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Volume 78, Issue 20
15 October 2018
Cancer Research Cover Image for Volume 78, Issue 20
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  • Cover Image

    Cover Image

    Issue cover image
    The cover art is based on a microscopic May-Grunwald-Giemsa staining of untreated control primary human CD34+ AML blasts that were spotted on a glass slide and formed a heart-shaped structure. The image was taken with a Leica DM 3000 or Leica DM IL microscope with a Leica DFC420C camera (Leica Geosystems B.V.). This picture has been artistically modified in Photoshop to create an embracing colorful projection of the AML blasts. For details, see article by Kampen and colleagues on page 5940.
  • PDF Icon PDF LinkTable of Contents
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ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Breaking Insights

Highlights from Recent Cancer Literature
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Review

Promoting Scientist–Advocate Collaborations in Cancer Research: Why and How
Jeannine M. Salamone; Wanda Lucas; Shelley B. Brundage; Jamie N. Holloway; Sherri M. Stahl; Nora E. Carbine; Margery London; Naomi Greenwood; Rosa Goyes; Deborah Charles Chisholm; Erin Price; Roberta Carlin; Susan Winarsky; Kirsten B. Baker; Julia Maues; Ayesha N. Shajahan-Haq
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Cancer Research Highlights

Choosing the Best Chemotherapy Agent to Boost Immune Checkpoint Inhibition Activity
Marina Chiara Garassino; Valter Torri; Mario Paolo Colombo; Antonio Sica
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Priority Report

Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer
Lanbo Xiao; Jean C. Tien; Josh Vo; Mengyao Tan; Abhijit Parolia; Yajia Zhang; Lisha Wang; Yuanyuan Qiao; Sudhanshu Shukla; Xiaoju Wang; Heng Zheng; Fengyun Su; Xiaojun Jing; Esther Luo; Andrew Delekta; Kristin M. Juckette; Alice Xu; Xuhong Cao; Ajjai S. Alva; Youngsoo Kim; A. Robert MacLeod; Arul M. Chinnaiyan
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Genome and Epigenome

Featured Image
A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma
Stefania Oliveto; Roberta Alfieri; Annarita Miluzio; Alessandra Scagliola; Raissa S. Secli; Pierluigi Gasparini; Stefano Grosso; Luciano Cascione; Luciano Mutti; Stefano Biffo
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Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells
Minmin Liu; Stacey L. Thomas; Ashley K. DeWitt; Wanding Zhou; Zachary B. Madaj; Hitoshi Ohtani; Stephen B. Baylin; Gangning Liang; Peter A. Jones
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Molecular Cell Biology

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MYBL2 Supports DNA Double Strand Break Repair in Hematopoietic Stem Cells
Rachel Bayley; Daniel Blakemore; Laila Cancian; Stephanie Dumon; Giacomo Volpe; Carl Ward; Ruba Almaghrabi; Jidnyasa Gujar; Natasha Reeve; Manoj Raghavan; Martin R. Higgs; Grant S. Stewart; Eva Petermann; Paloma García
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Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer
Fang-Lin Zhang; Jin-Ling Cao; Hong-Yan Xie; Rui Sun; Li-Feng Yang; Zhi-Ming Shao; Da-Qiang Li
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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia
Valentina Minieri; Marco De Dominici; Patrizia Porazzi; Samanta A. Mariani; Orietta Spinelli; Alessandro Rambaldi; Luke F. Peterson; Pierluigi Porcu; Marja T. Nevalainen; Bruno Calabretta
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Amplification of Glyceronephosphate O-Acyltransferase and Recruitment of USP30 Stabilize DRP1 to Promote Hepatocarcinogenesis
Li Gu; Yahui Zhu; Xi Lin; Yajun Li; Kaisa Cui; Edward V. Prochownik; Youjun Li
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Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem–like Cells
Jenny Högström; Sarika Heino; Pauliina Kallio; Marianne Lähde; Veli-Matti Leppänen; Diego Balboa; Zoltán Wiener; Kari Alitalo
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Author Choice
A Mutant p53-Dependent Embryonic Stem Cell Gene Signature Is Associated with Augmented Tumorigenesis of Stem Cells
Gabriela Koifman; Yoav Shetzer; Shay Eizenberger; Hilla Solomon; Ron Rotkopf; Alina Molchadsky; Giuseppe Lonetto; Naomi Goldfinger; Varda Rotter
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CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder
Xin Chen; Jia-Xing Zhang; Jun-Hang Luo; Song Wu; Gang-Jun Yuan; Ning-Fang Ma; Yong Feng; Mu-Yan Cai; Ri-Xin Chen; Jun Lu; Li-Juan Jiang; Jie-Wei Chen; Xiao-Han Jin; Hai-Liang Liu; Wei Chen; Xin-Yuan Guan; Tie-Bang Kang; Fang-Jian Zhou; Dan Xie
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PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer
Martin L. Read; Bhavika Modasia; Alice Fletcher; Rebecca J. Thompson; Katie Brookes; Peter C. Rae; Hannah R. Nieto; Vikki L. Poole; Sally Roberts; Moray J. Campbell; Kristien Boelaert; Andrew S. Turnell; Vicki E. Smith; Hisham Mehanna; Christopher J. McCabe
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EGR1-Mediated Transcription of lncRNA-HNF1A-AS1 Promotes Cell-Cycle Progression in Gastric Cancer
Hai-Ting Liu; Sen Liu; Lei Liu; Ran-Ran Ma; Peng Gao
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Tumor Biology and Immunology

