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Issues

Volume 65, Issue 8
15 April 2005
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Reviews

Experimental Design and Analysis of Antibody Microarrays: Applying Methods from cDNA Arrays
Jeanette E. Eckel-Passow; Antje Hoering; Terry M. Therneau; Irene Ghobrial
View articletitled, Experimental Design and Analysis of Antibody Microarrays: Applying Methods from cDNA Arrays
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Therapeutic Targeting of the Hedgehog-GLI Pathway in Prostate Cancer
Pilar Sanchez; Virginie Clement; Ariel Ruiz i Altaba
View articletitled, Therapeutic Targeting of the Hedgehog-GLI Pathway in Prostate Cancer
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Lysosomes as Targets for Cancer Therapy
Nicole Fehrenbacher; Marja Jäättelä
View articletitled, Lysosomes as Targets for Cancer Therapy
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Editorial Note

Genetics and Latinos: Proceedings of a National Summit
Amelie G. Ramirez, Dr.P.H.; Jorge Gomez, M.D., Ph.D.
View articletitled, Genetics and Latinos: Proceedings of a National Summit
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Perspectives in Cancer Research

The Hydra Phenomenon of Cancer: Why Tumors Recur Locally after Microscopically Complete Resection
Michael Höckel; Nadja Dornhöfer
View articletitled, The Hydra Phenomenon of Cancer: Why Tumors Recur Locally after Microscopically Complete Resection
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Priority Reports

Epidermal Growth Factor Receptor Dynamics Influences Response to Epidermal Growth Factor Receptor Targeted Agents
Antonio Jimeno; Belen Rubio-Viqueira; Maria L. Amador; Darin Oppenheimer; Nadia Bouraoud; Peter Kulesza; Valeria Sebastiani; Anirban Maitra; Manuel Hidalgo
View articletitled, Epidermal Growth Factor Receptor Dynamics Influences Response to Epidermal Growth Factor Receptor Targeted Agents
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Linking Transcriptional Elongation and Messenger RNA Export to Metastatic Breast Cancers
Shanchun Guo; Mohamed-Ali Hakimi; David Baillat; Xiaowei Chen; Michele J. Farber; Andres J.P. Klein-Szanto; Neil S. Cooch; Andrew K. Godwin; Ramin Shiekhattar
View articletitled, Linking Transcriptional Elongation and Messenger RNA Export to Metastatic Breast Cancers
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Activation of the Fas-FasL Signaling Pathway by MDA-7/IL-24 Kills Human Ovarian Cancer Cells
Began Gopalan; Anya Litvak; Sikha Sharma; Abner M. Mhashilkar; Sunil Chada; Rajagopal Ramesh
View articletitled, Activation of the Fas-FasL Signaling Pathway by MDA-7/IL-24 Kills Human Ovarian Cancer Cells
Supplementary data
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Stem and Progenitor-Like Cells Contribute to the Aggressive Behavior of Human Epithelial Ovarian Cancer
Sharmila A. Bapat; Avinash M. Mali; Chaitanyananda B. Koppikar; Nawneet K. Kurrey
View articletitled, Stem and Progenitor-Like Cells Contribute to the Aggressive Behavior of Human Epithelial Ovarian Cancer
Supplementary data
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Metabolic Characterization of Human Prostate Cancer with Tissue Magnetic Resonance Spectroscopy
Leo L. Cheng; Melissa A. Burns; Jennifer L. Taylor; Wenlei He; Elkan F. Halpern; W. Scott McDougal; Chin-Lee Wu
View articletitled, Metabolic Characterization of Human Prostate Cancer with Tissue Magnetic Resonance Spectroscopy
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Spontaneous Human Adult Stem Cell Transformation
Daniel Rubio; Javier Garcia-Castro; María C. Martín; Ricardo de la Fuente; Juan C. Cigudosa; Alison C. Lloyd; Antonio Bernad
