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Issues

Volume 66, Issue 2
15 January 2006
Cancer Research Cover Image for Volume 66, Issue 2
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Reviews

Cranking the Immunologic Engine with Chemotherapy: Using Context to Drive Tumor Antigen Cross-Presentation towards Useful Antitumor Immunity
Robbert G. van der Most; Andrew Currie; Bruce W.S. Robinson; Richard A. Lake
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Distinct Role of Macrophages in Different Tumor Microenvironments
Claire E. Lewis; Jeffrey W. Pollard
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Priority Reports

Combined Inhibitory Effects of Curcumin and Phenethyl Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in Immunodeficient Mice
Tin Oo Khor; Young-Sam Keum; Wen Lin; Jung-Hwan Kim; Rong Hu; Guoxiang Shen; Changjiang Xu; Avanthika Gopalakrishnan; Bandaru Reddy; Xi Zheng; Allan H. Conney; Ah-Ng Tony Kong
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Significance of Murine Retroviral Mutagenesis for Identification of Disease Genes in Human Acute Myeloid Leukemia
Stefan J. Erkeland; Roel G.W. Verhaak; Peter J.M. Valk; Ruud Delwel; Bob Löwenberg; Ivo P. Touw
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HIV-1 Vpr Induces DNA Double-Strand Breaks
Hiroaki Tachiwana; Mari Shimura; Chikako Nakai-Murakami; Kenzo Tokunaga; Yoshimasa Takizawa; Tetsutaro Sata; Hitoshi Kurumizaka; Yukihito Ishizaka
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Comparison of Metabolic Pathways between Cancer Cells and Stromal Cells in Colorectal Carcinomas: a Metabolic Survival Role for Tumor-Associated Stroma
Michael I. Koukourakis; Alexandra Giatromanolaki; Adrian L. Harris; Efthimios Sivridis
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Ductal Access for Prevention and Therapy of Mammary Tumors
Satoshi Murata; Scott L. Kominsky; Mustafa Vali; Zhe Zhang; Elizabeth Garrett-Mayer; Dorian Korz; David Huso; Sharyn D. Baker; James Barber; Elizabeth Jaffee; R. Todd Reilly; Saraswati Sukumar
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The Single Nucleotide Polymorphism IVS1+309 in Mouse Double Minute 2 Does Not Affect Risk of Familial Breast Cancer
Stefan Wilkening; Justo Lorenzo Bermejo; Barbara Burwinkel; Rüdiger Klaes; Claus R. Bartram; Alfons Meindl; Peter Bugert; Rita K. Schmutzler; Barbara Wappenschmidt; Michael Untch; Kari Hemminki; Asta Försti
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Tumor Cell Lines Expressing the Proteasome Subunit Isoform LMP7E1 Exhibit Immunoproteasome Deficiency
Sylvia Heink; Benjamin Fricke; Daniela Ludwig; Peter-M. Kloetzel; Elke Krüger
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CpG Island Methylation and Expression of the Secreted Frizzled-Related Protein Gene Family in Chronic Lymphocytic Leukemia
Te-Hui Liu; Aparna Raval; Shih-Shih Chen; Jennifer J. Matkovic; John C. Byrd; Christoph Plass
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Gene Conversion Is a Frequent Mechanism of Inactivation of the Wild-Type Allele in Cancers from MLH1/MSH2 Deletion Carriers
Jian Zhang; Annette Lindroos; Saara Ollila; Anna Russell; Giancarlo Marra; Hansjakob Mueller; Paivi Peltomaki; Martina Plasilova; Karl Heinimann
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Molecular Biology, Pathobiology, and Genetics

PEG10 Is a c-MYC Target Gene in Cancer Cells
