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Issues

Volume 65, Issue 4
15 February 2005
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Meeting Report

Molecular Target-Based Treatment of Human Cancer: Summary of the 10th International Conference on Differentiation Therapy
Arthur Zelent; Kevin Petrie; Zhu Chen; Reuben Lotan; Michael Lübbert; Martin S. Tallman; Ryuzo Ohno; Laurent Degos; Samuel Waxman
View articletitled, Molecular Target-Based Treatment of Human Cancer: Summary of the 10th International Conference on Differentiation Therapy
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Priority Reports

Osterix, a Transcription Factor for Osteoblast Differentiation, Mediates Antitumor Activity in Murine Osteosarcoma
Ying Cao; Zhichao Zhou; Benoit de Crombrugghe; Kazuhisa Nakashima; Hui Guan; Xiaoping Duan; Shu-Fang Jia; Eugenie S. Kleinerman
View articletitled, Osterix, a Transcription Factor for Osteoblast Differentiation, Mediates Antitumor Activity in Murine Osteosarcoma
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Bone Marrow Mesenchymal Stem Cells Provide an Alternate Pathway of Osteoclast Activation and Bone Destruction by Cancer Cells
Yasuyoshi Sohara; Hiroyuki Shimada; Cedric Minkin; Anat Erdreich-Epstein; Jan A. Nolta; Yves A. DeClerck
View articletitled, Bone Marrow Mesenchymal Stem Cells Provide an Alternate Pathway of Osteoclast Activation and Bone Destruction by Cancer Cells
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Effects of DNA Methylation on Galectin-3 Expression in Pituitary Tumors
Katharina H. Ruebel; Long Jin; Xiang Qian; Bernd W. Scheithauer; Kalman Kovacs; Nobuki Nakamura; Heyu Zhang; Avraham Raz; Ricardo V. Lloyd
View articletitled, Effects of DNA Methylation on Galectin-3 Expression in Pituitary Tumors
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Circulating Tumor-Specific DNA: A Marker for Monitoring Efficacy of Adjuvant Therapy in Cancer Patients
Heidi Fiegl; Simone Millinger; Elisabeth Mueller-Holzner; Christian Marth; Christian Ensinger; Andreas Berger; Helmut Klocker; Georg Goebel; Martin Widschwendter
View articletitled, Circulating Tumor-Specific DNA: A Marker for Monitoring Efficacy of Adjuvant Therapy in Cancer Patients
Supplementary data
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Haploinsufficiency for Odc Modifies Mouse Skin Tumor Susceptibility
Yongjun Guo; John L. Cleveland; Thomas G. O'Brien
View articletitled, Haploinsufficiency for <em>Odc</em> Modifies Mouse Skin Tumor Susceptibility
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Molecular Biology, Pathobiology, and Genetics

Differential Expression of Cell Cycle Regulators in Phenotypic Variants of Transgenically Induced Bladder Tumors: Implications for Tumor Behavior
Antonio Garcia-España; Edgard Salazar; Tung-Tien Sun; Xue-Ru Wu; Angel Pellicer
View articletitled, Differential Expression of Cell Cycle Regulators in Phenotypic Variants of Transgenically Induced Bladder Tumors: Implications for Tumor Behavior
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NFBD1/Mdc1 Mediates ATR-Dependent DNA Damage Response
Aimin Peng; Phang-Lang Chen
View articletitled, NFBD1/Mdc1 Mediates ATR-Dependent DNA Damage Response
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Deletion, Methylation, and Expression of the NKX3.1 Suppressor Gene in Primary Human Prostate Cancer
Ekatherine Asatiani; Wen-Xin Huang; Antai Wang; Elizabeth Rodriguez Ortner; Luciane R. Cavalli; Bassem R. Haddad; Edward P. Gelmann
View articletitled, Deletion, Methylation, and Expression of the <em>NKX3.1</em> Suppressor Gene in Primary Human Prostate Cancer
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Genomic Organization of Amplified MYC Genes Suggests Distinct Mechanisms of Amplification in Tumorigenesis
John Herrick; Chiara Conti; Sebastien Teissier; Francoise Thierry; Jérôme Couturier; Xavier Sastre-Garau; Michel Favre; Gérard Orth; Aaron Bensimon