View articletitled, Spontaneous Human Adult Stem Cell Transformation
Supplementary data
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Ceratamines, Structurally Simple Microtubule-Stabilizing Antimitotic Agents with Unusual Cellular Effects
Geoffrey Karjala; Queenie Chan; Emiliano Manzo; Raymond J. Andersen; Michel Roberge
View articletitled, Ceratamines, Structurally Simple Microtubule-Stabilizing Antimitotic Agents with Unusual Cellular Effects
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Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion
Arnold H. Zea; Paulo C. Rodriguez; Michael B. Atkins; Claudia Hernandez; Sabina Signoretti; Jovanny Zabaleta; David McDermott; David Quiceno; Amanda Youmans; Anne O'Neill; James Mier; Augusto C. Ochoa
View articletitled, Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion
Supplementary data
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SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study
Alfonso Cristaudo; Rudy Foddis; Agnese Vivaldi; Rodolfo Buselli; Vittorio Gattini; Giovanni Guglielmi; Francesca Cosentino; Franco Ottenga; Eugenio Ciancia; Roberta Libener; Rosangela Filiberti; Monica Neri; PierGiacomo Betta; Mauro Tognon; Luciano Mutti; Riccardo Puntoni
View articletitled, SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study
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Loss of Heterozygosity in Childhood Acute Lymphoblastic Leukemia Detected by Genome-Wide Microarray Single Nucleotide Polymorphism Analysis
Julie A.E. Irving; Lisa Bloodworth; Nick P. Bown; Marian C. Case; Linda A. Hogarth; Andrew G. Hall
View articletitled, Loss of Heterozygosity in Childhood Acute Lymphoblastic Leukemia Detected by Genome-Wide Microarray Single Nucleotide Polymorphism Analysis
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Serum Soluble Epidermal Growth Factor Receptor Concentrations Decrease in Postmenopausal Metastatic Breast Cancer Patients Treated with Letrozole
Jacqueline M. Lafky; Andre T. Baron; Elsa M. Cora; David W. Hillman; Vera J. Suman; Edith A. Perez; James N. Ingle; Nita J. Maihle
View articletitled, Serum Soluble Epidermal Growth Factor Receptor Concentrations Decrease in Postmenopausal Metastatic Breast Cancer Patients Treated with Letrozole
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Molecular Biology, Pathobiology, and Genetics

Gene Expression Profiling Allows Distinction between Primary and Metastatic Squamous Cell Carcinomas in the Lung
Simon G. Talbot; Cherry Estilo; Ellie Maghami; Inderpal S. Sarkaria; Duy Khanh Pham; Pornchai O-charoenrat; Nicholas D. Socci; Ivan Ngai; Diane Carlson; Ronald Ghossein; Agnes Viale; Bernard J. Park; Valerie W. Rusch; Bhuvanesh Singh
View articletitled, Gene Expression Profiling Allows Distinction between Primary and Metastatic Squamous Cell Carcinomas in the Lung
Supplementary data
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Expression of the Brn-3b Transcription Factor Correlates with Expression of HSP-27 in Breast Cancer Biopsies and Is Required for Maximal Activation of the HSP-27 Promoter
Sonia A. Lee; Daniel Ndisang; Chandrakant Patel; Jonathan H. Dennis; David J. Faulkes; Corrado D'Arrigo; Laila Samady; Saleha Farooqui-Kabir; Richard J. Heads; David S. Latchman; Vishwanie S. Budhram-Mahadeo
View articletitled, Expression of the Brn-3b Transcription Factor Correlates with Expression of HSP-27 in Breast Cancer Biopsies and Is Required for Maximal Activation of the HSP-27 Promoter
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Evidence for the Presence of Disease-Perturbed Networks in Prostate Cancer Cells by Genomic and Proteomic Analyses: A Systems Approach to Disease
