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1 February 2014
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Cover Image
Focal adhesion signaling activates several pathways related to cancer cell migration and invasion. As seen under confocal microscope, immunofluorescence-decorated proteins of a cancer cell, the mature focal adhesion complexes in green form punctates on cell peripheral, whereas actin cables in red form the boundary of the cell peripheral. The miR-491-5p inhibited focal adhesion formation and thus cancer cell migration via targeting GIT1, a scaffold protein that interacts with paxillin and is important for the formation of mature focal adhesion complexes. Re-expression of GIT1 reversed miR-491-5p-mediated inhibition of focal adhesion formation. For details, see article by Wei-Chieh Huang and colleagues on page 751.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Perspective
Priority Report
Integrated Systems and Technologies
Microenvironment and Immunology
Author Choice
Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Jérémy Goc; Claire Germain; Thi Kim Duy Vo-Bourgais; Audrey Lupo; Christophe Klein; Samantha Knockaert; Luc de Chaisemartin; Hanane Ouakrim; Etienne Becht; Marco Alifano; Pierre Validire; Romain Remark; Scott A. Hammond; Isabelle Cremer; Diane Damotte; Wolf-Herman Fridman; Catherine Sautès-Fridman; Marie-Caroline Dieu-Nosjean
Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
Agnieszka Bronisz; Yan Wang; Michal O. Nowicki; Pierpaolo Peruzzi; Khairul I. Ansari; Daisuke Ogawa; Leonora Balaj; Gianluca De Rienzo; Marco Mineo; Ichiro Nakano; Michael C. Ostrowski; Fred Hochberg; Ralph Weissleder; Sean E. Lawler; E. Antonio Chiocca; Jakub Godlewski
Molecular and Cellular Pathobiology
Author Choice
miRNA-491-5p and GIT1 Serve as Modulators and Biomarkers for Oral Squamous Cell Carcinoma Invasion and Metastasis
Wei-Chieh Huang; Shih-Hsuan Chan; Te-Hsuan Jang; Jer-Wei Chang; Ying-Chin Ko; Tzu-Chen Yen; Shang-Lun Chiang; Wei-Fan Chiang; Tien-Yu Shieh; Chun-Ta Liao; Jyh-Lyh Juang; Hsueh-Chun Wang; Ann-Joy Cheng; Ya-Ching Lu; Lu-Hai Wang
Prevention and Epidemiology
Risk of Ovarian Cancer and the NF-κB Pathway: Genetic Association with IL1A and TNFSF10
Bridget Charbonneau; Matthew S. Block; William R. Bamlet; Robert A. Vierkant; Kimberly R. Kalli; Zachary Fogarty; David N. Rider; Thomas A. Sellers; Shelley S. Tworoger; Elizabeth Poole; Harvey A. Risch; Helga B. Salvesen; Lambertus A. Kiemeney; Laura Baglietto; Graham G. Giles; Gianluca Severi; Britton Trabert; Nicolas Wentzensen; Georgia Chenevix-Trench; for AOCS/ACS group; Alice S. Whittemore; Weiva Sieh; Jenny Chang-Claude; Elisa V. Bandera; Irene Orlow; Kathryn Terry; Marc T. Goodman; Pamela J. Thompson; Linda S. Cook; Mary Anne Rossing; Roberta B. Ness; Steven A. Narod; Jolanta Kupryjanczyk; Karen Lu; Ralf Butzow; Thilo Dörk; Tanja Pejovic; Ian Campbell; Nhu D. Le; Clareann H. Bunker; Natalia Bogdanova; Ingo B. Runnebaum; Diana Eccles; James Paul; Anna H. Wu; Simon A. Gayther; Estrid Hogdall; Florian Heitz; Stanley B. Kaye; Beth Y. Karlan; Hoda Anton-Culver; Jacek Gronwald; Claus K. Hogdall; Diether Lambrechts; Peter A. Fasching; Usha