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Álvaro S. Padrón
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Journal Articles

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality

Anand V.R. Kornepati, Jacob T. Boyd, Clare E. Murray, Julia Saifetiarova, Bárbara de la Peña Avalos, Cody M. Rogers, Haiyan Bai, Alvaro S. Padron, Yiji Liao, Carlos Ontiveros, Robert S. Svatek, Robert Hromas, Rong Li, Yanfen Hu, Jose R. Conejo-Garcia, Ratna K. Vadlamudi, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2022) 82 (11): 2156–2170.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-2076
Published: 06 June 2022
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Journal Articles

CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade

Justin M. Drerup, Yilun Deng, Sri Lakshmi Pandeswara, Álvaro S. Padrón, Ryan M. Reyes, Xinyue Zhang, Jenny Mendez, Aijie Liu, Curtis A. Clark, Wanjiao Chen, José R. Conejo-Garcia, Vincent Hurez, Harshita Gupta, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2020) 80 (22): 5063–5075.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0002
Published: 13 November 2020
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Includes: Supplementary data
Journal Articles

Abstract 1608: CD122-selective IL-2/anti-IL-2 complexes reduce regulatory T cell function and promote CD8+ T cell polyfunctionality for durable ovarian cancer immunotherapy

Justin M. Drerup, Sri Lakshmi Pandeswara, Aijie Liu, Curtis A. Clark, Alvaro S. Padron, Wanjiao Chen, Vincent Hurez, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1608.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1608
Published: 01 July 2017
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Journal Articles

Abstract 5649: Cell-intrinsic PD-L1 directs tumor initiating cell fate and rapamycin and interferon-γ response

Harshita B. Gupta, Curtis A. Clark, Bin Yuan, Gangadhara Sareddy, Srilakshmi Pandeswara, Alvaro S. Padron, Vincent Hurez, Jose-Conejo Garcia, Ratna Vadlamudi, Rong Li, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5649.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5649
Published: 01 July 2017
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