Issues
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TGFβ is involved in various biological processes including epithelial-mesenchymal transition (EMT). A novel long noncoding RNA ELIT-1, which is induced by TGFβ, binds to Smad3 and facilitates recruitment of the complex to target genes of the TGFβ-Smad3 pathway. Using immunofluorescence, it was found that depletion of ELIT-1 inhibited perturbation of E-cadherin localization and actin stress fiber formation induced by TGFβ, suggesting that ELIT-1 participates in progression of EMT. For details, see article by Sakai and colleagues on page 2821. - PDF Icon PDF LinkTable of Contents
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Cancer Research
Table of Contents
Breaking Insights
Obituary
Review
Cancer Research Highlights
Priority Report
Molecular Cell Biology
Tumor Biology and Immunology
The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State
Translational Science
Activation of the Unfolded Protein Response via Inhibition of Protein Disulfide Isomerase Decreases the Capacity for DNA Repair to Sensitize Glioblastoma to Radiotherapy
Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy
Convergence and Technologies
MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment
Population and Prevention Science
Analysis of the CDKN2A Gene in FAMMM Syndrome Families Reveals Early Age of Onset for Additional Syndromic Cancers
Resource Report
Correction
Retraction
Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling
Journal Archive
Cancer Research
(1941-Present; volumes 1-current)Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)
The American Journal of Cancer
(1931-1940; volumes 15-40)Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)
The Journal of Cancer Research
(1916-1930); volumes 1-14)Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)
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