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Issues

Volume 63, Issue 24
15 December 2003
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Perspectives in Cancer Research

Harnessing Apoptosis for Improved Anticancer Gene Therapy
David J. Waxman; Pamela S. Schwartz
View articletitled, Harnessing Apoptosis for Improved Anticancer Gene Therapy
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Advances in Brief

Optic Nerve Glioma in Mice Requires Astrocyte Nf1 Gene Inactivation and Nf1 Brain Heterozygosity
M. Livia Bajenaru; M. Rosario Hernandez; Arie Perry; Yuan Zhu; Luis F. Parada; Joel R. Garbow; David H. Gutmann
View articletitled, Optic Nerve Glioma in Mice Requires Astrocyte <strong><em>Nf1</em></strong> Gene Inactivation and <strong><em>Nf1</em></strong> Brain Heterozygosity
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Hyper-Recombination and Genetic Instability in BLM-Deficient Epithelial Cells
Giovanni Traverso; Chetan Bettegowda; Jürgen Kraus; Michael R. Speicher; Kenneth W. Kinzler; Bert Vogelstein; Christoph Lengauer
View articletitled, Hyper-Recombination and Genetic Instability in BLM-Deficient Epithelial Cells
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Use of Complete Coverage Array Comparative Genomic Hybridization to Define Copy Number Alterations on Chromosome 3p in Oral Squamous Cell Carcinomas
Cathie Garnis; Corisande Baldwin; Lewei Zhang; Miriam P. Rosin; Wan L. Lam
View articletitled, Use of Complete Coverage Array Comparative Genomic Hybridization to Define Copy Number Alterations on Chromosome 3p in Oral Squamous Cell Carcinomas
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53BP1 and NFBD1/MDC1-Nbs1 Function in Parallel Interacting Pathways Activating Ataxia-Telangiectasia Mutated (ATM) in Response to DNA Damage
Tamara A. Mochan; Monica Venere; Richard A. DiTullio, Jr.; Thanos D. Halazonetis
View articletitled, 53BP1 and NFBD1/MDC1-Nbs1 Function in Parallel Interacting Pathways Activating Ataxia-Telangiectasia Mutated (ATM) in Response to DNA Damage
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Activating Transcription Factor 4 Increases the Cisplatin Resistance of Human Cancer Cell Lines
Mizuho Tanabe; Hiroto Izumi; Tomoko Ise; Shun Higuchi; Takao Yamori; Kosei Yasumoto; Kimitoshi Kohno
View articletitled, Activating Transcription Factor 4 Increases the Cisplatin Resistance of Human Cancer Cell Lines
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Evaluation of Fanconi Anemia Genes in Familial Breast Cancer Predisposition
Sheila Seal; Rita Barfoot; Hiran Jayatilake; Paula Smith; Anthony Renwick; Linda Bascombe; Lesley McGuffog; D. Gareth Evans; Diana Eccles; The Breast Cancer Susceptibility Collaboration (UK); Douglas F. Easton; Michael R. Stratton; Nazneen Rahman
View articletitled, Evaluation of Fanconi Anemia Genes in Familial Breast Cancer Predisposition
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Additive Interaction of Oxaliplatin and 17-Allylamino-17-demethoxygeldanamycin in Colon Cancer Cell Lines Results from Inhibition of Nuclear Factor κB Signaling
Tatiana V. Rakitina; Irina A. Vasilevskaya; Peter J. O’Dwyer
View articletitled, Additive Interaction of Oxaliplatin and 17-Allylamino-17-demethoxygeldanamycin in Colon Cancer Cell Lines Results from Inhibition of Nuclear Factor κB Signaling
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Molecular Biology, Pathobiology, and Genetics

Epigenetic Inactivation of CHFR and Sensitivity to Microtubule Inhibitors in Gastric Cancer
Ayumi Satoh; Minoru Toyota; Fumio Itoh; Yasushi Sasaki; Hiromu Suzuki; Kazuhiro Ogi; Takefumi Kikuchi; Hiroaki Mita; Toshiharu Yamashita; Takashi Kojima; Masanobu Kusano; Masahiro Fujita; Masao Hosokawa; Takao Endo; Takashi Tokino; Kohzoh Imai
