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Issues

Volume 66, Issue 4
15 February 2006
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Reviews

Cancer Stem Cells: An Old Idea—A Paradigm Shift
Max S. Wicha; Suling Liu; Gabriela Dontu
View articletitled, Cancer Stem Cells: An Old Idea—A Paradigm Shift
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Identifying Cancer Stem Cells in Solid Tumors: Case Not Proven
Richard P. Hill
View articletitled, Identifying Cancer Stem Cells in Solid Tumors: Case Not Proven
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Perspectives in Cancer Research

Cancer Risk Assessment at the Atomic Level
Alvaro N.A. Monteiro; Fergus J. Couch
View articletitled, Cancer Risk Assessment at the Atomic Level
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Priority Reports

Structurally Dependent Redox Property of Ribonucleotide Reductase Subunit p53R2
Lijun Xue; Bingsen Zhou; Xiyong Liu; Tieli Wang; Jennifer Shih; Christina Qi; Yvonne Heung; Yun Yen
View articletitled, Structurally Dependent Redox Property of Ribonucleotide Reductase Subunit p53R2
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The Novel Tumor Suppressor p33ING2 Enhances Nucleotide Excision Repair via Inducement of Histone H4 Acetylation and Chromatin Relaxation
Jing Wang; Mei Yieng Chin; Gang Li
View articletitled, The Novel Tumor Suppressor p33ING2 Enhances Nucleotide Excision Repair via Inducement of Histone H4 Acetylation and Chromatin Relaxation
Supplementary data
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Ex vivo Detectable Human CD8 T-Cell Responses to Cancer-Testis Antigens
Petra Baumgaertner; Nathalie Rufer; Estelle Devevre; Laurent Derre; Donata Rimoldi; Christine Geldhof; Verena Voelter; Danielle Liénard; Pedro Romero; Daniel E. Speiser
View articletitled, <em>Ex vivo</em> Detectable Human CD8 T-Cell Responses to Cancer-Testis Antigens
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The Metastasis-Associated Gene CD24 Is Regulated by Ral GTPase and Is a Mediator of Cell Proliferation and Survival in Human Cancer
Steven C. Smith; Gary Oxford; Zhong Wu; Matthew D. Nitz; Mark Conaway; Henry F. Frierson; Garret Hampton; Dan Theodorescu
View articletitled, The Metastasis-Associated Gene <em>CD24</em> Is Regulated by Ral GTPase and Is a Mediator of Cell Proliferation and Survival in Human Cancer
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Molecular Biology, Pathobiology, and Genetics

Mammary Tumorigenesis following Transgenic Expression of a Dominant Negative CHK2 Mutant
Eunice L. Kwak; Sang Kim; Jianmin Zhang; Robert D. Cardiff; Emmett V. Schmidt; Daniel A. Haber
View articletitled, Mammary Tumorigenesis following Transgenic Expression of a Dominant Negative CHK2 Mutant
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Pten Deficiency Activates Distinct Downstream Signaling Pathways in a Tissue-Specific Manner
Lina I. Yoo; David W. Liu; Sandrine Le Vu; Roderick T. Bronson; Hong Wu; Junying Yuan
View articletitled, <em>Pten</em> Deficiency Activates Distinct Downstream Signaling Pathways in a Tissue-Specific Manner
Supplementary data
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Soluble IGF2 Receptor Rescues ApcMin/+ Intestinal Adenoma Progression Induced by Igf2 Loss of Imprinting
James Harper; Jason L. Burns; Emily J. Foulstone; Massimo Pignatelli; Silvio Zaina; A. Bassim Hassan
View articletitled, Soluble IGF2 Receptor Rescues <em>Apc</em><sup><em>Min/</em>+</sup> Intestinal Adenoma Progression Induced by <em>Igf2</em> Loss of Imprinting
Supplementary data
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Identification of the IFITM Family as a New Molecular Marker in Human Colorectal Tumors
Pauline Andreu; Sabine Colnot; Cécile Godard; Pierre Laurent-Puig; Dominique Lamarque; Axel Kahn; Christine Perret; Béatrice Romagnolo
View articletitled, Identification of the <em>IFITM</em> Family as a New Molecular Marker in Human Colorectal Tumors
