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1 December 2014
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Cover Image
Cover Image
The image shows a high resolution X-ray of a mouse hip and tumor-bearing mouse femur that was treated with anti-nerve growth antibody. Radiographs of the femur demonstrated that at day 28 postinjection of sarcoma cancer cells into the femur, early and sustained sequestration of nerve growth factor not only reduced bone cancer pain but attenuated sarcoma-induced bone destruction and delayed time to fracture. For details, see article by McCaffrey and colleagues on page 7014.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Microenvironment and Immunology
EGFR Activation and Signaling in Cancer Cells Are Enhanced by the Membrane-Bound Metalloprotease MT4-MMP
Alexandra Paye; Alice Truong; Cassandre Yip; Jonathan Cimino; Silvia Blacher; Carine Munaut; Didier Cataldo; Jean Michel Foidart; Erik Maquoi; Joelle Collignon; Philippe Delvenne; Guy Jerusalem; Agnès Noel; Nor Eddine Sounni
Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
Lore Lapeire; An Hendrix; Kathleen Lambein; Mieke Van Bockstal; Geert Braems; Rudy Van Den Broecke; Ridha Limame; Pieter Mestdagh; Jo Vandesompele; Christian Vanhove; Dawn Maynard; Camille Lehuédé; Catherine Muller; Philippe Valet; Christian P. Gespach; Marc Bracke; Veronique Cocquyt; Hannelore Denys; Olivier De Wever
ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy
Yosra Messai; Muhammad Zaeem Noman; Meriem Hasmim; Bassam Janji; Andrés Tittarelli; Marie Boutet; Véronique Baud; Elodie Viry; Katy Billot; Arash Nanbakhsh; Thouraya Ben Safta; Catherine Richon; Sophie Ferlicot; Emmanuel Donnadieu; Sophie Couve; Betty Gardie; Florence Orlanducci; Laurence Albiges; Jerome Thiery; Daniel Olive; Bernard Escudier; Salem Chouaib
Molecular and Cellular Pathobiology
Author Choice
Nuclear Factor of Activated T-cell Activity Is Associated with Metastatic Capacity in Colon Cancer
Manish K. Tripathi; Natasha G. Deane; Jing Zhu; Hanbing An; Shinji Mima; Xiaojing Wang; Sekhar Padmanabhan; Zhiao Shi; Naresh Prodduturi; Kristen K. Ciombor; Xi Chen; M. Kay Washington; Bing Zhang; R. Daniel Beauchamp
Prevention and Epidemiology
Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
Renée T. Fortner; Helena Schock; Rudolf Kaaks; Matti Lehtinen; Eero Pukkala; Hans-Åke Lakso; Minna Tanner; Raija Kallio; Heikki Joensuu; Kjell Grankvist; Anne Zeleniuch-Jacquotte; Paolo Toniolo; Eva Lundin; Helja-Marja Surcel
Therapeutics, Targets, and Chemical Biology
ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses
Rozenn Jossé; Scott E. Martin; Rajarshi Guha; Pinar Ormanoglu; Thomas D. Pfister; Philip M. Reaper; Christopher S. Barnes; Julie Jones; Peter Charlton; John R. Pollard; Joel Morris; James H. Doroshow; Yves Pommier
Patient-Derived Ovarian Tumor Xenografts Recapitulate Human Clinicopathology and Genetic Alterations
Francesca Ricci; Francesca Bizzaro; Marta Cesca; Federica Guffanti; Monica Ganzinelli; Alessandra Decio; Carmen Ghilardi; Patrizia Perego; Robert Fruscio; Alessandro Buda; Rodolfo Milani; Paola Ostano; Giovanna Chiorino; Maria Rosa Bani; Giovanna Damia; Raffaella Giavazzi
Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
Gregory N. Gan; Justin Eagles; Stephen B. Keysar; Guoliang Wang; Magdalena J. Glogowska; Cem Altunbas; Ryan T. Anderson; Phuong N. Le; J. Jason Morton; Barbara Frederick; David Raben; Xiao-Jing Wang; Antonio Jimeno
Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Y.N. Vashisht Gopal; Helen Rizos; Guo Chen; Wanleng Deng; Dennie T. Frederick; Zachary A. Cooper; Richard A. Scolyer; Gulietta Pupo; Kakajan Komurov; Vasudha Sehgal; Jiexin Zhang; Lalit Patel; Cristiano G. Pereira; Bradley M. Broom; Gordon B. Mills; Prahlad Ram; Paul D. Smith; Jennifer A. Wargo; Georgina V. Long; Michael A. Davies
Chemotherapeutic Agents Subvert Tumor Immunity by Generating Agonists of Platelet-Activating Factor
Ravi P. Sahu; Jesus A. Ocana; Kathleen A. Harrison; Matheus Ferracini; Christopher E. Touloukian; Mohammed Al-Hassani; Louis Sun; Mathew Loesch; Robert C. Murphy; Sandra K. Althouse; Susan M. Perkins; Paul J. Speicher; Douglas S. Tyler; Raymond L. Konger; Jeffrey B. Travers
Tumor and Stem Cell Biology
Author Choice
CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines
Daniela Sicoli; Xuanmao Jiao; Xiaoming Ju; Marco Velasco-Velazquez; Adam Ertel; Sankar Addya; Zhiping Li; Sebastiano Andò; Alessandro Fatatis; Bishnuhari Paudyal; Massimo Cristofanilli; Mathew L. Thakur; Michael P. Lisanti; Richard G. Pestell
Author Choice
Changes in Pyruvate Metabolism Detected by Magnetic Resonance Imaging Are Linked to DNA Damage and Serve as a Sensor of Temozolomide Response in Glioblastoma Cells
Ilwoo Park; Joydeep Mukherjee; Motokazu Ito; Myriam M. Chaumeil; Llewellyn E. Jalbert; Karin Gaensler; Sabrina M. Ronen; Sarah J. Nelson; Russell O. Pieper
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