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Issues

Volume 65, Issue 6
15 March 2005
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Review Article

ABL Oncogenes and Phosphoinositide 3-Kinase: Mechanism of Activation and Downstream Effectors
Michael G. Kharas; David A. Fruman
View articletitled, <em>ABL</em> Oncogenes and Phosphoinositide 3-Kinase: Mechanism of Activation and Downstream Effectors
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Priority Reports

Lower Induction of p53 and Decreased Apoptosis in NQO1-Null Mice Lead to Increased Sensitivity to Chemical-Induced Skin Carcinogenesis
Karim Iskander; Amos Gaikwad; Marilene Paquet; Delwin J. Long, II; Cory Brayton; Roberto Barrios; Anil K. Jaiswal
View articletitled, Lower Induction of p53 and Decreased Apoptosis in <em>NQO1</em>-Null Mice Lead to Increased Sensitivity to Chemical-Induced Skin Carcinogenesis
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The Antifolate Activity of Tea Catechins
Enma Navarro-Perán; Juan Cabezas-Herrera; Francisco García-Cánovas; Marcus C. Durrant; Roger N.F. Thorneley; José Neptuno Rodríguez-López
View articletitled, The Antifolate Activity of Tea Catechins
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Cell Type-Specific Tumor Suppression by Ink4a and Arf in Kras-Induced Mouse Gliomagenesis
Lene Uhrbom; Marianne Kastemar; Fredrik K. Johansson; Bengt Westermark; Eric C. Holland
View articletitled, Cell Type-Specific Tumor Suppression by <em>Ink4a</em> and <em>Arf</em> in Kras-Induced Mouse Gliomagenesis
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Genetic and Pharmacologic Identification of Akt as a Mediator of Brain-Derived Neurotrophic Factor/TrkB Rescue of Neuroblastoma Cells from Chemotherapy-Induced Cell Death
Zhijie Li; Jerry Jaboin; Phillip A. Dennis; Carol J. Thiele
View articletitled, Genetic and Pharmacologic Identification of Akt as a Mediator of Brain-Derived Neurotrophic Factor/TrkB Rescue of Neuroblastoma Cells from Chemotherapy-Induced Cell Death
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Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells
Andrei V. Ougolkov; Martin E. Fernandez-Zapico; Doris N. Savoy; Raul A. Urrutia; Daniel D. Billadeau
View articletitled, Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells
Supplementary data
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Androgen Causes Growth Suppression and Reversion of Androgen-Independent Prostate Cancer Xenografts to an Androgen-Stimulated Phenotype in Athymic Mice
Chih-pin Chuu; Richard A. Hiipakka; Junichi Fukuchi; John M. Kokontis; Shutsung Liao
View articletitled, Androgen Causes Growth Suppression and Reversion of Androgen-Independent Prostate Cancer Xenografts to an Androgen-Stimulated Phenotype in Athymic Mice
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Activated Ras Enhances Insulin-Like Growth Factor I Induction of Vascular Endothelial Growth Factor in Prostate Epithelial Cells
Mark Stearns; Jordan Tran; Mary Kay Francis; Hong Zhang; Christian Sell
View articletitled, Activated Ras Enhances Insulin-Like Growth Factor I Induction of Vascular Endothelial Growth Factor in Prostate Epithelial Cells
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Molecular Biology, Pathobiology, and Genetics

Extensive Chromosomal Instability in Rad51d-Deficient Mouse Cells
Phillip G. Smiraldo; Aaron M. Gruver; Joshua C. Osborn; Douglas L. Pittman
View articletitled, Extensive Chromosomal Instability in <em>Rad51d</em>-Deficient Mouse Cells
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C-Myc–Independent Restoration of Multiple Phenotypes by Two C-Myc Target Genes with Overlapping Functions