Chi-Ming Li; Adam A. Margolin; Martha Salas; Lorenzo Memeo; Mahesh Mansukhani; Hanina Hibshoosh; Matthias Szabolcs; Apostolos Klinakis; Benjamin Tycko
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c-Myc Overexpression Causes Anaplasia in Medulloblastoma
Duncan Stearns; Aneeka Chaudhry; Ty W. Abel; Peter C. Burger; Chi V. Dang; Charles G. Eberhart
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De novo CpG Island Methylation in Human Cancer Cells
Kam-Wing Jair; Kurtis E. Bachman; Hiromu Suzuki; Angela H. Ting; Ina Rhee; Ray-Whay Chiu Yen; Stephen B. Baylin; Kornel E. Schuebel
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A Functional Variant in the Transcriptional Regulatory Region of Gene LOC344967 Cosegregates with Disease Phenotype in Familial Nasopharyngeal Carcinoma
Ri-Cheng Jiang; Hai-De Qin; Mu-Sheng Zeng; Wei Huang; Bing-Jian Feng; Feng Zhang; Han-Kui Chen; Wei-Hua Jia; Li-Zhen Chen; Qi-Sheng Feng; Ru-Hua Zhang; Xing-Juan Yu; Mei-Zhen Zheng; Yi-Xin Zeng
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Thymosin β4 Is a Determinant of the Transformed Phenotype and Invasiveness of S-Adenosylmethionine Decarboxylase–Transfected Fibroblasts
Pirjo Nummela; Miao Yin; Mari Kielosto; Virna Leaner; Michael J. Birrer; Erkki Hölttä
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Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2
Moammir H. Aziz; Deric L. Wheeler; Bhushan Bhamb; Ajit K. Verma
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TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby
Yusun Jung; Seunghyun Bang; Kyungho Choi; Eunsoon Kim; Youngmi Kim; Jungtae Kim; Juhee Park; Hyunlyoung Koo; Randall T. Moon; Kyuyoung Song; Inchul Lee
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Differential Requirement for DNA Methyltransferase 1 in Maintaining Human Cancer Cell Gene Promoter Hypermethylation
Angela H. Ting; Kam-wing Jair; Kornel E. Schuebel; Stephen B. Baylin
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PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner
Yufang Tang; Charis Eng
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Profiling Genetic Variation along the Androgen Biosynthesis and Metabolism Pathways Implicates Several Single Nucleotide Polymorphisms and Their Combinations as Prostate Cancer Risk Factors
Nina Mononen; Eija H. Seppälä; Priya Duggal; Ville Autio; Tarja Ikonen; Pekka Ellonen; Juha Saharinen; Janna Saarela; Mauno Vihinen; Teuvo L.J. Tammela; Olli Kallioniemi; Joan E. Bailey-Wilson; Johanna Schleutker
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Critical Roles for Polymerase ζ in Cellular Tolerance to Nitric Oxide–Induced DNA Damage
Xiaohua Wu; Katsuya Takenaka; Eiichiro Sonoda; Helfrid Hochegger; Shosuke Kawanishi; Takuo Kawamoto; Shunichi Takeda; Mitsuyoshi Yamazoe
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In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon Receptor
Zhen Yu; Christiane V. Loehr; Kay A. Fischer; Mandy A. Louderback; Sharon K. Krueger; Roderick H. Dashwood; Nancy I. Kerkvliet; Clifford B. Pereira; Jamie E. Jennings-Gee; Stephanie T. Dance; Mark Steven Miller; George S. Bailey; David E. Williams
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Altered Expression and Localization of Creatine Kinase B, Heterogeneous Nuclear Ribonucleoprotein F, and High Mobility Group Box 1 Protein in the Nuclear Matrix Associated with Colon Cancer
Manimalha Balasubramani; Billy W. Day; Robert E. Schoen; Robert H. Getzenberg
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Cell, Tumor, and Stem Cell Biology

Nitric Oxide Is a Factor in the Stabilization of Hypoxia-Inducible Factor-1α in Cancer: Role of Free Radical Formation
Marisol Quintero; Peter A. Brennan; Gareth J. Thomas; Salvador Moncada
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Angiopoietin 2 Induces Glioma Cell Invasion by Stimulating Matrix Metalloprotease 2 Expression through the αvβ1 Integrin and Focal Adhesion Kinase Signaling Pathway
Bo Hu; Michael J. Jarzynka; Ping Guo; Yorihisha Imanishi; David D. Schlaepfer; Shi-Yuan Cheng
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Phospholipase D Prevents Etoposide-Induced Apoptosis by Inhibiting the Expression of Early Growth Response-1 and Phosphatase and Tensin Homologue Deleted on Chromosome 10
Joommo Kim; Young Han Lee; Taeg Kyu Kwon; Jong-Soo Chang; Kwang Chul Chung; Do Sik Min
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The Gene Expression Program of Prostate Fibroblast Senescence Modulates Neoplastic Epithelial Cell Proliferation through Paracrine Mechanisms
Claes Bavik; Ilsa Coleman; James P. Dean; Beatrice Knudsen; Steven Plymate; Peter S. Nelson
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The Possible Role of EWS-Fli1 in Evasion of Senescence in Ewing Family Tumors
Tomoya Matsunobu; Kazuhiro Tanaka; Tomoyuki Nakamura; Fumihiko Nakatani; Riku Sakimura; Masuo Hanada; Xu Li; Takamitsu Okada; Yoshinao Oda; Masazumi Tsuneyoshi; Yukihide Iwamoto
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Overexpression of c-Maf Contributes to T-Cell Lymphoma in Both Mice and Human
Naoki Morito; Keigyou Yoh; Yuki Fujioka; Takako Nakano; Homare Shimohata; Yuko Hashimoto; Akiko Yamada; Atsuko Maeda; Fumihiko Matsuno; Hiroyuki Hata; Atsushi Suzuki; Shigehiko Imagawa; Hiroaki Mitsuya; Hiroyasu Esumi; Akio Koyama; Masayuki Yamamoto; Naoyoshi Mori; Satoru Takahashi
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Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors
James E. Korkola; Jane Houldsworth; Rajendrakumar S.V. Chadalavada; Adam B. Olshen; Debbie Dobrzynski; Victor E. Reuter; George J. Bosl; R.S.K. Chaganti
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Helicobacter Infection Is Required for Inflammation and Colon Cancer in Smad3-Deficient Mice
Lillian Maggio-Price; Piper Treuting; Weiping Zeng; Mark Tsang; Helle Bielefeldt-Ohmann; Brian M. Iritani
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Protein Kinase C-δ and Mitogen-Activated Protein/Extracellular Signal–Regulated Kinase-1 Control GLI Activation in Hedgehog Signaling
Natalia A. Riobo; Gwendolyn M. Haines; Charles P. Emerson, Jr.
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Roles of Myofibroblasts in Prostaglandin E2–Stimulated Intestinal Epithelial Proliferation and Angiogenesis
Jinyi Shao; George G. Sheng; Randy C. Mifflin; Don W. Powell; Hongmiao Sheng
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MSF-A Interacts with Hypoxia-Inducible Factor-1α and Augments Hypoxia-Inducible Factor Transcriptional Activation to Affect Tumorigenicity and Angiogenesis
Sharon Amir; Ruoxiang Wang; Haim Matzkin; Jonathan W. Simons; Nicola J. Mabjeesh
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Differential Gene Expression Analysis Reveals Generation of an Autocrine Loop by a Mutant Epidermal Growth Factor Receptor in Glioma Cells
Deepti B. Ramnarain; Seongmi Park; Diana Y. Lee; Kimmo J. Hatanpaa; Shane O. Scoggin; Hasan Otu; Towia A. Libermann; Jack M. Raisanen; Raheela Ashfaq; Eric T. Wong; Julian Wu; Robert Elliott; Amyn A. Habib
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Angiostatin Is Directly Cytotoxic to Tumor Cells at Low Extracellular pH: A Mechanism Dependent on Cell Surface–Associated ATP Synthase
Sulene L. Chi; Salvatore V. Pizzo
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Increased Expression of Osteopontin Contributes to the Progression of Prostate Cancer
Ani C. Khodavirdi; Zhigang Song; Shangxin Yang; Chen Zhong; Shunyou Wang; Hong Wu; Colin Pritchard; Peter S. Nelson; Pradip Roy-Burman
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Deregulation of the HOXA10 Homeobox Gene in Endometrial Carcinoma: Role in Epithelial-Mesenchymal Transition
Hiroyuki Yoshida; Russell Broaddus; Wenjun Cheng; SuSu Xie; Honami Naora
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Identification of a Putative Tumor Suppressor Gene Rap1GAP in Pancreatic Cancer
Lizhi Zhang; Li Chenwei; Redah Mahmood; Kenneth van Golen; Joel Greenson; Gangyong Li; Nisha J. D'Silva; Xiangquan Li; Charles F. Burant; Craig D. Logsdon; Diane M. Simeone
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The P2X7 Receptor Sustains the Growth of Human Neuroblastoma Cells through a Substance P–Dependent Mechanism
Lizzia Raffaghello; Paola Chiozzi; Simonetta Falzoni; Francesco Di Virgilio; Vito Pistoia
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Effect of Rapamycin on Mouse Chronic Lymphocytic Leukemia and the Development of Nonhematopoietic Malignancies in Eμ-TCL1 Transgenic Mice
Nicola Zanesi; Rami Aqeilan; Alessandra Drusco; Mohamed Kaou; Cinzia Sevignani; Stefan Costinean; Laura Bortesi; Gaspare La Rocca; Pavel Koldovsky; Stefano Volinia; Rita Mancini; George Calin; Charles P. Scott; Yuri Pekarsky; Carlo M. Croce
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Elevated Expression of ISG15 in Tumor Cells Interferes with the Ubiquitin/26S Proteasome Pathway
Shyamal D. Desai; Arthur L. Haas; Laurence M. Wood; Yu-Chen Tsai; Sidney Pestka; Eric H. Rubin; Ahamed Saleem; Alam Nur-E-Kamal; Leroy F. Liu
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Cisplatin Mimics ARF Tumor Suppressor Regulation of RelA (p65) Nuclear Factor-κB Transactivation
Kirsteen J. Campbell; James M. Witty; Sonia Rocha; Neil D. Perkins
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Efficient Inhibition of Intra-Peritoneal Tumor Growth and Dissemination of Human Ovarian Carcinoma Cells in Nude Mice by Anti-L1-Cell Adhesion Molecule Monoclonal Antibody Treatment
Matthias J.E. Arlt; Ilse Novak-Hofer; Daniela Gast; Verena Gschwend; Gerhard Moldenhauer; Jürgen Grünberg; Michael Honer; P. August Schubiger; Peter Altevogt; Achim Krüger
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Restoring E-Cadherin Expression Increases Sensitivity to Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cell Lines
Samir E. Witta; Robert M. Gemmill; Fred R. Hirsch; Christopher D. Coldren; Karla Hedman; Larisa Ravdel; Barbara Helfrich; Rafal Dziadziuszko; Daniel C. Chan; Michio Sugita; Zeng Chan; Anna Baron; Wilbur Franklin; Harry A. Drabkin; Luc Girard; Adi F. Gazdar; John D. Minna; Paul A. Bunn, Jr.
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The Synthetic Compound CC-5079 Is a Potent Inhibitor of Tubulin Polymerization and Tumor Necrosis Factor-α Production with Antitumor Activity
Ling-Hua Zhang; Lei Wu; Heather K. Raymon; Roger S. Chen; Laura Corral; Michael A. Shirley; Rama Krishna Narla; Jim Gamez; George W. Muller; David I. Stirling; J. Blake Bartlett; Peter H. Schafer; Faribourz Payvandi
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Effect of Adenovirus-Mediated Heat Shock Protein Expression and Oncolysis in Combination with Low-Dose Cyclophosphamide Treatment on Antitumor Immune Responses
Nelson C. Di Paolo; Sebastian Tuve; Shaoheng Ni; Karl Erik Hellström; Ingegerd Hellström; André Lieber
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Targeting Cell-Impermeable Prodrug Activation to Tumor Microenvironment Eradicates Multiple Drug-Resistant Neoplasms
Wenyuan Wu; Yunping Luo; Chengzao Sun; Yuan Liu; Paul Kuo; Janos Varga; Rong Xiang; Ralph Reisfeld; Kim D. Janda; Thomas S. Edgington; Cheng Liu
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Synergistic Effects of Gemcitabine and Gefitinib in the Treatment of Head and Neck Carcinoma
Patrick Y. Chun; Felix Y. Feng; Ashley M. Scheurer; Mary A. Davis; Theodore S. Lawrence; Mukesh K. Nyati
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Activity of the Adenoviral E1A Deletion Mutant dl922-947 in Ovarian Cancer: Comparison with E1A Wild-type Viruses, Bioluminescence Monitoring, and Intraperitoneal Delivery in Icodextrin
Michelle Lockley; Mario Fernandez; Yaohe Wang; N. Fiona Li; Susan Conroy; Nicholas Lemoine; Iain McNeish
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Oncogenic BRAF Is Required for Tumor Growth and Maintenance in Melanoma Models
Klaus P. Hoeflich; Daniel C. Gray; Michael T. Eby; Janet Y. Tien; Leo Wong; Janeko Bower; Alvin Gogineni; Jiping Zha; Mary J. Cole; Howard M. Stern; Lesley J. Murray; David P. Davis; Somasekar Seshagiri
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Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
Matthew A. Young; Neil P. Shah; Luke H. Chao; Markus Seeliger; Zdravko V. Milanov; William H. Biggs, III; Daniel K. Treiber; Hitesh K. Patel; Patrick P. Zarrinkar; David J. Lockhart; Charles L. Sawyers; John Kuriyan
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OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models
Andrew J. Garton; Andrew P.A. Crew; Maryland Franklin; Andrew R. Cooke; Graham M. Wynne; Linda Castaldo; Jennifer Kahler; Shannon L. Winski; April Franks; Eric N. Brown; Mark A. Bittner; John F. Keily; Paul Briner; Chris Hidden; Mary C. Srebernak; Carrie Pirrit; Matthew O'Connor; Anna Chan; Bojana Vulevic; Dwight Henninger; Karen Hart; Regina Sennello; An-Hu Li; Tao Zhang; Frank Richardson; David L. Emerson; Arlindo L. Castelhano; Lee D. Arnold; Neil W. Gibson
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Antitumor Activity of Epidermal Growth Factor Receptor–Related Protein Is Mediated by Inactivation of ErbB Receptors and Nuclear Factor-κB in Pancreatic Cancer
Yuxiang Zhang; Sanjeev Banerjee; Zhiwei Wang; Hu Xu; Liyue Zhang; Ramzi Mohammad; Amro Aboukameel; Nazmi V. Adsay; Mingxin Che; James L. Abbruzzese; Adhip P.N. Majumdar; Fazlul H. Sarkar
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The Penetration of Anticancer Drugs through Tumor Tissue as a Function of Cellular Adhesion and Packing Density of Tumor Cells
Rama Grantab; Shankar Sivananthan; Ian F. Tannock
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Farnesyl and Geranylgeranyl Transferase Inhibitors Induce G1 Arrest by Targeting the Proteasome
Ekem T. Efuet; Khandan Keyomarsi
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Radiation-Induced Changes in Gene Expression Involve Recruitment of Existing Messenger RNAs to and away from Polysomes
Xing Lü; Lorena de la Peña; Christopher Barker; Kevin Camphausen; Philip J. Tofilon
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RNA Interference–Mediated Depletion of Phosphoinositide 3-Kinase Activates Forkhead Box Class O Transcription Factors and Induces Cell Cycle Arrest and Apoptosis in Breast Carcinoma Cells
Shannon Reagan-Shaw; Nihal Ahmad
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Rapamycin Disrupts Cyclin/Cyclin-Dependent Kinase/p21/Proliferating Cell Nuclear Antigen Complexes and Cyclin D1 Reverses Rapamycin Action by Stabilizing These Complexes
Mary Law; Elizabeth Forrester; Anna Chytil; Patrick Corsino; Gail Green; Bradley Davis; Thomas Rowe; Brian Law
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Intracellular Signaling Pathways Involved in the Cell Growth Inhibition of Glioma Cells by Melatonin
Vanesa Martín; Federico Herrera; Pilar Carrera-Gonzalez; Guillermo García-Santos; Isaac Antolín; Jezabel Rodriguez-Blanco; Carmen Rodriguez
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17-Allylamino-17-Demethoxygeldanamycin Synergistically Potentiates Tumor Necrosis Factor–Induced Lung Cancer Cell Death by Blocking the Nuclear Factor-κB Pathway
Xia Wang; Wei Ju; Jordan Renouard; James Aden; Steven A. Belinsky; Yong Lin
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Immunology

Selective Targeting of Antitumor Immune Responses with Engineered Live-Attenuated Listeria monocytogenes
Kiyoshi Yoshimura; Ajay Jain; Heather E. Allen; Lindsay S. Laird; Christina Y. Chia; Sowmya Ravi; Dirk G. Brockstedt; Martin A. Giedlin; Keith S. Bahjat; Meredith L. Leong; Jill E. Slansky; David N. Cook; Thomas W. Dubensky; Drew M. Pardoll; Richard D. Schulick
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De novo Induction of a Cancer/Testis Antigen by 5-Aza-2′-Deoxycytidine Augments Adoptive Immunotherapy in a Murine Tumor Model
Z. Sheng Guo; Julie A. Hong; Kari R. Irvine; G. Aaron Chen; Paul J. Spiess; Yang Liu; Gang Zeng; John R. Wunderlich; Dao M. Nguyen; Nicholas P. Restifo; David S. Schrump
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Prostaglandin E2 Impairs CD4+ T Cell Activation by Inhibition of lck: Implications in Hodgkin's Lymphoma
Jens M. Chemnitz; Julia Driesen; Sabine Classen; James L. Riley; Svenja Debey; Marc Beyer; Alexey Popov; Thomas Zander; Joachim L. Schultze
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Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host
Bo Huang; Ping-Ying Pan; Qingsheng Li; Alice I. Sato; David E. Levy; Jonathan Bromberg; Celia M. Divino; Shu-Hsia Chen
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The In vivo Expansion Rate of Properly Stimulated Transferred CD8+ T Cells Exceeds That of an Aggressively Growing Mouse Tumor
Leroy N. Hwang; Zhiya Yu; Douglas C. Palmer; Nicholas P. Restifo
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Radiofrequency Thermal Ablation of Hepatocellular Carcinoma Liver Nodules Can Activate and Enhance Tumor-Specific T-Cell Responses
Alessandro Zerbini; Massimo Pilli; Amalia Penna; Guido Pelosi; Claudia Schianchi; Atim Molinari; Simona Schivazappa; Carlo Zibera; Francesco F. Fagnoni; Carlo Ferrari; Gabriele Missale
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Tumor Cells Transduced with the MHC Class II Transactivator and CD80 Activate Tumor-Specific CD4+ T Cells Whether or Not They Are Silenced for Invariant Chain
James A. Thompson; Samudra K. Dissanayake; Bruce R. Ksander; Keith L. Knutson; Mary L. Disis; Suzanne Ostrand-Rosenberg
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Efficient Induction of Tumor Antigen–Specific CD8+ Memory T Cells by Recombinant Lentivectors
Laurence Chapatte; Sara Colombetti; Jean-Charles Cerottini; Frédéric Lévy
