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Issues

Cancer Research

Table of Contents


Breaking Insights

Review

Cancer Research Landmarks

Cancer Research Highlights

Controversy and Consensus

Genome and Epigenome

This study identifies race-specific genetic associations with breast cancer risk of recurrence scores and suggests mediation of these associations by PAM50 subtype and expression, with implications for clinical interpretation of these scores.

CRISPR-mediated DNA damage enriches for cells with escape mutations in a core CRISPR–p53 interactome, which can be suppressed by transient inhibition of p53.

Molecular Cell Biology

Tumor Biology and Immunology

Translational Science

A novel but widespread transcriptional mechanism by which homologous recombination deficiency arises independently of BRCA1/2 mutations can be utilized as a companion diagnostic for PARP inhibitors.

Acknowledgment to Reviewers

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