View articletitled, Epigenetic Inactivation of CHFR and Sensitivity to Microtubule Inhibitors in Gastric Cancer
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Highly Expressed Genes in Pancreatic Ductal Adenocarcinomas: A Comprehensive Characterization and Comparison of the Transcription Profiles Obtained from Three Major Technologies
Christine A. Iacobuzio-Donahue; Raheela Ashfaq; Anirban Maitra; N. Volkan Adsay; Grace L. Shen-Ong; Karin Berg; Michael A. Hollingsworth; John L. Cameron; Charles J. Yeo; Scott E. Kern; Michael Goggins; Ralph H. Hruban
View articletitled, Highly Expressed Genes in Pancreatic Ductal Adenocarcinomas<span class="subtitle-colon">: </span><span class="subtitle">A Comprehensive Characterization and Comparison of the Transcription Profiles Obtained from Three Major Technologies</span>
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Methylation of Cytochrome P4501A1 Promoter in the Lung Is Associated with Tobacco Smoking
Sisko Anttila; Jukka Hakkola; Päivi Tuominen; Eivor Elovaara; Kirsti Husgafvel-Pursiainen; Antti Karjalainen; Ari Hirvonen; Tuula Nurminen
View articletitled, Methylation of Cytochrome P4501A1 Promoter in the Lung Is Associated with Tobacco Smoking
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An Opposing View on WWOX Protein Function as a Tumor Suppressor
Akira Watanabe; Yoshitaka Hippo; Hirokazu Taniguchi; Hiroko Iwanari; Masakazu Yashiro; Kosei Hirakawa; Tatsuhiko Kodama; Hiroyuki Aburatani
View articletitled, An Opposing View on WWOX Protein Function as a Tumor Suppressor
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Karyotypic Complexity of the NCI-60 Drug-Screening Panel
Anna V. Roschke; Giovanni Tonon; Kristen S. Gehlhaus; Nicolas McTyre; Kimberly J. Bussey; Samir Lababidi; Dominic A. Scudiero; John N. Weinstein; Ilan R. Kirsch
View articletitled, Karyotypic Complexity of the NCI-60 Drug-Screening Panel
Supplementary data
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Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression
Euan A. Stronach; Grant C. Sellar; Cherie Blenkiron; Genevieve J. Rabiasz; Karen J. Taylor; Eric P. Miller; Charles E. Massie; Awatif Al-Nafussi; John F. Smyth; David J. Porteous; Hani Gabra
View articletitled, Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression
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BCL2 Accelerates Inflammation-induced BALB/c Plasmacytomas and Promotes Novel Tumors with Coexisting T(12;15) and T(6;15) Translocations
Santiago Silva; Alexander L. Kovalchuk; Joong Su Kim; George Klein; Siegfried Janz
View articletitled, <strong><em>BCL2</em></strong> Accelerates Inflammation-induced BALB/c Plasmacytomas and Promotes Novel Tumors with Coexisting T(12;15) and T(6;15) Translocations
Supplementary data
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Switching Mechanisms of Cell Death in mdm2- and mdm4-null Mice by Deletion of p53 Downstream Targets
Arturo Chavez-Reyes; John M. Parant; Lisa L. Amelse; Roberto Montes de Oca Luna; Stanley J. Korsmeyer; Guillermina Lozano
View articletitled, Switching Mechanisms of Cell Death in <strong><em>mdm2</em></strong>- and <strong><em>mdm4</em></strong>-null Mice by Deletion of p53 Downstream Targets
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Inactivation of Wild-Type p53 Protein Function by Reactive Oxygen and Nitrogen Species in Malignant Glioma Cells
Charles S. Cobbs; Thomas R. Whisenhunt; Duane R. Wesemann; Lualhati E. Harkins; Erwin G. Van Meir; Minu Samanta
View articletitled, Inactivation of Wild-Type p53 Protein Function by Reactive Oxygen and Nitrogen Species in Malignant Glioma Cells