Supplementary data
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A Gene Expression Signature that Can Predict Green Tea Exposure and Chemopreventive Efficacy of Lung Cancer in Mice
Yan Lu; Ruisheng Yao; Ying Yan; Yian Wang; Yukihiko Hara; Ronald A. Lubet; Ming You
View articletitled, A Gene Expression Signature that Can Predict Green Tea Exposure and Chemopreventive Efficacy of Lung Cancer in Mice
Supplementary data
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Dominant-Stable β-Catenin Expression Causes Cell Fate Alterations and Wnt Signaling Antagonist Expression in a Murine Granulosa Cell Tumor Model
Derek Boerboom; Lisa D. White; Sophie Dalle; José Courty; JoAnne S. Richards
View articletitled, Dominant-Stable β-Catenin Expression Causes Cell Fate Alterations and Wnt Signaling Antagonist Expression in a Murine Granulosa Cell Tumor Model
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Ras and Its Signals Diffuse through the Cell on Randomly Moving Nanoparticles
Barak Rotblat; Ofer Yizhar; Roni Haklai; Uri Ashery; Yoel Kloog
View articletitled, Ras and Its Signals Diffuse through the Cell on Randomly Moving Nanoparticles
Supplementary data
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The Homeoprotein Six1 Transcriptionally Activates Multiple Protumorigenic Genes but Requires Ezrin to Promote Metastasis
Yanlin Yu; Elai Davicioni; Timothy J. Triche; Glenn Merlino
View articletitled, The Homeoprotein Six1 Transcriptionally Activates Multiple Protumorigenic Genes but Requires Ezrin to Promote Metastasis
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Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays
Chunxia Li; Mitsuo Kato; Lily Shiue; John E. Shively; Manuel Ares, Jr.; Ren-Jang Lin
View articletitled, Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays
Supplementary data
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Genetic and Epigenetic Analysis of von Hippel-Lindau (VHL) Gene Alterations and Relationship with Clinical Variables in Sporadic Renal Cancer
Rosamonde E. Banks; Prasanna Tirukonda; Claire Taylor; Nick Hornigold; Dewi Astuti; Dena Cohen; Eamonn R. Maher; Anthea J. Stanley; Patricia Harnden; Adrian Joyce; Margaret Knowles; Peter J. Selby
View articletitled, Genetic and Epigenetic Analysis of von Hippel-Lindau (<em>VHL</em>) Gene Alterations and Relationship with Clinical Variables in Sporadic Renal Cancer
Supplementary data
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BRCA1 DNA-Binding Activity Is Stimulated by BARD1
Amanda M. Simons; Andrew A. Horwitz; Lea M. Starita; Karen Griffin; R. Scott Williams; J.N. Mark Glover; Jeffrey D. Parvin
View articletitled, BRCA1 DNA-Binding Activity Is Stimulated by BARD1
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Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variants of Unknown Clinical Significance
Georgia Chenevix-Trench; Sue Healey; Sunil Lakhani; Paul Waring; Margaret Cummings; Ross Brinkworth; Amie M. Deffenbaugh; Lynn Anne Burbidge; Dmitry Pruss; Thad Judkins; Tom Scholl; Anna Bekessy; Anna Marsh; Paul Lovelock; Ming Wong; Andrea Tesoriero; Helene Renard; Melissa Southey; John L. Hopper; Koulis Yannoukakos; Melissa Brown; kConFab Investigators; Douglas Easton; Sean V. Tavtigian; David Goldgar; Amanda B. Spurdle
View articletitled, Genetic and Histopathologic Evaluation of <em>BRCA1</em> and <em>BRCA2</em> DNA Sequence Variants of Unknown Clinical Significance
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Cell, Tumor, and Stem Cell Biology

ErbB2 Increases Vascular Endothelial Growth Factor Protein Synthesis via Activation of Mammalian Target of Rapamycin/p70S6K Leading to Increased Angiogenesis and Spontaneous Metastasis of Human Breast Cancer Cells
Kristine S. Klos; Shannon L. Wyszomierski; Menghong Sun; Ming Tan; Xiaoyan Zhou; Ping Li; Wentao Yang; Guosheng Yin; Walter N. Hittelman; Dihua Yu
