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### Scope

Cancer Research publishes original studies, reviews, and opinion pieces offering significance and broad impact to a diverse audience. Cancer Research seeks manuscripts that offer pathobiological and translational impact to inform the personal, clinical, and societal problems posed by cancer. The main scope of the journal is captured in its primary subsections:

### General Criteria for Studies Considered by the Journal

• Findings that have not been previously published in another tumor model.
• Studies performed in multiple cell lines.
• Conclusions that are not representative of incremental findings.
• Studies that include a clearly written title and abstract that communicate the study's impact of significance to non-experts.
• An incisive rationale that could interest a broad audience.
• Manuscripts containing in vivo data. Although in vivo data is not required, studies containing this data are preferred.
• A potentially generalizable, broad impact conclusion.
• Studies that describe RNA interference (RNAi) must contain one non-specific control and two specific siRNAs for each knockdown target of interest. Additional data is required that demonstrates knockdown achievement at the level of protein expression (not just mRNA).

### Manuscript Submission<

Cancer Research welcomes submissions of primary research, review and commentary article types as well as letters to the editor. For descriptions and length requirements of the article types available to submitting authors, see the journal’s Categories of Articles.

The AACR Journals all use a similar Editorial Process and adhere to the same overarching Editorial Policies, both of which are detailed in the Information for Authors. These instructions contain important guidelines on authorship, publishing ethics, availability of materials and data, and data analysis and reporting. Authors should be familiar with these instructions prior to submitting their work to the journal.

Manuscripts are stringently reviewed for high standards of scientific merit, and only those that report results of novel, timely, and broadly-significant research are accepted for publication.

Submit your article to Cancer Research

### Journal Metrics

Cancer Research is the most frequently cited cancer journal in the world. For detailed metrics about Cancer Research and the other AACR journals see AACR Journals Metrics.

### Editors and Editorial Board

Editorial oversight of Cancer Research and decisions on manuscripts submitted to the journal are the responsibility of the Editorial Boardwith support from journal staff. See Editorial Board for more information.

Material published in Cancer Research is covered and protected by copyright. Authors who wish to publish in the journal must formally transfer copyright to the AACR, but are granted considerable reuse rights. The final typeset version of every published article is rendered freely accessible 12 months after publication. Authors who prefer for their article to be immediately freely accessible online may make this selection by paying an additional fee through the AACR AuthorChoice option. In addition, the AACR assists authors in satisfying major funder Open Access archiving mandates by depositing the accepted author version of their article in a designated public repository. For additional details about all these topics, see Copyright, Permissions and Access.

### Publication Fees

To defray publication costs and to support other AACR programs, publication in Cancer Research involves the payment of a fixed publication fee and an additional fee for any color figures. If no financial support exists, authors may apply for a waiver of the fixed publication fee at the time of submission. See Publication Fees for further details.

### Journal Information

Cancer Research (CR) (Print ISSN: 0008-5472; Online ISSN: 1538-7445) is published twice a month, one volume/year, by the American Association for Cancer Research, Inc. (AACR).

Cancer Research is abstracted and/or indexed in BIOSIS Previews (R) Database, MEDLINE, Current Contents/Life Sciences, Current Contents/Clinical Medicine, Science Citation Index, Scopus, and Web of Science.

The journal is printed on paper that meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper).

### Back Issues and Single Issue Sales

Subject to availability, single or back issues of Cancer Research may be purchased for $60 per copy in the U.S. or$65 per copy outside the U.S. For more information, contact:

AACR Publications Sales & Marketing Department
American Association for Cancer Research
615 Chestnut Street, 17th Floor