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Volume 78, Issue 15
1 August 2018
Cancer Research Cover Image for Volume 78, Issue 15
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  • Cover Image

    Cover Image

    Issue cover image
    Twist1 regulates Cul2 pre-mRNA to alternatively spliced circRNA. The circRNA absorbs miRNAs targeting vimentin, thereby improving the expression of vimentin and driving epithelial-mesenchymal transition mediated by Twist1 in hepatocellular carcinoma. The image shows the epithelial phenotype of hepatocellular carcinoma cells released from the Twist1 pathway. For details, see article by Meng and colleagues on page 4150.
  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Breaking Insights

Highlights from Recent Cancer Literature
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Editorial

The Half-Lives of Facts, Paradigm Shifts, and Reproducibility in Cancer Research
Chi Van Dang
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Review

CRISPR–Cas13 Precision Transcriptome Engineering in Cancer
Javier T. Granados-Riveron; Guillermo Aquino-Jarquin
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Genome and Epigenome

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The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
Simon Weissmann; Paul A. Cloos; Simone Sidoli; Ole N. Jensen; Steven Pollard; Kristian Helin
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TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer
Charly Ryan Good; Shoghag Panjarian; Andrew D. Kelly; Jozef Madzo; Bela Patel; Jaroslav Jelinek; Jean-Pierre J. Issa
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Oncogenic Properties of NEAT1 in Prostate Cancer Cells Depend on the CDC5L–AGRN Transcriptional Regulation Circuit
Xin Li; Xianteng Wang; Wanlu Song; Hui Xu; Rongyao Huang; Yuting Wang; Wenwei Zhao; Zhengtao Xiao; Xuerui Yang
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Molecular Cell Biology

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Author Choice
Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma
Jing Meng; Shuang Chen; Jing-Xia Han; Baoxin Qian; Xiao-Rui Wang; Wei-Long Zhong; Yuan Qin; Heng Zhang; Wan-Feng Gao; Yue-Yang Lei; Wei Yang; Lan Yang; Chao Zhang; Hui-Juan Liu; Yan-Rong Liu; Hong-Gang Zhou; Tao Sun; Cheng Yang
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Long Noncoding RNA AB074169 Inhibits Cell Proliferation via Modulation of KHSRP-Mediated CDKN1a Expression in Papillary Thyroid Carcinoma
Qiheng Gou; Linbo Gao; Xinwen Nie; Wenchen Pu; Jingqiang Zhu; Yichao Wang; Xuesha Liu; Shuangyan Tan; Jian-Kang Zhou; Yanqiu Gong; Juan He; Ke Wu; Yuxin Xie; Wanjun Zhao; Lunzhi Dai; Lunxu Liu; Rong Xiang; Yu-Quan Wei; Lin Zhang; Yong Peng
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miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway
Mohamed Salem; Jacob A. O'Brien; Stefanie Bernaudo; Heba Shawer; Gang Ye; Jelena Brkić; Asma Amleh; Barbara C. Vanderhyden; Basel Refky; Burton B. Yang; Sergey N. Krylov; Chun Peng
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Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
Haiquan Lu; Linh Tran; Youngrok Park; Ivan Chen; Jie Lan; Yangyiran Xie; Gregg L. Semenza
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Hexavalent Chromium–Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair–Deficient Phenotype
Sandra S. Wise; Abou El-Makarim Aboueissa; Julieta Martino; John Pierce Wise, Sr.
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Author Choice
Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements
Jae Ho Seo; Ekta Agarwal; Kelly G. Bryant; M. Cecilia Caino; Eui Tae Kim; Andrew V. Kossenkov; Hsin-Yao Tang; Lucia R. Languino; Dmitry I. Gabrilovich; Andrew R. Cohen; David W. Speicher; Dario C. Altieri
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FGFR1-Activated Translation of WNT Pathway Components with Structured 5′ UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation
Tuan M. Nguyen; Elena B. Kabotyanski; Yongchao Dou; Lucas C. Reineke; Peng Zhang; Xiang H.-F. Zhang; Anna Malovannaya; Sung Yun Jung; Qianxing Mo; Kevin P. Roarty; Yiwen Chen; Bing Zhang; Joel R. Neilson; Richard E. Lloyd; Charles M. Perou; Matthew J. Ellis; Jeffrey M. Rosen
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Tumor Biology and Immunology

