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Journal Articles

Abstract OT2-06-01: Highly innovative personalized RNA-immunotherapy for patients with triple negative breast cancer

M Schmidt, S Bolte, K Frenzel, L Heesen, E Derhovanessian, V Bukur, M Diken, J Gruetzner, S Kreiter, A Klein, A Kuhn, D Langer, M Loewer, H Lindman, A Schneeweiss, O Tuereci, U Sahin
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): OT2-06-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-OT2-06-01
Published: 15 February 2019
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Journal Articles

Abstract OT1-10-01: DETECT III/IV study trial – The multicenter study program in patients with HER2-negative metastatic breast cancer and circulating tumor cells

S Krause, T Friedl, T Romashova, PA Fasching, A Schneeweiss, V Müller, F-A Taran, P Arkadius, T Marie, A De Gregorio, F Meier-Stiegen, J Huober, W Janni, T Fehm
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): OT1-10-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-OT1-10-01
Published: 15 February 2019
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Journal Articles

Abstract OT2-07-01: DETECT V/CHEVENDO – Comparison of dual HER2-targeted therapy with trastuzumab plus pertuzumab in combination with chemo- or endocrine therapy in addition with CDK4/6 inhibition in patients with HER2-positive and hormone-receptor positive metastatic breast cancer

S Krause, T Friedl, T Fehm, T Romashova, PA Fasching, A Schneeweiss, V Müller, F-A Taran, A Polasik, M Tzschaschel, A De Gregorio, F Meier-Stiegen, W Janni, J Huober
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): OT2-07-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-OT2-07-01
Published: 15 February 2019
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Journal Articles

Abstract OT1-11-02: PRAEGNANT - Real world evidence, translational research, big and smart data: A prospective academic translational research network for the optimization of the oncological health care quality in the adjuvant and advanced/ metastatic setting (NCT02338167)

V Müller, J Huober, B Volz, F Overkamp, H-C Kolberg, P Hadji, L Haeberle, J Ettl, AD Hartkopf, MP Lux, DI Lüftner, M Wallwiener, F-A Taran, MW Beckmann, E Belleville, P Wimberger, C Hielscher, M Geberth, J Lermann, A Abenhardt, C Kurbacher, R Wuerstlein, C Thomssen, M Untch, W Janni, TN Fehm, SY Brucker, D Wallwiener, A Schneeweiss, PA Fasching, H Tesch
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): OT1-11-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-OT1-11-02
Published: 15 February 2019
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Journal Articles

Abstract P2-08-10: Similarities between low hormone receptor positive and hormone receptor negative breast cancer: An analysis of 4366 patients from multicenter clinical trials

SL Villegas, B Lederer, M Untch, F Holms, H-U Ulmer, K Diebold, PA Fasching, K Weber, WD Schmitt, H Tesch, M Rezai, F Marmé, B Sinn, J Hackmann, A Schneeweiss, A Tannapfel, V Nekljudova, C Denkert, S Loibl
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P2-08-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P2-08-10
Published: 15 February 2019
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Journal Articles

Abstract P2-08-01: Factors predicting relapse in early breast cancer patients with a pathological complete response after neoadjuvant therapy – Results of a pooled analysis based on the GBG meta-database

J Huober, A Schneeweiss, J-U Blohmer, C Denkert, H Tesch, CA Hanusch, C Salat, K Rhiem, M Rezai, C Solbach, PA Fasching, C Jackisch, K Mehta, V Nekljudova, F Seither, G von Minckwitz, S Loibl, M Untch
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P2-08-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P2-08-01
Published: 15 February 2019
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Journal Articles

Abstract P3-10-01: Single-cell profiling identifies hypoxic carcinoma cells as source of an immunosuppressive VEGFA metagene

T Karn, C Denkert, BV Sinn, K Weber, V Nekljudova, A Rody, T Meissner, C Hatzis, A El-Balat, S Becker, C Solbach, M Untch, A Schneeweiss, G von Minckwitz, S Loibl, L Pusztai, U Holtrich
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P3-10-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P3-10-01
Published: 15 February 2019
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Journal Articles

