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Volume 75, Issue 9

1 May 2015

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Cover Image

Cover Image

GPRC5A was repressed, while EGFR was dysregulated, in inflammatory lung tissues (n = 10) in comparison with those in normal lung tissues (n = 10). The inverse correlation between EGFR and GPRC5A was complete, without one exception. IHC staining for GPRC5A in human inflammatory lung tissue is shown in the representative image. For details, see article by Zhong and colleagues on page 1801.
Table of Contents

ISSN 0008-5472

EISSN 1538-7445

Issue Sections

Breaking Advances
Reviews
Integrated Systems and Technologies
Molecular and Cellular Pathobiology
Prevention and Epidemiology
Therapeutics, Targets, and Chemical Biology
Tumor and Stem Cell Biology
Correction

Cancer Research

Breaking Advances

Highlights from Recent Cancer Literature

Extract

View articletitled, Highlights from Recent Cancer Literature

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Reviews

Author Choice

Nerve–Cancer Cell Cross-talk: A Novel Promoter of Tumor Progression

Phillip Jobling; Jay Pundavela; Sonia M.R. Oliveira; Séverine Roselli; Marjorie M. Walker; Hubert Hondermarck

Abstract

View articletitled, Nerve–Cancer Cell Cross-talk: A Novel Promoter of Tumor Progression

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Amino Acid Transporters in Cancer and Their Relevance to “Glutamine Addiction”: Novel Targets for the Design of a New Class of Anticancer Drugs

Yangzom D. Bhutia; Ellappan Babu; Sabarish Ramachandran; Vadivel Ganapathy

Abstract

View articletitled, Amino Acid Transporters in Cancer and Their Relevance to “Glutamine Addiction”: Novel Targets for the Design of a New Class of Anticancer Drugs

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Integrated Systems and Technologies

Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Mark J. Schliekelman; Ayumu Taguchi; Jun Zhu; Xudong Dai; Jaime Rodriguez; Muge Celiktas; Qing Zhang; Alice Chin; Chee-Hong Wong; Hong Wang; Lisa McFerrin; Suhaida A. Selamat; Chenchen Yang; Evan M. Kroh; Kavita S. Garg; Carmen Behrens; Adi F. Gazdar; Ite A. Laird-Offringa; Muneesh Tewari; Ignacio I. Wistuba; Jean P. Thiery; Samir M. Hanash

Abstracts

View articletitled, Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Supplementary data

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Molecular and Cellular Pathobiology

Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Shuangshuang Zhong; Huijing Yin; Yueling Liao; Feng Yao; Qi Li; Jie Zhang; Huike Jiao; Yongxu Zhao; Dongliang Xu; Shuli Liu; Hongyong Song; Yong Gao; Jingyi Liu; Lina Ma; Zhi Pang; Ruixu Yang; Chengyi Ding; Beibei Sun; Xiaofeng Lin; Xiaofeng Ye; Wenzheng Guo; Baohui Han; Binhua P. Zhou; Y. Eugene Chin; Jiong Deng

Abstracts

View articletitled, Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Supplementary data

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Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma

De-Chen Lin; Liang Xu; Ye Chen; Haiyan Yan; Masaharu Hazawa; Ngan Doan; Jonathan W. Said; Ling-Wen Ding; Li-Zhen Liu; Henry Yang; Shizhu Yu; Michael Kahn; Dong Yin; H. Phillip Koeffler

Abstracts

View articletitled, Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma

Supplementary data

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Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry

Sabine Guenther; Laura J. Muirhead; Abigail V.M. Speller; Ottmar Golf; Nicole Strittmatter; Rathi Ramakrishnan; Robert D. Goldin; Emrys Jones; Kirill Veselkov; Jeremy Nicholson; Ara Darzi; Zoltan Takats

Abstracts

View articletitled, Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry

Supplementary data

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CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity

Chenyi Yang; Cynthia A. Boyson; Maurizio Di Liberto; Xiangao Huang; Jeffrey Hannah; David C. Dorn; Malcolm A.S. Moore; Selina Chen-Kiang; Pengbo Zhou

Abstracts

View articletitled, CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity

Supplementary data

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Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

Alexey V. Sorokin; Binoj C. Nair; Yongkun Wei; Kathryn E. Aziz; Valentina Evdokimova; Mien-Chie Hung; Junjie Chen

Abstracts

View articletitled, Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

Supplementary data

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Prevention and Epidemiology

miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24⁺ Progenitor Cells

Jing Zhang; Jingjing Jiao; Silvia Cermelli; Kyle Muir; Kwang Hwa Jung; Ruhai Zou; Asif Rashid; Mihai Gagea; Sonya Zabludoff; Raghu Kalluri; Laura Beretta

Abstracts

View articletitled, miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24<sup>+</sup> Progenitor Cells

Supplementary data

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Therapeutics, Targets, and Chemical Biology

Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2

Valentina Sancisi; Greta Gandolfi; Davide Carlo Ambrosetti; Alessia Ciarrocchi

Abstracts

View articletitled, Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2

Supplementary data

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Tumor and Stem Cell Biology

RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

Matthias Ilmer; Alejandro Recio Boiles; Ivonne Regel; Kenji Yokoi; Christoph W. Michalski; Ignacio I. Wistuba; Jaime Rodriguez; Eckhard Alt; Jody Vykoukal

Abstracts

View articletitled, RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

Supplementary data

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Author Choice

CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival

Nico Ullrich; Anja Heinemann; Elena Nilewski; Inka Scheffrahn; Joachim Klode; André Scherag; Dirk Schadendorf; Bernhard B. Singer; Iris Helfrich

Abstracts

View articletitled, CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival

Supplementary data

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TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation

David J. Drasin; Anna L. Guarnieri; Deepika Neelakantan; Jihye Kim; Joshua H. Cabrera; Chu-An Wang; Vadym Zaberezhnyy; Pierluigi Gasparini; Luciano Cascione; Kay Huebner; Aik-Choon Tan; Heide L. Ford

Abstracts

View articletitled, TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation

Supplementary data

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Correction

Correction: PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

Extract

View articletitled, Correction: <em>PTEN</em> Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

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Journal Archive

Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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Cover Image

Cancer Research

Table of Contents

Breaking Advances

Reviews

Integrated Systems and Technologies

Molecular and Cellular Pathobiology

Prevention and Epidemiology

Therapeutics, Targets, and Chemical Biology

Tumor and Stem Cell Biology

Correction

Journal Archive

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