View articletitled, ErbB2 Increases Vascular Endothelial Growth Factor Protein Synthesis via Activation of Mammalian Target of Rapamycin/p70S6K Leading to Increased Angiogenesis and Spontaneous Metastasis of Human Breast Cancer Cells
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Differential Role of Transient Receptor Potential Channels in Ca2+ Entry and Proliferation of Prostate Cancer Epithelial Cells
Stephanie Thebault; Matthieu Flourakis; Karine Vanoverberghe; Franck Vandermoere; Morad Roudbaraki; V'yacheslav Lehen'kyi; Christian Slomianny; Benjamin Beck; Pascal Mariot; Jean-Louis Bonnal; Brigitte Mauroy; Yaroslav Shuba; Thierry Capiod; Roman Skryma; Natalia Prevarskaya
View articletitled, Differential Role of Transient Receptor Potential Channels in Ca<sup>2+</sup> Entry and Proliferation of Prostate Cancer Epithelial Cells
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Sprouty 2, an Inhibitor of Mitogen-Activated Protein Kinase Signaling, Is Down-Regulated in Hepatocellular Carcinoma
Chee Wai Fong; Mei-Sze Chua; Arthur B. McKie; Sharon Hee Ming Ling; Veronica Mason; Rui Li; Permeen Yusoff; Ting Ling Lo; Hing Y. Leung; Samuel K.S. So; Graeme R. Guy
View articletitled, Sprouty 2, an Inhibitor of Mitogen-Activated Protein Kinase Signaling, Is Down-Regulated in Hepatocellular Carcinoma
Supplementary data
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Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development
Erich Koller; Stephanie Propp; Hong Zhang; Chenguang Zhao; Xiaokun Xiao; MingYi Chang; Scott A. Hirsch; Peter J. Shepard; Seongjoon Koo; Cain Murphy; Robert I. Glazer; Nicholas M. Dean
View articletitled, Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development
Supplementary data
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Stimulation of Cyclooxygenase-2 Expression by Bone-Derived Transforming Growth Factor-β Enhances Bone Metastases in Breast Cancer
Toru Hiraga; Akira Myoui; Mary E. Choi; Hideki Yoshikawa; Toshiyuki Yoneda
View articletitled, Stimulation of Cyclooxygenase-2 Expression by Bone-Derived Transforming Growth Factor-β Enhances Bone Metastases in Breast Cancer
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Effects of the Vascular Disrupting Agent ZD6126 on Interstitial Fluid Pressure and Cell Survival in Tumors
Julia V. Skliarenko; Sarah Jane Lunt; Maggie L. Gordon; Alex Vitkin; Michael Milosevic; Richard P. Hill
View articletitled, Effects of the Vascular Disrupting Agent ZD6126 on Interstitial Fluid Pressure and Cell Survival in Tumors
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Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
Christelle Adolphe; Rehan Hetherington; Tammy Ellis; Brandon Wainwright
View articletitled, Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
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Minimal Active Domain and Mechanism of Action of the Angiogenesis Inhibitor Histidine-Rich Glycoprotein
Johan Dixelius; Anna-Karin Olsson; Åsa Thulin; Chunsik Lee; Irja Johansson; Lena Claesson-Welsh
View articletitled, Minimal Active Domain and Mechanism of Action of the Angiogenesis Inhibitor Histidine-Rich Glycoprotein
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Induction of Centrosome Amplification during Arsenite-Induced Mitotic Arrest in CGL-2 Cells
Ling-Huei Yih; Yun-Yu Tseng; Yi-Chen Wu; Te-Chang Lee
View articletitled, Induction of Centrosome Amplification during Arsenite-Induced Mitotic Arrest in CGL-2 Cells
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Genistein Represses Telomerase Activity via Both Transcriptional and Posttranslational Mechanisms in Human Prostate Cancer Cells
Shankar Jagadeesh; Satoru Kyo; Partha P. Banerjee
View articletitled, Genistein Represses Telomerase Activity via Both Transcriptional and Posttranslational Mechanisms in Human Prostate Cancer Cells
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Multiple Oncogenic Changes (K-RASV12, p53 Knockdown, Mutant EGFRs, p16 Bypass, Telomerase) Are Not Sufficient to Confer a Full Malignant Phenotype on Human Bronchial Epithelial Cells
