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15 June 2015
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Cover Image
Ultrasound is a complementary imaging modality for detection of mammographically occult breast cancers, especially in patients with dense breast tissue. Diagnostic accuracy of ultrasound in these patients can be significantly improved using contrast agents targeted at molecular signatures on the tumor neovasculature. In a large scale immunohistochemcical staining analysis of human tissues, it was found that B7-H3 is differentially expressed in breast cancer–associated vascular endothelial cells compared with normal, benign, and precursor lesions. Also, B7-H3-targeted ultrasound molecular imaging allowed detection of breast cancer in a transgenic mouse model of breast cancer development. For details, see article by Bachawal and colleagues on page 2501.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Integrated Systems and Technologies
Microenvironment and Immunology
Author Choice
Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer
Sara I. Cunha; Matteo Bocci; John Lövrot; Nikolas Eleftheriou; Pernilla Roswall; Eugenia Cordero; Linda Lindström; Michael Bartoschek; B. Kristian Haller; R. Scott Pearsall; Aaron W. Mulivor; Ravindra Kumar; Christer Larsson; Jonas Bergh; Kristian Pietras
Prevention and Epidemiology
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures
Jennifer Stone; Deborah J. Thompson; Isabel dos Santos Silva; Christopher Scott; Rulla M. Tamimi; Sara Lindstrom; Peter Kraft; Aditi Hazra; Jingmei Li; Louise Eriksson; Kamila Czene; Per Hall; Matt Jensen; Julie Cunningham; Janet E. Olson; Kristen Purrington; Fergus J. Couch; Judith Brown; Jean Leyland; Ruth M.L. Warren; Robert N. Luben; Kay-Tee Khaw; Paula Smith; Nicholas J. Wareham; Sebastian M. Jud; Katharina Heusinger; Matthias W. Beckmann; Julie A. Douglas; Kaanan P. Shah; Heang-Ping Chan; Mark A. Helvie; Loic Le Marchand; Laurence N. Kolonel; Christy Woolcott; Gertraud Maskarinec; Christopher Haiman; Graham G. Giles; Laura Baglietto; Kavitha Krishnan; Melissa C. Southey; Carmel Apicella; Irene L. Andrulis; Julia A. Knight; Giske Ursin; Grethe I. Grenaker Alnaes; Vessela N. Kristensen; Anne-Lise Borresen-Dale; Inger Torhild Gram; Manjeet K. Bolla; Qin Wang; Kyriaki Michailidou; Joe Dennis; Jacques Simard; Paul Pharoah; Alison M. Dunning; Douglas F. Easton; Peter A. Fasching; V. Shane Pankratz; John L. Hopper; Celine M. Vachon
Therapeutics, Targets, and Chemical Biology
Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
Eric A. Lee; Leonard Angka; Sarah-Grace Rota; Thomas Hanlon; Andrew Mitchell; Rose Hurren; Xiao Ming Wang; Marcela Gronda; Ezel Boyaci; Barbara Bojko; Mark Minden; Shrivani Sriskanthadevan; Alessandro Datti; Jeffery L. Wrana; Andrea Edginton; Janusz Pawliszyn; Jamie W. Joseph; Joe Quadrilatero; Aaron D. Schimmer; Paul A. Spagnuolo
Author Choice
Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
Catherine A. Eberlein; Daniel Stetson; Aleksandra A. Markovets; Katherine J. Al-Kadhimi; Zhongwu Lai; Paul R. Fisher; Catherine B. Meador; Paula Spitzler; Eiki Ichihara; Sarah J. Ross; Miika J. Ahdesmaki; Ambar Ahmed; Laura E. Ratcliffe; Elizabeth L. Christey O'Brien; Claire H. Barnes; Henry Brown; Paul D. Smith; Jonathan R. Dry; Garry Beran; Kenneth S. Thress; Brian Dougherty; William Pao; Darren A.E. Cross
Author Choice
Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids
Andrew D. Southam; Farhat L. Khanim; Rachel E. Hayden; Julia K. Constantinou; Katarzyna M. Koczula; Robert H. Michell; Mark R. Viant; Mark T. Drayson; Chris M. Bunce
Tumor and Stem Cell Biology
Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis
Hiromi I. Wettersten; A. Ari Hakimi; Dexter Morin; Cristina Bianchi; Megan E. Johnstone; Dallas R. Donohoe; Josephine F. Trott; Omran Abu Aboud; Steven Stirdivant; Bruce Neri; Robert Wolfert; Benjamin Stewart; Roberto Perego; James J. Hsieh; Robert H. Weiss
Author Choice
Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State
Chian-Shiu Chien; Mong-Lien Wang; Pen-Yuan Chu; Yuh-Lih Chang; Wei-Hsiu Liu; Cheng-Chia Yu; Yuan-Tzu Lan; Pin-I. Huang; Yi-Yen Lee; Yi-Wei Chen; Wen-Liang Lo; Shih-Hwa Chiou
Corrections
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