View articletitled, Genomic Organization of Amplified <em>MYC</em> Genes Suggests Distinct Mechanisms of Amplification in Tumorigenesis
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Multiphoton Microscopy of Endogenous Fluorescence Differentiates Normal, Precancerous, and Cancerous Squamous Epithelial Tissues
Melissa C. Skala; Jayne M. Squirrell; Kristin M. Vrotsos; Jens C. Eickhoff; Annette Gendron-Fitzpatrick; Kevin W. Eliceiri; Nirmala Ramanujam
View articletitled, Multiphoton Microscopy of Endogenous Fluorescence Differentiates Normal, Precancerous, and Cancerous Squamous Epithelial Tissues
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A Novel Transgenic Mouse Model Reveals Humanlike Regulation of an 8-kbp Human TERT Gene Promoter Fragment in Normal and Tumor Tissues
Julia M. Ritz; Olaf Kühle; Sabine Riethdorf; Bence Sipos; Wolfgang Deppert; Christoph Englert; Cagatay Günes
View articletitled, A Novel Transgenic Mouse Model Reveals Humanlike Regulation of an 8-kbp Human <em>TERT</em> Gene Promoter Fragment in Normal and Tumor Tissues
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p53CSV, a Novel p53-Inducible Gene Involved in the p53-Dependent Cell-Survival Pathway
Woong-Ryeon Park; Yusuke Nakamura
View articletitled, <em>p53CSV</em>, a Novel p53-Inducible Gene Involved in the p53-Dependent Cell-Survival Pathway
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Reduced FEZ1/LZTS1 Expression and Outcome Prediction in Lung Cancer
Daisuke Nonaka; Alessandra Fabbri; Luca Roz; Luigi Mariani; Andrea Vecchione; G. William Moore; Luca Tavecchio; Carlo M. Croce; Gabriella Sozzi
View articletitled, Reduced FEZ1/LZTS1 Expression and Outcome Prediction in Lung Cancer
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A Germline DNA Polymorphism Enhances Alternative Splicing of the KLF6 Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk
Goutham Narla; Analisa DiFeo; Helen L. Reeves; Daniel J. Schaid; Jennifer Hirshfeld; Eldad Hod; Amanda Katz; William B. Isaacs; Scott Hebbring; Akira Komiya; Shannon K. McDonnell; Kathleen E. Wiley; Steven J. Jacobsen; Sarah D. Isaacs; Patrick C. Walsh; S. Lilly Zheng; Bao-Li Chang; Danielle M. Friedrichsen; Janet L. Stanford; Elaine A. Ostrander; Arul M. Chinnaiyan; Mark A. Rubin; Jianfeng Xu; Stephen N. Thibodeau; Scott L. Friedman; John A. Martignetti
View articletitled, A Germline DNA Polymorphism Enhances Alternative Splicing of the <em>KLF6</em> Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk
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p53 Modulates RPA-Dependent and RPA-Independent WRN Helicase Activity
Joshua A. Sommers; Sudha Sharma; Kevin M. Doherty; Parimal Karmakar; Qin Yang; Mark K. Kenny; Curtis C. Harris; Robert M. Brosh, Jr.
View articletitled, p53 Modulates RPA-Dependent and RPA-Independent WRN Helicase Activity
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Fate of Premalignant Clones during the Asymptomatic Phase Preceding Lymphoid Malignancy
Vincent Moulés; Carole Pomier; David Sibon; Anne-Sophie Gabet; Michal Reichert; Pierre Kerkhofs; Luc Willems; Franck Mortreux; Eric Wattel
View articletitled, Fate of Premalignant Clones during the Asymptomatic Phase Preceding Lymphoid Malignancy
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Oncogenic K-RAS Is Required to Maintain Changes in Cytoskeletal Organization, Adhesion, and Motility in Colon Cancer Cells
Claire B. Pollock; Senji Shirasawa; Takehiko Sasazuki; Walter Kolch; Amardeep S. Dhillon
View articletitled, Oncogenic <em>K-RAS</em> Is Required to Maintain Changes in Cytoskeletal Organization, Adhesion, and Motility in Colon Cancer Cells
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Altered Gene Expression Patterns in MCF-7 Cells Induced by the Urban Dust Particulate Complex Mixture Standard Reference Material 1649a
Brinda Mahadevan; Channa Keshava; Tamara Musafia-Jeknic; Arta Pecaj; Ainsley Weston; William M. Baird
