Skip to Main Content

Advertisement

Umbrella Alt Text
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 71, Issue 20
15 October 2011
Issue Cover
All Issues
  • Cover Image

    Cover Image

    issue cover
    Breast tumor development in 7-week-old PyMT/Kiss1r+/− mouse. Whole mounting of the fourth inguinal mammary fat pad of 7-week-old PyMT/Kiss1r+/− mouse shows hyperplastic nodules. Kiss1r heterozygosity in MMTV-PyMT mouse reduced hyperplastic nodule numbers and delayed tumor initiation and formation. For details, see the article by Cho and colleagues on page 6535 of this issue.
  • PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Breaking Advances

Highlights from Recent Cancer Literature
View articletitled, Highlights from Recent Cancer Literature
Open the PDF for in another window

Reviews

Resuscitating Wild-Type p53 Expression by Disrupting Ceramide Glycosylation: A Novel Approach to Target Mutant p53 Tumors
Yong-Yu Liu
View articletitled, Resuscitating Wild-Type p53 Expression by Disrupting Ceramide Glycosylation: A Novel Approach to Target Mutant p53 Tumors
Open the PDF for in another window
Treatment of Hematologic Malignancies with Immunotoxins and Antibody-Drug Conjugates
David J. FitzGerald; Alan S. Wayne; Robert J. Kreitman; Ira Pastan
View articletitled, Treatment of Hematologic Malignancies with Immunotoxins and Antibody-Drug Conjugates
Open the PDF for in another window

Priority Reports

Regulator of G Protein Signaling 6 Mediates Doxorubicin-Induced ATM and p53 Activation by a Reactive Oxygen Species–Dependent Mechanism
Jie Huang; Jianqi Yang; Biswanath Maity; Daisuke Mayuzumi; Rory A. Fisher
View articletitled, Regulator of G Protein Signaling 6 Mediates Doxorubicin-Induced ATM and p53 Activation by a Reactive Oxygen Species–Dependent Mechanism
Supplementary data
Open the PDF for in another window
Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
Ryunosuke Kogo; Teppei Shimamura; Koshi Mimori; Kohichi Kawahara; Seiya Imoto; Tomoya Sudo; Fumiaki Tanaka; Kohei Shibata; Akira Suzuki; Shizuo Komune; Satoru Miyano; Masaki Mori
View articletitled, Long Noncoding RNA <em>HOTAIR</em> Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
Supplementary data
Open the PDF for in another window

Integrated Systems and Technologies

Evolution of Tumor Invasiveness: The Adaptive Tumor Microenvironment Landscape Model
Hyung-Ok Lee; Ariosto S. Silva; Susanna Concilio; Yue-Sheng Li; Michael Slifker; Robert A. Gatenby; Jonathan D. Cheng
View articletitled, Evolution of Tumor Invasiveness: The Adaptive Tumor Microenvironment Landscape Model
Supplementary data
Open the PDF for in another window
p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Devin T. Rosenthal; Harish Iyer; Silvia Escudero; Liwei Bao; Zhifen Wu; Alejandra C. Ventura; Celina G. Kleer; Ellen M. Arruda; Krishna Garikipati; Sofia D. Merajver
View articletitled, p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior
Supplementary data
Open the PDF for in another window
Antiangiogenic Agent Sunitinib Transiently Increases Tumor Oxygenation and Suppresses Cycling Hypoxia
Shingo Matsumoto; Sonny Batra; Keita Saito; Hironobu Yasui; Rajani Choudhuri; Chandramouli Gadisetti; Sankaran Subramanian; Nallathamby Devasahayam; Jeeva P. Munasinghe; James B. Mitchell; Murali C. Krishna
View articletitled, Antiangiogenic Agent Sunitinib Transiently Increases Tumor Oxygenation and Suppresses Cycling Hypoxia
Supplementary data
Open the PDF for in another window
Activation of the Glucocorticoid Receptor Is Associated with Poor Prognosis in Estrogen Receptor-Negative Breast Cancer
Deng Pan; Masha Kocherginsky; Suzanne D. Conzen
View articletitled, Activation of the Glucocorticoid Receptor Is Associated with Poor Prognosis in Estrogen Receptor-Negative Breast Cancer
Supplementary data
Open the PDF for in another window

