Skip to Main Content

Advertisement

American Association for Cancer Research Logo
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 64, Issue 22
15 November 2004
Cancer Research Cover Image for Volume 64, Issue 22
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Review

Endogenous Inhibitors of Nuclear Factor-κB, An Opportunity for Cancer Control
Fei Chen
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Advances in Brief

Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α
Xiuwu Zhang; Takashi Kon; He Wang; Fang Li; Qian Huang; Zahid N. Rabbani; John P. Kirkpatrick; Zeljko Vujaskovic; Mark W. Dewhirst; Chuan-Yuan Li
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Significant Contribution of Germline BRCA2 Rearrangements in Male Breast Cancer Families
Isabelle Tournier; Brigitte Bressac-de Paillerets; Hagay Sobol; Dominique Stoppa-Lyonnet; Rosette Lidereau; Michel Barrois; Sylvie Mazoyer; Florence Coulet; Agnès Hardouin; Agnès Chompret; Alain Lortholary; Pierre Chappuis; Violaine Bourdon; Valérie Bonadona; Christine Maugard; Brigitte Gilbert; Catherine Nogues; Thierry Frébourg; Mario Tosi
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Inhibition of Extracellular-signal Regulated Kinases 1/2 Is Required for Apoptosis of Human Colon Cancer Cells In vitro by Sulindac Metabolites
Pamela L. Rice; K. Scott Beard; Linda J. Driggers; Dennis J. Ahnen
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Cul4A Physically Associates with MDM2 and Participates in the Proteolysis of p53
Alo Nag; Srilata Bagchi; Pradip Raychaudhuri
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Frequent Aberrant Methylation of the CDH4 Gene Promoter in Human Colorectal and Gastric Cancer
Elena Miotto; Silvia Sabbioni; Angelo Veronese; George A. Calin; Sergio Gullini; Alberto Liboni; Laura Gramantieri; Luigi Bolondi; Eros Ferrazzi; Roberta Gafà; Giovanni Lanza; Massimo Negrini
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window

Molecular Biology, Pathobiology, and Genetics

Overexpression of Glycine-Extended Gastrin Inhibits Parietal Cell Loss and Atrophy in the Mouse Stomach
Guanglin Cui; Theodore J. Koh; Duan Chen; Chun-Mei Zhao; Shigeo Takaishi; Graham J. Dockray; Andrea Varro; Arlin B. Rogers; James G. Fox; Timothy C. Wang
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
Weiguang Wang; James Cassidy; Vincent O’Brien; Kevin M. Ryan; Elaina Collie-Duguid
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Characterization of a Carcinogenesis Rat Model of Ovarian Preneoplasia and Neoplasia
Sherri L. Stewart; Troy D. Querec; Alexander R. Ochman; Briana N. Gruver; Rudi Bao; James S. Babb; Thang S. Wong; Theodoros Koutroukides; Aaron D. Pinnola; Andres Klein-Szanto; Thomas C. Hamilton; Christos Patriotis
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Loss of Estrogen Receptor Signaling Triggers Epigenetic Silencing of Downstream Targets in Breast Cancer
Yu-Wei Leu; Pearlly S. Yan; Meiyun Fan; Victor X. Jin; Joseph C. Liu; Edward M. Curran; Wade V. Welshons; Susan H. Wei; Ramana V. Davuluri; Christoph Plass; Kenneth P. Nephew; Tim H-M. Huang
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Regulation of Protein Catabolism by Muscle-Specific and Cytokine-Inducible Ubiquitin Ligase E3α-II during Cancer Cachexia
Keith S. Kwak; Xiaolan Zhou; Vered Solomon; Vickie E. Baracos; James Davis; Anthony W. Bannon; William J. Boyle; David L. Lacey; H.Q. Han
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Comparison of the Effect of Mutant and Wild-Type p53 on Global Gene Expression
Thomas J. O’Farrell; Paritosh Ghosh; Nobuaki Dobashi; Carl Y. Sasaki; Dan L. Longo
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Nuclear Hormone Receptor NR4A2 Is Involved in Cell Transformation and Apoptosis
Ning Ke; Gisela Claassen; De-Hua Yu; Aaron Albers; Wufang Fan; Philip Tan; Mirta Grifman; Xiuyuan Hu; Kristin DeFife; Vivian Nguy; Bernd Meyhack; Arndt Brachat; Flossie Wong-Staal; Qi-Xiang Li
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Cell and Tumor Biology

