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Journal Articles

Abstract SP012: Convergent evolution of resistance pathways during early stage breast cancer treatment with combination cell cycle (CDK) and endocrine signaling inhibitors

JI Griffiths, J Chen, PA Cosgrove, A O'Dea, P Sharma, CX Ma, M Trivedi, K Kalinsky, KB Wisinski, R O'Reagan, I Makhoul, LM Spring, A Bardia, FR Adler, AL Cohen, JT Chang, QJ Khan, AH Bild
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): SP012.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-SP12
Published: 15 February 2021
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Journal Articles

Abstract GS2-03: Pathological complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and mortality, stratified by breast cancer subtypes and adjuvant chemotherapy usage: Individual patient-level meta-analyses of over 27,000 patients

LM Spring, G Fell, A Arfe, L Trippa, R Greenup, K Reynolds, BL Smith, B Moy, SJ Isakoff, G Parmigiani, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): GS2-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-GS2-03
Published: 15 February 2019
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Journal Articles

Abstract OT3-04-03: KEYNOTE-756: A randomized, double-blind, phase III study of pembrolizumab versus placebo in combination with neoadjuvant chemotherapy and adjuvant endocrine therapy for high-risk early-stage ER+/HER2– breast cancer

F Cardoso, A Bardia, F Andre, DW Cescon, H McArthur, M Telli, S Loi, J Cortés, P Schmid, N Harbeck, C Denkert, C Jackisch, L Jia, K Tryfonidis, V Karantza
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): OT3-04-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-OT3-04-03
Published: 15 February 2019
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Journal Articles

Abstract P1-15-01: Withdrawn

O Metzger Filho, M Janiszewska, H Guo, D Yardley, I Mayer, L Spring, C Arteaga, E Wrabel, M DeMeo, R Freedman, S Tolaney, A Waks, A Bardia, H Parsons, A Partridge, E Mayer, T King, K Polyak, G Viale, E Winer, I Krop
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P1-15-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P1-15-01
Published: 15 February 2019
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Journal Articles

Abstract P2-14-19: Surgical and long-term outcomes of patients receiving neoadjuvant pertuzumab-containing regimens for HER2-positive localized breast cancer

SA Haddad, LM Spring, RB Jimenez, N Vidula, A Comander, JA Shin, SB Coopey, MA Gadd, KS Hughes, A Taghian, BL Smith, SJ Isakoff, B Moy, A Bardia, MC Specht
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P2-14-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P2-14-19
Published: 15 February 2019
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Journal Articles

Abstract P2-11-01: Safety and efficacy of sacituzumab govitecan (anti-Trop-2-SN-38 antibody-drug conjugate) as ≥3rd-line therapeutic option for treatment-refractory HER2-negative metastatic breast cancer (HER2Neg mBC)

K Kalinsky, SJ Isakoff, SM Tolaney, D Juric, IA Mayer, LT Vahdat, JR Diamond, J O'Shaughnessy, RL Moroose, AD Santin, NC Shah, V Abramson, DM Goldenberg, RM Sharkey, SA Washkowitz, WA Wegener, R Iannone, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P2-11-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P2-11-01
Published: 15 February 2019
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Journal Articles

Abstract P5-11-01: Phamacodynamic and circulating tumor DNA evaluation in a phase I study of GDC-0927, a selective estrogen receptor antagonist/ degrader (SERD)

JM Spoerke, A Daemen, C-W Chang, J Giltnane, C Metcalfe, MN Dickler, A Bardia, JA Perez Fidalgo, IA Mayer, V Boni, EP Winer, EP Hamilton, M Bellet, A Urruticoechea, A Gonzalez Martin, J Cortes, M Martin, M Gates, S Cheeti, J Fredrickson, X Wang, LS Friedman, L Liu, R Li, IT Chan, L Mueller, S Milan, J Lauchle, EW Humke, MR Lackner
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P5-11-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P5-11-01
Published: 15 February 2019
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Journal Articles

Abstract P4-01-06: Comparison of tumor genotyping and cell-free circulating tumor DNA sequencing in metastatic breast cancer patients and their utility in the selection of matched therapy

N Vidula, D Juric, A Niemierko, L Spring, B Moy, G Malvarosa, M Yuen, K Habin, J Shin, J Peppercorn, S Isakoff, L Ellisen, AJ Iafrate, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P4-01-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P4-01-06
Published: 15 February 2019
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Journal Articles

Abstract P3-14-02: Upper extremity edema in the at-risk arm among patients receiving PI3K/mTOR/CDK4/6 inhibitors for metastatic breast cancer

KM Daniell, A Bardia, F Sun, CL Brunelle, TC Gillespie, HE Sayegh, GE Naoum, SJ Isakoff, D Juric, AG Taghian
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P3-14-02.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P3-14-02
Published: 15 February 2019
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Journal Articles

Abstract P4-08-08: Genomic progression, detected by circulating tumor DNA (ctDNA) sequencing, as an early predictor of disease progression in metastatic breast cancer (MBC)