Krisiti Rothermund; Kenneth Rogulski; Elaine Fernandes; Amy Whiting; John Sedivy; Lixia Pu; Edward V. Prochownik
View articletitled, C-Myc–Independent Restoration of Multiple Phenotypes by Two C-Myc Target Genes with Overlapping Functions
Supplementary data
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Lack of Correlation between p53-Dependent Transcriptional Activity and the Ability to Induce Apoptosis among 179 Mutant p53s
Yuichi Kakudo; Hiroyuki Shibata; Kazunori Otsuka; Shunsuke Kato; Chikashi Ishioka
View articletitled, Lack of Correlation between p53-Dependent Transcriptional Activity and the Ability to Induce Apoptosis among 179 Mutant p53s
Supplementary data
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Discovery of Aberrant Expression of R-RAS by Cancer-Linked DNA Hypomethylation in Gastric Cancer Using Microarrays
Michiko Nishigaki; Kazuhiko Aoyagi; Inaho Danjoh; Masahide Fukaya; Kazuyoshi Yanagihara; Hiromi Sakamoto; Teruhiko Yoshida; Hiroki Sasaki
View articletitled, Discovery of Aberrant Expression of <em>R-RAS</em> by Cancer-Linked DNA Hypomethylation in Gastric Cancer Using Microarrays
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Apoptosis Factor EI24/PIG8 Is a Novel Endoplasmic Reticulum–Localized Bcl-2–Binding Protein which Is Associated with Suppression of Breast Cancer Invasiveness
Xiansi Zhao; Robert E. Ayer; Shannon L. Davis; Sarah J. Ames; Brian Florence; Cyrus Torchinsky; James S. Liou; Ling Shen; Remco A. Spanjaard
View articletitled, Apoptosis Factor EI24/PIG8 Is a Novel Endoplasmic Reticulum–Localized Bcl-2–Binding Protein which Is Associated with Suppression of Breast Cancer Invasiveness
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Functional Loss of the γ-Catenin Gene through Epigenetic and Genetic Pathways in Human Prostate Cancer
Hiroaki Shiina; Julia E. Breault; William W. Basset; Hideki Enokida; Shinji Urakami; Long-Cheng Li; Steven T. Okino; Masao Deguchi; Masanori Kaneuchi; Masaharu Terashima; Tatsuaki Yoneda; Kazushi Shigeno; Peter R. Carroll; Mikio Igawa; Rajvir Dahiya
View articletitled, Functional Loss of the <em>γ-Catenin</em> Gene through Epigenetic and Genetic Pathways in Human Prostate Cancer
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Loss of the Inactive X Chromosome and Replication of the Active X in BRCA1-Defective and Wild-type Breast Cancer Cells
Silvia M. Sirchia; Lisetta Ramoscelli; Francesca R. Grati; Floriana Barbera; Danila Coradini; Franca Rossella; Giovanni Porta; Elena Lesma; Anna Ruggeri; Paolo Radice; Giuseppe Simoni; Monica Miozzo
View articletitled, Loss of the Inactive X Chromosome and Replication of the Active X in <em>BRCA1</em>-Defective and Wild-type Breast Cancer Cells
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Molecular Staging of Cervical Lymph Nodes in Squamous Cell Carcinoma of the Head and Neck
Robert L. Ferris; Liqiang Xi; Siva Raja; Jennifer L. Hunt; Jun Wang; William E. Gooding; Lori Kelly; Jesus Ching; James D. Luketich; Tony E. Godfrey
View articletitled, Molecular Staging of Cervical Lymph Nodes in Squamous Cell Carcinoma of the Head and Neck
Supplementary data
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Cytoplasmic HuR Expression Is a Prognostic Factor in Invasive Ductal Breast Carcinoma
Mira Heinonen; Petri Bono; Kirsi Narko; Sung-Hee Chang; Johan Lundin; Heikki Joensuu; Henry Furneaux; Timothy Hla; Caj Haglund; Ari Ristimäki
View articletitled, Cytoplasmic HuR Expression Is a Prognostic Factor in Invasive Ductal Breast Carcinoma
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Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas
Ronny Drapkin; Hans Henning von Horsten; Yafang Lin; Samuel C. Mok; Christopher P. Crum; William R. Welch; Jonathan L. Hecht
View articletitled, Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas
Supplementary data
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Gene Expression Profiling Identifies Molecular Subtypes of Inflammatory Breast Cancer
François Bertucci; Pascal Finetti; Jacques Rougemont; Emmanuelle Charafe-Jauffret; Nathalie Cervera; Carole Tarpin; Catherine Nguyen; Luc Xerri; Rémi Houlgatte; Jocelyne Jacquemier; Patrice Viens; Daniel Birnbaum
View articletitled, Gene Expression Profiling Identifies Molecular Subtypes of Inflammatory Breast Cancer
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Immortalization of Primary Human Prostate Epithelial Cells by c-Myc
Jesús Gil; Preeti Kerai; Matilde Lleonart; David Bernard; Juan Cruz Cigudosa; Gordon Peters; Amancio Carnero; David Beach
View articletitled, Immortalization of Primary Human Prostate Epithelial Cells by c-Myc
Supplementary data
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p73β-Mediated Apoptosis Requires p57kip2 Induction and IEX-1 Inhibition
Susana Gonzalez; Manuel M. Perez-Perez; Eva Hernando; Manuel Serrano; Carlos Cordon-Cardo
View articletitled, p73β-Mediated Apoptosis Requires p57<sup>kip2</sup> Induction and IEX-1 Inhibition
Supplementary data
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Cell and Tumor Biology

Expression of the Carcinoembryonic Antigen Gene Is Inhibited by SOX9 in Human Colon Carcinoma Cells
Philippe Jay; Philippe Berta; Philippe Blache
View articletitled, Expression of the Carcinoembryonic Antigen Gene Is Inhibited by SOX9 in Human Colon Carcinoma Cells
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CDK4 and MDM2 Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-type INK4a/ARF Locus
Luis Hernández; Silvia Beà; Magda Pinyol; German Ott; Tiemo Katzenberger; Andreas Rosenwald; Francesc Bosch; Armando López-Guillermo; Jan Delabie; Dolors Colomer; Emili Montserrat; Elías Campo
View articletitled, <em>CDK4</em> and <em>MDM2</em> Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-type <em>INK4a/ARF</em> Locus
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Cancer/Testis Antigen Expression in Human Mesenchymal Stem Cells: Down-regulation of SSX Impairs Cell Migration and Matrix Metalloproteinase 2 Expression
Garth Cronwright; Katarina Le Blanc; Cecilia Götherström; Pádraig Darcy; Monika Ehnman; Bertha Brodin
View articletitled, Cancer/Testis Antigen Expression in Human Mesenchymal Stem Cells: Down-regulation of <em>SSX</em> Impairs Cell Migration and Matrix Metalloproteinase 2 Expression
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The E7 Protein of Cutaneous Human Papillomavirus Type 8 Causes Invasion of Human Keratinocytes into the Dermis in Organotypic Cultures of Skin
Baki Akgül; Ramón García-Escudero; Lucy Ghali; Herbert J. Pfister; Pawel G. Fuchs; Harshad Navsaria; Alan Storey
View articletitled, The E7 Protein of Cutaneous Human Papillomavirus Type 8 Causes Invasion of Human Keratinocytes into the Dermis in Organotypic Cultures of Skin
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Expression and Nuclear Location of the Transcriptional Repressor Kaiso Is Regulated by the Tumor Microenvironment
Adelheid Soubry; Jolanda van Hengel; Eef Parthoens; Cecile Colpaert; Eric Van Marck; David Waltregny; Albert B. Reynolds; Frans van Roy
View articletitled, Expression and Nuclear Location of the Transcriptional Repressor Kaiso Is Regulated by the Tumor Microenvironment
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Cyclooxygenase-2 Functions as a Downstream Mediator of Lysophosphatidic Acid to Promote Aggressive Behavior in Ovarian Carcinoma Cells