DNA Microarrays Reveal Relationship of Ewing Family Tumors to Both Endothelial and Fetal Neural Crest-Derived Cells and Define Novel Targets
Martin S. Staege; Christoph Hutter; Ingo Neumann; Sabine Foja; Uwe E. Hattenhorst; Gesine Hansen; Danny Afar; Stefan E. G. Burdach
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Inhibition of Melanoma Growth and Metastasis by ATF2-Derived Peptides
Anindita Bhoumik; Lisa Gangi; Ze’ev Ronai
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Ionizing Radiation Induces Frequent Translocations with Delayed Replication and Condensation
Kevin S. Breger; Leslie Smith; Mitchell S. Turker; Mathew J. Thayer
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Limited Capability of Regional Lymph Nodes to Eradicate Metastatic Cancer Cells
Hiroshi Nagata; Tsunenori Arai; Yusuke Soejima; Hidekazu Suzuki; Hiromasa Ishii; Toshifumi Hibi
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Tumor-Associated Endothelial Cells with Cytogenetic Abnormalities
Kyoko Hida; Yasuhiro Hida; Dhara N. Amin; Alan F. Flint; Dipak Panigrahy; Cynthia C. Morton; Michael Klagsbrun
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Physical and Functional Interactions between the Wwox Tumor Suppressor Protein and the AP-2γ Transcription Factor
Rami I. Aqeilan; Alexey Palamarchuk; Ronald J. Weigel; Juan J. Herrero; Yuri Pekarsky; Carlo M. Croce
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
BRAK/CXCL14 Is a Potent Inhibitor of Angiogenesis and a Chemotactic Factor for Immature Dendritic Cells
Thomas D. Shellenberger; Mary Wang; Manu Gujrati; Arumugam Jayakumar; Robert M. Strieter; Marie D. Burdick; Constantin G. Ioannides; Clayton L. Efferson; Adel K. El-Naggar; Dianna Roberts; Gary L. Clayman; Mitchell J. Frederick
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Role of Synaptojanin 2 in Glioma Cell Migration and Invasion
Ya-yu Chuang; Nhan L. Tran; Nicole Rusk; Mitsutoshi Nakada; Michael E. Berens; Marc Symons
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Bone Morphogenetic Protein (BMP)-6 Signaling and BMP Antagonist Noggin in Prostate Cancer
Dominik R. Haudenschild; Sabrina M. Palmer; Timothy A. Moseley; Zongbing You; A. Hari Reddi
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Host Acid Sphingomyelinase Regulates Microvascular Function Not Tumor Immunity
Monica Garcia-Barros; Daniel Lacorazza; Howard Petrie; Adriana Haimovitz-Friedman; Carlos Cardon-Cardo; Stephen Nimer; Zvi Fuks; Richard Kolesnick
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
SHP-2-Dependent Mitogen-Activated Protein Kinase Activation Regulates EGFRvIII but not Wild-Type Epidermal Growth Factor Receptor Phosphorylation and Glioblastoma Cell Survival
Yi Zhan; Donald M. O’Rourke
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
The Nuclear Receptor Coactivator AIB1 Mediates Insulin-like Growth Factor I-induced Phenotypic Changes in Human Breast Cancer Cells
Annabell Oh; Heinz-Joachim List; Ronald Reiter; Aparna Mani; Ying Zhang; Edmund Gehan; Anton Wellstein; Anna T. Riegel
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
P-Cadherin Is Up-Regulated by the Antiestrogen ICI 182,780 and Promotes Invasion of Human Breast Cancer Cells
Joana Paredes; Christophe Stove; Veronique Stove; Fernanda Milanezi; Veerle Van Marck; Lara Derycke; Marc Mareel; Marc Bracke; Fernando Schmitt
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window
Transactivation of the EGR1 Gene Contributes to Mutant p53 Gain of Function
Lilach Weisz; Amir Zalcenstein; Perry Stambolsky; Yehudit Cohen; Naomi Goldfinger; Moshe Oren; Varda Rotter
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
24-Hour Oscillation of Mouse Methionine Aminopeptidase2, a Regulator of Tumor Progression, Is Regulated by Clock Gene Proteins
Hiroo Nakagawa; Satoru Koyanagi; Takako Takiguchi; Yukako Kuramoto; Shinji Soeda; Hiroshi Shimeno; Shun Higuchi; Shigehiro Ohdo
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Nuclear βII-Tubulin Associates with the Activated Notch Receptor to Modulate Notch Signaling
Tien-Shun Yeh; Rong-Hong Hsieh; Shing-Chuan Shen; Shwu-Huey Wang; Min-Jen Tseng; Chwen-Ming Shih; Jing-Jer Lin
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Lymphocyte Transformation by Pim-2 Is Dependent on Nuclear Factor-κB Activation
Peter S. Hammerman; Casey J. Fox; Ryan M. Cinalli; Anne Xu; John D. Wagner; Tullia Lindsten; Craig B. Thompson
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma
Melinda S. Merchant; Xuezhong Yang; Fraia Melchionda; Maria Romero; Ruth Klein; Carol J. Thiele; Maria Tsokos; H. Udo Kontny; Crystal L. Mackall
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
STAT1: A Modulator of Chemotherapy-induced Apoptosis
Michelle Thomas; Clodagh E. Finnegan; Katherine M.-A. Rogers; James W. Purcell; Anne Trimble; Patrick G. Johnston; Marion P. Boland
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Evidence that TRPM8 Is an Androgen-Dependent Ca2+ Channel Required for the Survival of Prostate Cancer Cells
Lei Zhang; Gregory John Barritt
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and Ellipticine N2-Oxide
Marie Stiborová; Jan Sejbal; Lucie Bořek-Dohalská; Dagmar Aimová; Jitka Poljaková; Kristina Forsterová; Martina Rupertová; Jiří Wiesner; Jiří Hudeček; Manfred Wiessler; Eva Frei
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Ectopic Expression of Interferon Regulatory Factor-1 Promotes Human Breast Cancer Cell Death and Results in Reduced Expression of Survivin
Eva Pizzoferrato; Ye Liu; Andrea Gambotto; Michaele J. Armstrong; Michael T. Stang; William E. Gooding; Sean M. Alber; Stuart H. Shand; Simon C. Watkins; Walter J. Storkus; John H. Yim
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Cyclin B1 Is a Critical Target of RhoB in the Cell Suicide Program Triggered by Farnesyl Transferase Inhibition
Uma Kamasani; Minzhou Huang; James B. DuHadaway; Edward V. Prochownik; P. Scott Donover; George C. Prendergast
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Phosphatidylinositol 3′-Kinase Activation Leads to Multidrug Resistance Protein-1 Expression and Subsequent Chemoresistance in Advanced Prostate Cancer Cells
John T. Lee, Jr.; Linda S. Steelman; James A. McCubrey
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Synergistic Interaction between Sphingomyelin and Gemcitabine Potentiates Ceramide-Mediated Apoptosis in Pancreatic Cancer
David E. Modrak; Thomas M. Cardillo; Guy A. Newsome; David M. Goldenberg; David V. Gold
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Immunology