Mitsuo Sato; Melville B. Vaughan; Luc Girard; Michael Peyton; Woochang Lee; David S. Shames; Ruben D. Ramirez; Noriaki Sunaga; Adi F. Gazdar; Jerry W. Shay; John D. Minna
View articletitled, Multiple Oncogenic Changes (<em>K-RAS<sup>V12</sup></em>, p53 Knockdown, <em>Mutant EGFRs, p16</em> Bypass, Telomerase) Are Not Sufficient to Confer a Full Malignant Phenotype on Human Bronchial Epithelial Cells
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Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer
Dafna Tsafrir; Manny Bacolod; Zachariah Selvanayagam; Ilan Tsafrir; Jinru Shia; Zhaoshi Zeng; Hao Liu; Curtis Krier; Robert F. Stengel; Francis Barany; William L. Gerald; Philip B. Paty; Eytan Domany; Daniel A. Notterman
View articletitled, Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer
Supplementary data
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Increased Frequency of Aberrations in the p53/MDM2/p14ARF Pathway in Neuroblastoma Cell Lines Established at Relapse
Jane Carr; Emma Bell; Andrew D.J. Pearson; Ursula R. Kees; Helen Beris; John Lunec; Deborah A. Tweddle
View articletitled, Increased Frequency of Aberrations in the p53/MDM2/p14<sup><em>ARF</em></sup> Pathway in Neuroblastoma Cell Lines Established at Relapse
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Integrin α4β1 Promotes Monocyte Trafficking and Angiogenesis in Tumors
Hui Jin; Jingmei Su; Barbara Garmy-Susini; Jeanine Kleeman; Judy Varner
View articletitled, Integrin α<sub>4</sub>β<sub>1</sub> Promotes Monocyte Trafficking and Angiogenesis in Tumors
Supplementary data
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The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer
Il-Man Kim; Timothy Ackerson; Sneha Ramakrishna; Maria Tretiakova; I-Ching Wang; Tanya V. Kalin; Michael L. Major; Galina A. Gusarova; Helena M. Yoder; Robert H. Costa; Vladimir V. Kalinichenko
View articletitled, The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer
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Reduction of Cytosolic p27Kip1 Inhibits Cancer Cell Motility, Survival, and Tumorigenicity
Frederick Y. Wu; Shizhen Emily Wang; Melinda E. Sanders; Incheol Shin; Federico Rojo; Jose Baselga; Carlos L. Arteaga
View articletitled, Reduction of Cytosolic p27<sup>Kip1</sup> Inhibits Cancer Cell Motility, Survival, and Tumorigenicity
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Tumor Endothelial Cells Express Epidermal Growth Factor Receptor (EGFR) but not ErbB3 and Are Responsive to EGF and to EGFR Kinase Inhibitors
Dhara N. Amin; Kyoko Hida; Diane R. Bielenberg; Michael Klagsbrun
View articletitled, Tumor Endothelial Cells Express Epidermal Growth Factor Receptor (EGFR) but not ErbB3 and Are Responsive to EGF and to EGFR Kinase Inhibitors
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Role of the CXCL12/CXCR4 Axis in Peritoneal Carcinomatosis of Gastric Cancer
Kazuo Yasumoto; Keiichi Koizumi; Atsuhiro Kawashima; Yurika Saitoh; Yoshihisa Arita; Kanna Shinohara; Takayuki Minami; Takashi Nakayama; Hiroaki Sakurai; Yutaka Takahashi; Osamu Yoshie; Ikuo Saiki
View articletitled, Role of the CXCL12/CXCR4 Axis in Peritoneal Carcinomatosis of Gastric Cancer
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Cooperation between FGF8b Overexpression and PTEN Deficiency in Prostate Tumorigenesis
Chen Zhong; Gohar Saribekyan; Chun-Peng Liao; Michael B. Cohen; Pradip Roy-Burman
View articletitled, Cooperation between FGF8b Overexpression and PTEN Deficiency in Prostate Tumorigenesis
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Runx2 and MYC Collaborate in Lymphoma Development by Suppressing Apoptotic and Growth Arrest Pathways In vivo
Karen Blyth; François Vaillant; Linda Hanlon; Nancy Mackay; Margaret Bell; Alma Jenkins; James C. Neil; Ewan R. Cameron
View articletitled, <em>Runx2</em> and <em>MYC</em> Collaborate in Lymphoma Development by Suppressing Apoptotic and Growth Arrest Pathways <em>In vivo</em>
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The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Martine Deckers; Maarten van Dinther; Jeroen Buijs; Ivo Que; Clemens Löwik; Gabri van der Pluijm; Peter ten Dijke
View articletitled, The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Supplementary data
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Enhanced Sensitivity to Cytochrome c–Induced Apoptosis Mediated by PHAPI in Breast Cancer Cells
Zachary T. Schafer; Amanda B. Parrish; Kevin M. Wright; Seth S. Margolis; Jeffrey R. Marks; Mohanish Deshmukh; Sally Kornbluth
View articletitled, Enhanced Sensitivity to Cytochrome <em>c</em>–Induced Apoptosis Mediated by PHAPI in Breast Cancer Cells
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Direct Demonstration of Instabilities in Oxygen Concentrations within the Extravascular Compartment of an Experimental Tumor
Jennifer Lanzen; Rod D. Braun; Bruce Klitzman; David Brizel; Timothy W. Secomb; Mark W. Dewhirst
View articletitled, Direct Demonstration of Instabilities in Oxygen Concentrations within the Extravascular Compartment of an Experimental Tumor
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The Ligand Status of the Aromatic Hydrocarbon Receptor Modulates Transcriptional Activation of BRCA-1 Promoter by Estrogen
Jennifer K. Hockings; Patricia A. Thorne; Michael Q. Kemp; Sherif S. Morgan; Ornella Selmin; Donato F. Romagnolo
View articletitled, The Ligand Status of the Aromatic Hydrocarbon Receptor Modulates Transcriptional Activation of BRCA-1 Promoter by Estrogen
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Stalled Replication Induces p53 Accumulation through Distinct Mechanisms from DNA Damage Checkpoint Pathways
Chui Chui Ho; Wai Yi Siu; Anita Lau; Wan Mui Chan; Talha Arooz; Randy Y.C. Poon
View articletitled, Stalled Replication Induces p53 Accumulation through Distinct Mechanisms from DNA Damage Checkpoint Pathways
Supplementary data
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Role of Protein Kinase CK2 in the Regulation of Tumor Necrosis Factor–Related Apoptosis Inducing Ligand–Induced Apoptosis in Prostate Cancer Cells
Guixia Wang; Kashif A. Ahmad; Khalil Ahmed
View articletitled, Role of Protein Kinase CK2 in the Regulation of Tumor Necrosis Factor–Related Apoptosis Inducing Ligand–Induced Apoptosis in Prostate Cancer Cells
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Parathyroid Hormone–Related Protein Localization in Breast Cancers Predict Improved Prognosis
Michael A. Henderson; Janine A. Danks; John L. Slavin; Graham B. Byrnes; Peter F.M. Choong; John B. Spillane; John L. Hopper; T. John Martin
View articletitled, Parathyroid Hormone–Related Protein Localization in Breast Cancers Predict Improved Prognosis
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Xanthine Oxidase–Dependent Regulation of Hypoxia-Inducible Factor in Cancer Cells
Corinne E. Griguer; Claudia R. Oliva; Eric E. Kelley; Gregory I. Giles; Jack R. Lancaster, Jr.; G. Yancey Gillespie
View articletitled, Xanthine Oxidase–Dependent Regulation of Hypoxia-Inducible Factor in Cancer Cells
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The p38 Kinases MKK4 and MKK6 Suppress Metastatic Colonization in Human Ovarian Carcinoma
Jonathan A. Hickson; Dezheng Huo; Donald J. Vander Griend; Anning Lin; Carrie W. Rinker-Schaeffer; S. Diane Yamada
View articletitled, The p38 Kinases MKK4 and MKK6 Suppress Metastatic Colonization in Human Ovarian Carcinoma
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Targeting of the Receptor Protein Tyrosine Phosphatase β with a Monoclonal Antibody Delays Tumor Growth in a Glioblastoma Model
Erik D. Foehr; Gustavo Lorente; Jane Kuo; Rosie Ram; Karoly Nikolich; Roman Urfer
View articletitled, Targeting of the Receptor Protein Tyrosine Phosphatase β with a Monoclonal Antibody Delays Tumor Growth in a Glioblastoma Model
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SKI-606 Decreases Growth and Motility of Colorectal Cancer Cells by Preventing pp60(c-Src)–Dependent Tyrosine Phosphorylation of β-Catenin and Its Nuclear Signaling
Addolorata Maria Luce Coluccia; Daniela Benati; Hafedh Dekhil; Annamaria De Filippo; Cathy Lan; Carlo Gambacorti-Passerini
View articletitled, SKI-606 Decreases Growth and Motility of Colorectal Cancer Cells by Preventing pp60(c-Src)–Dependent Tyrosine Phosphorylation of β-Catenin and Its Nuclear Signaling
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α-Sulfoquinovosylmonoacylglycerol Is a Novel Potent Radiosensitizer Targeting Tumor Angiogenesis
Ippei Sakimoto; Keisuke Ohta; Takayuki Yamazaki; Seiji Ohtani; Hiroeki Sahara; Fumio Sugawara; Kengo Sakaguchi; Masahiko Miura
View articletitled, α-Sulfoquinovosylmonoacylglycerol Is a Novel Potent Radiosensitizer Targeting Tumor Angiogenesis
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Expression of p53 Enhances Selenite-Induced Superoxide Production and Apoptosis in Human Prostate Cancer Cells
Rui Zhao; Nong Xiang; Frederick E. Domann; Weixiong Zhong
View articletitled, Expression of p53 Enhances Selenite-Induced Superoxide Production and Apoptosis in Human Prostate Cancer Cells
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Mechanism by Which Mammalian Target of Rapamycin Inhibitors Sensitize Multiple Myeloma Cells to Dexamethasone-Induced Apoptosis
Huajun Yan; Patrick Frost; Yijiang Shi; Bao Hoang; Sanjai Sharma; Myrna Fisher; Joseph Gera; Alan Lichtenstein
View articletitled, Mechanism by Which Mammalian Target of Rapamycin Inhibitors Sensitize Multiple Myeloma Cells to Dexamethasone-Induced Apoptosis
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Glioma Virotherapy: Effects of Innate Immune Suppression and Increased Viral Replication Capacity
Avner Friedman; Jianjun Paul Tian; Giulia Fulci; E. Antonio Chiocca; Jin Wang
View articletitled, Glioma Virotherapy: Effects of Innate Immune Suppression and Increased Viral Replication Capacity
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Protein Kinase B/Akt-Dependent Phosphorylation of Glycogen Synthase Kinase-3β in Irradiated Vascular Endothelium
Jiahua Tan; Ling Geng; Eugenia M. Yazlovitskaya; Dennis E. Hallahan
View articletitled, Protein Kinase B/Akt-Dependent Phosphorylation of Glycogen Synthase Kinase-3β in Irradiated Vascular Endothelium
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Lymphocyte Activation Antigen CD70 Expressed by Renal Cell Carcinoma Is a Potential Therapeutic Target for Anti-CD70 Antibody-Drug Conjugates
Che-Leung Law; Kristine A. Gordon; Brian E. Toki; Andrew K. Yamane; Michelle A. Hering; Charles G. Cerveny; Joseph M. Petroziello; Maureen C. Ryan; Leia Smith; Ronald Simon; Guido Sauter; Ezogelin Oflazoglu; Svetlana O. Doronina; Damon L. Meyer; Joseph A. Francisco; Paul Carter; Peter D. Senter; John A. Copland; Christopher G. Wood; Alan F. Wahl
View articletitled, Lymphocyte Activation Antigen CD70 Expressed by Renal Cell Carcinoma Is a Potential Therapeutic Target for Anti-CD70 Antibody-Drug Conjugates
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Cell Adhesion to Fibronectin (CAM-DR) Influences Acquired Mitoxantrone Resistance in U937 Cells
Lori A. Hazlehurst; Raul F. Argilagos; Michael Emmons; David Boulware; Craig A. Beam; Dan M. Sullivan; William S. Dalton
View articletitled, Cell Adhesion to Fibronectin (CAM-DR) Influences Acquired Mitoxantrone Resistance in U937 Cells
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Endocytic Recycling Compartments Altered in Cisplatin-Resistant Cancer Cells
Xing-Jie Liang; Sushmita Mukherjee; Ding-Wu Shen; Frederick R. Maxfield; Michael M. Gottesman
View articletitled, Endocytic Recycling Compartments Altered in Cisplatin-Resistant Cancer Cells
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Regression of Melanoma in a Murine Model by RLIP76 Depletion
Sharad S. Singhal; Yogesh C. Awasthi; Sanjay Awasthi
