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Volume 71, Issue 20
15 October 2011
Cancer Research Cover Image for Volume 71, Issue 20
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  • Cover Image

    Cover Image

    Issue cover image
    Breast tumor development in 7-week-old PyMT/Kiss1r+/− mouse. Whole mounting of the fourth inguinal mammary fat pad of 7-week-old PyMT/Kiss1r+/− mouse shows hyperplastic nodules. Kiss1r heterozygosity in MMTV-PyMT mouse reduced hyperplastic nodule numbers and delayed tumor initiation and formation. For details, see the article by Cho and colleagues on page 6535 of this issue.
  • PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Breaking Advances

Highlights from Recent Cancer Literature
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Reviews

Resuscitating Wild-Type p53 Expression by Disrupting Ceramide Glycosylation: A Novel Approach to Target Mutant p53 Tumors
Yong-Yu Liu
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Treatment of Hematologic Malignancies with Immunotoxins and Antibody-Drug Conjugates
David J. FitzGerald; Alan S. Wayne; Robert J. Kreitman; Ira Pastan
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Priority Reports

Regulator of G Protein Signaling 6 Mediates Doxorubicin-Induced ATM and p53 Activation by a Reactive Oxygen Species–Dependent Mechanism
Jie Huang; Jianqi Yang; Biswanath Maity; Daisuke Mayuzumi; Rory A. Fisher
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Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
Ryunosuke Kogo; Teppei Shimamura; Koshi Mimori; Kohichi Kawahara; Seiya Imoto; Tomoya Sudo; Fumiaki Tanaka; Kohei Shibata; Akira Suzuki; Shizuo Komune; Satoru Miyano; Masaki Mori
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Integrated Systems and Technologies

Evolution of Tumor Invasiveness: The Adaptive Tumor Microenvironment Landscape Model
Hyung-Ok Lee; Ariosto S. Silva; Susanna Concilio; Yue-Sheng Li; Michael Slifker; Robert A. Gatenby; Jonathan D. Cheng
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p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Devin T. Rosenthal; Harish Iyer; Silvia Escudero; Liwei Bao; Zhifen Wu; Alejandra C. Ventura; Celina G. Kleer; Ellen M. Arruda; Krishna Garikipati; Sofia D. Merajver
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Antiangiogenic Agent Sunitinib Transiently Increases Tumor Oxygenation and Suppresses Cycling Hypoxia
Shingo Matsumoto; Sonny Batra; Keita Saito; Hironobu Yasui; Rajani Choudhuri; Chandramouli Gadisetti; Sankaran Subramanian; Nallathamby Devasahayam; Jeeva P. Munasinghe; James B. Mitchell; Murali C. Krishna
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Activation of the Glucocorticoid Receptor Is Associated with Poor Prognosis in Estrogen Receptor-Negative Breast Cancer
Deng Pan; Masha Kocherginsky; Suzanne D. Conzen
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Microenvironment and Immunology

Glioblastoma Angiogenesis and Tumor Cell Invasiveness Are Differentially Regulated by β8 Integrin
Jeremy H. Tchaicha; Steve B. Reyes; Jaekyung Shin; Mohammad G. Hossain; Frederick F. Lang; Joseph H. McCarty
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TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects
Michele Sommariva; Loris De Cecco; Michelandrea De Cesare; Lucia Sfondrini; Sylvie Ménard; Cecilia Melani; Domenico Delia; Nadia Zaffaroni; Graziella Pratesi; Valentina Uva; Elda Tagliabue; Andrea Balsari
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Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer
Luc de Chaisemartin; Jérémy Goc; Diane Damotte; Pierre Validire; Pierre Magdeleinat; Marco Alifano; Isabelle Cremer; Wolf-Herman Fridman; Catherine Sautès-Fridman; Marie-Caroline Dieu-Nosjean
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Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
Irina Daurkin; Evgeniy Eruslanov; Taryn Stoffs; George Q. Perrin; Chester Algood; Scott M. Gilbert; Charles J. Rosser; Li-Ming Su; Johannes Vieweg; Sergei Kusmartsev
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IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis
Antje Ksienzyk; Berit Neumann; Ramya Nandakumar; Katja Finsterbusch; Martina Grashoff; Rainer Zawatzky; Günter Bernhardt; Hansjörg Hauser; Andrea Kröger
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Asialoglycoprotein Receptor Promotes Cancer Metastasis by Activating the EGFR–ERK Pathway
Suguru Ueno; Marija Mojic; Yoshimi Ohashi; Nobuaki Higashi; Yoshihiro Hayakawa; Tatsuro Irimura
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Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells
Stefan Nierkens; Martijn H. den Brok; Zacharias Garcia; Susan Togher; Jori Wagenaars; Melissa Wassink; Louis Boon; Theo J. Ruers; Carl G. Figdor; Stephen P. Schoenberger; Gosse J. Adema; Edith M. Janssen
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Molecular and Cellular Pathobiology