View articletitled, Altered Gene Expression Patterns in MCF-7 Cells Induced by the Urban Dust Particulate Complex Mixture Standard Reference Material 1649a
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Distal Chr 4 Harbors a Genetic Locus (Gct1) Fundamental for Spontaneous Ovarian Granulosa Cell Tumorigenesis in a Mouse Model
Ann M. Dorward; Kathryn L. Shultz; Lindsay G. Horton; Renhua Li; Gary A. Churchill; Wesley G. Beamer
View articletitled, Distal Chr 4 Harbors a Genetic Locus (<em>Gct1</em>) Fundamental for Spontaneous Ovarian Granulosa Cell Tumorigenesis in a Mouse Model
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Susceptibility to Aflatoxin B1-Induced Carcinogenesis Correlates with Tissue-Specific Differences in DNA Repair Activity in Mouse and in Rat
Leanne L. Bedard; Manlio Alessi; Scott Davey; Thomas E. Massey
View articletitled, Susceptibility to Aflatoxin B<sub>1</sub>-Induced Carcinogenesis Correlates with Tissue-Specific Differences in DNA Repair Activity in Mouse and in Rat
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Generation and Molecular Characterization of Head and Neck Squamous Cell Lines of Fanconi Anemia Patients
Hester J.T. van Zeeburg; Peter J.F. Snijders; Gerard Pals; Mario A.J.A. Hermsen; Martin A. Rooimans; Grover Bagby; Jean Soulier; Eliane Gluckman; Johan Wennerberg; C. René Leemans; Hans Joenje; Ruud H. Brakenhoff
View articletitled, Generation and Molecular Characterization of Head and Neck Squamous Cell Lines of Fanconi Anemia Patients
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Interplay of RUNX1/MTG8 and DNA Methyltransferase 1 in Acute Myeloid Leukemia
Shujun Liu; Tiansheng Shen; Lenguyen Huynh; Marko I. Klisovic; Laura J. Rush; Jamie L. Ford; Jianhua Yu; Brian Becknell; Yu Li; Chunhui Liu; Tamara Vukosavljevic; Susan P. Whitman; Kun-Sang Chang; John C. Byrd; Danilo Perrotti; Christoph Plass; Guido Marcucci
View articletitled, Interplay of RUNX1/MTG8 and DNA Methyltransferase 1 in Acute Myeloid Leukemia
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Cell and Tumor Biology

Ron Receptor Signaling Augments Mammary Tumor Formation and Metastasis in a Murine Model of Breast Cancer
Belinda E. Peace; Kenya Toney-Earley; Margaret H. Collins; Susan E. Waltz
View articletitled, Ron Receptor Signaling Augments Mammary Tumor Formation and Metastasis in a Murine Model of Breast Cancer
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Angiogenesis Inhibition by Vascular Endothelial Growth Factor Receptor-2 Blockade Reduces Stromal Matrix Metalloproteinase Expression, Normalizes Stromal Tissue, and Reverts Epithelial Tumor Phenotype in Surface Heterotransplants
Silvia Vosseler; Nicolae Mirancea; Peter Bohlen; Margareta M. Mueller; Norbert E. Fusenig
View articletitled, Angiogenesis Inhibition by Vascular Endothelial Growth Factor Receptor-2 Blockade Reduces Stromal Matrix Metalloproteinase Expression, Normalizes Stromal Tissue, and Reverts Epithelial Tumor Phenotype in Surface Heterotransplants
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Insertion of c-Myc into Igh Induces B-Cell and Plasma-Cell Neoplasms in Mice
Sung Sup Park; Joong Su Kim; Lino Tessarollo; James D. Owens; Liangping Peng; Seong Su Han; Seung Tae Chung; Ted A. Torrey; Wan C. Cheung; Roberto D. Polakiewicz; Nicole McNeil; Thomas Ried; J. Frederic Mushinski; Herbert C. Morse, III; Siegfried Janz
View articletitled, Insertion of c-<em>Myc</em> into <em>Igh</em> Induces B-Cell and Plasma-Cell Neoplasms in Mice
Supplementary data
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Increased Expression of the E3-Ubiquitin Ligase Receptor Subunit βTRCP1 Relates to Constitutive Nuclear Factor-κB Activation and Chemoresistance in Pancreatic Carcinoma Cells
Susanne Müerköster; Alexander Arlt; Bence Sipos; Maike Witt; Maike Großmann; Günter Klöppel; Holger Kalthoff; Ulrich R. Fölsch; Heiner Schäfer