Microenvironment and Immunology

Glioblastoma Angiogenesis and Tumor Cell Invasiveness Are Differentially Regulated by β8 Integrin
Jeremy H. Tchaicha; Steve B. Reyes; Jaekyung Shin; Mohammad G. Hossain; Frederick F. Lang; Joseph H. McCarty
View articletitled, Glioblastoma Angiogenesis and Tumor Cell Invasiveness Are Differentially Regulated by β8 Integrin
Supplementary data
Open the PDF for in another window
TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects
Michele Sommariva; Loris De Cecco; Michelandrea De Cesare; Lucia Sfondrini; Sylvie Ménard; Cecilia Melani; Domenico Delia; Nadia Zaffaroni; Graziella Pratesi; Valentina Uva; Elda Tagliabue; Andrea Balsari
View articletitled, TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects
Supplementary data
Open the PDF for in another window
Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer
Luc de Chaisemartin; Jérémy Goc; Diane Damotte; Pierre Validire; Pierre Magdeleinat; Marco Alifano; Isabelle Cremer; Wolf-Herman Fridman; Catherine Sautès-Fridman; Marie-Caroline Dieu-Nosjean
View articletitled, Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer
Supplementary data
Open the PDF for in another window
Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
Irina Daurkin; Evgeniy Eruslanov; Taryn Stoffs; George Q. Perrin; Chester Algood; Scott M. Gilbert; Charles J. Rosser; Li-Ming Su; Johannes Vieweg; Sergei Kusmartsev
View articletitled, Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
Supplementary data
Open the PDF for in another window
IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis
Antje Ksienzyk; Berit Neumann; Ramya Nandakumar; Katja Finsterbusch; Martina Grashoff; Rainer Zawatzky; Günter Bernhardt; Hansjörg Hauser; Andrea Kröger
View articletitled, IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis
Supplementary data
Open the PDF for in another window
Asialoglycoprotein Receptor Promotes Cancer Metastasis by Activating the EGFR–ERK Pathway
Suguru Ueno; Marija Mojic; Yoshimi Ohashi; Nobuaki Higashi; Yoshihiro Hayakawa; Tatsuro Irimura
View articletitled, Asialoglycoprotein Receptor Promotes Cancer Metastasis by Activating the EGFR–ERK Pathway
Open the PDF for in another window
Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells
Stefan Nierkens; Martijn H. den Brok; Zacharias Garcia; Susan Togher; Jori Wagenaars; Melissa Wassink; Louis Boon; Theo J. Ruers; Carl G. Figdor; Stephen P. Schoenberger; Gosse J. Adema; Edith M. Janssen
View articletitled, Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells
Open the PDF for in another window

Molecular and Cellular Pathobiology

Enhancement of TGF-β Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer
Vikas Sharma; Anna G. Antonacopoulou; Shinya Tanaka; Alexios A. Panoutsopoulos; Vasiliki Bravou; Haralabos P. Kalofonos; Vasso Episkopou
View articletitled, Enhancement of TGF-β Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer
Supplementary data
Open the PDF for in another window
miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer
Tomohiko Tsuruta; Ken-ichi Kozaki; Atsushi Uesugi; Mayuko Furuta; Akira Hirasawa; Issei Imoto; Nobuyuki Susumu; Daisuke Aoki; Johji Inazawa
View articletitled, <em>miR-152</em> Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer
Supplementary data
Open the PDF for in another window
Pivotal Role of Reduced let-7g Expression in Breast Cancer Invasion and Metastasis
Pengxu Qian; Zehua Zuo; Zhengsheng Wu; Xianyi Meng; Gaopeng Li; Zhengzhou Wu; Weijie Zhang; Sheng Tan; Vijay Pandey; Yandan Yao; Puyue Wang; Liqing Zhao; Jun Wang; Qiang Wu; Erwei Song; Peter E. Lobie; Zhinan Yin; Tao Zhu
View articletitled, Pivotal Role of Reduced <em>let-7g</em> Expression in Breast Cancer Invasion and Metastasis
Supplementary data
Open the PDF for in another window
Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Yizeng Yang; Hiroshi Nakagawa; Marie-Pier Tetreault; Janelle Billig; Noel Victor; Abha Goyal; Antonia R. Sepulveda; Jonathan P. Katz
View articletitled, Loss of Transcription Factor <em>KLF5</em> in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Supplementary data
Open the PDF for in another window
Long-lived Inflammatory Signaling in Irradiated Bone Marrow Is Genome Dependent
Sally A. Lorimore; Debayan Mukherjee; Joanne I. Robinson; Jennifer A. Chrystal; Eric G. Wright
View articletitled, Long-lived Inflammatory Signaling in Irradiated Bone Marrow Is Genome Dependent
Open the PDF for in another window

Therapeutics, Targets, and Chemical Biology

Tissue Factor–Activated Coagulation Cascade in the Tumor Microenvironment Is Critical for Tumor Progression and an Effective Target for Therapy
Yuan Liu; Pengfei Jiang; Katerina Capkova; Dong Xue; Longwu Ye; Subhash C. Sinha; Nigel Mackman; Kim D. Janda; Cheng Liu
View articletitled, Tissue Factor–Activated Coagulation Cascade in the Tumor Microenvironment Is Critical for Tumor Progression and an Effective Target for Therapy
Supplementary data
Open the PDF for in another window
Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Changmeng Cai; Sen Chen; Patrick Ng; Glenn J. Bubley; Peter S. Nelson; Elahe A. Mostaghel; Brett Marck; Alvin M. Matsumoto; Nicholas I. Simon; Hongyun Wang; Shaoyong Chen; Steven P. Balk
View articletitled, Intratumoral <em>De Novo</em> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Supplementary data
Open the PDF for in another window
Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Seok-Geun Lee; Keetae Kim; Timothy P. Kegelman; Rupesh Dash; Swadesh K. Das; Jung Kyoung Choi; Luni Emdad; Eric L. Howlett; Hyun Yong Jeon; Zhao Zhong Su; Byoung Kwon Yoo; Devanand Sarkar; Sung-Hoon Kim; Dong-Chul Kang; Paul B. Fisher
View articletitled, Oncogene <em>AEG-1</em> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary data
Open the PDF for in another window
ZNF668 Functions as a Tumor Suppressor by Regulating p53 Stability and Function in Breast Cancer
Ruozhen Hu; Guang Peng; Hui Dai; Eun-Kyoung Breuer; Katherine Stemke-Hale; Kaiyi Li; Ana M. Gonzalez-Angulo; Gordon B. Mills; Shiaw-Yih Lin
View articletitled, <em>ZNF668</em> Functions as a Tumor Suppressor by Regulating p53 Stability and Function in Breast Cancer
Supplementary data
Open the PDF for in another window

Tumor and Stem Cell Biology

Haploinsufficiency in the Prometastasis Kiss1 Receptor Gpr54 Delays Breast Tumor Initiation, Progression, and Lung Metastasis
Sung-Gook Cho; Ying Wang; Melissa Rodriguez; Kunrong Tan; Wenzheng Zhang; Jian Luo; Dali Li; Mingyao Liu
View articletitled, Haploinsufficiency in the Prometastasis Kiss1 Receptor Gpr54 Delays Breast Tumor Initiation, Progression, and Lung Metastasis
Open the PDF for in another window
A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
Rae H. Farnsworth; Tara Karnezis; Ramin Shayan; Masataka Matsumoto; Cameron J. Nowell; Marc G. Achen; Steven A. Stacker
View articletitled, A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
Supplementary data
Open the PDF for in another window

Advertisement

Email alerts

eTOC Alert
Close Modal
Breaking
Ribociclib Plus AI Greenlighted for High-Risk Breast Cancer
AACR Releases 14th Annual Cancer Progress Report
Mesothelioma Newest Approved Indication for Pembrolizumab
View more recent articles
Latest News
AMG 193 Safe, Effective in Multiple Cancer Types
STING Immune Pathway Discovery Earns Lasker Prize
Assessing New RAF-Directed Drugs in Melanoma
View more recent articles
Research Watch
Reactive Oxygen Species Drive Micronuclear Collapse in Cancer Cells
The Dynamics of Ductal Tree Remodeling Shape Mammary Field Cancerization
An Age-Associated Increase in Myelopoiesis Promotes Lung Cancer Development
View more recent articles

NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale within the United States of Bavencio® (avelumab), a pharmaceutical owned by Merck. If any resulting funds are received, they would not be used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

AACR Journals

 

 

  • Copyright © 2023 by the American Association for Cancer Research.
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept