The image depicts the Battle of Chibi (meaning ‘Red Cliff’ in Chinese), one of the most famous battles in Chinese history. In the Battle of Chibi (208 AD), two groups joined forces to halt the advance of strong enemies. Similarly, Sun and colleagues target MYC-driven cancer with the combined inactivation of CTPS1 and ATR in this issue. The image depicts the two forces (in the shape of arrowheads) joining the battle (depicted by the fire). For details, see the article by Sun and colleagues on page 1013. (Concept, Ji-Long Liu; Illustration, Jia Du.)