View articletitled, Increased Expression of the E3-Ubiquitin Ligase Receptor Subunit βTRCP1 Relates to Constitutive Nuclear Factor-κB Activation and Chemoresistance in Pancreatic Carcinoma Cells
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Dipeptidyl Peptidase Inhibits Malignant Phenotype of Prostate Cancer Cells by Blocking Basic Fibroblast Growth Factor Signaling Pathway
Umadevi V. Wesley; Michelle McGroarty; Asal Homoyouni
View articletitled, Dipeptidyl Peptidase Inhibits Malignant Phenotype of Prostate Cancer Cells by Blocking Basic Fibroblast Growth Factor Signaling Pathway
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Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior
Valerie G. Brunton; Egle Avizienyte; Valerie J. Fincham; Bryan Serrels; Chester A. Metcalf, III; Tomi K. Sawyer; Margaret C. Frame
View articletitled, Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior
Supplementary data
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Cytoplasmic Domain of proEGF Affects Distribution and Post-Translational Modification of Microtubuli and Increases Microtubule-Associated Proteins 1b and 2 Production in Human Thyroid Carcinoma Cells
Janette Pyka; Aleksandra Glogowska; Henning Dralle; Cuong Hoang-Vu; Thomas Klonisch
View articletitled, Cytoplasmic Domain of proEGF Affects Distribution and Post-Translational Modification of Microtubuli and Increases Microtubule-Associated Proteins 1b and 2 Production in Human Thyroid Carcinoma Cells
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Angiogenin Is Translocated to the Nucleus of HeLa Cells and Is Involved in Ribosomal RNA Transcription and Cell Proliferation
Takanori Tsuji; Yeqing Sun; Koji Kishimoto; Karen A. Olson; Shumei Liu; Saori Hirukawa; Guo-fu Hu
View articletitled, Angiogenin Is Translocated to the Nucleus of HeLa Cells and Is Involved in Ribosomal RNA Transcription and Cell Proliferation
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Mitotic Infidelity and Centrosome Duplication Errors in Cells Overexpressing Tripeptidyl-Peptidase II
Vaia Stavropoulou; Jianjun Xie; Marie Henriksson; Birgitta Tomkinson; Stefan Imreh; Maria G. Masucci
View articletitled, Mitotic Infidelity and Centrosome Duplication Errors in Cells Overexpressing Tripeptidyl-Peptidase II
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Development of Magnetic Resonance Imaging Contrast Material for In vivo Mapping of Tissue Transglutaminase Activity
Galit Mazooz; Tevie Mehlman; Thung-Shen Lai; Charles S. Greenberg; Mark W. Dewhirst; Michal Neeman
View articletitled, Development of Magnetic Resonance Imaging Contrast Material for <em>In vivo</em> Mapping of Tissue Transglutaminase Activity
Supplementary data
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Visualizing Chromosomes as Transcriptome Correlation Maps: Evidence of Chromosomal Domains Containing Co-expressed Genes—A Study of 130 Invasive Ductal Breast Carcinomas
Fabien Reyal; Nicolas Stransky; Isabelle Bernard-Pierrot; Anne Vincent-Salomon; Yann de Rycke; Paul Elvin; Andrew Cassidy; Alexander Graham; Carolyn Spraggon; Yoann Désille; Alain Fourquet; Claude Nos; Pierre Pouillart; Henri Magdelénat; Dominique Stoppa-Lyonnet; Jérôme Couturier; Brigitte Sigal-Zafrani; Bernard Asselain; Xavier Sastre-Garau; Olivier Delattre; Jean Paul Thiery; François Radvanyi
View articletitled, Visualizing Chromosomes as Transcriptome Correlation Maps: Evidence of Chromosomal Domains Containing Co-expressed Genes—A Study of 130 Invasive Ductal Breast Carcinomas
Supplementary data
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Cleavable ErbB4 Isoform in Estrogen Receptor–Regulated Growth of Breast Cancer Cells
Teemu T. Junttila; Maria Sundvall; Mikael Lundin; Johan Lundin; Minna Tanner; Pirkko Härkönen; Heikki Joensuu; Jorma Isola; Klaus Elenius
View articletitled, Cleavable ErbB4 Isoform in Estrogen Receptor–Regulated Growth of Breast Cancer Cells
