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15 December 2010
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Immunofluorescence analysis of Notch4 (red) and Nodal (green) in C8161 human metastatic melanoma cells reveals the expression of these proteins in a subpopulation of these aggressive cells in culture. An anti-pan-Cadherin antibody (pink) labels the cell membrane. Cell nuclei were counterstained with DAPI (blue). For details, see the article by Hardy and colleagues on page 10340 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 0008-5472
EISSN 1538-7445
Journal Archive
Cancer Research (1941-Present; volumes 1-current)
(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.The American Journal of Cancer (1931-1940; volumes 15-40)
(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.The Journal of Cancer Research (1916-1930); volumes 1-14)
(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.Table of Contents
Breaking Advances
Reviews
Perspective
Meeting Report
Priority Reports
The Neuroblastoma-Associated F1174L ALK Mutation Causes Resistance to an ALK Kinase Inhibitor in ALK-Translocated Cancers
Takaaki Sasaki; Katsuhiro Okuda; Wei Zheng; James Butrynski; Marzia Capelletti; Liping Wang; Nathanael S. Gray; Keith Wilner; James G. Christensen; George Demetri; Geoffrey I. Shapiro; Scott J. Rodig; Michael J. Eck; Pasi A. Jänne
Integrated Systems and Technologies
Microenvironment and Immunology
The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells
Hendrik W. van Deventer; Joseph E. Burgents; Qing Ping Wu; Rita-Marie T. Woodford; W. June Brickey; Irving C. Allen; Erin McElvania-Tekippe; Jonathan S. Serody; Jenny P.-Y. Ting
CXCL12 Mediates Immunosuppression in the Lymphoma Microenvironment after Allogeneic Transplantation of Hematopoietic Cells
Christoph Dürr; Dietmar Pfeifer; Rainer Claus; Annette Schmitt-Graeff; Ulrike V. Gerlach; Ralph Graeser; Sophie Krüger; Armin Gerbitz; Robert S. Negrin; Jürgen Finke; Robert Zeiser
Molecular and Cellular Pathobiology
Therapeutics, Targets, and Chemical Biology
Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity
Gang Li; Lianglin Zhang; Enhong Chen; Jianying Wang; Xin Jiang; Jeffrey H. Chen; Grant Wickman; Karin Amundson; Simon Bergqvist; James Zobel; Dana Buckman; Sangita M. Baxi; Steven L. Bender; Gerald F. Casperson; Dana D. Hu-Lowe
Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase
Riccardo Colombo; Marina Caldarelli; Milena Mennecozzi; Maria Laura Giorgini; Francesco Sola; Paolo Cappella; Claudia Perrera; Stefania Re Depaolini; Luisa Rusconi; Ulisse Cucchi; Nilla Avanzi; Jay Aaron Bertrand; Roberto Tiberio Bossi; Enrico Pesenti; Arturo Galvani; Antonella Isacchi; Francesco Colotta; Daniele Donati; Jürgen Moll
Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes
Sarmila Majumder; Satavisha Roy; Thomas Kaffenberger; Bo Wang; Stefan Costinean; Wendy Frankel; Anna Bratasz; Periannan Kuppusamy; Tsonwin Hai; Kalpana Ghoshal; Samson T. Jacob
CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy
Adam Siddiqui-Jain; Denis Drygin; Nicole Streiner; Peter Chua; Fabrice Pierre; Sean E. O'Brien; Josh Bliesath; Mayuko Omori; Nanni Huser; Caroline Ho; Chris Proffitt; Michael K. Schwaebe; David M. Ryckman; William G. Rice; Kenna Anderes
Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process
Gatien Moriceau; Benjamin Ory; Laura Mitrofan; Chiara Riganti; Frédéric Blanchard; Régis Brion; Céline Charrier; Séverine Battaglia; Paul Pilet; Marc G. Denis; Leonard D. Shultz; Jukka Mönkkönen; Françoise Rédini; Dominique Heymann
Tumor and Stem Cell Biology
Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation
Shih-Hwa Chiou; Mong-Lien Wang; Yu-Ting Chou; Chi-Jen Chen; Chun-Fu Hong; Wang-Ju Hsieh; Hsin-Tzu Chang; Ying-Shan Chen; Tzu-Wei Lin; Han-Sui Hsu; Cheng-Wen Wu
The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Manran Liu; Toshiyuki Sakamaki; Mathew C. Casimiro; Nicole E. Willmarth; Andrew A. Quong; Xiaoming Ju; John Ojeifo; Xuanmao Jiao; Wen-Shuz Yeow; Sanjay Katiyar; L. Andrew Shirley; David Joyce; Michael P. Lisanti; Christopher Albanese; Richard G. Pestell
Retraction
Reviewers
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