Anti-CD137 Monoclonal Antibody Administration Augments the Antitumor Efficacy of Dendritic Cell-Based Vaccines
Fumito Ito; Qiao Li; Andrew B. Shreiner; Ryuji Okuyama; Maria N. Jure-Kunkel; Seagal Teitz-Tennenbaum; Alfred E. Chang
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4
Federica Marchesi; Paolo Monti; Biagio Eugenio Leone; Alessandro Zerbi; Annunciata Vecchi; Lorenzo Piemonti; Alberto Mantovani; Paola Allavena
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Immunological Prevention of a Multigene Cancer Syndrome
Stefania Croci; Giordano Nicoletti; Lorena Landuzzi; Carla De Giovanni; Annalisa Astolfi; Chiara Marini; Emma Di Carlo; Piero Musiani; Guido Forni; Patrizia Nanni; Pier-Luigi Lollini
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Highly Successful Therapeutic Vaccinations Combining Dendritic Cells and Tumor Cells Secreting Granulocyte Macrophage Colony-stimulating Factor
Gregory Driessens; Malika Hamdane; Vincent Cool; Thierry Velu; Catherine Bruyns
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
C-Type Lectin-Like Molecule-1: A Novel Myeloid Cell Surface Marker Associated with Acute Myeloid Leukemia
Alexander B. H. Bakker; Sonja van den Oudenrijn; Arjen Q. Bakker; Nicole Feller; Marja van Meijer; Judith A. Bia; Mandy A. C. Jongeneelen; Therese J. Visser; Nora Bijl; Cecilia A. W. Geuijen; Wilfred E. Marissen; Katarina Radosevic; Mark Throsby; Gerrit Jan Schuurhuis; Gert J. Ossenkoppele; John de Kruif; Jaap Goudsmit; Ada M. Kruisbeek
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Bone Marrow Is a Reservoir for CD4+CD25+ Regulatory T Cells that Traffic through CXCL12/CXCR4 Signals
Linhua Zou; Brian Barnett; Hana Safah; Vincent F. LaRussa; Melina Evdemon-Hogan; Peter Mottram; Shuang Wei; Odile David; Tyler J. Curiel; Weiping Zou
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Clinical Research

