Skip to Main Content

Advertisement

Umbrella Alt Text
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 65, Issue 19
1 October 2005
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Review Articles

The Transcription Factor Pokemon: A New Key Player in Cancer Pathogenesis
Takahiro Maeda; Robin M. Hobbs; Pier Paolo Pandolfi
View articletitled, The Transcription Factor <em>Pokemon</em>: A New Key Player in Cancer Pathogenesis
Open the PDF for in another window
A Functional Role for Hemostasis in Early Cancer Development
Carla Boccaccio; Paolo M. Comoglio
View articletitled, A Functional Role for Hemostasis in Early Cancer Development
Open the PDF for in another window

Meeting Reports

Inflammation in the Genesis and Perpetuation of Cancer: Summary and Recommendations from a National Cancer Institute–Sponsored Meeting
Richard M. Peek, Jr.; Suresh Mohla; Raymond N. DuBois
View articletitled, Inflammation in the Genesis and Perpetuation of Cancer: Summary and Recommendations from a National Cancer Institute–Sponsored Meeting
Open the PDF for in another window
Oncogenomics 2005 Meeting Report: Dissecting Cancer through Genome Research
Ellen G. Feigal; Nicholas C. Dracopoli; Jeffrey M. Trent
View articletitled, Oncogenomics 2005 Meeting Report: Dissecting Cancer through Genome Research
Open the PDF for in another window

Priority Reports

Caspase-1α Is Down-regulated in Human Ovarian Cancer Cells and the Overexpression of Caspase-1α Induces Apoptosis
Qiang Feng; Peixiang Li; Clara Salamanca; David Huntsman; Peter C.K. Leung; Nelly Auersperg
View articletitled, Caspase-1α Is Down-regulated in Human Ovarian Cancer Cells and the Overexpression of Caspase-1α Induces Apoptosis
Open the PDF for in another window
Genomewide Single Nucleotide Polymorphism Microarray Mapping in Basal Cell Carcinomas Unveils Uniparental Disomy as a Key Somatic Event
Muy-Teck Teh; Diana Blaydon; Tracy Chaplin; Nicola J. Foot; Spyros Skoulakis; Manoj Raghavan; Catherine A. Harwood; Charlotte M. Proby; Michael P. Philpott; Bryan D. Young; David P. Kelsell
View articletitled, Genomewide Single Nucleotide Polymorphism Microarray Mapping in Basal Cell Carcinomas Unveils Uniparental Disomy as a Key Somatic Event
Open the PDF for in another window
Overexpressed β-Catenin Blocks Nitric Oxide–Induced Apoptosis in Colonic Cancer Cells
Hongying Wang; Wallace K. MacNaughton
View articletitled, Overexpressed β-Catenin Blocks Nitric Oxide–Induced Apoptosis in Colonic Cancer Cells
Open the PDF for in another window
Reduction of Experimental Human Fibrosarcoma Lung Metastasis in Mice by Adenovirus-Mediated Cystatin C Overexpression in the Host
Charlotte Kopitz; Martina Anton; Bernd Gansbacher; Achim Krüger
View articletitled, Reduction of Experimental Human Fibrosarcoma Lung Metastasis in Mice by Adenovirus-Mediated Cystatin C Overexpression in the Host
Open the PDF for in another window
Fhit and CHK1 Have Opposing Effects on Homologous Recombination Repair
Baocheng Hu; Hongyan Wang; Xiang Wang; Hua-Rui Lu; Cuifen Huang; Simon N. Powell; Kay Huebner; Ya Wang
View articletitled, Fhit and CHK1 Have Opposing Effects on Homologous Recombination Repair
Open the PDF for in another window
Epimorphin Overexpression in the Mouse Mammary Gland Promotes Alveolar Hyperplasia and Mammary Adenocarcinoma
Jamie L. Bascom; Jimmie E. Fata; Yohei Hirai; Mark D. Sternlicht; Mina J. Bissell
View articletitled, Epimorphin Overexpression in the Mouse Mammary Gland Promotes Alveolar Hyperplasia and Mammary Adenocarcinoma
Open the PDF for in another window
The Threshold Level of Adenomatous Polyposis Coli Protein for Mouse Intestinal Tumorigenesis
Qin Li; Tomo-o Ishikawa; Masanobu Oshima; Makoto M. Taketo
View articletitled, The Threshold Level of Adenomatous Polyposis Coli Protein for Mouse Intestinal Tumorigenesis
Open the PDF for in another window
Activator Protein 2α Status Determines the Chemosensitivity of Cancer Cells: Implications in Cancer Chemotherapy
Narendra Wajapeyee; Chandrashekhar Ganpat Raut; Kumaravel Somasundaram
View articletitled, Activator Protein 2α Status Determines the Chemosensitivity of Cancer Cells: Implications in Cancer Chemotherapy
Open the PDF for in another window
Genetic Disruption of Cytosine DNA Methyltransferase Enzymes Induces Chromosomal Instability in Human Cancer Cells
Adam R. Karpf; Sei-ichi Matsui
View articletitled, Genetic Disruption of Cytosine DNA Methyltransferase Enzymes Induces Chromosomal Instability in Human Cancer Cells
Supplementary data
Open the PDF for in another window