Featured Image
Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner
Carlos W. Wanderley; David F. Colón; João Paulo M. Luiz; Francisco F. Oliveira; Paula R. Viacava; Caio A. Leite; Janaina A. Pereira; Camila M. Silva; Cassia R. Silva; Rangel L. Silva; Cesar A. Speck-Hernandez; José M. Mota; José C. Alves-Filho; Roberto C. Lima-Junior; Thiago M. Cunha; Fernando Q. Cunha
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Author Choice
Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype
Kaveh M. Goudarzi; Jaime A. Espinoza; Min Guo; Jiri Bartek; Monica Nistér; Mikael S. Lindström; Daniel Hägerstrand
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Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Björn Hiller; Anja Hoppe; Christa Haase; Christina Hiller; Nadja Schubert; Werner Müller; Martin A.M. Reijns; Andrew P. Jackson; Thomas A. Kunkel; Jörg Wenzel; Rayk Behrendt; Axel Roers
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Schwann Cells Augment Cell Spreading and Metastasis of Lung Cancer
Yan Zhou; Galina V. Shurin; Hua Zhong; Yuri L. Bunimovich; Baohui Han; Michael R. Shurin
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Translational Science

VEGFC Antibody Therapy Drives Differentiation of AML
Kim R. Kampen; Frank J.G. Scherpen; Hasan Mahmud; Arja ter Elst; André B. Mulder; Victor Guryev; Han J.M.P. Verhagen; Kim De Keersmaecker; Linda Smit; Steven M. Kornblau; Eveline S.J.M. De Bont
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A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors
Nannan Ning; Yamei Yu; Min Wu; Ruihong Zhang; Ting Zhang; Changjun Zhu; Lei Huang; Cai-Hong Yun; Cyril H. Benes; Jianming Zhang; Xianming Deng; Qiang Chen; Ruibao Ren
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Author Choice
Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma
Noémie Braekeveldt; Kristoffer von Stedingk; Susanne Fransson; Angela Martinez-Monleon; David Lindgren; Håkan Axelson; Fredrik Levander; Jakob Willforss; Karin Hansson; Ingrid Øra; Torbjörn Backman; Anna Börjesson; Siv Beckman; Javanshir Esfandyari; Ana P. Berbegall; Rosa Noguera; Jenny Karlsson; Jan Koster; Tommy Martinsson; David Gisselsson; Sven Påhlman; Daniel Bexell
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Author Choice
Spatially Resolved Transcriptomics Enables Dissection of Genetic Heterogeneity in Stage III Cutaneous Malignant Melanoma
Kim Thrane; Hanna Eriksson; Jonas Maaskola; Johan Hansson; Joakim Lundeberg
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Convergence and Technologies

Featured Image
Author Choice
Oxygen-Enhanced and Dynamic Contrast-Enhanced Optoacoustic Tomography Provide Surrogate Biomarkers of Tumor Vascular Function, Hypoxia, and Necrosis
Michal R. Tomaszewski; Marcel Gehrung; James Joseph; Isabel Quiros-Gonzalez; Jonathan A. Disselhorst; Sarah E. Bohndiek
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In Vivo Estimation of Oncolytic Virus Populations within Tumors
Mi-Yeon Jung; Chetan P. Offord; Matthew K. Ennis; Iris Kemler; Claudia Neuhauser; David Dingli
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Clinical Proteomics of Breast Cancer Reveals a Novel Layer of Breast Cancer Classification
Gali Yanovich; Hadar Agmon; Michal Harel; Amir Sonnenblick; Tamar Peretz; Tamar Geiger
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Population and Prevention Science

Pooled Analysis of Nine Cohorts Reveals Breast Cancer Risk Factors by Tumor Molecular Subtype
Mia M. Gaudet; Gretchen L. Gierach; Brian D. Carter; Juhua Luo; Roger L. Milne; Elisabete Weiderpass; Graham G. Giles; Rulla M. Tamimi; A. Heather Eliassen; Bernard Rosner; Alicja Wolk; Hans-Olov Adami; Karen L. Margolis; Susan M. Gapstur; Montserrat Garcia-Closas; Louise A. Brinton
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Letter to the Editor

Innervation of the Tumor Microenvironment–Letter
Mark R. Goldstein; Luca Mascitelli
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Corrections

Correction: MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1
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Correction: RSF1 Is a Positive Regulator of NFκB-induced Gene Expression Required for Ovarian Cancer Chemoresistance
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Correction: Absence of the Full-Length Breast Cancer–Associated Gene-1 Leads to Increased Expression of Insulin-Like Growth Factor Signaling Axis Members
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Correction: Telomerase-dependent Virotherapy Overcomes Resistance of Hepatocellular Carcinomas against Chemotherapy and Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand by Elimination of Mcl-1
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Correction: A Telomerase-dependent Conditionally Replicating Adenovirus for Selective Treatment of Cancer
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Retraction

Retraction: Down-regulation of Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 Expression by Soy Isoflavones Enhances Prostate Cancer Radiotherapy In vitro and In vivo
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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