Skip Nav Destination
Issues
15 September 2015
-
Cover Image
Cover Image
Mast cells located in the gut move in areas of mucosal damage during the process of resolution of acute inflammation and repair. Their activity helps the quenching of inflammatory stimuli, as demonstrated by the delayed tissue repair occurring in mast cell-deficient mice. Mucosal healing is restored upon reconstitution of tissues of mast cell-deficient mice with bone marrow-derived mast cells, as indicated by histology showing the recovered crypt architecture characterizing the intestinal mucosa of reconstituted mice. These pieces of information imply a positive role of the mast cell in the resolution of intestinal inflammation and mucosal healing, which eventually becomes detrimental when transformation towards cancer occurs. For details, see article by Rigoni and colleagues on page 3760.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Meeting Report
Priority Reports
Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis
Amanda Kirane; Kathleen F. Ludwig; Noah Sorrelle; Gry Haaland; Tone Sandal; Renate Ranaweera; Jason E. Toombs; Miao Wang; Sean P. Dineen; David Micklem; Michael T. Dellinger; James B. Lorens; Rolf A. Brekken
Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery
Sarah J. Erickson-Bhatt; Ryan M. Nolan; Nathan D. Shemonski; Steven G. Adie; Jeffrey Putney; Donald Darga; Daniel T. McCormick; Andrew J. Cittadine; Adam M. Zysk; Marina Marjanovic; Eric J. Chaney; Guillermo L. Monroy; Fredrick A. South; Kimberly A. Cradock; Z. George Liu; Magesh Sundaram; Partha S. Ray; Stephen A. Boppart
The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Paul William Harms; Pankaj Vats; Monique Elise Verhaegen; Dan R. Robinson; Yi-Mi Wu; Saravana Mohan Dhanasekaran; Nallasivam Palanisamy; Javed Siddiqui; Xuhong Cao; Fengyun Su; Rui Wang; Hong Xiao; Lakshmi P. Kunju; Rohit Mehra; Scott A. Tomlins; Douglas Randall Fullen; Christopher Keram Bichakjian; Timothy M. Johnson; Andrzej Antoni Dlugosz; Arul M. Chinnaiyan
Integrated Systems and Technologies
Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer
Tong Li; Yak-Nam Wang; Tatiana D. Khokhlova; Samantha D'Andrea; Frank Starr; Hong Chen; Jeannine S. McCune; Linda J. Risler; Afshin Mashadi-Hossein; Sunil R. Hingorani; Amy Chang; Joo Ha Hwang
Microenvironment and Immunology
Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity
Marco Donia; Rikke Andersen; Julie W. Kjeldsen; Paolo Fagone; Shamaila Munir; Ferdinando Nicoletti; Mads Hald Andersen; Per thor Straten; Inge Marie Svane
IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment
Luciana Benevides; Denise Morais da Fonseca; Paula Barbim Donate; Daniel Guimarães Tiezzi; Daniel D. De Carvalho; Jurandyr M. de Andrade; Gislaine A. Martins; João S. Silva
Molecular and Cellular Pathobiology
Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway
Adrian von Witzleben; Lukas T. Goerttler; Ralf Marienfeld; Holger Barth; André Lechel; Kevin Mellert; Michael Böhm; Marko Kornmann; Regine Mayer-Steinacker; Alexandra von Baer; Markus Schultheiss; Adrienne M. Flanagan; Peter Möller; Silke Brüderlein; Thomas F.E. Barth
Therapeutics, Targets, and Chemical Biology
Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53
Shengliang Zhang; Lanlan Zhou; Bo Hong; A. Pieter J. van den Heuvel; Varun V. Prabhu; Noel A. Warfel; Christina Leah B. Kline; David T. Dicker; Levy Kopelovich; Wafik S. El-Deiry
Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies
Laurent Poirot; Brian Philip; Cécile Schiffer-Mannioui; Diane Le Clerre; Isabelle Chion-Sotinel; Sophie Derniame; Pierrick Potrel; Cécile Bas; Laetitia Lemaire; Roman Galetto; Céline Lebuhotel; Justin Eyquem; Gordon Weng-Kit Cheung; Aymeric Duclert; Agnès Gouble; Sylvain Arnould; Karl Peggs; Martin Pule; Andrew M. Scharenberg; Julianne Smith
Author Choice
The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies
Bhavatarini Vangamudi; Thomas A. Paul; Parantu K. Shah; Maria Kost-Alimova; Lisa Nottebaum; Xi Shi; Yanai Zhan; Elisabetta Leo; Harshad S. Mahadeshwar; Alexei Protopopov; Andrew Futreal; Trang N. Tieu; Mike Peoples; Timothy P. Heffernan; Joseph R. Marszalek; Carlo Toniatti; Alessia Petrocchi; Dominique Verhelle; Dafydd R. Owen; Giulio Draetta; Philip Jones; Wylie S. Palmer; Shikhar Sharma; Jannik N. Andersen
Author Choice
ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy
Marie Morfouace; Satish Cheepala; Sadhana Jackson; Yu Fukuda; Yogesh T. Patel; Soghra Fatima; Daisuke Kawauchi; Anang A. Shelat; Clinton F. Stewart; Brian P. Sorrentino; John D. Schuetz; Martine F. Roussel
Tumor and Stem Cell Biology
Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
Min-Zu Wu; Su-Feng Chen; Shin Nieh; Christopher Benner; Luo-Ping Ger; Chia-Ing Jan; Li Ma; Chien-Hung Chen; Tomoaki Hishida; Hong-Tai Chang; Yaoh-Shiang Lin; Nuria Montserrat; Pedro Gascon; Ignacio Sancho-Martinez; Juan Carlos Izpisua Belmonte
Author Choice
KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer
Laia Simó-Riudalbas; Montserrat Pérez-Salvia; Fernando Setien; Alberto Villanueva; Catia Moutinho; Anna Martínez-Cardús; Sebastian Moran; Maria Berdasco; Antonio Gomez; Enrique Vidal; Marta Soler; Holger Heyn; Alejandro Vaquero; Carolina de la Torre; Silvia Barceló-Batllori; August Vidal; Luca Roz; Ugo Pastorino; Katalin Szakszon; Guntram Borck; Conceição S. Moura; Fátima Carneiro; Ilse Zondervan; Suvi Savola; Reika Iwakawa; Takashi Kohno; Jun Yokota; Manel Esteller
Author Choice
Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity
M. Margarida Bernardo; Alexander Kaplun; Sijana H. Dzinic; Xiaohua Li; Jonathan Irish; Adelina Mujagic; Benjamin Jakupovic; Jessica B. Back; Eric Van Buren; Xiang Han; Ivory Dean; Yong Q. Chen; Elisabeth Heath; Wael Sakr; Shijie Sheng
Letters to the Editor
Corrections
Advertisement