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Hepatocyte Growth Factor Activator Inhibitor 2/Placental Bikunin (HAI-2/PB) Gene Is Frequently Hypermethylated in Human Hepatocellular Carcinoma
Kenichi Fukai; Osamu Yokosuka; Tetsuhiro Chiba; Yuichi Hirasawa; Motohisa Tada; Fumio Imazeki; Hiroaki Kataoka; Hiromitsu Saisho
View articletitled, <strong><em>Hepatocyte Growth Factor Activator Inhibitor 2/Placental Bikunin</em></strong> (<strong><em>HAI-2/PB</em></strong>) Gene Is Frequently Hypermethylated in Human Hepatocellular Carcinoma
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Epigenetic Regulation of Coxsackie and Adenovirus Receptor (CAR) Gene Promoter in Urogenital Cancer Cells
Rey-Chen Pong; Yun-Ju Lai; Hong Chen; Takasugu Okegawa; Eugene Frenkel; Arthur Sagalowsky; Jer-Tsong Hsieh
View articletitled, Epigenetic Regulation of <strong><em>Coxsackie and Adenovirus Receptor</em></strong> (<strong><em>CAR</em></strong>) Gene Promoter in Urogenital Cancer Cells
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Notch1 Can Contribute to Viral-Induced Transformation of Primary Human Keratinocytes
Stéphanie Lathion; Janina Schaper; Peter Beard; Kenneth Raj
View articletitled, Notch1 Can Contribute to Viral-Induced Transformation of Primary Human Keratinocytes
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Promoter Hypermethylation of Tumor Suppressor Genes in Urine from Kidney Cancer Patients
Cristina Battagli; Robert G. Uzzo; Essel Dulaimi; Inmaculada Ibanez de Caceres; Rachel Krassenstein; Tahseen Al-Saleem; Richard E. Greenberg; Paul Cairns
View articletitled, Promoter Hypermethylation of Tumor Suppressor Genes in Urine from Kidney Cancer Patients
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Phorbol Ester Stimulates the Nonhypoxic Induction of a Novel Hypoxia-Inducible Factor 1α Isoform: Implications for Tumor Promotion
Yang-Sook Chun; Kyoung-Hwa Lee; Eunjoo Choi; Soo-Young Bae; Eun-Jin Yeo; L. Eric Huang; Myung-Suk Kim; Jong-Wan Park
View articletitled, Phorbol Ester Stimulates the Nonhypoxic Induction of a Novel Hypoxia-Inducible Factor 1α Isoform<span class="subtitle-colon">: </span><span class="subtitle">Implications for Tumor Promotion</span>
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Enhancement of the Mutagenicity of Benzo(a)pyrene Diol Epoxide by a Nonmutagenic Dose of Ultraviolet A Radiation
Ahmad Besaratinia; Gerd P. Pfeifer
View articletitled, Enhancement of the Mutagenicity of Benzo(<strong><em>a</em></strong>)pyrene Diol Epoxide by a Nonmutagenic Dose of Ultraviolet A Radiation
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ATMHaplotypes and Cellular Response to DNA Damage: Association with Breast Cancer Risk and Clinical Radiosensitivity
Sandra Angèle; Pascale Romestaing; Norman Moullan; Michèle Vuillaume; Brigitte Chapot; Marlin Friesen; Wim Jongmans; David G. Cox; Paola Pisani; Jean-Pierre Gérard; Janet Hall
View articletitled, <strong><em>ATM</em></strong>Haplotypes and Cellular Response to DNA Damage<span class="subtitle-colon">: </span><span class="subtitle">Association with Breast Cancer Risk and Clinical Radiosensitivity</span>
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TIP49 Regulates β-Catenin-Mediated Neoplastic Transformation and T-Cell Factor Target Gene Induction via Effects on Chromatin Remodeling
Ying Feng; Nana Lee; Eric R. Fearon
View articletitled, TIP49 Regulates β-Catenin-Mediated Neoplastic Transformation and T-Cell Factor Target Gene Induction via Effects on Chromatin Remodeling
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Cell and Tumor Biology

An Endogenous Retrovirus Derived from Human Melanoma Cells
Thomas Muster; Andrea Waltenberger; Andreas Grassauer; Sonja Hirschl; Peri Caucig; Ingrid Romirer; Dagmar Födinger; Heide Seppele; Oliver Schanab; Christine Magin-Lachmann; Roswitha Löwer; Burkhard Jansen; Hubert Pehamberger; Klaus Wolff
View articletitled, An Endogenous Retrovirus Derived from Human Melanoma Cells
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Tamoxifen Inhibits Secretion of Vascular Endothelial Growth Factor in Breast Cancer in Vivo
Stina Garvin; Charlotta Dabrosin
View articletitled, Tamoxifen Inhibits Secretion of Vascular Endothelial Growth Factor in Breast Cancer <strong><em>in Vivo</em></strong>
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High Heparanase Activity in Multiple Myeloma Is Associated with Elevated Microvessel Density
Thomas Kelly; Hua-Quan Miao; Yang Yang; Elizabeth Navarro; Paul Kussie; Yan Huang; Veronica MacLeod; Jonathan Casciano; Lija Joseph; Fenghuang Zhan; Maurizio Zangari; Bart Barlogie; John Shaughnessy; Ralph D. Sanderson
View articletitled, High Heparanase Activity in Multiple Myeloma Is Associated with Elevated Microvessel Density
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Activation of Signal Transducer and Activator of Transcription 5 is Required for Progression of Autochthonous Prostate Cancer: Evidence from the Transgenic Adenocarcinoma of the Mouse Prostate System
Alexander V. Kazansky; David M. Spencer; Norman M. Greenberg
View articletitled, Activation of Signal Transducer and Activator of Transcription 5 is Required for Progression of Autochthonous Prostate Cancer<span class="subtitle-colon">: </span><span class="subtitle">Evidence from the Transgenic Adenocarcinoma of the Mouse Prostate System</span>
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TIP30 Deficiency Increases Susceptibility to Tumorigenesis
Mitsuhiro Ito; Chao Jiang; Kristy Krumm; Xia Zhang; Jill Pecha; Jian Zhao; Yajun Guo; Robert G. Roeder; Hua Xiao
View articletitled, TIP30 Deficiency Increases Susceptibility to Tumorigenesis
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IG20, a MADD Splice Variant, Increases Cell Susceptibility to γ-Irradiation and Induces Soluble Mediators That Suppress Tumor Cell Growth
Elena Efimova; Osvaldo Martinez; Anna Lokshin; Takayasu Arima; Bellur S. Prabhakar
View articletitled, IG20, a MADD Splice Variant, Increases Cell Susceptibility to γ-Irradiation and Induces Soluble Mediators That Suppress Tumor Cell Growth
Supplementary data
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Expression of Prolyl-Hydroxylase-1 (PHD1/EGLN2) Suppresses Hypoxia Inducible Factor-1α Activation and Inhibits Tumor Growth
Neta Erez; Michael Milyavsky; Raya Eilam; Igor Shats; Naomi Goldfinger; Varda Rotter
View articletitled, Expression of Prolyl-Hydroxylase-1 (PHD1/EGLN2) Suppresses Hypoxia Inducible Factor-1α Activation and Inhibits Tumor Growth
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Cooperation between Ectopic FGFR1 and Depression of FGFR2 in Induction of Prostatic Intraepithelial Neoplasia in the Mouse Prostate
Chengliu Jin; Kerstin McKeehan; Wei Guo; Scot Jauma; Michael M. Ittmann; Barbara Foster; Norman M. Greenberg; Wallace L. McKeehan; Fen Wang
View articletitled, Cooperation between Ectopic FGFR1 and Depression of FGFR2 in Induction of Prostatic Intraepithelial Neoplasia in the Mouse Prostate
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Gene Expression Profiling-Based Prediction of Response of Colon Carcinoma Cells to 5-Fluorouracil and Camptothecin
John M. Mariadason; Diego Arango; Qiuhu Shi; Andrew J. Wilson; Georgia A. Corner; Courtney Nicholas; Maria J. Aranes; Martin Lesser; Edward L. Schwartz; Leonard H. Augenlicht
View articletitled, Gene Expression Profiling-Based Prediction of Response of Colon Carcinoma Cells to 5-Fluorouracil and Camptothecin