Local Administration of Granulocyte/Macrophage Colony-stimulating Factor Increases the Number and Activation State of Dendritic Cells in the Sentinel Lymph Node of Early-Stage Melanoma
Ronald J. C. L. M. Vuylsteke; Barbara G. Molenkamp; Hester A. Gietema; Paul A. M. van Leeuwen; Pepijn G. J. T. B. Wijnands; Wim Vos; Paul J. van Diest; Rik J. Scheper; Sybren Meijer; Tanja D. de Gruijl
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Epidemiology and Prevention

CYP3A4, CYP3A5, and CYP3A43 Genotypes and Haplotypes in the Etiology and Severity of Prostate Cancer
Charnita Zeigler-Johnson; Tara Friebel; Amy H. Walker; Yiting Wang; Elaine Spangler; Saarene Panossian; Margerie Patacsil; Richard Aplenc; Alan J. Wein; S. Bruce Malkowicz; Timothy R. Rebbeck
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Reduced Immunoglobulin E and Allergy among Adults with Glioma Compared with Controls
Joseph L. Wiemels; John K. Wiencke; Joseph Patoka; Michelle Moghadassi; Terri Chew; Alex McMillan; Rei Miike; Geoffrey Barger; Margaret Wrensch
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Supplementary data
Open the PDF for in another window

Meeting Reports

Sixteenth Annual Pezcoller Symposium: Stem Cells and Epigenesis in Cancer
Enrico Mihich; Rudolf Jaenisch
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
In vivo Models for Experimental Therapeutics Relevant to Human Cancer
Miriam S. Gitler; Edward A. Sausville; Melinda Hollingshead; Robert Shoemaker
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Letters to the Editor

Kallikrein 4 Is a Secreted Protein
James P. Simmer; John D. Bartlett
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Corrections

Corrections
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window
Corrections
View articletitled, SCM.SharedControls.Infrastructure.TitleDisplayModel?.Text
Open the PDF for in another window

Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

Advertisement

Email alerts

eTOC Alert
Close Modal
Latest News
Q&A: Daniel Drucker on GLP-1 Drugs and Their Potential for Cancer
Protein Map Illuminates Hidden Drivers of Childhood Cancer
Cancer Throughlines: Almost 20 Years On, HPV Vaccine Still Surpasses Expectations
View more recent articles
Breaking
Q&A: Douglas Hanahan on the Hallmarks of Cancer and Future Avenues in Cancer Research
Former NCI Director to Lead Ohio Cancer Center
Penpulimab OK’d for Nasopharyngeal Carcinoma
View more recent articles
Research Watch
Dietary Fat Promotes Triple-Negative Breast Cancer through FABP5–mTOR
ROS Sensing Regulates Mitochondrial Translation and Chemotherapy Response
Ligand Engagement Induces LAG3 Checkpoint Activity through Ubiquitination
View more recent articles

NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck.  None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

AACR Journals

 

 

  • Copyright © 2025 by the American Association for Cancer Research.
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept