Issues
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Vitamin D deficiency has been previously reported to be a risk factor for breast cancer progression, though whether this association represents a causal relationship is not known. In this report, human breast cancer cells are found to proliferate faster in the bone of nude mice deficient in vitamin D compared with those in vitamin D–sufficient mice. Vitamin D deficiency, predominantly through induction of increased bone resorption by osteoclasts (here highlighted by red staining for tartrate-resistant acid phosphatase activity), modifies the microenvironment of bone to enhance early breast cancer cell proliferation. For details, see the article by Ooi and colleagues on page 1835 of this issue. - PDF Icon PDF LinkTable of Contents
Cancer Research
Table of Contents
Reviews
Priority Reports
Inactivation of Junctional Adhesion Molecule-A Enhances Antitumoral Immune Response by Promoting Dendritic Cell and T Lymphocyte Infiltration
Research Articles
Integrated Systems and Technologies
miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death
Microenvironment and Immunology
A Placental Growth Factor Variant Unable to Recognize Vascular Endothelial Growth Factor (VEGF) Receptor-1 Inhibits VEGF-Dependent Tumor Angiogenesis via Heterodimerization
Molecular and Cellular Pathobiology
Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
Prevention and Epidemiology
Therapeutics, Targets, and Chemical Biology
Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer
Activation of Hedgehog Signaling by the Environmental Toxicant Arsenic May Contribute to the Etiology of Arsenic-Induced Tumors
Tumor and Stem Cell Biology
Suppression of Cyclin D1 by Hypoxia-Inducible Factor-1 via Direct Mechanism Inhibits the Proliferation and 5-Fluorouracil–Induced Apoptosis of A549 Cells
Transcriptional Profiles of CD133+ and CD133− Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin
FOXQ1 Is Overexpressed in Colorectal Cancer and Enhances Tumorigenicity and Tumor Growth
An Oncogenic Role for ETV1 in Melanoma
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer
Letters to the Editor
Corrections
Journal Archive
Cancer Research
(1941-Present; volumes 1-current)Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)
The American Journal of Cancer
(1931-1940; volumes 15-40)Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)
The Journal of Cancer Research
(1916-1930); volumes 1-14)Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)
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