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Cyclophosphamide Treatment Modifies Tumor Oxygenation and Glycolytic Rates of RIF-1 Tumors: 13C Magnetic Resonance Spectroscopy, Eppendorf Electrode, and Redox Scanning
Harish Poptani; Navin Bansal; Walter T. Jenkins; Dana Blessington; Anthony Mancuso; David S. Nelson; Michael Feldman; Edward J. Delikatny; Britton Chance; Jerry D. Glickson
View articletitled, Cyclophosphamide Treatment Modifies Tumor Oxygenation and Glycolytic Rates of RIF-1 Tumors<span class="subtitle-colon">: </span><span class="subtitle"><sup>13</sup>C Magnetic Resonance Spectroscopy, Eppendorf Electrode, and Redox Scanning</span>
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Regulation of Heparanase Gene Expression by Estrogen in Breast Cancer
Michael Elkin; Irit Cohen; Eyal Zcharia; Adam Orgel; Zehava Guatta-Rangini; Tamar Peretz; Israel Vlodavsky; Hynda K. Kleinman
View articletitled, Regulation of Heparanase Gene Expression by Estrogen in Breast Cancer
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Migration-Stimulating Factor: A Genetically Truncated Onco-Fetal Fibronectin Isoform Expressed by Carcinoma and Tumor-Associated Stromal Cells
Seth L. Schor; Ian R. Ellis; Sarah J. Jones; Robin Baillie; Kanjula Seneviratne; Julia Clausen; Katsumi Motegi; Borek Vojtesek; Katerina Kankova; Elizabeth Furrie; Mark J. Sales; Ana M. Schor; Richard A. Kay
View articletitled, Migration-Stimulating Factor<span class="subtitle-colon">: </span><span class="subtitle">A Genetically Truncated Onco-Fetal Fibronectin Isoform Expressed by Carcinoma and Tumor-Associated Stromal Cells</span>
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Activation of p21-Activated Kinase 1-Nuclear Factor κB Signaling by Kaposi’s Sarcoma-Associated Herpes Virus G Protein-Coupled Receptor during Cellular Transformation
Disha Dadke; Benjamin H. Fryer; Erica A. Golemis; Jeffrey Field
View articletitled, Activation of p21-Activated Kinase 1-Nuclear Factor κB Signaling by Kaposi’s Sarcoma-Associated Herpes Virus G Protein-Coupled Receptor during Cellular Transformation
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Keratinocyte Growth Factor Produced by Gastric Fibroblasts Specifically Stimulates Proliferation of Cancer Cells from Scirrhous Gastric Carcinoma
Kazunori Nakazawa; Masakazu Yashiro; Kosei Hirakawa
View articletitled, Keratinocyte Growth Factor Produced by Gastric Fibroblasts Specifically Stimulates Proliferation of Cancer Cells from Scirrhous Gastric Carcinoma
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MKP-1-Induced Dephosphorylation of Extracellular Signal-Regulated Kinase Is Essential for Triggering Nitric Oxide-Induced Apoptosis in Human Breast Cancer Cell Lines: Implications in Breast Cancer
Shehla Pervin; Rajan Singh; William A. Freije; Gautam Chaudhuri
View articletitled, MKP-1-Induced Dephosphorylation of Extracellular Signal-Regulated Kinase Is Essential for Triggering Nitric Oxide-Induced Apoptosis in Human Breast Cancer Cell Lines<span class="subtitle-colon">: </span><span class="subtitle">Implications in Breast Cancer</span>
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Patterns of Chromosomal Imbalances Defines Subgroups of Breast Cancer with Distinct Clinical Features and Prognosis. A Study of 305 Tumors by Comparative Genomic Hybridization
Karin Rennstam; Minna Ahlstedt-Soini; Bo Baldetorp; Pär-Ola Bendahl; Åke Borg; Ritva Karhu; Minna Tanner; Mika Tirkkonen; Jorma Isola
View articletitled, Patterns of Chromosomal Imbalances Defines Subgroups of Breast Cancer with Distinct Clinical Features and Prognosis. A Study of 305 Tumors by Comparative Genomic Hybridization