Molecular Biology, Pathobiology, and Genetics

Overexpression of LAMP3/TSC403/DC-LAMP Promotes Metastasis in Uterine Cervical Cancer
Hiroyuki Kanao; Takayuki Enomoto; Toshihiro Kimura; Masami Fujita; Ryuichi Nakashima; Yutaka Ueda; Yuko Ueno; Takashi Miyatake; Tatsuo Yoshizaki; Gregory S. Buzard; Akira Tanigami; Kiyoshi Yoshino; Yuji Murata
View articletitled, Overexpression of <em>LAMP3/TSC403/DC-LAMP</em> Promotes Metastasis in Uterine Cervical Cancer
Open the PDF for in another window
The Cell Cycle Checkpoint Gene Rad9 Is a Novel Oncogene Activated by 11q13 Amplification and DNA Methylation in Breast Cancer
Chi Keung Cheng; Louis W.C. Chow; Wings T.Y. Loo; Tai Kwong Chan; Vivian Chan
View articletitled, The Cell Cycle Checkpoint Gene <em>Rad9</em> Is a Novel Oncogene Activated by 11q13 Amplification and DNA Methylation in Breast Cancer
Open the PDF for in another window
Haploinsufficiency of Atp2a2, Encoding the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 Ca2+ Pump, Predisposes Mice to Squamous Cell Tumors via a Novel Mode of Cancer Susceptibility
Vikram Prasad; Gregory P. Boivin; Marian L. Miller; Lynne H. Liu; Christopher R. Erwin; Brad W. Warner; Gary E. Shull
View articletitled, Haploinsufficiency of <em>Atp2a2</em>, Encoding the Sarco(endo)plasmic Reticulum Ca<sup>2+</sup>-ATPase Isoform 2 Ca<sup>2+</sup> Pump, Predisposes Mice to Squamous Cell Tumors via a Novel Mode of Cancer Susceptibility
Open the PDF for in another window
Contributions by MutL Homologues Mlh3 and Pms2 to DNA Mismatch Repair and Tumor Suppression in the Mouse
Peng-Chieh Chen; Sandra Dudley; Wayne Hagen; Diana Dizon; Leslie Paxton; Denise Reichow; Song-Ro Yoon; Kan Yang; Norman Arnheim; R. Michael Liskay; Steven M. Lipkin
View articletitled, Contributions by MutL Homologues <em>Mlh3</em> and <em>Pms2</em> to DNA Mismatch Repair and Tumor Suppression in the Mouse
Supplementary data
Open the PDF for in another window
Targeted Disruption of Smad4 in Mouse Epidermis Results in Failure of Hair Follicle Cycling and Formation of Skin Tumors
Leilei Yang; Chunming Mao; Yan Teng; Wenlong Li; Jishuai Zhang; Xuan Cheng; Xiaobing Li; Xinghai Han; Zhaofan Xia; Hongkui Deng; Xiao Yang
View articletitled, Targeted Disruption of Smad4 in Mouse Epidermis Results in Failure of Hair Follicle Cycling and Formation of Skin Tumors
Open the PDF for in another window
Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps and Three Novel MYC-Interacting Genes in Human Gliomas
Markus Bredel; Claudia Bredel; Dejan Juric; Griffith R. Harsh; Hannes Vogel; Lawrence D. Recht; Branimir I. Sikic
View articletitled, Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps and Three Novel MYC-Interacting Genes in Human Gliomas
Supplementary data
Open the PDF for in another window