View articletitled, Regression of Melanoma in a Murine Model by RLIP76 Depletion
Supplementary data
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Multiple Robust Signatures for Detecting Lymph Node Metastasis in Head and Neck Cancer
Paul Roepman; Patrick Kemmeren; Lodewijk F.A. Wessels; Piet J. Slootweg; Frank C.P. Holstege
View articletitled, Multiple Robust Signatures for Detecting Lymph Node Metastasis in Head and Neck Cancer
Supplementary data
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Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors
Aaron D. Schimmer; Michael P. Thomas; Rose Hurren; Marcela Gronda; Maurizio Pellecchia; Gregory R. Pond; Marina Konopleva; Debbie Gurfinkel; Imtiaz A. Mawji; Ewan Brown; John C. Reed
View articletitled, Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors
Supplementary data
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Activating Transcription Factor 3 and Early Growth Response 1 Are the Novel Targets of LY294002 in a Phosphatidylinositol 3-Kinase–Independent Pathway
Kiyoshi Yamaguchi; Seong-Ho Lee; Jong-Sik Kim; Jay Wimalasena; Shigetaka Kitajima; Seung Joon Baek
View articletitled, Activating Transcription Factor 3 and Early Growth Response 1 Are the Novel Targets of LY294002 in a Phosphatidylinositol 3-Kinase–Independent Pathway
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C-fos Assessment as a Marker of Anti–Epidermal Growth Factor Receptor Effect
Antonio Jimeno; Peter Kulesza; Erik Kincaid; Nadia Bouaroud; Audrey Chan; Arlene Forastiere; Julie Brahmer; Douglas P. Clark; Manuel Hidalgo
View articletitled, <em>C-fos</em> Assessment as a Marker of Anti–Epidermal Growth Factor Receptor Effect
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Down-regulation of Insulin Receptor by Antibodies against the Type I Insulin-Like Growth Factor Receptor: Implications for Anti–Insulin-Like Growth Factor Therapy in Breast Cancer
Deepali Sachdev; Rajeeva Singh; Yoko Fujita-Yamaguchi; Douglas Yee
View articletitled, Down-regulation of Insulin Receptor by Antibodies against the Type I Insulin-Like Growth Factor Receptor: Implications for Anti–Insulin-Like Growth Factor Therapy in Breast Cancer
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Molecular Target-Based Therapy of Pancreatic Cancer
Irina V. Lebedeva; Devanand Sarkar; Zao-Zhong Su; Rahul V. Gopalkrishnan; Mohammad Athar; Aaron Randolph; Kristoffer Valerie; Paul Dent; Paul B. Fisher
View articletitled, Molecular Target-Based Therapy of Pancreatic Cancer
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Immunology

Embryonic Stem Cell–Derived Dendritic Cells Expressing Glypican-3, a Recently Identified Oncofetal Antigen, Induce Protective Immunity against Highly Metastatic Mouse Melanoma, B16-F10
Yutaka Motomura; Satoru Senju; Tetsuya Nakatsura; Hidetake Matsuyoshi; Shinya Hirata; Mikio Monji; Hiroyuki Komori; Daiki Fukuma; Hideo Baba; Yasuharu Nishimura
View articletitled, Embryonic Stem Cell–Derived Dendritic Cells Expressing Glypican-3, a Recently Identified Oncofetal Antigen, Induce Protective Immunity against Highly Metastatic Mouse Melanoma, B16-F10
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Melanosomal Targeting Sequences from gp100 Are Essential for MHC Class II–Restricted Endogenous Epitope Presentation and Mobilization to Endosomal Compartments
Stéphanie Lepage; Réjean Lapointe
View articletitled, Melanosomal Targeting Sequences from gp100 Are Essential for MHC Class II–Restricted Endogenous Epitope Presentation and Mobilization to Endosomal Compartments
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Multiple Hepatic Receptors Cooperate to Eliminate Secretory Mucins Aberrantly Entering the Bloodstream: Are Circulating Cancer Mucins the “Tip of the Iceberg”?
Mark G. Wahrenbrock; Ajit Varki
View articletitled, Multiple Hepatic Receptors Cooperate to Eliminate Secretory Mucins Aberrantly Entering the Bloodstream: Are Circulating Cancer Mucins the “Tip of the Iceberg”?