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Chaperoning Function of Stress Protein grp170, a Member of the hsp70 Superfamily, Is Responsible for its Immunoadjuvant Activity
Jun-Eui Park; John Facciponte; Xing Chen; Ian MacDonald; Elizabeth A. Repasky; Masoud H. Manjili; Xiang-Yang Wang; John R. Subjeck
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Vaccine with β-Defensin 2–Transduced Leukemic Cells Activates Innate and Adaptive Immunity to Elicit Potent Antileukemia Responses
Xiao-Tong Ma; Bin Xu; Li-Li An; Cheng-Ya Dong; Yong-Min Lin; Yang Shi; Ke-Fu Wu
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Endocrinology

Polymorphisms in RET and Its Coreceptors and Ligands as Genetic Modifiers of Multiple Endocrine Neoplasia Type 2A
Fabienne Lesueur; Arancha Cebrian; Mercedes Robledo; Patricia Niccoli-Sire; Karl-Axel Svensson; Stephane Pinson; Jean Leyland; Joanne Whittaker; Paul D. Pharoah; Bruce A.J. Ponder
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Clinical Research

Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays
Madhumita Chatterjee; Saroj Mohapatra; Alexei Ionan; Gagandeep Bawa; Rouba Ali-Fehmi; Xiaoju Wang; James Nowak; Bin Ye; Fatimah A. Nahhas; Karen Lu; Steven S. Witkin; David Fishman; Adnan Munkarah; Robert Morris; Nancy K. Levin; Natalie N. Shirley; Gerard Tromp; Judith Abrams; Sorin Draghici; Michael A. Tainsky
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Expression of a Fibroblast Growth Factor–Binding Protein during the Development of Adenocarcinoma of the Pancreas and Colon
Elena Tassi; Ralf T. Henke; Emma T. Bowden; Matthew R. Swift; David P. Kodack; Angera H. Kuo; Anirban Maitra; Anton Wellstein
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Induction of Metastasis by S100P in a Rat Mammary Model and Its Association with Poor Survival of Breast Cancer Patients
Guozheng Wang; Angela Platt-Higgins; Joe Carroll; Suzete de Silva Rudland; John Winstanley; Roger Barraclough; Philip S. Rudland
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DNA Methylation Alterations in the Pancreatic Juice of Patients with Suspected Pancreatic Disease
Hiroyuki Matsubayashi; Marcia Canto; Norihiro Sato; Alison Klein; Tadayoshi Abe; Keishi Yamashita; Charles J. Yeo; Anthony Kalloo; Ralph Hruban; Michael Goggins
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Epidemiology and Prevention

Age-Related Changes of the Cervix Influence Human Papillomavirus Type Distribution
Philip E. Castle; Jose Jeronimo; Mark Schiffman; Rolando Herrero; Ana C. Rodríguez; M. Concepción Bratti; Allan Hildesheim; Sholom Wacholder; L. Rodney Long; Leif Neve; Ruth Pfeiffer; Robert D. Burk
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Tagging Single-Nucleotide Polymorphisms in Antioxidant Defense Enzymes and Susceptibility to Breast Cancer
Arancha Cebrian; Paul D. Pharoah; Shahana Ahmed; Paula L. Smith; Craig Luccarini; Robert Luben; Karen Redman; Hannah Munday; Douglas F. Easton; Alison M. Dunning; Bruce A.J. Ponder
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Chemoprevention of Human Prostate Cancer by Oral Administration of Green Tea Catechins in Volunteers with High-Grade Prostate Intraepithelial Neoplasia: A Preliminary Report from a One-Year Proof-of-Principle Study
Saverio Bettuzzi; Maurizio Brausi; Federica Rizzi; Giovanni Castagnetti; Giancarlo Peracchia; Arnaldo Corti
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Dietary Soy Isoflavones Inhibit Estrogen Effects in the Postmenopausal Breast
Charles E. Wood; Thomas C. Register; Adrian A. Franke; Mary S. Anthony; J. Mark Cline
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Correction

Promotion of Invasion and Metastatic Potential by Bcl-2
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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