Up-regulation of Delta-like 4 Ligand in Human Tumor Vasculature and the Role of Basal Expression in Endothelial Cell Function
Nilay S. Patel; Ji-Liang Li; Daniele Generali; Richard Poulsom; David W. Cranston; Adrian L. Harris
View articletitled, Up-regulation of Delta-like 4 Ligand in Human Tumor Vasculature and the Role of Basal Expression in Endothelial Cell Function
Open the PDF for in another window
Expression of the EWS/FLI-1 Oncogene in Murine Primary Bone-Derived Cells Results in EWS/FLI-1–Dependent, Ewing Sarcoma–Like Tumors
Yeny Castillero-Trejo; Susan Eliazer; Lilin Xiang; James A. Richardson; Robert L. Ilaria, Jr.
View articletitled, Expression of the <em>EWS/FLI-1</em> Oncogene in Murine Primary Bone-Derived Cells Results in EWS/FLI-1–Dependent, Ewing Sarcoma–Like Tumors
Open the PDF for in another window
A Novel Isoform of TUCAN Is Overexpressed in Human Cancer Tissues and Suppresses Both Caspase-8– and Caspase-9–Mediated Apoptosis
Masaaki Yamamoto; Toshihiko Torigoe; Kenjiro Kamiguchi; Yoshihiko Hirohashi; Katsuya Nakanishi; Chika Nabeta; Hiroko Asanuma; Tetsuhiro Tsuruma; Takashi Sato; Fumitake Hata; Tousei Ohmura; Koji Yamaguchi; Takehiro Kurotaki; Koichi Hirata; Noriyuki Sato
View articletitled, A Novel Isoform of TUCAN Is Overexpressed in Human Cancer Tissues and Suppresses Both Caspase-8– and Caspase-9–Mediated Apoptosis
Supplementary data
Open the PDF for in another window
Overlapping Gene Expression in Fetal Mouse Intestine Development and Human Colorectal Cancer
Michael Hu; Ramesh A. Shivdasani
View articletitled, Overlapping Gene Expression in Fetal Mouse Intestine Development and Human Colorectal Cancer
Open the PDF for in another window
Proficient Global Nucleotide Excision Repair in Human Keratinocytes but not in Fibroblasts Deficient in p53
Bridget E. Ferguson; Dennis H. Oh
View articletitled, Proficient Global Nucleotide Excision Repair in Human Keratinocytes but not in Fibroblasts Deficient in p53
Open the PDF for in another window
Destruction Box–Dependent Degradation of Aurora B Is Mediated by the Anaphase-Promoting Complex/Cyclosome and Cdh1
Scott Stewart; Guowei Fang
View articletitled, Destruction Box–Dependent Degradation of Aurora B Is Mediated by the Anaphase-Promoting Complex/Cyclosome and Cdh1
Open the PDF for in another window
Atm Heterozygosity Cooperates with Loss of Brca1 to Increase the Severity of Mammary Gland Cancer and Reduce Ductal Branching
T.J. Bowen; Hiroyuki Yakushiji; Cristina Montagna; Sonia Jain; Thomas Ried; Anthony Wynshaw-Boris
View articletitled, <em>Atm</em> Heterozygosity Cooperates with Loss of <em>Brca1</em> to Increase the Severity of Mammary Gland Cancer and Reduce Ductal Branching
Supplementary data
Open the PDF for in another window

