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15 November 2017
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Cover Image
Cover Image
Apoptotic cells are known to get engulfed by immune cells. However, apoptotic cancer stem cells that resurrect by reconstructing themselves from apoptotic bodies (called blebbishields; red fluorescence) evade phagocytosis by immune cells (green fluorescence) through blebbishield-immune cell fusion to generate hybrid cells (termed PBSHMS cells; cover image was imaged at 1 week after fusion). PBSHMS cells exhibit chromosomal instability and are capable of tumorigenesis, and metastasis in nude mice demonstrates that these hybrids are not the product of phagocytosis. For details, see article by Jinesh and Kamat on page 6144.Close Modal - PDF Icon PDF LinkTable of Contents
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ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Perspective
Molecular and Cellular Pathobiology
Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation
Rui Yang; Lee H. Chen; Landon J. Hansen; Austin B. Carpenter; Casey J. Moure; Heng Liu; Christopher J. Pirozzi; Bill H. Diplas; Matthew S. Waitkus; Paula K. Greer; Huishan Zhu; Roger E. McLendon; Darell D. Bigner; Yiping He; Hai Yan
Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma
Smruthy Sivakumar; F. Anthony San Lucas; Tina L. McDowell; Wenhua Lang; Li Xu; Junya Fujimoto; Jianjun Zhang; P. Andrew Futreal; Junya Fukuoka; Yasushi Yatabe; Steven M. Dubinett; Avrum E. Spira; Jerry Fowler; Ernest T. Hawk; Ignacio I. Wistuba; Paul Scheet; Humam Kadara
Tumor and Stem Cell Biology
Therapeutics, Targets, and Chemical Biology
ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Vivek Shukla; Mahadev Rao; Hongen Zhang; Jeanette Beers; Darawalee Wangsa; Danny Wangsa; Floryne O. Buishand; Yonghong Wang; Zhiya Yu; Holly S. Stevenson; Emily S. Reardon; Kaitlin C. McLoughlin; Andrew S. Kaufman; Eden C. Payabyab; Julie A. Hong; Mary Zhang; Sean Davis; Daniel Edelman; Guokai Chen; Markku M. Miettinen; Nicholas P. Restifo; Thomas Ried; Paul A. Meltzer; David S. Schrump
Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
Suriyan Ponnusamy; Christopher C. Coss; Thirumagal Thiyagarajan; Kate Watts; Dong-Jin Hwang; Yali He; Luke A. Selth; Iain J. McEwan; Charles B. Duke; Jayaprakash Pagadala; Geetika Singh; Robert W. Wake; Christopher Ledbetter; Wayne D. Tilley; Tudor Moldoveanu; James T. Dalton; Duane D. Miller; Ramesh Narayanan
Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases
Michael H. Ross; Alison K. Esser; Gregory C. Fox; Anne H. Schmieder; Xiaoxia Yang; Grace Hu; Dipanjan Pan; Xinming Su; Yalin Xu; Deborah V. Novack; Thomas Walsh; Graham A. Colditz; Gabriel H. Lukaszewicz; Elizabeth Cordell; Joshua Novack; James A. J. Fitzpatrick; David L. Waning; Khalid S. Mohammad; Theresa A. Guise; Gregory M. Lanza; Katherine N. Weilbaecher
Combined CDK4/6 and PI3Kα Inhibition Is Synergistic and Immunogenic in Triple-Negative Breast Cancer
Zhi Ling Teo; Stephanie Versaci; Sathana Dushyanthen; Franco Caramia; Peter Savas; Chris P. Mintoff; Magnus Zethoven; Balaji Virassamy; Stephen J. Luen; Grant A. McArthur; Wayne A. Phillips; Phillip K. Darcy; Sherene Loi
Microenvironment and Immunology
PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer
Benjamin A. Kansy; Fernando Concha-Benavente; Raghvendra M. Srivastava; Hyun-Bae Jie; Gulidanna Shayan; Yu Lei; Jessica Moskovitz; Jennifer Moy; Jing Li; Sven Brandau; Stephan Lang; Nicole C. Schmitt; Gordon J. Freeman; William E. Gooding; David A. Clump; Robert L. Ferris
PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs
Austin K. Mattox; Jina Lee; William H. Westra; Robert H. Pierce; Ronald Ghossein; William C. Faquin; Thomas J. Diefenbach; Luc G. Morris; Derrick T. Lin; Lori J. Wirth; Armida Lefranc-Torres; Eiichi Ishida; Patrick D. Chakravarty; Lauren Johnson; Yang C. Zeng; Huabiao Chen; Mark C. Poznansky; Neil M. Iyengar; Sara I. Pai
Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses
Jessica Ventura; Pavel N. Lobachevsky; Jason S. Palazzolo; Helen Forrester; Nicole M. Haynes; Alesia Ivashkevich; Andrew W. Stevenson; Christopher J. Hall; Andreas Ntargaras; Vasilis Kotsaris; Gerasimos Ch. Pollakis; Gianna Potsi; Konstantinos Skordylis; Georgia Terzoudi; Ioannis S. Pateras; Vassilis G. Gorgoulis; Alexandros G. Georgakilas; Carl N. Sprung; Olga A. Martin
Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression
Richard L. Bakst; Huizhong Xiong; Chun-Hao Chen; Sylvie Deborde; Anna Lyubchik; Yi Zhou; Shizhi He; William McNamara; Sei-Young Lee; Oakley C. Olson; Ingrid M. Leiner; Andrea R. Marcadis; James W. Keith; Hikmat A. Al-Ahmadie; Nora Katabi; Ziv Gil; Efsevia Vakiani; Johanna A. Joyce; Eric Pamer; Richard J. Wong
Integrated Systems and Technologies
Author Choice
In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer
Jakob Nikolas Kather; Jan Poleszczuk; Meggy Suarez-Carmona; Johannes Krisam; Pornpimol Charoentong; Nektarios A. Valous; Cleo-Aron Weis; Luca Tavernar; Florian Leiss; Esther Herpel; Fee Klupp; Alexis Ulrich; Martin Schneider; Alexander Marx; Dirk Jäger; Niels Halama
Prevention and Epidemiology
Correction
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