321.

DOI: https://doi.org/10.1158/1538-7445.AM2022-321

Published: 15 June 2022

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Journal Articles

Abstract 1756: Discovery and characterization of AB680, a potent and selective small-molecule CD73 inhibitor for cancer immunotherapy

Kenneth V. Lawson, Lixia Jin, Jenna L. Jeffrey, Jarek Kalisiak, Fangfang Yin, Kristen Zhang, Ada Chen, Debbie Swinarski, Matt J. Walters, Steve Young, Ulrike Schindler, Powers P. Jay

Cancer Res (2018) 78 (13_Supplement): 1756.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1756

Published: 01 July 2018

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Journal Articles

Abstract 2640: Small-molecule inhibitors of CD73, CD39 and A_2aR: Three anti-cancer targets in the ATP/adenosine signaling pathway

Ulrike Schindler, Joanne B. Tan, Matt Walters, Annette Becker, Fangfang Yin, Ada Chen, Yu Chen, Wan Hsin Lim, Steve Young, Manmohan Leleti, Jay Powers, Juan C. Jaen

Cancer Res (2017) 77 (13_Supplement): 2640.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2640

Published: 01 July 2017

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Journal Articles

Abstract 3663: Discovery of sulfonamide-piperidinones as potent inhibitors of the MDM2-p53 protein-protein interaction

Cancer Res (2015) 75 (15_Supplement): 3663.

DOI: https://doi.org/10.1158/1538-7445.AM2015-3663

Published: 01 August 2015

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Journal Articles

Methylation of CpG in a Small Region of the hMLH1 Promoter Invariably Correlates with the Absence of Gene Expression

Guoren Deng, Ada Chen, Joe Hong, Hiun Suk Chae, Young S. Kim

Cancer Res (1999) 59 (9): 2029.

Published: 01 May 1999

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Abstract 321: Inhibition of CD39 results in elevated ATP and activation of myeloid cells to promote anti-tumor immunity

Abstract 1756: Discovery and characterization of AB680, a potent and selective small-molecule CD73 inhibitor for cancer immunotherapy

Abstract 2640: Small-molecule inhibitors of CD73, CD39 and A_2aR: Three anti-cancer targets in the ATP/adenosine signaling pathway

Abstract 3663: Discovery of sulfonamide-piperidinones as potent inhibitors of the MDM2-p53 protein-protein interaction

Methylation of CpG in a Small Region of the hMLH1 Promoter Invariably Correlates with the Absence of Gene Expression

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AACR Journals

Abstract 321: Inhibition of CD39 results in elevated ATP and activation of myeloid cells to promote anti-tumor immunity

Abstract 1756: Discovery and characterization of AB680, a potent and selective small-molecule CD73 inhibitor for cancer immunotherapy

Abstract 2640: Small-molecule inhibitors of CD73, CD39 and A2aR: Three anti-cancer targets in the ATP/adenosine signaling pathway

Abstract 3663: Discovery of sulfonamide-piperidinones as potent inhibitors of the MDM2-p53 protein-protein interaction

Methylation of CpG in a Small Region of the hMLH1 Promoter Invariably Correlates with the Absence of Gene Expression

Email alerts

AACR Journals

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Abstract 2640: Small-molecule inhibitors of CD73, CD39 and A_2aR: Three anti-cancer targets in the ATP/adenosine signaling pathway