Supplementary data
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Low Surface Expression of B7-1 (CD80) Is an Immunoescape Mechanism of Colon Carcinoma
Iñigo Tirapu; Eduardo Huarte; Cristiana Guiducci; Ainhoa Arina; Mikel Zaratiegui; Oihana Murillo; Alvaro Gonzalez; Carmen Berasain; Pedro Berraondo; Puri Fortes; Jesús Prieto; Mario P. Colombo; Lieping Chen; Ignacio Melero
View articletitled, Low Surface Expression of B7-1 (CD80) Is an Immunoescape Mechanism of Colon Carcinoma
Supplementary data
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p53 Regulates Cellular Resistance to Complement Lysis through Enhanced Expression of CD59
Rossen M. Donev; Duncan S. Cole; Baalasubramanian Sivasankar; Timothy R. Hughes; B. Paul Morgan
View articletitled, p53 Regulates Cellular Resistance to Complement Lysis through Enhanced Expression of CD59
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Endocrinology

3-Methylcholanthrene and Other Aryl Hydrocarbon Receptor Agonists Directly Activate Estrogen Receptor α
Maen Abdelrahim; Eric Ariazi; Kyounghyun Kim; Shaheen Khan; Rola Barhoumi; Robert Burghardt; Shengxi Liu; Denise Hill; Richard Finnell; Bogdan Wlodarczyk; V. Craig Jordan; Stephen Safe
View articletitled, 3-Methylcholanthrene and Other Aryl Hydrocarbon Receptor Agonists Directly Activate Estrogen Receptor α
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Epidemiology and Prevention

Haplotype Analysis of the HSD17B1 Gene and Risk of Breast Cancer: A Comprehensive Approach to Multicenter Analyses of Prospective Cohort Studies
Heather Spencer Feigelson; David G. Cox; Howard M. Cann; Sholom Wacholder; Rudolf Kaaks; Brian E. Henderson; Demetrius Albanes; David Altshuler; Goran Berglund; Franco Berrino; Sheila Bingham; Julie E. Buring; Noel P. Burtt; Eugenia E. Calle; Stephen J. Chanock; Francoise Clavel-Chapelon; Graham Colditz; W. Ryan Diver; Matthew L. Freedman; Christopher A. Haiman; Susan E. Hankinson; Richard B. Hayes; Joel N. Hirschhorn; David Hunter; Laurence N. Kolonel; Peter Kraft; Loic LeMarchand; Jakob Linseisen; William Modi; Carmen Navarro; Petra H. Peeters; Malcolm C. Pike; Elio Riboli; V. Wendy Setiawan; Daniel O. Stram; Gilles Thomas; Michael J. Thun; Anne Tjonneland; Dimitrios Trichopoulos
View articletitled, Haplotype Analysis of the <em>HSD17B1</em> Gene and Risk of Breast Cancer: A Comprehensive Approach to Multicenter Analyses of Prospective Cohort Studies
Supplementary data
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Association between Plasma Prolactin Concentrations and Risk of Breast Cancer among Predominately Premenopausal Women
Shelley S. Tworoger; Patrick Sluss; Susan E. Hankinson
View articletitled, Association between Plasma Prolactin Concentrations and Risk of Breast Cancer among Predominately Premenopausal Women
Supplementary data
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A Prospective Study of Serum C-Reactive Protein and Colorectal Cancer Risk in Men
Marc J. Gunter; Rachael Stolzenberg-Solomon; Amanda J. Cross; Michael F. Leitzmann; Stephanie Weinstein; Richard J. Wood; Jarmo Virtamo; Philip R. Taylor; Demetrius Albanes; Rashmi Sinha
View articletitled, A Prospective Study of Serum C-Reactive Protein and Colorectal Cancer Risk in Men
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Potent Protection against Aflatoxin-Induced Tumorigenesis through Induction of Nrf2-Regulated Pathways by the Triterpenoid 1-[2-Cyano-3-,12-Dioxooleana-1,9(11)-Dien-28-Oyl]Imidazole
Melinda S. Yates; Mi-Kyoung Kwak; Patricia A. Egner; John D. Groopman; Sridevi Bodreddigari; Thomas R. Sutter; Karen J. Baumgartner; B.D. Roebuck; Karen T. Liby; Mark M. Yore; Tadashi Honda; Gordon W. Gribble; Michael B. Sporn; Thomas W. Kensler
View articletitled, Potent Protection against Aflatoxin-Induced Tumorigenesis through Induction of Nrf2-Regulated Pathways by the Triterpenoid 1-[2-Cyano-3-,12-Dioxooleana-1,9(11)-Dien-28-Oyl]Imidazole
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Correction

Antilymphoma Activity of an Anti-CD40 Antibody
View articletitled, Antilymphoma Activity of an Anti-CD40 Antibody
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