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Development of Skin Tumors in Mice Transgenic for Early Genes of Human Papillomavirus Type 8
Inke Diana Schaper; Gian Paolo Marcuzzi; Sönke Jan Weissenborn; Hans Udo Kasper; Volker Dries; Neil Smyth; Pawel Fuchs; Herbert Pfister
View articletitled, Development of Skin Tumors in Mice Transgenic for Early Genes of Human Papillomavirus Type 8
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A Mechanism-Based Antioxidant Approach for the Reduction of Skin Carcinogenesis
Yunfeng Zhao; Luksana Chaiswing; Terry D. Oberley; Ines Batinic-Haberle; William St. Clair; Charles J. Epstein; Daret St. Clair
View articletitled, A Mechanism-Based Antioxidant Approach for the Reduction of Skin Carcinogenesis
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PTEN and Hypoxia Regulate Tissue Factor Expression and Plasma Coagulation by Glioblastoma
Yuan Rong; Dawn E. Post; Russell O. Pieper; Donald L. Durden; Erwin G. Van Meir; Daniel J. Brat
View articletitled, PTEN and Hypoxia Regulate Tissue Factor Expression and Plasma Coagulation by Glioblastoma
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The Homeobox Gene Gax Inhibits Angiogenesis through Inhibition of Nuclear Factor-κB–Dependent Endothelial Cell Gene Expression
Sejal Patel; Alejandro D. Leal; David H. Gorski
View articletitled, The Homeobox Gene <em>Gax</em> Inhibits Angiogenesis through Inhibition of Nuclear Factor-κB–Dependent Endothelial Cell Gene Expression
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Characterizing Extravascular Fluid Transport of Macromolecules in the Tumor Interstitium by Magnetic Resonance Imaging
Arvind P. Pathak; Dmitri Artemov; B. Douglas Ward; David G. Jackson; Michal Neeman; Zaver M. Bhujwalla
View articletitled, Characterizing Extravascular Fluid Transport of Macromolecules in the Tumor Interstitium by Magnetic Resonance Imaging
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Protein Kinase C ζ Is Required for Epidermal Growth Factor–Induced Chemotaxis of Human Breast Cancer Cells
Ronghua Sun; Ping Gao; Lin Chen; Dalong Ma; Jiming Wang; Joost J. Oppenheim; Ning Zhang
View articletitled, Protein Kinase C ζ Is Required for Epidermal Growth Factor–Induced Chemotaxis of Human Breast Cancer Cells
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Leukemic Stem Cells in Childhood High-Risk ALL/t(9;22) and t(4;11) Are Present in Primitive Lymphoid-Restricted CD34+CD19− Cells
Marc Hotfilder; Silja Röttgers; Annegret Rosemann; André Schrauder; Martin Schrappe; Rob Pieters; Heribert Jürgens; Jochen Harbott; Josef Vormoor
View articletitled, Leukemic Stem Cells in Childhood High-Risk ALL/t(9;22) and t(4;11) Are Present in Primitive Lymphoid-Restricted CD34<sup>+</sup>CD19<sup>−</sup> Cells
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Mitotic Arrest Deficient 2 Expression Induces Chemosensitization to a DNA-Damaging Agent, Cisplatin, in Nasopharyngeal Carcinoma Cells
Hiu Wing Cheung; Dong-Yan Jin; Ming-tat Ling; Yong Chuan Wong; Qi Wang; Sai Wah Tsao; Xianghong Wang
View articletitled, Mitotic Arrest Deficient 2 Expression Induces Chemosensitization to a DNA-Damaging Agent, Cisplatin, in Nasopharyngeal Carcinoma Cells
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Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects
Laura P. Stabile; Jennifer S. Lyker; Christopher T. Gubish; Weiping Zhang; Jennifer R. Grandis; Jill M. Siegfried
View articletitled, Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects
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Quantitative Immuno-Positron Emission Tomography Imaging of HER2-Positive Tumor Xenografts with an Iodine-124 Labeled Anti-HER2 Diabody
Matthew K. Robinson; Mohan Doss; Calvin Shaller; Deepa Narayanan; James D. Marks; Lee P. Adler; Dinko E. González Trotter; Gregory P. Adams
View articletitled, Quantitative Immuno-Positron Emission Tomography Imaging of HER2-Positive Tumor Xenografts with an Iodine-124 Labeled Anti-HER2 Diabody