Cell and Tumor Biology

ATM and p21 Cooperate to Suppress Aneuploidy and Subsequent Tumor Development
Kate C. Shen; Henry Heng; Yaolin Wang; Shu Lu; Guo Liu; Chu-Xia Deng; S.C. Brooks; Y. Alan Wang
View articletitled, ATM and p21 Cooperate to Suppress Aneuploidy and Subsequent Tumor Development
Open the PDF for in another window
Rexinoid-Triggered Differentiation and Tumor-Selective Apoptosis of Acute Myeloid Leukemia by Protein Kinase A–Mediated Desubordination of Retinoid X Receptor
Lucia Altucci; Aurélie Rossin; Oliver Hirsch; Angela Nebbioso; Dominique Vitoux; Emmanuelle Wilhelm; Fabien Guidez; Mariacarla De Simone; Ettore Mariano Schiavone; David Grimwade; Arthur Zelent; Hugues de Thé; Hinrich Gronemeyer
View articletitled, Rexinoid-Triggered Differentiation and Tumor-Selective Apoptosis of Acute Myeloid Leukemia by Protein Kinase A–Mediated Desubordination of Retinoid X Receptor
Open the PDF for in another window
Metabolic Mapping of MCF10A Human Breast Cells via Multiphoton Fluorescence Lifetime Imaging of the Coenzyme NADH
Damian K. Bird; Long Yan; Kristin M. Vrotsos; Kevin W. Eliceiri; Emily M. Vaughan; Patricia J. Keely; John G. White; Nirmala Ramanujam
View articletitled, Metabolic Mapping of MCF10A Human Breast Cells via Multiphoton Fluorescence Lifetime Imaging of the Coenzyme NADH
Open the PDF for in another window
P-Cadherin Promotes Cell-Cell Adhesion and Counteracts Invasion in Human Melanoma
Veerle Van Marck; Christophe Stove; Karolien Van Den Bossche; Veronique Stove; Joana Paredes; Yves Vander Haeghen; Marc Bracke
View articletitled, P-Cadherin Promotes Cell-Cell Adhesion and Counteracts Invasion in Human Melanoma
Supplementary data
Open the PDF for in another window
Tid1 Negatively Regulates the Migratory Potential of Cancer Cells by Inhibiting the Production of Interleukin-8
Sung-Woo Kim; Masaaki Hayashi; Jeng-Fan Lo; Colleen Fearns; Rong Xiang; Gwendal Lazennec; Young Yang; Jiing-Dwan Lee
View articletitled, Tid1 Negatively Regulates the Migratory Potential of Cancer Cells by Inhibiting the Production of Interleukin-8
Open the PDF for in another window
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Bodour Salhia; Frederieke Rutten; Mitsutoshi Nakada; Christian Beaudry; Michael Berens; Allison Kwan; James T. Rutka
View articletitled, Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Open the PDF for in another window
Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166/MEMD), a Novel Actor in Invasive Growth, Controls Matrix Metalloproteinase Activity
Pim C. Lunter; Jeroen W.J. van Kilsdonk; Hanneke van Beek; Ine M.H.A. Cornelissen; Mieke Bergers; Peter H.G.M. Willems; Goos N.P. van Muijen; Guido W.M. Swart
View articletitled, Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166/MEMD), a Novel Actor in Invasive Growth, Controls Matrix Metalloproteinase Activity
Open the PDF for in another window
Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Rosalyn D. Blumenthal; Hans J. Hansen; David M. Goldenberg
View articletitled, Inhibition of Adhesion, Invasion, and Metastasis by Antibodies Targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)
Open the PDF for in another window
The Bisphosphonate YM529 Inhibits Osteolytic and Osteoblastic Changes and CXCR-4–Induced Invasion in Prostate Cancer
Sotaro Miwa; Atsushi Mizokami; Evan T. Keller; Russell Taichman; Jian Zhang; Mikio Namiki
View articletitled, The Bisphosphonate YM529 Inhibits Osteolytic and Osteoblastic Changes and CXCR-4–Induced Invasion in Prostate Cancer
Open the PDF for in another window
Epstein-Barr Virus Latent Membrane Protein 1 (CAO) Up-regulates VEGF and TGFα Concomitant with Hyperlasia, with Subsequent Up-regulation of p16 and MMP9
David Stevenson; Chrystalla Charalambous; Joanna B. Wilson
View articletitled, Epstein-Barr Virus Latent Membrane Protein 1 (CAO) Up-regulates VEGF and TGFα Concomitant with Hyperlasia, with Subsequent Up-regulation of p16 and MMP9
Open the PDF for in another window
E-Cadherin Regulates the Association between β-Catenin and Actinin-4
Yasuharu Hayashida; Kazufumi Honda; Masashi Idogawa; Yoshinori Ino; Masaya Ono; Akihiko Tsuchida; Tatsuya Aoki; Setsuo Hirohashi; Tesshi Yamada
View articletitled, E-Cadherin Regulates the Association between β-Catenin and Actinin-4
Open the PDF for in another window
Increased Susceptibility of Vault Poly(ADP-Ribose) Polymerase–Deficient Mice to Carcinogen-Induced Tumorigenesis
Sujna Raval-Fernandes; Valerie A. Kickhoefer; Christina Kitchen; Leonard H. Rome
View articletitled, Increased Susceptibility of Vault Poly(ADP-Ribose) Polymerase–Deficient Mice to Carcinogen-Induced Tumorigenesis
Open the PDF for in another window
Stable RNA Interference–Mediated Suppression of Cyclophilin A Diminishes Non–Small-Cell Lung Tumor Growth In vivo
Brandon A. Howard; Ryohei Furumai; Michael J. Campa; Zahid N. Rabbani; Zeljko Vujaskovic; Xiao-Fan Wang; Edward F. Patz, Jr.
View articletitled, Stable RNA Interference–Mediated Suppression of Cyclophilin A Diminishes Non–Small-Cell Lung Tumor Growth <em>In vivo</em>
Open the PDF for in another window
Rho GTPase-Activating Protein Deleted in Liver Cancer Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma
Chun-Ming Wong; Judy Wai-Ping Yam; Yick-Pang Ching; Tai-On Yau; Thomas Ho-Yin Leung; Dong-Yan Jin; Irene Oi-Lin Ng
View articletitled, Rho GTPase-Activating Protein Deleted in Liver Cancer Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma
Supplementary data
Open the PDF for in another window
Gene Expression Changes and Signaling Events Associated with the Direct Antimelanoma Effect of IFN-γ
Jared A. Gollob; Catherine J. Sciambi; Zhiqing Huang; Holly K. Dressman
View articletitled, Gene Expression Changes and Signaling Events Associated with the Direct Antimelanoma Effect of IFN-γ
Open the PDF for in another window
Oncogenes and Angiogenesis: Down-regulation of Thrombospondin-1 in Normal Fibroblasts Exposed to Factors from Cancer Cells Harboring Mutant Ras
Wojciech Kalas; Joanne L. Yu; Chloe Milsom; Jack Rosenfeld; Robert Benezra; Paul Bornstein; Janusz Rak
View articletitled, Oncogenes and Angiogenesis: Down-regulation of Thrombospondin-1 in Normal Fibroblasts Exposed to Factors from Cancer Cells Harboring Mutant Ras
Open the PDF for in another window
Stromal Expression of Connective Tissue Growth Factor Promotes Angiogenesis and Prostate Cancer Tumorigenesis
Feng Yang; Jennifer A. Tuxhorn; Steven J. Ressler; Stephanie J. McAlhany; Truong D. Dang; David R. Rowley
View articletitled, Stromal Expression of Connective Tissue Growth Factor Promotes Angiogenesis and Prostate Cancer Tumorigenesis
Open the PDF for in another window