Abstract P4-06-01: Immunomonitoring of triple negative breast cancer patients undergoing neoadjuvant therapy with durvalumab - Results from the prospectively randomized GeparNuevo trial

C Massa, A Schneeweiss, T Karn, CA Hanusch, J-U Blohmer, PA Fasching, C Jackisch, M van Mackelenbergh, F Marmé, V Müller, C Schem, E Stickeler, J Huober, KE Weber, M Untch, C Denkert, S Loibl, A Mueller, K Biehl, B Seliger
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P4-06-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P4-06-01
Published: 15 February 2019
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Journal Articles

Abstract P4-06-10: Immune related gene expression to explore immue escape in primary to metastatic breast cancer transition

C Fremd, N Halama, R Wirtz, I Zoernig, H-P Sinn, Z Varga, M Feisst, T Deutsch, F Schuetz, A Schneeweiss, D Jaeger, M Wallwiener
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P4-06-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P4-06-10
Published: 15 February 2019
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Journal Articles

Abstract PD2-07: mRNA signatures predict response to durvalumab therapy in triple negative breast cancer (TNBC)– Results of the translational biomarker programme of the neoadjuvant double-blind placebo controlled GeparNuevo trial

S Loibl, BV Sinn, T Karn, M Untch, D Treue, H-P Sinn, KE Weber, CA Hanusch, PA Fasching, J Huober, D-M Zahm, C Jackisch, J Thomalla, J-U Blohmer, F Marmé, F Klauschen, K Rhiem, B Felder, G von Minckwitz, N Burchardi, A Schneeweiss, C Denkert
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): PD2-07.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-PD2-07
Published: 15 February 2019
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Journal Articles

Abstract P6-17-37: Therapy landscape of patients with metastatic, HER2 positive breast cancer - Data from the real world breast cancer registry PRAEGNANT (NCT02338167)

MP Lux, AD Hartkopf, J Huober, B Volz, F-A Taran, F Overkamp, P Hadji, H Tesch, L Haeberle, J Ettl, DI Lueftner, M Wallwiener, V Müller, MW Beckmann, E Belleville, P Wimberger, C Hielscher, M Geberth, J Lermann, W Abenhardt, C Kurbacher, R Wuerstlein, C Thomssen, M Untch, PA Fasching, W Janni, TN Fehm, D Wallwiener, SY Brucker, A Schneeweiss, H-C Kolberg
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-17-37.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-17-37
Published: 15 February 2019
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Journal Articles

Abstract P6-18-08: Everolimus + exemestane for HR+ advanced breast cancer in routine clinical practice- Final results from the non-interventional trial, BRAWO

D Lüftner, F Schuetz, A Schneeweiss, E-M Grischke, W Bloch, T Decker, C Uleer, C Salat, F Förster, M Schmidt, C Mundhenke, H Tesch, C Jackisch, T Fischer, G Guderian, S Hanson, P Fasching
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-08
Published: 15 February 2019
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Journal Articles

Abstract P6-17-22: Progression free survival (PFS) and overall survival (OS) of patients treated with trastuzumab emtansine (T-DM1) after previous treatment with pertuzumab in patients with advanced breast cancer (NCT02338167)

A Schneeweiss, MP Lux, AD Hartkopf, B Volz, H-C Kolberg, P Hadji, H Tesch, L Haeberle, J Ettl, DI Lüftner, M Wallwiener, V Müller, MW Beckmann, E Belleville, P Wimberger, C Hielscher, M Geberth, J Lermann, W Abenhardt, C Kurbacher, R Wuerstlein, C Thomssen, M Untch, F Overkamp, J Huober, F-A Taran, W Janni, D Wallwiener, SY Brucker, PA Fasching, TN Fehm
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-17-22.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-17-22
Published: 15 February 2019
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Journal Articles

Abstract PD5-05: Pre-therapeutic PD-L1 expression and dynamics of Ki-67 and gene expression during neoadjuvant immune-checkpoint blockade and chemotherapy to predict response within the GeparNuevo trial