Menon; Joellen Schildkraut; Celeste Leigh Pearce; Douglas A. Levine; Susanne Kruger Kjaer; Daniel Cramer; James M. Flanagan; Catherine M. Phelan; Robert Brown; Leon F.A.G. Massuger; Honglin Song; Jennifer A. Doherty; Camilla Krakstad; Dong Liang; Kunle Odunsi; Andrew Berchuck; Allan Jensen; Jan Lubiński; Heli Nevanlinna; Yukie T. Bean; Galina Lurie; Argyrios Ziogas; Christine Walsh; Evelyn Despierre; Louise Brinton; Alexander Hein; Anja Rudolph; Agnieszka Dansonka-Mieszkowska; Sara H. Olson; Philipp Harter; Jonathan Tyrer; Allison F. Vitonis; Angela Brooks-Wilson; Katja K. Aben; Malcolm C. Pike; Susan J. Ramus; Elisabeth Wik; Cezary Cybulski; Jie Lin; Lara Sucheston; Robert Edwards; Valerie McGuire; Jenny Lester; Andreas du Bois; Lene Lundvall; Shan Wang-Gohrke; Lukasz M. Szafron; Sandrina Lambrechts; Hannah Yang; Matthias W. Beckmann; Liisa M. Pelttari; Anne M. Van Altena; David van den Berg; Mari K. Halle; Aleksandra Gentry-Maharaj; Ira Schwaab; Urmila Chandran; Janusz Menkiszak; Arif B. Ekici; Lynne R. Wilkens; Arto Leminen; Francesmary Modugno; Grace Friel; Joseph H. Rothstein; Ignace Vergote; Montserrat Garcia-Closas; Michelle A.T. Hildebrandt; Piotr Sobiczewski; Linda E. Kelemen; Paul D.P. Pharoah; Kirsten Moysich; Keith L. Knutson; Julie M. Cunningham; Brooke L. Fridley; Ellen L. Goode
Therapeutics, Targets, and Chemical Biology
Author Choice
Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging
Michael D. Allen; Phuong Luong; Chantelle Hudson; Julius Leyton; Barbara Delage; Essam Ghazaly; Rosalind Cutts; Ming Yuan; Nelofer Syed; Cristiana Lo Nigro; Laura Lattanzio; Malgorzata Chmielewska-Kassassir; Ian Tomlinson; Rebecca Roylance; Hayley C. Whitaker; Anne Y. Warren; David Neal; Christian Frezza; Luis Beltran; Louise J. Jones; Claude Chelala; Bor-Wen Wu; John S. Bomalaski; Robert C. Jackson; Yong-Jie Lu; Tim Crook; Nicholas R. Lemoine; Stephen Mather; Julie Foster; Jane Sosabowski; Norbert Avril; Chien-Feng Li; Peter W. Szlosarek
Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Joanne R. Doherty; Chunying Yang; Kristen E.N. Scott; Michael D. Cameron; Mohammad Fallahi; Weimin Li; Mark A. Hall; Antonio L. Amelio; Jitendra K. Mishra; Fangzheng Li; Mariola Tortosa; Heide Marika Genau; Robert J. Rounbehler; Yunqi Lu; Chi V. Dang; K. Ganesh Kumar; Andrew A. Butler; Thomas D. Bannister; Andrea T. Hooper; Keziban Unsal-Kacmaz; William R. Roush; John L. Cleveland
Nutlin-3a Efficacy in Sarcoma Predicted by Transcriptomic and Epigenetic Profiling
Kathleen I. Pishas; Susan J. Neuhaus; Mark T. Clayer; Andreas W. Schreiber; David M. Lawrence; Michelle Perugini; Robert J. Whitfield; Gelareh Farshid; Jim Manavis; Steve Chryssidis; Bronwen J. Mayo; Rebecca C. Haycox; Kristen Ho; Michael P. Brown; Richard J. D'Andrea; Andreas Evdokiou; David M. Thomas; Jayesh Desai; David F. Callen; Paul M. Neilsen
Tumor and Stem Cell Biology
Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis
Wen Liu; Benjamin H. Beck; Kedar S. Vaidya; Kevin T. Nash; Kyle P. Feeley; Scott W. Ballinger; Keke M. Pounds; Warren L. Denning; Anne R. Diers; Aimee Landar; Animesh Dhar; Tomoo Iwakuma; Danny R. Welch
Retraction
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