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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Cephalostatin 1 Selectively Triggers the Release of Smac/DIABLO and Subsequent Apoptosis That Is Characterized by an Increased Density of the Mitochondrial Matrix
Verena M. Dirsch; Irina M. Müller; Sören T. Eichhorst; George R. Pettit; Yoshiaki Kamano; Masuo Inoue; Jun-Ping Xu; Yoshitatsu Ichihara; Gerhard Wanner; Angelika M. Vollmar
View articletitled, Cephalostatin 1 Selectively Triggers the Release of Smac/DIABLO and Subsequent Apoptosis That Is Characterized by an Increased Density of the Mitochondrial Matrix
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Cellular and Genetic Characterization of Human Adult Bone Marrow-Derived Neural Stem-Like Cells: A Potential Antiglioma Cellular Vector
Jeongwu Lee; Abdel G. Elkahloun; Steven A. Messina; Nicolay Ferrari; Dan Xi; Carolyn L. Smith; Ronald Cooper, Jr.; Paul S. Albert; Howard A. Fine
View articletitled, Cellular and Genetic Characterization of Human Adult Bone Marrow-Derived Neural Stem-Like Cells<span class="subtitle-colon">: </span><span class="subtitle">A Potential Antiglioma Cellular Vector</span>
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Combined Therapy with Direct and Indirect Angiogenesis Inhibition Results in Enhanced Antiangiogenic and Antitumor Effects
Amir Abdollahi; Kenneth E. Lipson; Axel Sckell; Heike Zieher; Frank Klenke; Daniel Poerschke; Alexandra Roth; Xiaohong Han; Martin Krix; Marc Bischof; Philip Hahnfeldt; Hermann-Josef Grone; Juergen Debus; Lynn Hlatky; Peter E. Huber
View articletitled, Combined Therapy with Direct and Indirect Angiogenesis Inhibition Results in Enhanced Antiangiogenic and Antitumor Effects
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Adenosine 5′-triphosphate-sensitive Potassium Channel-mediated Blood-Brain Tumor Barrier Permeability Increase in a Rat Brain Tumor Model
Nagendra S. Ningaraj; Mamatha K. Rao; Keith L. Black
View articletitled, Adenosine 5′-triphosphate-sensitive Potassium Channel-mediated Blood-Brain Tumor Barrier Permeability Increase in a Rat Brain Tumor Model
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A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth in Vivo
Douglas Burtrum; Zhenping Zhu; Dan Lu; Donna Marie Anderson; Marie Prewett; Daniel S. Pereira; Rajiv Bassi; Rashed Abdullah; Andrea T. Hooper; Henry Koo; Xenia Jimenez; Danielle Johnson; Robin Apblett; Paul Kussie; Peter Bohlen; Larry Witte; Daniel J. Hicklin; Dale L. Ludwig
View articletitled, A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth <strong><em>in Vivo</em></strong>
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Geranylgeranyltransferase I Inhibitor GGTI-2154 Induces Breast Carcinoma Apoptosis and Tumor Regression in H-Ras Transgenic Mice
Jiazhi Sun; Junko Ohkanda; Domenico Coppola; Hang Yin; Mohit Kothare; Brian Busciglio; Andrew D. Hamilton; Saïd M. Sebti
View articletitled, Geranylgeranyltransferase I Inhibitor GGTI-2154 Induces Breast Carcinoma Apoptosis and Tumor Regression in H-Ras Transgenic Mice
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Combinatorial Efficacy Achieved Through Two-Point Blockade within a Signaling Pathway—A Chemical Genetic Approach
Qi-Wen Fan; Kimberly Musa Specht; Chao Zhang; Dmitriy D. Goldenberg; Kevan M. Shokat; William A. Weiss
View articletitled, Combinatorial Efficacy Achieved Through Two-Point Blockade within a Signaling Pathway—A Chemical Genetic Approach
Supplementary data
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Identification of Genes Expressed in Malignant Cells That Promote Invasion
Jennifer Walter-Yohrling; Xiaohong Cao; Michele Callahan; William Weber; Sharon Morgenbesser; Stephen L. Madden; Clarence Wang; Beverly A. Teicher
View articletitled, Identification of Genes Expressed in Malignant Cells That Promote Invasion