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Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer
Patrick C. Ma; Ramasamy Jagadeeswaran; Simha Jagadeesh; Maria S. Tretiakova; Vidya Nallasura; Edward A. Fox; Mark Hansen; Erik Schaefer; Katsuhiko Naoki; Alan Lader; William Richards; David Sugarbaker; Aliya N. Husain; James G. Christensen; Ravi Salgia
View articletitled, Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer
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The G-Quadruplex-Interactive Molecule BRACO-19 Inhibits Tumor Growth, Consistent with Telomere Targeting and Interference with Telomerase Function
Angelika M. Burger; Fangping Dai; Christoph M. Schultes; Anthony P. Reszka; Michael J. Moore; John A. Double; Stephen Neidle
View articletitled, The G-Quadruplex-Interactive Molecule BRACO-19 Inhibits Tumor Growth, Consistent with Telomere Targeting and Interference with Telomerase Function
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Inhibition of Integrin-Linked Kinase by a Selective Small Molecule Inhibitor, QLT0254, Inhibits the PI3K/PKB/mTOR, Stat3, and FKHR Pathways and Tumor Growth, and Enhances Gemcitabine-Induced Apoptosis in Human Orthotopic Primary Pancreatic Cancer Xenografts
Cindy Y.F. Yau; Jeffery J. Wheeler; Kymberley L. Sutton; David W. Hedley
View articletitled, Inhibition of Integrin-Linked Kinase by a Selective Small Molecule Inhibitor, QLT0254, Inhibits the PI3K/PKB/mTOR, Stat3, and FKHR Pathways and Tumor Growth, and Enhances Gemcitabine-Induced Apoptosis in Human Orthotopic Primary Pancreatic Cancer Xenografts
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Histone Deacetylase Inhibitor Valproic Acid Enhances the Cytokine-Induced Expansion of Human Hematopoietic Stem Cells
Lidia De Felice; Caterina Tatarelli; Maria Grazia Mascolo; Chiara Gregorj; Francesca Agostini; Roberto Fiorini; Vania Gelmetti; Simona Pascale; Fabrizio Padula; Maria Teresa Petrucci; William Arcese; Clara Nervi
View articletitled, Histone Deacetylase Inhibitor Valproic Acid Enhances the Cytokine-Induced Expansion of Human Hematopoietic Stem Cells
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Inhibitory Anti-FLT3 Antibodies Are Capable of Mediating Antibody-Dependent Cell-Mediated Cytotoxicity and Reducing Engraftment of Acute Myelogenous Leukemia Blasts in Nonobese Diabetic/Severe Combined Immunodeficient Mice
Obdulio Piloto; Mark Levis; David Huso; Yiwen Li; Hongli Li; Mei-Nai Wang; Rajiv Bassi; Paul Balderes; Dale L. Ludwig; Larry Witte; Zhenping Zhu; Daniel J. Hicklin; Donald Small
View articletitled, Inhibitory Anti-FLT3 Antibodies Are Capable of Mediating Antibody-Dependent Cell-Mediated Cytotoxicity and Reducing Engraftment of Acute Myelogenous Leukemia Blasts in Nonobese Diabetic/Severe Combined Immunodeficient Mice
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Virus-Associated RNA I–Deleted Adenovirus, a Potential Oncolytic Agent Targeting EBV-Associated Tumors
Yaohe Wang; Shao-An Xue; Gunnel Hallden; Jennelle Francis; Ming Yuan; Beverly E. Griffin; Nick R. Lemoine
View articletitled, Virus-Associated RNA I–Deleted Adenovirus, a Potential Oncolytic Agent Targeting EBV-Associated Tumors
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Oncolytic Herpes Simplex Virus Vector Therapy of Breast Cancer in C3(1)/SV40 T-antigen Transgenic Mice
Renbin Liu; Susan Varghese; Samuel D. Rabkin
View articletitled, Oncolytic Herpes Simplex Virus Vector Therapy of Breast Cancer in C3(1)/SV40 T-antigen Transgenic Mice
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Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance
Yoichi Nakamura; Mikio Oka; Hiroshi Soda; Ken Shiozawa; Megumi Yoshikawa; Akiko Itoh; Yoji Ikegami; Junji Tsurutani; Katsumi Nakatomi; Takeshi Kitazaki; Seiji Doi; Hisahiro Yoshida; Shigeru Kohno
View articletitled, Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance
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Induction of Apoptosis in Primary Meningioma Cultures by Fenretinide
Vinay K. Puduvalli; Jessica T. Li; Ling Chen; Ian E. McCutcheon
View articletitled, Induction of Apoptosis in Primary Meningioma Cultures by Fenretinide
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Expression Profiling of Homocysteine Junction Enzymes in the NCI60 Panel of Human Cancer Cell Lines
Wen Zhang; Aaron Braun; Zachary Bauman; Horatiu Olteanu; Peter Madzelan; Ruma Banerjee
View articletitled, Expression Profiling of Homocysteine Junction Enzymes in the NCI60 Panel of Human Cancer Cell Lines
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Thiazolidenediones Mediate Apoptosis in Prostate Cancer Cells in Part through Inhibition of Bcl-xL/Bcl-2 Functions Independently of PPARγ
Chung-Wai Shiau; Chih-Cheng Yang; Samuel K. Kulp; Kuen-Feng Chen; Chang-Shi Chen; Jui-Wen Huang; Ching-Shih Chen
View articletitled, Thiazolidenediones Mediate Apoptosis in Prostate Cancer Cells in Part through Inhibition of Bcl-xL/Bcl-2 Functions Independently of PPARγ
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Immunology

Simultaneous Generation of CD8+ and CD4+ Melanoma-Reactive T Cells by Retroviral-Mediated Transfer of a Single T-Cell Receptor
Jeffrey J. Roszkowski; Gretchen E. Lyons; W. Martin Kast; Cassian Yee; Koen Van Besien; Michael I. Nishimura
View articletitled, Simultaneous Generation of CD8<sup>+</sup> and CD4<sup>+</sup> Melanoma-Reactive T Cells by Retroviral-Mediated Transfer of a Single T-Cell Receptor
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Functional Characterization of EBV-Encoded Nuclear Antigen 1–Specific CD4+ Helper and Regulatory T Cells Elicited by In vitro Peptide Stimulation
Kui Shin Voo; Guangyong Peng; Zhong Guo; Tihui Fu; Yanchun Li; Lori Frappier; Rong-Fu Wang
View articletitled, Functional Characterization of EBV-Encoded Nuclear Antigen 1–Specific CD4<sup>+</sup> Helper and Regulatory T Cells Elicited by <em>In vitro</em> Peptide Stimulation
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Endocrinology

Gene Expression Profile of Papillary Thyroid Cancer: Sources of Variability and Diagnostic Implications
Barbara Jarząb; Małgorzata Wiench; Krzysztof Fujarewicz; Krzysztof Simek; Michał Jarząb; Małgorzata Oczko-Wojciechowska; Jan Włoch; Agnieszka Czarniecka; Ewa Chmielik; Dariusz Lange; Agnieszka Pawlaczek; Sylwia Szpak; Elżbieta Gubała; Andrzej Świerniak
View articletitled, Gene Expression Profile of Papillary Thyroid Cancer: Sources of Variability and Diagnostic Implications
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Regulation of Endogenous Gene Expression in Human Non–Small Cell Lung Cancer Cells by Estrogen Receptor Ligands
Pamela A. Hershberger; A. Cecilia Vasquez; Beatriz Kanterewicz; Stephanie Land; Jill M. Siegfried; Mark Nichols
View articletitled, Regulation of Endogenous Gene Expression in Human Non–Small Cell Lung Cancer Cells by Estrogen Receptor Ligands
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Epidemiology and Prevention

One-Carbon Metabolism, MTHFR Polymorphisms, and Risk of Breast Cancer
Jia Chen; Marilie D. Gammon; Wendy Chan; Caroline Palomeque; James G. Wetmur; Geoffrey C. Kabat; Susan L. Teitelbaum; Julie A. Britton; Mary Beth Terry; Alfred I. Neugut; Regina M. Santella
View articletitled, One-Carbon Metabolism, <em>MTHFR</em> Polymorphisms, and Risk of Breast Cancer
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Letters to the Editor

RAS, MYC, and Sensitivity to Tumor Necrosis Factor-α–Related Apoptosis-Inducing Ligand–Induced Apoptosis
Yan Wang; Kim C. Quon; Deborah A. Knee
View articletitled, RAS, MYC, and Sensitivity to Tumor Necrosis Factor-α–Related Apoptosis-Inducing Ligand–Induced Apoptosis
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  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

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