Enhancement of TGF-β Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer
Vikas Sharma; Anna G. Antonacopoulou; Shinya Tanaka; Alexios A. Panoutsopoulos; Vasiliki Bravou; Haralabos P. Kalofonos; Vasso Episkopou
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miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer
Tomohiko Tsuruta; Ken-ichi Kozaki; Atsushi Uesugi; Mayuko Furuta; Akira Hirasawa; Issei Imoto; Nobuyuki Susumu; Daisuke Aoki; Johji Inazawa
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Pivotal Role of Reduced let-7g Expression in Breast Cancer Invasion and Metastasis
Pengxu Qian; Zehua Zuo; Zhengsheng Wu; Xianyi Meng; Gaopeng Li; Zhengzhou Wu; Weijie Zhang; Sheng Tan; Vijay Pandey; Yandan Yao; Puyue Wang; Liqing Zhao; Jun Wang; Qiang Wu; Erwei Song; Peter E. Lobie; Zhinan Yin; Tao Zhu
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Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Yizeng Yang; Hiroshi Nakagawa; Marie-Pier Tetreault; Janelle Billig; Noel Victor; Abha Goyal; Antonia R. Sepulveda; Jonathan P. Katz
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Long-lived Inflammatory Signaling in Irradiated Bone Marrow Is Genome Dependent
Sally A. Lorimore; Debayan Mukherjee; Joanne I. Robinson; Jennifer A. Chrystal; Eric G. Wright
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Therapeutics, Targets, and Chemical Biology

Tissue Factor–Activated Coagulation Cascade in the Tumor Microenvironment Is Critical for Tumor Progression and an Effective Target for Therapy
Yuan Liu; Pengfei Jiang; Katerina Capkova; Dong Xue; Longwu Ye; Subhash C. Sinha; Nigel Mackman; Kim D. Janda; Cheng Liu
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Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Changmeng Cai; Sen Chen; Patrick Ng; Glenn J. Bubley; Peter S. Nelson; Elahe A. Mostaghel; Brett Marck; Alvin M. Matsumoto; Nicholas I. Simon; Hongyun Wang; Shaoyong Chen; Steven P. Balk
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Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Seok-Geun Lee; Keetae Kim; Timothy P. Kegelman; Rupesh Dash; Swadesh K. Das; Jung Kyoung Choi; Luni Emdad; Eric L. Howlett; Hyun Yong Jeon; Zhao Zhong Su; Byoung Kwon Yoo; Devanand Sarkar; Sung-Hoon Kim; Dong-Chul Kang; Paul B. Fisher
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ZNF668 Functions as a Tumor Suppressor by Regulating p53 Stability and Function in Breast Cancer
Ruozhen Hu; Guang Peng; Hui Dai; Eun-Kyoung Breuer; Katherine Stemke-Hale; Kaiyi Li; Ana M. Gonzalez-Angulo; Gordon B. Mills; Shiaw-Yih Lin
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Tumor and Stem Cell Biology

Haploinsufficiency in the Prometastasis Kiss1 Receptor Gpr54 Delays Breast Tumor Initiation, Progression, and Lung Metastasis
Sung-Gook Cho; Ying Wang; Melissa Rodriguez; Kunrong Tan; Wenzheng Zhang; Jian Luo; Dali Li; Mingyao Liu
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A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
Rae H. Farnsworth; Tara Karnezis; Ramin Shayan; Masataka Matsumoto; Cameron J. Nowell; Marc G. Achen; Steven A. Stacker
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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