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1 April 2017
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Mice housed in an enriched environment display a remarkable antitumor phenotype. Enriching the housing conditions for mice enhances the tumor infiltration and the cytotoxicity ability of natural killer (NK) cells via sympathetic nerve-dependent regulation of NKG2D and CCR5 expressions on NK cells. The immunohistochemical staining for NK1.1 shows an increased number of infiltrating NK cells in transplanted tumors from enriched environment-housed mice. For details, see article by Song and colleagues on page 1611.Close Modal - PDF Icon PDF LinkTable of Contents
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ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Perspective
Precancer Atlas to Drive Precision Prevention Trials
Avrum Spira; Matthew B. Yurgelun; Ludmil Alexandrov; Anjana Rao; Rafael Bejar; Kornelia Polyak; Marios Giannakis; Ali Shilatifard; Olivera J. Finn; Madhav Dhodapkar; Neil E. Kay; Esteban Braggio; Eduardo Vilar; Sarah A. Mazzilli; Timothy R. Rebbeck; Judy E. Garber; Victor E. Velculescu; Mary L. Disis; Douglas C. Wallace; Scott M. Lippman
Reviews
Integrated Systems and Technologies
Microenvironment and Immunology
Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors
Shannon M. Steinberg; Tamer B. Shabaneh; Peisheng Zhang; Viktor Martyanov; Zhenghui Li; Brian T. Malik; Tamara A. Wood; Andrea Boni; Aleksey Molodtsov; Christina V. Angeles; Tyler J. Curiel; Michael L. Whitfield; Mary Jo Turk
Molecular and Cellular Pathobiology
YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor–Induced Activation of the PI3K Pathway
Chao Wang; Chao Gu; Kang Jin Jeong; Dong Zhang; Wei Guo; Yiling Lu; Zhenlin Ju; Nattapon Panupinthu; Ji Yeon Yang; Mihai (Mike) Gagea; Patrick Kwok Shing Ng; Fan Zhang; Gordon B. Mills
CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer
Mahmoud A. Alfaqih; Erik R. Nelson; Wen Liu; Rachid Safi; Jeffery S. Jasper; Everardo Macias; Joseph Geradts; J. Will Thompson; Laura G. Dubois; Michael R. Freeman; Ching-yi Chang; Jen-Tsan Chi; Donald P. McDonnell; Stephen J. Freedland
Prevention and Epidemiology
Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia
Adam J. de Smith; Maneet Kaur; Semira Gonseth; Alyson Endicott; Steve Selvin; Luoping Zhang; Ritu Roy; Xiaorong Shao; Helen M. Hansen; Alice Y. Kang; Kyle M. Walsh; Gary V. Dahl; Roberta McKean-Cowdin; Catherine Metayer; Joseph L. Wiemels
Therapeutics, Targets, and Chemical Biology
Tumor and Stem Cell Biology
Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma
David M. Walter; Olivia S. Venancio; Elizabeth L. Buza; John W. Tobias; Charuhas Deshpande; A. Andrea Gudiel; Caroline Kim-Kiselak; Michelle Cicchini; Travis J. Yates; David M. Feldser
Author Choice
Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer
Lucy Mathot; Snehangshu Kundu; Viktor Ljungström; Jessica Svedlund; Lotte Moens; Tom Adlerteg; Elin Falk-Sörqvist; Verónica Rendo; Claudia Bellomo; Markus Mayrhofer; Carme Cortina; Magnus Sundström; Patrick Micke; Johan Botling; Anders Isaksson; Aristidis Moustakas; Eduard Batlle; Helgi Birgisson; Bengt Glimelius; Mats Nilsson; Tobias Sjöblom
Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Mia Niklasson; Gianluca Maddalo; Zuzana Sramkova; Ercan Mutlu; Shimei Wee; Petra Sekyrova; Linnéa Schmidt; Nicolas Fritz; Ivar Dehnisch; Gregorios Kyriatzis; Michaela Krafcikova; Brittany B. Carson; Jennifer M. Feenstra; Voichita D. Marinescu; Anna Segerman; Martin Haraldsson; Anna-Lena Gustavsson; Lars G.J. Hammarström; Annika Jenmalm Jensen; Lene Uhrbom; A.F. Maarten Altelaar; Sten Linnarsson; Per Uhlén; Lukas Trantirek; C. Theresa Vincent; Sven Nelander; Per Øyvind Enger; Michael Andäng
Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis
Daria G. Valerio; Haiming Xu; Chun-Wei Chen; Takayuki Hoshii; Meghan E. Eisold; Christopher Delaney; Monica Cusan; Aniruddha J. Deshpande; Chun-Hao Huang; Amaia Lujambio; YuJun George Zheng; Johannes Zuber; Tej K. Pandita; Scott W. Lowe; Scott A. Armstrong
Letters to the Editor
Corrections
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