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Induction of PIG3 and NOXA through Acetylation of p53 at 320 and 373 Lysine Residues as a Mechanism for Apoptotic Cell Death by Histone Deacetylase Inhibitors
Takeshi Terui; Ken Murakami; Rishu Takimoto; Minoru Takahashi; Koichi Takada; Tsuzuku Murakami; Shinya Minami; Takuya Matsunaga; Tetsuji Takayama; Junji Kato; Yoshiro Niitsu
View articletitled, Induction of <strong><em>PIG3</em></strong> and <strong><em>NOXA</em></strong> through Acetylation of p53 at 320 and 373 Lysine Residues as a Mechanism for Apoptotic Cell Death by Histone Deacetylase Inhibitors
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Butyrates, as a Single Drug, Induce Histone Acetylation and Granulocytic Maturation: Possible Selectivity on Core Binding Factor-Acute Myeloid Leukemia Blasts
Antonella Gozzini; Elisabetta Rovida; Persio Dello Sbarba; Sara Galimbert; Valeria Santini
View articletitled, Butyrates, as a Single Drug, Induce Histone Acetylation and Granulocytic Maturation<span class="subtitle-colon">: </span><span class="subtitle">Possible Selectivity on Core Binding Factor-Acute Myeloid Leukemia Blasts</span>
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Intratumoral Immunization with Tumor RNA-Pulsed Dendritic Cells Confers Antitumor Immunity in a C57BL/6 Pancreatic Murine Tumor Model
Tanja Schmidt; Carsten Ziske; Angela Märten; Stefan Endres; Klaus Tiemann; Volker Schmitz; Marcus Gorschlüter; Christof Schneider; Tilman Sauerbruch; Ingo G. H. Schmidt-Wolf
View articletitled, Intratumoral Immunization with Tumor RNA-Pulsed Dendritic Cells Confers Antitumor Immunity in a C57BL/6 Pancreatic Murine Tumor Model
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Repression of Vascular Endothelial Growth Factor A in Glioblastoma Cells Using Engineered Zinc Finger Transcription Factors
Andrew W. Snowden; Lei Zhang; Fyodor Urnov; Carolyn Dent; Yann Jouvenot; Xiaohong Zhong; Edward J. Rebar; Andrew C. Jamieson; H. Steven Zhang; Siyuan Tan; Casey C. Case; Carl O. Pabo; Alan P. Wolffe; Philip D. Gregory
View articletitled, Repression of Vascular Endothelial Growth Factor A in Glioblastoma Cells Using Engineered Zinc Finger Transcription Factors
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Novel Cisplatin-Incorporated Polymeric Micelles Can Eradicate Solid Tumors in Mice
Nobuhiro Nishiyama; Souichiro Okazaki; Horacio Cabral; Masaki Miyamoto; Yukio Kato; Yuichi Sugiyama; Kazuto Nishio; Yasuhiro Matsumura; Kazunori Kataoka
View articletitled, Novel Cisplatin-Incorporated Polymeric Micelles Can Eradicate Solid Tumors in Mice
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Geldanamycin and 17-Allylamino-17-demethoxygeldanamycin Potentiate the in Vitro and in Vivo Radiation Response of Cervical Tumor Cells via the Heat Shock Protein 90-Mediated Intracellular Signaling and Cytotoxicity
Kheem S. Bisht; C. Matthew Bradbury; David Mattson; Aradhana Kaushal; Anastasia Sowers; Stephanie Markovina; Karen L. Ortiz; Leah K. Sieck; Jennifer S. Isaacs; Martin W. Brechbiel; James B. Mitchell; Leonard M. Neckers; David Gius
View articletitled, Geldanamycin and 17-Allylamino-17-demethoxygeldanamycin Potentiate the <strong><em>in Vitro</em></strong> and <strong><em>in Vivo</em></strong> Radiation Response of Cervical Tumor Cells via the Heat Shock Protein 90-Mediated Intracellular Signaling and Cytotoxicity
Supplementary data
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Immunology

MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas
Manuel A. Friese; Michael Platten; Stefan Z. Lutz; Ulrike Naumann; Steffen Aulwurm; Felix Bischof; Hans-Jörg Bühring; Johannes Dichgans; Hans-Georg Rammensee; Alexander Steinle; Michael Weller