Biaoyang Lin; James T. White; Wei Lu; Tao Xie; Angelita G. Utleg; Xiaowei Yan; Eugene C. Yi; Paul Shannon; Irina Khrebtukova; Paul H. Lange; David R. Goodlett; Daixing Zhou; Thomas J. Vasicek; Leroy Hood
View articletitled, Evidence for the Presence of Disease-Perturbed Networks in Prostate Cancer Cells by Genomic and Proteomic Analyses: A Systems Approach to Disease
Supplementary data
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Overexpressed P-Cadherin/CDH3 Promotes Motility of Pancreatic Cancer Cells by Interacting with p120ctn and Activating Rho-Family GTPases
Keisuke Taniuchi; Hidewaki Nakagawa; Masayo Hosokawa; Toru Nakamura; Hidetoshi Eguchi; Hiroaki Ohigashi; Osamu Ishikawa; Toyomasa Katagiri; Yusuke Nakamura
View articletitled, Overexpressed P-Cadherin/CDH3 Promotes Motility of Pancreatic Cancer Cells by Interacting with p120ctn and Activating Rho-Family GTPases
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Influence of Mast Cells on Structural and Functional Manifestations of Radiation-Induced Heart Disease
Marjan Boerma; Junru Wang; Jan Wondergem; Jacob Joseph; Xiaohua Qiu; Richard H. Kennedy; Martin Hauer-Jensen
View articletitled, Influence of Mast Cells on Structural and Functional Manifestations of Radiation-Induced Heart Disease
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The Serine/Threonine Protein Kinase, p90 Ribosomal S6 Kinase, Is an Important Regulator of Prostate Cancer Cell Proliferation
D.E. Clark; T.M. Errington; J.A. Smith; H.F. Frierson, Jr.; M.J. Weber; D.A. Lannigan
View articletitled, The Serine/Threonine Protein Kinase, p90 Ribosomal S6 Kinase, Is an Important Regulator of Prostate Cancer Cell Proliferation
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Cell and Tumor Biology

RRP22 Is a Farnesylated, Nucleolar, Ras-Related Protein with Tumor Suppressor Potential
Candice Elam; Luke Hesson; Michele D. Vos; Kristin Eckfeld; Chad A. Ellis; Aaron Bell; Dietmar Krex; Michael J. Birrer; Farida Latif; Geoffrey J. Clark
View articletitled, RRP22 Is a Farnesylated, Nucleolar, Ras-Related Protein with Tumor Suppressor Potential
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Tumorigenic Heterogeneity in Cancer Stem Cells Evolved from Long-term Cultures of Telomerase-Immortalized Human Mesenchymal Stem Cells
Jorge S. Burns; Basem M. Abdallah; Per Guldberg; Jørgen Rygaard; Henrik D. Schrøder; Moustapha Kassem
View articletitled, Tumorigenic Heterogeneity in Cancer Stem Cells Evolved from Long-term Cultures of Telomerase-Immortalized Human Mesenchymal Stem Cells
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Inhibition of a New Differentiation Pathway in Neuroblastoma by Copy Number Defects of N-myc, Cdc42, and nm23 Genes
Linda J. Valentijn; Arjen Koppen; Ronald van Asperen; Heather A. Root; Franciska Haneveld; Rogier Versteeg
View articletitled, Inhibition of a New Differentiation Pathway in Neuroblastoma by Copy Number Defects of <em>N-myc</em>, <em>Cdc42</em>, and <em>nm23</em> Genes
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Progression of Barrett's Metaplasia to Adenocarcinoma Is Associated with the Suppression of the Transcriptional Programs of Epidermal Differentiation
Erik T. Kimchi; Mitchell C. Posner; James O. Park; Thomas E. Darga; Masha Kocherginsky; Theodore Karrison; John Hart; Kerrington D. Smith; James J. Mezhir; Ralph R. Weichselbaum; Nikolai N. Khodarev
View articletitled, Progression of Barrett's Metaplasia to Adenocarcinoma Is Associated with the Suppression of the Transcriptional Programs of Epidermal Differentiation
Supplementary data