Breast Cancer Cells Stimulate Neutrophils to Produce Oncostatin M: Potential Implications for Tumor Progression
Marisa M. Queen; Randall E. Ryan; Ryan G. Holzer; Cynthia R. Keller-Peck; Cheryl L. Jorcyk
View articletitled, Breast Cancer Cells Stimulate Neutrophils to Produce Oncostatin M: Potential Implications for Tumor Progression
Supplementary data
Open the PDF for in another window
Atypical Protein Kinase Cι Is an Oncogene in Human Non–Small Cell Lung Cancer
Roderick P. Regala; Capella Weems; Lee Jamieson; Andras Khoor; Eric S. Edell; Christine M. Lohse; Alan P. Fields
View articletitled, Atypical Protein Kinase Cι Is an Oncogene in Human Non–Small Cell Lung Cancer
Open the PDF for in another window
Bcr-Abl Expression Levels Determine the Rate of Development of Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia
David J. Barnes; Danai Palaiologou; Eleni Panousopoulou; Beate Schultheis; Agnes S.M. Yong; Alice Wong; Laura Pattacini; John M. Goldman; Junia V. Melo
View articletitled, Bcr-Abl Expression Levels Determine the Rate of Development of Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia
Open the PDF for in another window
Topotecan-Triggered Degradation of Topoisomerase I Is p53-Dependent and Impacts Cell Survival
Maja T. Tomicic; Markus Christmann; Bernd Kaina
View articletitled, Topotecan-Triggered Degradation of Topoisomerase I Is p53-Dependent and Impacts Cell Survival
Open the PDF for in another window
Src Inhibits Adriamycin-Induced Senescence and G2 Checkpoint Arrest by Blocking the Induction of p21waf1
Arnaud Vigneron; Igor B. Roninson; Erick Gamelin; Olivier Coqueret
View articletitled, Src Inhibits Adriamycin-Induced Senescence and G<sub>2</sub> Checkpoint Arrest by Blocking the Induction of p21waf1
Open the PDF for in another window
Decreased Replication Ability of E1-Deleted Adenoviruses Correlates with Increased Brain Tumor Malignancy
Subrata Ghosh; Gregory J. Duigou
View articletitled, Decreased Replication Ability of E1-Deleted Adenoviruses Correlates with Increased Brain Tumor Malignancy
Open the PDF for in another window
Retention of Intrinsic Stem Cell Hierarchies in Carcinoma-Derived Cell Lines
Matthew Locke; Matthew Heywood; Stuart Fawell; Ian C. Mackenzie
View articletitled, Retention of Intrinsic Stem Cell Hierarchies in Carcinoma-Derived Cell Lines
Open the PDF for in another window
Effect of p53 Status and STAT1 on Chemotherapy-Induced, Fas-Mediated Apoptosis in Colorectal Cancer
Ultan McDermott; Daniel B. Longley; Leeona Galligan; Wendy Allen; Timothy Wilson; Patrick G. Johnston
View articletitled, Effect of p53 Status and STAT1 on Chemotherapy-Induced, Fas-Mediated Apoptosis in Colorectal Cancer
Open the PDF for in another window
CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer
Jens M. Teodoridis; Jacqueline Hall; Sharon Marsh; Hilary D. Kannall; Catriona Smyth; Jorge Curto; Nadeem Siddiqui; Hani Gabra; Howard L. McLeod; Gordon Strathdee; Robert Brown
View articletitled, CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer
Open the PDF for in another window
Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression
Jingrui Jiang; Heidi Greulich; Pasi A. Jänne; William R. Sellers; Matthew Meyerson; James D. Griffin
View articletitled, Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression
Open the PDF for in another window