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Macrophages Promote Circulating Tumor Cell–Mediated Local Recurrence following Radiotherapy in Immunosuppressed Patients
Marjan Rafat; Todd A. Aguilera; Marta Vilalta; Laura L. Bronsart; Luis A. Soto; Rie von Eyben; Meghana A. Golla; Yasaman Ahrari; Stavros Melemenidis; Anosheh Afghahi; Melissa J. Jenkins; Allison W. Kurian; Kathleen C. Horst; Amato J. Giaccia; Edward E. Graves
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Author Choice
Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer
Valeria Quaranta; Carolyn Rainer; Sebastian R. Nielsen; Meirion L. Raymant; Muhammad S. Ahmed; Dannielle D. Engle; Arthur Taylor; Trish Murray; Fiona Campbell; Daniel H. Palmer; David A. Tuveson; Ainhoa Mielgo; Michael C. Schmid
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Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer
Lydia Meder; Philipp Schuldt; Martin Thelen; Anna Schmitt; Felix Dietlein; Sebastian Klein; Sven Borchmann; Kerstin Wennhold; Ignacija Vlasic; Sebastian Oberbeck; Richard Riedel; Alexandra Florin; Kristina Golfmann; Hans A. Schlößer; Margarete Odenthal; Reinhard Buettner; Juergen Wolf; Michael Hallek; Marco Herling; Michael von Bergwelt-Baildon; H. Christian Reinhardt; Roland T. Ullrich
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Radiotherapy and CD40 Activation Separately Augment Immunity to Checkpoint Blockade in Cancer
Andrew J. Rech; Hannah Dada; Jonathan J. Kotzin; Jorge Henao-Mejia; Andy J. Minn; Christina Twyman-Saint Victor; Robert H. Vonderheide
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Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment
Marie-Nicole Theodoraki; Saigopalakrishna Yerneni; Saumendra N. Sarkar; Brian Orr; Ravikumar Muthuswamy; Jamie Voyten; Francesmary Modugno; Weijian Jiang; Melissa Grimm; Per H. Basse; David L. Bartlett; Robert P. Edwards; Pawel Kalinski
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Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses
Kshipra Singh; Lori A. Coburn; Mohammad Asim; Daniel P. Barry; Margaret M. Allaman; Chanjuan Shi; M. Kay Washington; Paula B. Luis; Claus Schneider; Alberto G. Delgado; M. Blanca Piazuelo; John L. Cleveland; Alain P. Gobert; Keith T. Wilson
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Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis
Fei Xing; Yin Liu; Shih-Ying Wu; Kerui Wu; Sambad Sharma; Yin-Yuan Mo; Jiamei Feng; Stephanie Sanders; Guangxu Jin; Ravi Singh; Pierre-Alexandre Vidi; Abhishek Tyagi; Michael D. Chan; Jimmy Ruiz; Waldemar Debinski; Boris C. Pasche; Hui-Wen Lo; Linda J. Metheny-Barlow; Ralph B D'Agostino, Jr; Kounosuke Watabe
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Translational Science

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Author Choice
BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC
Brandon Leonard; Toni M. Brand; Rachel A. O'Keefe; Eliot D. Lee; Yan Zeng; Jacquelyn D. Kemmer; Hua Li; Jennifer R. Grandis; Neil E. Bhola
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Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance
Tirtha K. Das; Jessica Esernio; Ross L. Cagan
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Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma
Inan Olmez; Ying Zhang; Laryssa Manigat; Mouadh Benamar; Breanna Brenneman; Ichiro Nakano; Jakub Godlewski; Agnieszka Bronisz; Jeongwu Lee; Tarek Abbas; Roger Abounader; Benjamin Purow
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Author Choice
Licofelone Enhances the Efficacy of Paclitaxel in Ovarian Cancer by Reversing Drug Resistance and Tumor Stem-like Properties
Jeff Hirst; Harsh B. Pathak; Stephen Hyter; Ziyan Y. Pessetto; Thuc Ly; Stefan Graw; Devin C. Koestler; Adam J. Krieg; Katherine F. Roby; Andrew K. Godwin
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Specific Targeting of MTAP-Deleted Tumors with a Combination of 2′-Fluoroadenine and 5′-Methylthioadenosine
Baiqing Tang; Hyung-Ok Lee; Serim S. An; Kathy Q. Cai; Warren D. Kruger
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Convergence and Technologies

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Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines
Katarzyna Jastrzebski; Bram Thijssen; Roelof J.C. Kluin; Klaas de Lint; Ian J. Majewski; Roderick L. Beijersbergen; Lodewyk F.A. Wessels
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Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Lei Wang; Sara J. Felts; Virginia P. Van Keulen; Adam D. Scheid; Matthew S. Block; Svetomir N. Markovic; Larry R. Pease; Yuji Zhang
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TCIApathfinder: An R Client for the Cancer Imaging Archive REST API
Pamela Russell; Kelly Fountain; Dulcy Wolverton; Debashis Ghosh
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Population and Prevention Science

Cancer-Specific and General Nutritional Scores and Cancer Risk: Results from the Prospective NutriNet-Santé Cohort
Céline Lavalette; Moufidath Adjibade; Bernard Srour; Laury Sellem; Thibault Fiolet; Serge Hercberg; Paule Latino-Martel; Philippine Fassier; Mélanie Deschasaux; Emmanuelle Kesse-Guyot; Mathilde Touvier
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Projections in Breast and Lung Cancer Mortality among Women: A Bayesian Analysis of 52 Countries Worldwide
Juan Carlos Martín-Sánchez; Nuno Lunet; Adrián González-Marrón; Cristina Lidón-Moyano; Nuria Matilla-Santander; Ramon Clèries; Matteo Malvezzi; Eva Negri; Samantha Morais; Ana Rute Costa; Ana Ferro; Luisa Lopes-Conceição; Carlo La Vecchia; Jose M. Martínez-Sánchez
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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