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Immortal DNA Strand Cosegregation Requires p53/IMPDH–Dependent Asymmetric Self-renewal Associated with Adult Stem Cells
Lakshmi Rambhatla; Sumati Ram-Mohan; Jennifer J. Cheng; James L. Sherley
View articletitled, Immortal DNA Strand Cosegregation Requires p53/IMPDH–Dependent Asymmetric Self-renewal Associated with Adult Stem Cells
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Down-regulation of Mitochondrial F1F0-ATP Synthase in Human Colon Cancer Cells with Induced 5-Fluorouracil Resistance
Young-Kyoung Shin; Byong Chul Yoo; Hee Jin Chang; Eunkyung Jeon; Sung-Hye Hong; Mi-Sun Jung; Soo-Jeong Lim; Jae-Gahb Park
View articletitled, Down-regulation of Mitochondrial F<sub>1</sub>F<sub>0</sub>-ATP Synthase in Human Colon Cancer Cells with Induced 5-Fluorouracil Resistance
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Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment
Ioanna Papandreou; Chaya Krishna; Fiona Kaper; Deli Cai; Amato J. Giaccia; Nicholas C. Denko
View articletitled, Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment
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Pak1 Phosphorylation of Snail, a Master Regulator of Epithelial-to-Mesenchyme Transition, Modulates Snail's Subcellular Localization and Functions
Zhibo Yang; Suresh Rayala; Diep Nguyen; Ratna K. Vadlamudi; Shiuan Chen; Rakesh Kumar
View articletitled, Pak1 Phosphorylation of Snail, a Master Regulator of Epithelial-to-Mesenchyme Transition, Modulates Snail's Subcellular Localization and Functions
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Fetal Stromal–Dependent Paracrine and Intracrine Vascular Endothelial Growth Factor-A/Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Proliferation and Motility of Human Primary Myeloma Cells
Loïc Vincent; David K. Jin; Matthias A. Karajannis; Koji Shido; Andrea T. Hooper; William K. Rashbaum; Bronislaw Pytowski; Yan Wu; Daniel J. Hicklin; Zhenping Zhu; Peter Bohlen; Ruben Niesvizky; Shahin Rafii
View articletitled, Fetal Stromal–Dependent Paracrine and Intracrine Vascular Endothelial Growth Factor-A/Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Proliferation and Motility of Human Primary Myeloma Cells
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Extracellular Matrix Metalloproteinase Inducer Stimulates Tumor Angiogenesis by Elevating Vascular Endothelial Cell Growth Factor and Matrix Metalloproteinases
Yi Tang; Marian T. Nakada; Prabakaran Kesavan; Francis McCabe; Hillary Millar; Patricia Rafferty; Peter Bugelski; Li Yan
View articletitled, Extracellular Matrix Metalloproteinase Inducer Stimulates Tumor Angiogenesis by Elevating Vascular Endothelial Cell Growth Factor and Matrix Metalloproteinases
Supplementary data
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The Contribution of Bone Marrow–Derived Cells to the Tumor Vasculature in Neuroblastoma Is Matrix Metalloproteinase-9 Dependent
Sonata Jodele; Christophe F. Chantrain; Laurence Blavier; Carolyn Lutzko; Gay M. Crooks; Hiroyuki Shimada; Lisa M. Coussens; Yves A. DeClerck
View articletitled, The Contribution of Bone Marrow–Derived Cells to the Tumor Vasculature in Neuroblastoma Is Matrix Metalloproteinase-9 Dependent
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Nuclear Factor-κB–Dependent Mechanisms in Breast Cancer Cells Regulate Tumor Burden and Osteolysis in Bone
Andrew H. Gordon; Regis J. O'Keefe; Edward M. Schwarz; Randy N. Rosier; J. Edward Puzas
View articletitled, Nuclear Factor-κB–Dependent Mechanisms in Breast Cancer Cells Regulate Tumor Burden and Osteolysis in Bone
