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Volume 80, Issue 14

15 July 2020

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Cover Image

Cover Image

Chemotherapy causes inflammatory changes, such as IL8 upregulation in tumors, inducing a drug transporter, ABCB1, expression in tumor endothelial cells. This causes drug resistance in tumor blood vessels. It is possible that tumor endothelial cells can survive during chemotherapy and keep providing a gateway for cancer metastasis. Targeting ABCB1 in tumor endothelial cells, or IL8 inhibition, represents a novel strategy to overcome cancer drug resistance. For details, see article by Kikuchi and colleagues on page 2996.
Table of Contents
Editorial Board

ISSN 0008-5472

EISSN 1538-7445

Issue Sections

Breaking Insights
Review
Cancer Research Highlights
Controversy and Consensus
Molecular Cell Biology
Tumor Biology and Immunology
Translational Science

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.