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Effective Tumor Cell Death by σ-2 Receptor Ligand Siramesine Involves Lysosomal Leakage and Oxidative Stress
Marie Stampe Ostenfeld; Nicole Fehrenbacher; Maria Høyer-Hansen; Christian Thomsen; Thomas Farkas; Marja Jäättelä
View articletitled, Effective Tumor Cell Death by σ-2 Receptor Ligand Siramesine Involves Lysosomal Leakage and Oxidative Stress
Open the PDF for in another window
Sequence-Specific Knockdown of EWS-FLI1 by Targeted, Nonviral Delivery of Small Interfering RNA Inhibits Tumor Growth in a Murine Model of Metastatic Ewing's Sarcoma
Siwen Hu-Lieskovan; Jeremy D. Heidel; Derek W. Bartlett; Mark E. Davis; Timothy J. Triche
View articletitled, Sequence-Specific Knockdown of EWS-FLI1 by Targeted, Nonviral Delivery of Small Interfering RNA Inhibits Tumor Growth in a Murine Model of Metastatic Ewing's Sarcoma
Supplementary data
Open the PDF for in another window
Suppression of Progression and Metastasis of Established Colon Tumors in Mice by Intravenous Delivery of Short Interfering RNA Targeting KITENIN, a Metastasis-Enhancing Protein
Ji Hee Lee; Eun Song Cho; Mi-Young Kim; Young-Woo Seo; Dhong Hyo Kho; Ik Joo Chung; Hyun Kook; Nack Sung Kim; Kyu Youn Ahn; Kyung Keun Kim
View articletitled, Suppression of Progression and Metastasis of Established Colon Tumors in Mice by Intravenous Delivery of Short Interfering RNA Targeting KITENIN, a Metastasis-Enhancing Protein
Open the PDF for in another window
Down-Regulation of Vascular Endothelial Cell Growth Factor-C Expression Using Small Interfering RNA Vectors in Mammary Tumors Inhibits Tumor Lymphangiogenesis and Spontaneous Metastasis and Enhances Survival
Zhengtang Chen; Michelle L. Varney; Matthew W. Backora; Kenneth Cowan; Joyce C. Solheim; James E. Talmadge; Rakesh K. Singh
View articletitled, Down-Regulation of Vascular Endothelial Cell Growth Factor-C Expression Using Small Interfering RNA Vectors in Mammary Tumors Inhibits Tumor Lymphangiogenesis and Spontaneous Metastasis and Enhances Survival
Open the PDF for in another window
Pharmacologic Modulation of Glycogen Synthase Kinase-3β Promotes p53-Dependent Apoptosis through a Direct Bax-Mediated Mitochondrial Pathway in Colorectal Cancer Cells
Jing Tan; Li Zhuang; Hui-Sun Leong; N. Gopalakrishna Iyer; Edison T. Liu; Qiang Yu
View articletitled, Pharmacologic Modulation of Glycogen Synthase Kinase-3β Promotes p53-Dependent Apoptosis through a Direct Bax-Mediated Mitochondrial Pathway in Colorectal Cancer Cells
Open the PDF for in another window
Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function
Daniel Escuin; Erik R. Kline; Paraskevi Giannakakou
View articletitled, Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function
Open the PDF for in another window
Role of the p38 Mitogen-Activated Protein Kinase Pathway in Cytokine-Mediated Hematopoietic Suppression in Myelodysplastic Syndromes
Efstratios Katsoulidis; Yongzhong Li; Patrick Yoon; Antonella Sassano; Jessica Altman; Padma Kannan-Thulasiraman; Lakshmi Balasubramanian; Simrit Parmar; John Varga; Martin S. Tallman; Amit Verma; Leonidas C. Platanias
View articletitled, Role of the p38 Mitogen-Activated Protein Kinase Pathway in Cytokine-Mediated Hematopoietic Suppression in Myelodysplastic Syndromes
Open the PDF for in another window
The In vitro and In vivo Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases
Stuart Emanuel; Catherine A. Rugg; Robert H. Gruninger; Ronghui Lin; Angel Fuentes-Pesquera; Peter J. Connolly; Steven K. Wetter; Beth Hollister; Walter W. Kruger; Cheryl Napier; Linda Jolliffe; Steven A. Middleton
View articletitled, The <em>In vitro</em> and <em>In vivo</em> Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases
Open the PDF for in another window
Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Dehe Kong; Eun Jung Park; Andrew G. Stephen; Maura Calvani; John H. Cardellina; Anne Monks; Robert J. Fisher; Robert H. Shoemaker; Giovanni Melillo
View articletitled, Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Supplementary data
Open the PDF for in another window
Targeted Virus Replication Plus Immunotherapy Eradicates Primary and Distant Pancreatic Tumors in Nude Mice
Devanand Sarkar; Zao-zhong Su; Nicolaq Vozhilla; Eun Sook Park; Aaron Randolph; Kristoffer Valerie; Paul B. Fisher
View articletitled, Targeted Virus Replication Plus Immunotherapy Eradicates Primary and Distant Pancreatic Tumors in Nude Mice
Open the PDF for in another window
Molecular Evidence for Increased Antitumor Activity of Gemcitabine by Genistein In vitro and In vivo Using an Orthotopic Model of Pancreatic Cancer
Sanjeev Banerjee; Yuxiang Zhang; Shadan Ali; Mohammad Bhuiyan; Zhiwei Wang; Paul J. Chiao; Philip A. Philip; James Abbruzzese; Fazlul H. Sarkar
View articletitled, Molecular Evidence for Increased Antitumor Activity of Gemcitabine by Genistein <em>In vitro</em> and <em>In vivo</em> Using an Orthotopic Model of Pancreatic Cancer
Open the PDF for in another window
Endoplasmic Reticulum Stress Signal Mediators Are Targets of Selenium Action
Yue Wu; Haitao Zhang; Yan Dong; Young-Mee Park; Clement Ip
View articletitled, Endoplasmic Reticulum Stress Signal Mediators Are Targets of Selenium Action
Open the PDF for in another window

Immunology

Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes
Terence P.F. Gade; Waleed Hassen; Elmer Santos; Gertrude Gunset; Aurore Saudemont; Michael C. Gong; Renier Brentjens; Xiao-Song Zhong; Matthias Stephan; Jolanta Stefanski; Clay Lyddane; Joseph R. Osborne; Ian M. Buchanan; Simon J. Hall; Warren D. Heston; Isabelle Rivière; Steven M. Larson; Jason A. Koutcher; Michel Sadelain
View articletitled, Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes
Supplementary data
Open the PDF for in another window
Fusion Protein Vaccine by Domains of Bacterial Exotoxin Linked with a Tumor Antigen Generates Potent Immunologic Responses and Antitumor Effects
Chao-Wei Liao; Chi-An Chen; Chien-Nan Lee; Yi-Ning Su; Ming-Cheng Chang; Ming-Houg Syu; Chang-Yao Hsieh; Wen-Fang Cheng
View articletitled, Fusion Protein Vaccine by Domains of Bacterial Exotoxin Linked with a Tumor Antigen Generates Potent Immunologic Responses and Antitumor Effects
Open the PDF for in another window
Src Homology 2–Containing Inositol 5′-Phosphatase 1 Negatively Regulates IFN-γ Production by Natural Killer Cells Stimulated with Antibody-Coated Tumor Cells and Interleukin-12
Robin Parihar; Rossana Trotta; Julie M. Roda; Amy K. Ferketich; Susheela Tridandapani; Michael A. Caligiuri; William E. Carson, III
View articletitled, Src Homology 2–Containing Inositol 5′-Phosphatase 1 Negatively Regulates IFN-γ Production by Natural Killer Cells Stimulated with Antibody-Coated Tumor Cells and Interleukin-12
Open the PDF for in another window

Corrections

Gene Expression Profiles of Oligodendrogliomas
View articletitled, Gene Expression Profiles of Oligodendrogliomas
Open the PDF for in another window
PPAR and Carcinogenesis
View articletitled, PPAR and Carcinogenesis
Open the PDF for in another window
Toll-Like Receptors on Tumor Cells
View articletitled, Toll-Like Receptors on Tumor Cells
Open the PDF for in another window

Advertisement

Email alerts

eTOC Alert
Close Modal
Breaking
Vaccine Falls Short against HPV+ Cancers
Gene Therapy Causes Cancer in Some Children
GSK to Settle Zantac Lawsuits for $2.2 Billion
View more recent articles
Latest News
Protein Innovators Win Chemistry Nobel
Nobel-Winning AI Advances Are Transforming Cancer Research
COVID-19 Vaccines Linked to Improved Survival in ICI-Treated Cancers
View more recent articles
Research Watch
Membrane Protein Degradation via Transferrin Receptor Targeted Chimeras
Epigenetic Modification of Centromeric RNA Supports Genomic Stability
Patient Response to Immunotherapy Is Dictated by Five Latent Factors
View more recent articles

NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale within the United States of Bavencio® (avelumab), a pharmaceutical owned by Merck. If any resulting funds are received, they would not be used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

AACR Journals

 

 

  • Copyright © 2023 by the American Association for Cancer Research.
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept