Issues
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Cover Image
Cover Image
Photograph showing skinfold chambers with implanted mammary carcinoma in mice with normal (large image) and low (small image) platelet counts. Thrombocytopenia resulted in specific bleeding of the tumor. The lack of platelets induced breaches in the tumor vasculature that promoted extravasation of red blood cells and specifically increased the delivery of chemotherapeutic agents into the tumor. Thus, by favoring accumulation of the drug at the tumor site, low platelet count improved its effects and reduced tumor growth. For details, see the article by Demers and colleagues on page 1540 of this issue. - PDF Icon PDF LinkTable of Contents
Cancer Research
Table of Contents
Breaking Advances
Reviews
Priority Reports
Microenvironment and Immunology
Natural Killer Cells Efficiently Reject Lymphoma Silenced for the Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing
TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer
Novel Role for STAT3 in Transcriptional Regulation of NK Immune Cell Targeting Receptor MICA on Cancer Cells
Mast Cell 5-Lipoxygenase Activity Promotes Intestinal Polyposis in APCΔ468 Mice
Molecular and Cellular Pathobiology
The HIF-1–Inducible Lysyl Oxidase Activates HIF-1 via the Akt Pathway in a Positive Regulation Loop and Synergizes with HIF-1 in Promoting Tumor Cell Growth
Ulcerative Colitis–Associated Colorectal Cancer Arises in a Field of Short Telomeres, Senescence, and Inflammation
MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers
Rho Kinase Phosphorylation Promotes Ezrin-Mediated Metastasis in Hepatocellular Carcinoma
Epigenetic Silencing Mediated through Activated PI3K/AKT Signaling in Breast Cancer
Prevention and Epidemiology
Therapeutics, Targets, and Chemical Biology
Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases
Trastuzumab Has Preferential Activity against Breast Cancers Driven by HER2 Homodimers
Tumor and Stem Cell Biology
The ΔNp63 Proteins Are Key Allies of BRCA1 in the Prevention of Basal-Like Breast Cancer
Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells
Corrections
Journal Archive
Cancer Research
(1941-Present; volumes 1-current)Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)
The American Journal of Cancer
(1931-1940; volumes 15-40)Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)
The Journal of Cancer Research
(1916-1930); volumes 1-14)Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)
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