Jaime Symowicz; Brian P. Adley; Michelle M.M. Woo; Nelly Auersperg; Laurie G. Hudson; M. Sharon Stack
View articletitled, Cyclooxygenase-2 Functions as a Downstream Mediator of Lysophosphatidic Acid to Promote Aggressive Behavior in Ovarian Carcinoma Cells
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HYAL1 Hyaluronidase: A Molecular Determinant of Bladder Tumor Growth and Invasion
Vinata B. Lokeshwar; Wolfgang H. Cerwinka; Bal L. Lokeshwar
View articletitled, HYAL1 Hyaluronidase: A Molecular Determinant of Bladder Tumor Growth and Invasion
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Peroxisome Proliferator-Activated Receptor γ Inhibition Prevents Adhesion to the Extracellular Matrix and Induces Anoikis in Hepatocellular Carcinoma Cells
Katherine L. Schaefer; Koichiro Wada; Hirokazu Takahashi; Nobuyuki Matsuhashi; Shin Ohnishi; M. Michael Wolfe; Jerrold R. Turner; Atsushi Nakajima; Steven C. Borkan; Lawrence J. Saubermann
View articletitled, Peroxisome Proliferator-Activated Receptor γ Inhibition Prevents Adhesion to the Extracellular Matrix and Induces Anoikis in Hepatocellular Carcinoma Cells
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Tbx2 Is Overexpressed and Plays an Important Role in Maintaining Proliferation and Suppression of Senescence in Melanomas
Keith W. Vance; Suzanne Carreira; Gerald Brosch; Colin R. Goding
View articletitled, Tbx2 Is Overexpressed and Plays an Important Role in Maintaining Proliferation and Suppression of Senescence in Melanomas
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Dehydroepiandrosterone Can Inhibit the Proliferation of Myeloma Cells and the Interleukin-6 Production of Bone Marrow Mononuclear Cells from Patients with Myeloma
Shangqin Liu; Hideaki Ishikawa; Fu-Jun Li; Zi Ma; Ken-ichiro Otsuyama; Hideki Asaoku; Saeid Abroun; Xu Zheng; Naohiro Tsuyama; Masanori Obata; Michio M. Kawano
View articletitled, Dehydroepiandrosterone Can Inhibit the Proliferation of Myeloma Cells and the Interleukin-6 Production of Bone Marrow Mononuclear Cells from Patients with Myeloma
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Targeted Replacement of Hypoxia-Inducible Factor-1α by a Hypoxia-Inducible Factor-2α Knock-in Allele Promotes Tumor Growth
Kelly L. Covello; M. Celeste Simon; Brian Keith
View articletitled, Targeted Replacement of Hypoxia-Inducible Factor-1α by a Hypoxia-Inducible Factor-2α Knock-in Allele Promotes Tumor Growth
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Emodin Down-Regulates Androgen Receptor and Inhibits Prostate Cancer Cell Growth
Tai-Lung Cha; Lin Qiu; Chun-Te Chen; Yong Wen; Mien-Chie Hung
View articletitled, Emodin Down-Regulates Androgen Receptor and Inhibits Prostate Cancer Cell Growth
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Effect of Conditional Knockout of the Type II TGF-β Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis
Elizabeth Forrester; Anna Chytil; Brian Bierie; Mary Aakre; Agnieszka E. Gorska; Ali-Reza Sharif-Afshar; William J. Muller; Harold L. Moses
View articletitled, Effect of Conditional Knockout of the Type II <em>TGF-β</em> Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis
Supplementary data
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Human Osteocalcin and Bone Sialoprotein Mediating Osteomimicry of Prostate Cancer Cells: Role of cAMP-Dependent Protein Kinase A Signaling Pathway
Wen-Chin Huang; Zhihui Xie; Hiroyuki Konaka; Jaro Sodek; Haiyen E. Zhau; Leland W.K. Chung
View articletitled, Human Osteocalcin and Bone Sialoprotein Mediating Osteomimicry of Prostate Cancer Cells: Role of cAMP-Dependent Protein Kinase A Signaling Pathway
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IGFBP-3 Is a Direct Target of Transcriptional Regulation by ΔNp63α in Squamous Epithelium
Christopher E. Barbieri; Carmen A. Perez; Kimberly N. Johnson; Kim A. Ely; Dean Billheimer; Jennifer A. Pietenpol
View articletitled, IGFBP-3 Is a Direct Target of Transcriptional Regulation by ΔNp63α in Squamous Epithelium
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Reconstitution of Human Telomerase Reverse Transcriptase Expression Rescues Colorectal Carcinoma Cells from In vitro Senescence: Evidence against Immortality as a Constitutive Trait of Tumor Cells
Piero Dalerba; Cristiana Guiducci; Pietro Luigi Poliani; Ingrid Cifola; Mariella Parenza; Milo Frattini; Gianfrancesco Gallino; Ileana Carnevali; Ilvia Di Giulio; Salvatore Andreola; Claudia Lombardo; Licia Rivoltini; Tamás Schweighoffer; Filiberto Belli; Mario P. Colombo; Giorgio Parmiani; Chiara Castelli
View articletitled, Reconstitution of Human Telomerase Reverse Transcriptase Expression Rescues Colorectal Carcinoma Cells from <em>In vitro</em> Senescence: Evidence against Immortality as a Constitutive Trait of Tumor Cells
Supplementary data
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The Propeptide Mediates Formation of Stromal Stores of PROMIC-1: Role in Determining Prostate Cancer Outcome
Asne R. Bauskin; David A. Brown; Simon Junankar; Krishan K. Rasiah; Sarah Eggleton; Mark Hunter; Tao Liu; Dave Smith; Tamara Kuffner; Greg J. Pankhurst; Heiko Johnen; Pamela J. Russell; Wade Barret; Phillip D. Stricker; John J. Grygiel; James G. Kench; Susan M. Henshall; Robert L. Sutherland; Samuel N. Breit
View articletitled, The Propeptide Mediates Formation of Stromal Stores of PROMIC-1: Role in Determining Prostate Cancer Outcome
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Hair Follicle–Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin
Yasuyuki Amoh; Lingna Li; Meng Yang; Ping Jiang; Abdool R. Moossa; Kensei Katsuoka; Robert M. Hoffman
View articletitled, Hair Follicle–Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin
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Predominant Bcl-XL Knockdown Disables Antiapoptotic Mechanisms: Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Based Triple Chemotherapy Overcomes Chemoresistance in Pancreatic Cancer Cells In vitro
Jirong Bai; Jianhua Sui; Aram Demirjian; Charles M. Vollmer, Jr.; Wayne Marasco; Mark P. Callery
View articletitled, Predominant Bcl-XL Knockdown Disables Antiapoptotic Mechanisms: Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Based Triple Chemotherapy Overcomes Chemoresistance in Pancreatic Cancer Cells <em>In vitro</em>
Supplementary data
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Expression of Notch-1 and Its Ligands, Delta-Like-1 and Jagged-1, Is Critical for Glioma Cell Survival and Proliferation
Benjamin W. Purow; Raqeeb M. Haque; Martha W. Noel; Qin Su; Michael J. Burdick; Jeongwu Lee; Tilak Sundaresan; Sandra Pastorino; John K. Park; Irina Mikolaenko; Dragan Maric; Charles G. Eberhart; Howard A. Fine
View articletitled, Expression of Notch-1 and Its Ligands, Delta-Like-1 and Jagged-1, Is Critical for Glioma Cell Survival and Proliferation
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Modulation of Survival Signaling Pathways and Persistence of the Genotoxic Stress as a Basis for the Synergistic Interaction between the Atypical Retinoid ST1926 and the Epidermal Growth Factor Receptor Inhibitor ZD1839
Chiara Zanchi; Valentina Zuco; Cinzia Lanzi; Rosanna Supino; Franco Zunino
View articletitled, Modulation of Survival Signaling Pathways and Persistence of the Genotoxic Stress as a Basis for the Synergistic Interaction between the Atypical Retinoid ST1926 and the Epidermal Growth Factor Receptor Inhibitor ZD1839
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Selective Apoptotic Killing of Malignant Hemopoietic Cells by Antibody-Targeted Delivery of an Amphipathic Peptide
Alexandra J. Marks; Margaret S. Cooper; Robert J. Anderson; Kim H. Orchard; Geoffrey Hale; Janet M. North; Kanagasabai Ganeshaguru; Andrew J. Steele; Atul B. Mehta; Mark W. Lowdell; R. Gitendra Wickremasinghe
View articletitled, Selective Apoptotic Killing of Malignant Hemopoietic Cells by Antibody-Targeted Delivery of an Amphipathic Peptide
Supplementary data
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Increased Expression of Apoptosis Inhibitor Protein XIAP Contributes to Anoikis Resistance of Circulating Human Prostate Cancer Metastasis Precursor Cells
Olga Berezovskaya; Aaron D. Schimmer; Anna B. Glinskii; Clemencia Pinilla; Robert M. Hoffman; John C. Reed; Gennadi V. Glinsky
View articletitled, Increased Expression of Apoptosis Inhibitor Protein XIAP Contributes to Anoikis Resistance of Circulating Human Prostate Cancer Metastasis Precursor Cells
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The Tumor Bed Effect: Increased Metastatic Dissemination from Hypoxia-Induced Up-regulation of Metastasis-Promoting Gene Products
Einar K. Rofstad; Berit Mathiesen; Kristin Henriksen; Kristil Kindem; Kanthi Galappathi
View articletitled, The Tumor Bed Effect: Increased Metastatic Dissemination from Hypoxia-Induced Up-regulation of Metastasis-Promoting Gene Products
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The Seco-Taxane IDN5390 Is Able to Target Class III β-Tubulin and to Overcome Paclitaxel Resistance
Cristiano Ferlini; Giuseppina Raspaglio; Simona Mozzetti; Lucia Cicchillitti; Flavia Filippetti; Daniela Gallo; Caterina Fattorusso; Giuseppe Campiani; Giovanni Scambia
View articletitled, The Seco-Taxane IDN5390 Is Able to Target Class III β-Tubulin and to Overcome Paclitaxel Resistance
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Rapamycin Inhibits Ezrin-Mediated Metastatic Behavior in a Murine Model of Osteosarcoma
Xiaolin Wan; Arnulfo Mendoza; Chand Khanna; Lee J. Helman
View articletitled, Rapamycin Inhibits Ezrin-Mediated Metastatic Behavior in a Murine Model of Osteosarcoma
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Mutant V599EB-Raf Regulates Growth and Vascular Development of Malignant Melanoma Tumors
Arati Sharma; Nishit R. Trivedi; Melissa A. Zimmerman; David A. Tuveson; Charles D. Smith; Gavin P. Robertson
View articletitled, Mutant <sup>V599E</sup>B-Raf Regulates Growth and Vascular Development of Malignant Melanoma Tumors
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Coadministration of Histone Deacetylase Inhibitors and Perifosine Synergistically Induces Apoptosis in Human Leukemia Cells through Akt and ERK1/2 Inactivation and the Generation of Ceramide and Reactive Oxygen Species
Mohamed Rahmani; Erin Reese; Yun Dai; Cheryl Bauer; Shawn G. Payne; Paul Dent; Sarah Spiegel; Steven Grant
View articletitled, Coadministration of Histone Deacetylase Inhibitors and Perifosine Synergistically Induces Apoptosis in Human Leukemia Cells through Akt and ERK1/2 Inactivation and the Generation of Ceramide and Reactive Oxygen Species
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Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells
Eddy Pasquier; Stéphane Honore; Bertrand Pourroy; Mary Ann Jordan; Maxime Lehmann; Claudette Briand; Diane Braguer
View articletitled, Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells
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Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype
Johannes V. Swinnen; Annelies Beckers; Koen Brusselmans; Sophie Organe; Joanna Segers; Leen Timmermans; Frank Vanderhoydonc; Ludo Deboel; Rita Derua; Etienne Waelkens; Ellen De Schrijver; Tine Van de Sande; Agnès Noël; Fabienne Foufelle; Guido Verhoeven
View articletitled, Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype
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Immunology

Administration of IFN-α Enhances the Efficacy of a Granulocyte Macrophage Colony Stimulating Factor–Secreting Tumor Cell Vaccine
Rodney A. Prell; Betty Li; Jian Min Lin; Melinda VanRoey; Karin Jooss
View articletitled, Administration of IFN-α Enhances the Efficacy of a Granulocyte Macrophage Colony Stimulating Factor–Secreting Tumor Cell Vaccine
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Increased Populations of Regulatory T Cells in Peripheral Blood of Patients with Hepatocellular Carcinoma
Lars A. Ormandy; Tina Hillemann; Heiner Wedemeyer; Michael P. Manns; Tim F. Greten; Firouzeh Korangy
View articletitled, Increased Populations of Regulatory T Cells in Peripheral Blood of Patients with Hepatocellular Carcinoma
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Endocrinology

Conditional BRAFV600E Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells
Norisato Mitsutake; Jeffrey A. Knauf; Shin Mitsutake; Cleo Mesa, Jr.; Lei Zhang; James A. Fagin
View articletitled, Conditional BRAF<sup>V600E</sup> Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells
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Clinical Research

Estrogen Enhances whereas Tamoxifen Retards Development of Tsc Mouse Liver Hemangioma: A Tumor Related to Renal Angiomyolipoma and Pulmonary Lymphangioleiomyomatosis
Nisreen El-Hashemite; Victoria Walker; David J. Kwiatkowski
View articletitled, Estrogen Enhances whereas Tamoxifen Retards Development of Tsc Mouse Liver Hemangioma: A Tumor Related to Renal Angiomyolipoma and Pulmonary Lymphangioleiomyomatosis
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Epidemiology and Prevention

Methylenetetrahydrofolate Reductase Polymorphisms and Therapy Response in Pediatric Acute Lymphoblastic Leukemia
Richard Aplenc; Jennifer Thompson; Peggy Han; Mei La; Huaqing Zhao; Beverly Lange; Timothy Rebbeck
View articletitled, Methylenetetrahydrofolate Reductase Polymorphisms and Therapy Response in Pediatric Acute Lymphoblastic Leukemia
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19-Nor-1,25(OH)2D2 (a Novel, Noncalcemic Vitamin D Analogue), Combined with Arsenic Trioxide, Has Potent Antitumor Activity against Myeloid Leukemia
Takashi Kumagai; Lee-Yung Shih; Susan V. Hughes; Julian C. Desmond; James O'Kelly; Martin Hewison; H. Phillip Koeffler
View articletitled, 19-Nor-1,25(OH)<sub>2</sub>D<sub>2</sub> (a Novel, Noncalcemic Vitamin D Analogue), Combined with Arsenic Trioxide, Has Potent Antitumor Activity against Myeloid Leukemia
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Manganese Superoxide Dismutase Polymorphism, Prediagnostic Antioxidant Status, and Risk of Clinical Significant Prostate Cancer
Haojie Li; Philip W. Kantoff; Edward Giovannucci; Michael F. Leitzmann; J. Michael Gaziano; Meir J. Stampfer; Jing Ma
View articletitled, Manganese Superoxide Dismutase Polymorphism, Prediagnostic Antioxidant Status, and Risk of Clinical Significant Prostate Cancer
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Correction

STAT3, TFF3, VEGFR in Colon Cancer Cells
View articletitled, <em>STAT3</em>, <em>TFF3</em>, <em>VEGFR</em> in Colon Cancer Cells
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