M Velimirovic, D Juric, A Niemierko, LM Spring, N Vidula, G Malvarosa, M Yuen, B Moy, SJ Isakoff, LW Ellisen, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P4-08-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P4-08-08
Published: 15 February 2019
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Journal Articles

Abstract PD2-08: Ribociclib with endocrine therapy for premenopausal patients with hormone receptor-positive, HER2-negative advanced breast cancer: Biomarker analyses from the phase III randomized MONALEESA-7 trial

A Bardia, M Colleoni, S Campos-Gomez, KH Jung, P Wheatley-Price, S Kümmel, V Srimuninnimit, D Taylor, Y-H Im, G Hughes, I Diaz-Padilla, M Miller, F Su, D Tripathy
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): PD2-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-PD2-08
Published: 15 February 2019
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Journal Articles

Abstract P6-18-15: Ribociclib + endocrine therapy in hormone receptor-positive, HER2-negative advanced breast cancer: A pooled safety analysis

HA Burris, A Chan, S-A Im, S Chia, D Tripathy, FJ Esteva, M Campone, A Bardia, O Kong, W Bao, I Diaz-Padilla, K Rodriguez Lorenc, DA Yardley
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-15.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-15
Published: 15 February 2019
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Journal Articles

Abstract P6-18-06: Ribociclib treatment benefit in patients with advanced breast cancer with ≥1 dose reduction: Data from the MONALEESA-2, -3, and -7 trials

JT Beck, P Neven, J Sohn, A Chan, GS Sonke, T Bachelot, S Campos-Gomez, M Martin, A Bardia, J Alam, M Miller, I Diaz-Padilla, O Kong, L Hart
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-06
Published: 15 February 2019
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Journal Articles

Abstract P6-18-04: Ribociclib with a non-steroidal aromatase inhibitor and goserelin in premenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer: MONALEESA-7 age subgroup analysis

D Tripathy, S Campos-Gomez, Y-S Lu, F Franke, A Bardia, P Wheatley-Price, FM Cruz, R Hegg, F Cardoso, A Gaur, O Kong, I Diaz-Padilla, M Miller, S Hurvitz
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-04
Published: 15 February 2019
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Journal Articles

Abstract P6-17-35: Withdrawn

EP Hamilton, M Barve, A Bardia, M Beeram, WJ Edenfield, A Noonan, A Tolcher, J Bendell, R Mosher, J Xu, E Hailman, H Burris III, HH Soliman
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-17-35.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-17-35
Published: 15 February 2019
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Journal Articles

Abstract P6-18-10: A phase 1b/2 study of ribociclib plus trastuzumab for the treatment of advanced, treatment-refractory HER2-positive breast cancer

S Goel, L Spring, R Rees, C Andrews, RK Tahara, EL Mayer, A Bardia, EP Winer, SM Tolaney
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-10.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-10
Published: 15 February 2019
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Journal Articles

Abstract P6-18-14: Patient-reported outcomes with ribociclib-based therapy in hormone receptor-positive, HER2-negative advanced breast cancer: results from the phase III MONALEESA-2, -3, and -7 trials

JT Beck, P Neven, FJ Esteva, A Bardia, N Harbeck, S Hurvitz, J O'Shaughnessy, S Verma, B Lanoue, J Alam, O Kong, D Chandiwana, S Chia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-14.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-14
Published: 15 February 2019
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Journal Articles

Abstract P6-18-39: Abemaciclib after prior palbociclib exposure in patients with metastatic hormone-receptor positive (HR+)/HER2- breast cancer

SA Wander, LM Spring, CR Stein, M Yuen, M Zangardi, J O'Shaughnessy, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): P6-18-39.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-P6-18-39
Published: 15 February 2019
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Journal Articles

Abstract PD9-06: Paired pre- and post-treatment DNA sequencing identifies genomic alterations mediating clinical resistance to CDK 4/6 inhibitors in patients with metastatic breast cancer

LM Spring, S Haddad, G Malvarosa, N Vidula, D Juric, AJ Iafrate, LW Ellisen, B Moy, SJ Isakoff, A Bardia
Journal: Cancer Research
Cancer Res (2019) 79 (4_Supplement): PD9-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS18-PD9-06
Published: 15 February 2019
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Journal Articles

Abstract PD1-13: Somatic BRCA mutation detection by circulating tumor DNA analysis in patients with metastatic breast cancer: Incidence and association with tumor genotyping results, germline BRCA mutation status, and clinical outcomes

N Vidula, SJ Isakoff, A Niemierko, G Malvarosa, H Park, E Abraham, L Spring, J Peppercorn, B Moy, LW Ellisen, D Juric, A Bardia
Journal: Cancer Research
Cancer Res (2018) 78 (4_Supplement): PD1-13.
DOI: https://doi.org/10.1158/1538-7445.SABCS17-PD1-13
Published: 15 February 2018
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