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15 March 2014
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Pancreas from a 12-week-old KPCT (p48-Cre; LSL-KrasG12D; p53Lox/7+; Rosa26-LSL-tdTomato) mouse with precancerous PanIN lesions but no tumor. dtTomato-label (red) marks pancreas epithelial-derived cells, in this case normal-appearing acinar cells. PGP 9.5 antibody (green) was used to stain nerve fibers that exhibit hypertrophy and sprouting within pancreatic tissue, beginning at histologic precancer stages and increasing as the disease progresses. For details, see article by Stopczynski and colleagues on page 1718.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Priority Reports
PCAT-1, a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer
John R. Prensner; Wei Chen; Matthew K. Iyer; Qi Cao; Teng Ma; Sumin Han; Anirban Sahu; Rohit Malik; Kari Wilder-Romans; Nora Navone; Christopher J. Logothetis; John C. Araujo; Louis L. Pisters; Ashutosh K. Tewari; Christine E. Canman; Karen E. Knudsen; Naoki Kitabayashi; Mark A. Rubin; Francesca Demichelis; Theodore S. Lawrence; Arul M. Chinnaiyan; Felix Y. Feng
Integrated Systems and Technologies
Microenvironment and Immunology
Molecular and Cellular Pathobiology
Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer
Gunnar Steinert; Sebastian Schölch; Thomas Niemietz; Naoki Iwata; Sebastián A. García; Bianca Behrens; Anita Voigt; Matthias Kloor; Axel Benner; Ulrich Bork; Nuh N. Rahbari; Markus W. Büchler; Nikolas H. Stoecklein; Jürgen Weitz; Moritz Koch
HDAC2 Provides a Critical Support to Malignant Progression of Hepatocellular Carcinoma through Feedback Control of mTORC1 and AKT
Ji Heon Noh; Hyun Jin Bae; Jung Woo Eun; Qingyu Shen; Se Jin Park; Hyung Seok Kim; Boas Nam; Woo Chan Shin; Eun Kyung Lee; Kyungbun Lee; Ja-Jun Jang; Won Sang Park; Jung Young Lee; Suk Woo Nam
Therapeutics, Targets, and Chemical Biology
Genetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma
Fengting Yan; Lapo Alinari; Mark E. Lustberg; Ludmila Katherine Martin; Hector M. Cordero-Nieves; Yeshavanth Banasavadi-Siddegowda; Selene Virk; Jill Barnholtz-Sloan; Erica Hlavin Bell; Jeffrey Wojton; Naduparambil K. Jacob; Arnab Chakravarti; Michal O. Nowicki; Xin Wu; Rosa Lapalombella; Jharna Datta; Bo Yu; Kate Gordon; Amy Haseley; John T. Patton; Porsha L. Smith; John Ryu; Xiaoli Zhang; Xiaokui Mo; Guido Marcucci; Gerard Nuovo; Chang-Hyuk Kwon; John C. Byrd; E. Antonio Chiocca; Chenglong Li; Said Sif; Samson Jacob; Sean Lawler; Balveen Kaur; Robert A. Baiocchi
Author Choice
ATDC/TRIM29 Phosphorylation by ATM/MAPKAP Kinase 2 Mediates Radioresistance in Pancreatic Cancer Cells
Lidong Wang; Huibin Yang; Phillip L. Palmbos; Gina Ney; Taylor Ann Detzler; Dawn Coleman; Jacob Leflein; Mary Davis; Min Zhang; Wenhua Tang; J. Kevin Hicks; Corey M. Helchowski; Jayendra Prasad; Theodore S. Lawrence; Liang Xu; Xiaochun Yu; Christine E. Canman; Mats Ljungman; Diane M. Simeone
miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
Jian-Jun Zhao; Jianhong Lin; Di Zhu; Xujun Wang; Daniel Brooks; Ming Chen; Zhang-Bo Chu; Kohichi Takada; Bryan Ciccarelli; Samir Admin; Jianguo Tao; Yu-Tzu Tai; Steven Treon; Geraldine Pinkus; Winston Patrick Kuo; Teru Hideshima; Mary Bouxsein; Nikhil Munshi; Kenneth Anderson; Ruben Carrasco
Tumor and Stem Cell Biology
Sox2 Is Required to Maintain Cancer Stem Cells in a Mouse Model of High-Grade Oligodendroglioma
Rebecca Favaro; Irene Appolloni; Serena Pellegatta; Alexandra Badiola Sanga; Pierfrancesco Pagella; Eleonora Gambini; Federica Pisati; Sergio Ottolenghi; Maria Foti; Gaetano Finocchiaro; Paolo Malatesta; Silvia K. Nicolis
Author Choice
Expression of Variant Isoforms of the Tyrosine Kinase SYK Determines the Prognosis of Hepatocellular Carcinoma
Jian Hong; Yunfei Yuan; Jianping Wang; Yadi Liao; Ruhai Zou; Chuanlong Zhu; Binkui Li; Yi Liang; Pinzhu Huang; Zongwei Wang; Wenyu Lin; Yixin Zeng; Jia Le Dai; Raymond T. Chung
MET Signaling in Colon Cancer Stem-like Cells Blunts the Therapeutic Response to EGFR Inhibitors
Paolo Luraghi; Gigliola Reato; Elia Cipriano; Francesco Sassi; Francesca Orzan; Viola Bigatto; Francesca De Bacco; Elena Menietti; May Han; William M. Rideout, III; Timothy Perera; Andrea Bertotti; Livio Trusolino; Paolo M. Comoglio; Carla Boccaccio
Correction
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