BV Sinn, S Loibl, T Karn, M Untch, CA Kunze, KE Weber, D Treue, K Wagner, CA Hanusch, F Klauschen, PA Fasching, J Huober, D-M Zahm, C Jackisch, J Thomalla, J-U Blohmer, M van Mackelenbergh, K Rhiem, B Felder, G von Minckwitz, N Burchardi, A Schneeweiss, C Denkert
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): PD5-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-PD5-05
Published: 15 February 2019
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Journal Articles

Abstract GS5-03: Lifestyle Intervention and Effect on Disease-free Survival in Early Breast Cancer Pts: Interim Analysis from the Randomized SUCCESS C Study

W Janni, BK Rack, TW Friedl, V Müller, R Lorenz, M Rezai, H Tesch, G Heinrich, U Andergassen, N Harbeck, F Schochter, A De Gregorio, M Tzschaschel, J Huober, P Hepp, TN Fehm, A Schneeweiss, W Lichtenegger, J Blohmer, D Hauner, MW Beckmann, L Häberle, PA Fasching, H Hauner
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): GS5-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-GS5-03
Published: 15 February 2019
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Journal Articles

Abstract GS1-04: IMpassion130: Efficacy in immune biomarker subgroups from the global, randomized, double-blind, placebo-controlled, phase III study of atezolizumab + nab-paclitaxel in patients with treatment-naïve, locally advanced or metastatic triple-negative breast cancer

LA Emens, S Loi, HS Rugo, A Schneeweiss, V Diéras, H Iwata, CH Barrios, M Nechaeva, L Molinero, A Nguyen Duc, R Funke, SY Chui, A Husain, EP Winer, S Adams, P Schmid
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): GS1-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-GS1-04
Published: 15 February 2019
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Journal Articles

Abstract GS1-10: Phase III study of trastuzumab emtansine (T-DM1) vs trastuzumab as adjuvant therapy in patients with HER2-positive early breast cancer with residual invasive disease after neoadjuvant chemotherapy and HER2-targeted therapy including trastuzumab: Primary results from KATHERINE

CE Geyer, Jr., C-S Huang, MS Mano, S Loibl, EP Mamounas, M Untch, N Wolmark, P Rastogi, HH Fischer, A Redondo, C Jackisch, W Jacot, AK Conlin, A Schneeweiss, IL Wapnir, PA Fasching, MP DiGiovanna, P Wuelfing, C Arce-Salinas, JP Crown, Z Shao, E Rota Caremoli, H Wu, LH Lam, D Tesarowski, M Smitt, H Douthwaite, SM Singel, G von Minckwitz
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): GS1-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-GS1-10
Published: 15 February 2019
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Journal Articles

Abstract P6-13-01: Withdrawn

WJ Janni, N Harbeck, B Rack, O Gluz, A Schneeweiss, R Kates, T Fehm, H Kreipe, S Kümmel, R Würstlein, A Hartkopf, M Clemens, T Reimer, T Friedl, L Häberle, P Fasching, U Nitz
Journal: Cancer Research
Cancer Res (2018) 78 (4_Supplement): P6-13-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS17-P6-13-01
Published: 15 February 2018
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Abstract P6-15-03: Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials

G von Waldenfels, S Loibl, J Furlanetto, M Anna, B Lederer, C Denkert, C Hanusch, J Huober, C Jackisch, S Kümmel, G von Minckwitz, A Schneeweiss, M Untch, K Rhiem, PA Fasching, JU Blohmer
Journal: Cancer Research
Cancer Res (2018) 78 (4_Supplement): P6-15-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS17-P6-15-03
Published: 15 February 2018
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Journal Articles

Abstract PD7-09: Changes in hormone levels (E2, FSH, AMH) and fertility of young women treated with neoadjuvant chemotherapy (CT) for early breast cancer (EBC)

J Furlanetto, C Thode, J Huober, C Denkert, M Bassy, C Hanusch, C Jackisch, S Kümmel, A Schneeweiss, M Untch, PA Fasching, T Karn, F Marmé, M van Mackelenbergh, V Müller, C Schem, G von Minckwitz, D Strik, V Nekljudova, S Loibl
Journal: Cancer Research
Cancer Res (2018) 78 (4_Supplement): PD7-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS17-PD7-09
Published: 15 February 2018
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