View articletitled, MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas
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Extra-Lymphatic Solid Tumor Growth Is Not Immunologically Ignored and Results in Early Induction of Antigen-Specific T-Cell Anergy: Dominant Role of Cross-Tolerance to Tumor Antigens
Alex Cuenca; Fengdong Cheng; Hongwei Wang; Jason Brayer; Pedro Horna; Lingping Gu; Harold Bien; Ivan M. Borrello; Hyam I. Levitsky; Eduardo M. Sotomayor
View articletitled, Extra-Lymphatic Solid Tumor Growth Is Not Immunologically Ignored and Results in Early Induction of Antigen-Specific T-Cell Anergy<span class="subtitle-colon">: </span><span class="subtitle">Dominant Role of Cross-Tolerance to Tumor Antigens</span>
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In Vivo Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells
Gang Wang; Mary Tschoi; Rosanne Spolski; Yanyan Lou; Katsutoshi Ozaki; Chiguang Feng; Grace Kim; Warren J. Leonard; Patrick Hwu
View articletitled, <strong><em>In Vivo</em></strong> Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells
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β-Glucan Functions as an Adjuvant for Monoclonal Antibody Immunotherapy by Recruiting Tumoricidal Granulocytes as Killer Cells
Feng Hong; Richard D. Hansen; Jun Yan; Daniel J. Allendorf; Jarek T. Baran; Gary R. Ostroff; Gordon D. Ross
View articletitled, β-Glucan Functions as an Adjuvant for Monoclonal Antibody Immunotherapy by Recruiting Tumoricidal Granulocytes as Killer Cells
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Clinical Research

Human Kallikrein 14: A New Potential Biomarker for Ovarian and Breast Cancer
Carla A. Borgoño; Linda Grass; Antoninus Soosaipillai; George M. Yousef; Constantina D. Petraki; David H. C. Howarth; Stefano Fracchioli; Dionyssios Katsaros; Eleftherios P. Diamandis
View articletitled, Human Kallikrein 14<span class="subtitle-colon">: </span><span class="subtitle">A New Potential Biomarker for Ovarian and Breast Cancer</span>
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Identification of Prognostic Markers in Bone Sarcomas Using Proton-Decoupled Phosphorus Magnetic Resonance Spectroscopy
Kristen L. Zakian; Amita Shukla-Dave; Paul Meyers; Richard Gorlick; John Healey; Howard T. Thaler; Andrew G. Huvos; David M. Panicek; Jason A. Koutcher
View articletitled, Identification of Prognostic Markers in Bone Sarcomas Using Proton-Decoupled Phosphorus Magnetic Resonance Spectroscopy
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Dysregulated Expression of COOH-Terminally Truncated Stat5 and Loss of IL2-Inducible Stat5-Dependent Gene Expression in Sezary Syndrome
Tracey J. Mitchell; Sean J. Whittaker; Susan John
View articletitled, Dysregulated Expression of COOH-Terminally Truncated Stat5 and Loss of IL2-Inducible Stat5-Dependent Gene Expression in Sezary Syndrome
Supplementary data
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Letter to the Editor

Correspondence re: S. A. W. Fuquaet al., Estrogen Receptor β Protein in Human Breast Cancer: Correlation with Clinical Tumor Parameters. Cancer Res.,63: 2434–2439, 2003.
Valerie Speirs
View articletitled, Correspondence re: S. A. W. Fuqua<strong><em>et al</em></strong>., Estrogen Receptor β Protein in Human Breast Cancer: Correlation with Clinical Tumor Parameters. Cancer Res.,<strong><em>63:</em></strong> 2434–2439, 2003.
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Acknowledgement to Reviewers

Acknowledgment to Reviewers
View articletitled, Acknowledgment to Reviewers
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  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

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