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High Nuclear S100A6 (Calcyclin) Is Significantly Associated with Poor Survival in Pancreatic Cancer Patients
Dale Vimalachandran; William Greenhalf; Christopher Thompson; Jutta Lüttges; Wendy Prime; Fiona Campbell; Andrew Dodson; Richard Watson; Tatjana Crnogorac-Jurcevic; Nicholas Lemoine; John Neoptolemos; Eithne Costello
View articletitled, High Nuclear S100A6 (Calcyclin) Is Significantly Associated with Poor Survival in Pancreatic Cancer Patients
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Inhibition of Mammalian Target of Rapamycin Reverses Alveolar Epithelial Neoplasia Induced by Oncogenic K-ras
Marie Wislez; M. Loreto Spencer; Julie G. Izzo; Denise M. Juroske; Kamna Balhara; Dianna D. Cody; Roger E. Price; Walter N. Hittelman; Ignacio I. Wistuba; Jonathan M. Kurie
View articletitled, Inhibition of Mammalian Target of Rapamycin Reverses Alveolar Epithelial Neoplasia Induced by Oncogenic <em>K-ras</em>
Supplementary data
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Mitochondrial Damage Mediates Genotoxicity of Arsenic in Mammalian Cells
Su-Xian Liu; Mercy M. Davidson; Xiuwei Tang; Winsome F. Walker; Mohammad Athar; Vladimir Ivanov; Tom K. Hei
View articletitled, Mitochondrial Damage Mediates Genotoxicity of Arsenic in Mammalian Cells
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Suppression of Ovarian Cancer Cell Tumorigenicity and Evasion of Cisplatin Resistance Using a Truncated Epidermal Growth Factor Receptor in a Rat Model
John K. Chan; Huyen Pham; Xue Juan You; Noelle G. Cloven; Robert A. Burger; G. Scott Rose; Kristi Van Nostrand; Murray Korc; Philip J. DiSaia; Hung Fan
View articletitled, Suppression of Ovarian Cancer Cell Tumorigenicity and Evasion of Cisplatin Resistance Using a Truncated Epidermal Growth Factor Receptor in a Rat Model
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Mouse p10, an Alternative Spliced Form of p15INK4b, Inhibits Cell Cycle Progression and Malignant Transformation
Ignacio Pérez de Castro; Marta Benet; María Jiménez; Saba Alzabin; Marcos Malumbres; Angel Pellicer
View articletitled, Mouse p10, an Alternative Spliced Form of p15<sup><em>INK4b</em></sup>, Inhibits Cell Cycle Progression and Malignant Transformation
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A Hypoxia-Independent Hypoxia-Inducible Factor-1 Activation Pathway Induced by Phosphatidylinositol-3 Kinase/Akt in HER2 Overexpressing Cells
Yan M. Li; Binhua P. Zhou; Jiong Deng; Yong Pan; Nissim Hay; Mien-Chie Hung
View articletitled, A Hypoxia-Independent Hypoxia-Inducible Factor-1 Activation Pathway Induced by Phosphatidylinositol-3 Kinase/Akt in HER2 Overexpressing Cells
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BCR-ABL Induces the Expression of Skp2 through the PI3K Pathway to Promote p27Kip1 Degradation and Proliferation of Chronic Myelogenous Leukemia Cells
Enrique J. Andreu; Elisa Lledó; Enric Poch; Carmen Ivorra; M. Pilar Albero; José Angel Martínez-Climent; Cristina Montiel-Duarte; José Rifón; Javier Pérez-Calvo; Cristina Arbona; Felipe Prósper; Ignacio Pérez-Roger
View articletitled, BCR-ABL Induces the Expression of Skp2 through the PI3K Pathway to Promote p27<sup>Kip1</sup> Degradation and Proliferation of Chronic Myelogenous Leukemia Cells
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Cortactin Overexpression Inhibits Ligand-Induced Down-regulation of the Epidermal Growth Factor Receptor
Paul Timpson; Danielle K. Lynch; Daniel Schramek; Francesca Walker; Roger J. Daly
View articletitled, Cortactin Overexpression Inhibits Ligand-Induced Down-regulation of the Epidermal Growth Factor Receptor
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Role for the Nuclear Factor κB Pathway in Transforming Growth Factor-β1 Production in Idiopathic Myelofibrosis: Possible Relationship with FK506 Binding Protein 51 Overexpression
Emiko Komura; Carole Tonetti; Virginie Penard-Lacronique; Hédia Chagraoui; Catherine Lacout; Jean Pierre LeCouédic; Philippe Rameau; Najet Debili; William Vainchenker; Stéphane Giraudier
View articletitled, Role for the Nuclear Factor κB Pathway in Transforming Growth Factor-β1 Production in Idiopathic Myelofibrosis: Possible Relationship with FK506 Binding Protein 51 Overexpression
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Defective p38 Mitogen-Activated Protein Kinase Signaling Impairs Chemotaxic but not Proliferative Responses to Stromal-Derived Factor-1α in Acute Lymphoblastic Leukemia
Linda J. Bendall; Rana Baraz; Julius Juarez; Wei Shen; Kenneth F. Bradstock
View articletitled, Defective p38 Mitogen-Activated Protein Kinase Signaling Impairs Chemotaxic but not Proliferative Responses to Stromal-Derived Factor-1α in Acute Lymphoblastic Leukemia
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Differential Gene Up-Regulation by Hypoxia-Inducible Factor-1α and Hypoxia-Inducible Factor-2α in HEK293T Cells
Victoria Wang; David A. Davis; Muzammel Haque; L. Eric Huang; Robert Yarchoan
View articletitled, Differential Gene Up-Regulation by Hypoxia-Inducible Factor-1α and Hypoxia-Inducible Factor-2α in HEK293T Cells
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas
Akira Nakamizo; Frank Marini; Toshiyuki Amano; Asadullah Khan; Matus Studeny; Joy Gumin; Julianne Chen; Stephen Hentschel; Giacomo Vecil; Jennifer Dembinski; Michael Andreeff; Frederick F. Lang
View articletitled, Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas
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Mitochondrial Targeting of Human O6-Methylguanine DNA Methyltransferase Protects against Cell Killing by Chemotherapeutic Alkylating Agents
Shanbao Cai; Yi Xu; Ryan J. Cooper; Michael J. Ferkowicz; Jennifer R. Hartwell; Karen E. Pollok; Mark R. Kelley
View articletitled, Mitochondrial Targeting of Human <em>O</em><sup>6</sup>-Methylguanine DNA Methyltransferase Protects against Cell Killing by Chemotherapeutic Alkylating Agents
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Mechanisms of Enhanced Radiation Response following Epidermal Growth Factor Receptor Signaling Inhibition by Erlotinib (Tarceva)
Prakash Chinnaiyan; Shyhmin Huang; Geetha Vallabhaneni; Eric Armstrong; Sooryanarayana Varambally; Scott A. Tomlins; Arul M. Chinnaiyan; Paul M. Harari
View articletitled, Mechanisms of Enhanced Radiation Response following Epidermal Growth Factor Receptor Signaling Inhibition by Erlotinib (Tarceva)
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Synergistic Augmentation of Rapamycin-Induced Autophagy in Malignant Glioma Cells by Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibitors
Hayato Takeuchi; Yasuko Kondo; Keishi Fujiwara; Takao Kanzawa; Hiroshi Aoki; Gordon B. Mills; Seiji Kondo
View articletitled, Synergistic Augmentation of Rapamycin-Induced Autophagy in Malignant Glioma Cells by Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibitors
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Construction of a Minimal HIV-1 Variant that Selectively Replicates in Leukemic Derived T-Cell Lines: Towards a New Virotherapy Approach
Rienk E. Jeeninga; Barbara Jan; Birgit van der Linden; Henk van den Berg; Ben Berkhout
View articletitled, Construction of a Minimal HIV-1 Variant that Selectively Replicates in Leukemic Derived T-Cell Lines: Towards a New Virotherapy Approach
Supplementary data
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Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition
Mounia Beloueche-Babari; L. Elizabeth Jackson; Nada M.S. Al-Saffar; Paul Workman; Martin O. Leach; Sabrina M. Ronen
View articletitled, Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition
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Phenoxodiol, a Novel Isoflavone, Induces G1 Arrest by Specific Loss in Cyclin-Dependent Kinase 2 Activity by p53-Independent Induction of p21WAF1/CIP1
Martin F. Aguero; Maria M. Facchinetti; Zhanna Sheleg; Adrian M. Senderowicz
View articletitled, Phenoxodiol, a Novel Isoflavone, Induces G<sub>1</sub> Arrest by Specific Loss in Cyclin-Dependent Kinase 2 Activity by p53-Independent Induction of p21<sup>WAF1/CIP1</sup>
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C-C Chemokine Receptor 5 on Stromal Cells Promotes Pulmonary Metastasis
Hendrik W. van Deventer; William O'Connor, Jr.; W. June Brickey; Robert M. Aris; Jenny P.Y. Ting; Jonathan S. Serody
View articletitled, C-C Chemokine Receptor 5 on Stromal Cells Promotes Pulmonary Metastasis
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Target Cell–Restricted Apoptosis Induction of Acute Leukemic T Cells by a Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Protein with Specificity for Human CD7
Edwin Bremer; Douwe F. Samplonius; Matthias Peipp; Linda van Genne; Bart-Jan Kroesen; Georg H. Fey; Martin Gramatzki; Lou F.M.H. de Leij; Wijnand Helfrich
View articletitled, Target Cell–Restricted Apoptosis Induction of Acute Leukemic T Cells by a Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Protein with Specificity for Human CD7
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Anticancer Activity of the Antibiotic Clioquinol
Wei-Qun Ding; Bolin Liu; Joshua L. Vaught; Hanako Yamauchi; Stuart E. Lind
View articletitled, Anticancer Activity of the Antibiotic Clioquinol
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Dietary Genistein Reduces Metastasis in a Postsurgical Orthotopic Breast Cancer Model
Sharon A. Vantyghem; Sylvia M. Wilson; Carl O. Postenka; Waleed Al-Katib; Alan B. Tuck; Ann F. Chambers
View articletitled, Dietary Genistein Reduces Metastasis in a Postsurgical Orthotopic Breast Cancer Model
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Inhibition of HER-2/neu Kinase Impairs Androgen Receptor Recruitment to the Androgen Responsive Enhancer
Yuanbo Liu; Samarpan Majumder; Wesley McCall; Carolyn I. Sartor; James L. Mohler; Christopher W. Gregory; H. Shelton Earp; Young E. Whang
View articletitled, Inhibition of HER-2/neu Kinase Impairs Androgen Receptor Recruitment to the Androgen Responsive Enhancer
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Immunology

DNA Vaccine Expressing the Mimotope of GD2 Ganglioside Induces Protective GD2 Cross-reactive Antibody Responses
Elizabeth Bolesta; Aleksandra Kowalczyk; Andrzej Wierzbicki; Piotr Rotkiewicz; Barbara Bambach; Chun-Yen Tsao; Irena Horwacik; Andrzej Kolinski; Hanna Rokita; Martin Brecher; Xinhui Wang; Soldano Ferrone; Danuta Kozbor
View articletitled, DNA Vaccine Expressing the Mimotope of GD2 Ganglioside Induces Protective GD2 Cross-reactive Antibody Responses
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A DNA Vaccine Targeting Fos-Related Antigen 1 Enhanced by IL-18 Induces Long-lived T-Cell Memory against Tumor Recurrence
Yunping Luo; He Zhou; Masato Mizutani; Noriko Mizutani; Cheng Liu; Rong Xiang; Ralph A. Reisfeld
View articletitled, A DNA Vaccine Targeting Fos-Related Antigen 1 Enhanced by IL-18 Induces Long-lived T-Cell Memory against Tumor Recurrence
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Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles
Roberta Mortarini; Alessia Scarito; Daisuke Nonaka; Marina Zanon; Ilaria Bersani; Elisabetta Montaldi; Elisabetta Pennacchioli; Roberto Patuzzo; Mario Santinami; Andrea Anichini
View articletitled, Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles
Supplementary data
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Redirecting In vivo Elicited Tumor Infiltrating Macrophages and Dendritic Cells towards Tumor Rejection
Cristiana Guiducci; Alain P. Vicari; Sabina Sangaletti; Giorgio Trinchieri; Mario P. Colombo
View articletitled, Redirecting <em>In vivo</em> Elicited Tumor Infiltrating Macrophages and Dendritic Cells towards Tumor Rejection
Supplementary data
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IFN Unresponsiveness in LNCaP Cells Due to the Lack of JAK1 Gene Expression
Gavin P. Dunn; Kathleen C.F. Sheehan; Lloyd J. Old; Robert D. Schreiber
View articletitled, IFN Unresponsiveness in LNCaP Cells Due to the Lack of <em>JAK1</em> Gene Expression
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Epidemiology and Prevention

Combined Genetic Assessment of Transforming Growth Factor-β Signaling Pathway Variants May Predict Breast Cancer Risk
Virginia G. Kaklamani; Lisa Baddi; Junjian Liu; Diana Rosman; Sharbani Phukan; Ciarán Bradley; Chris Hegarty; Bree McDaniel; Alfred Rademaker; Carole Oddoux; Harry Ostrer; Loren S. Michel; Helen Huang; Yu Chen; Habibul Ahsan; Kenneth Offit; Boris Pasche
View articletitled, Combined Genetic Assessment of Transforming Growth Factor-β Signaling Pathway Variants May Predict Breast Cancer Risk
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The Retinoid X Receptor-Selective Retinoid, LGD1069, Down-regulates Cyclooxygenase-2 Expression in Human Breast Cells through Transcription Factor Crosstalk: Implications for Molecular-Based Chemoprevention
Gu Kong; Hee-Tae Kim; Kendall Wu; David DeNardo; Susan G. Hilsenbeck; Xiao-Chun Xu; William W. Lamph; Reid Bissonnette; Andrew J. Dannenberg; Powel H. Brown
View articletitled, The Retinoid X Receptor-Selective Retinoid, LGD1069, Down-regulates Cyclooxygenase-2 Expression in Human Breast Cells through Transcription Factor Crosstalk: Implications for Molecular-Based Chemoprevention
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Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells
Xiaoke Huang; Shan Chen; Li Xu; Yueqin Liu; Dilip K. Deb; Leonidas C. Platanias; Raymond C. Bergan
View articletitled, Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells
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Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice
Xiaolin Zi; Anne R. Simoneau
View articletitled, Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice
Supplementary data
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Selenium Disrupts Estrogen Signaling by Altering Estrogen Receptor Expression and Ligand Binding in Human Breast Cancer Cells
Soo Ok Lee; Nagalakshmi Nadiminty; Xiu Xian Wu; Wei Lou; Yan Dong; Clement Ip; Sergio A. Onate; Allen C. Gao
View articletitled, Selenium Disrupts Estrogen Signaling by Altering Estrogen Receptor Expression and Ligand Binding in Human Breast Cancer Cells
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Tamoxifen Inhibition of Estrogen Receptor-α–Negative Mouse Mammary Tumorigenesis
Daniel Medina; Frances S. Kittrell; Jamal Hill; Anne Shepard; Gudmundur Thordarson; Powel Brown
View articletitled, Tamoxifen Inhibition of Estrogen Receptor-α–Negative Mouse Mammary Tumorigenesis
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  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

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