Skip to Main Content

Advertisement

Umbrella Alt Text
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 63, Issue 22
15 November 2003
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Reviews

The Days and Nights of Cancer Cells
Laurence Canaple; Tomoko Kakizawa; Vincent Laudet
View articletitled, The Days and Nights of Cancer Cells
Open the PDF for in another window
Mouse Models to Study the Interaction of Risk Factors for Human Liver Cancer
Stewart Sell
View articletitled, Mouse Models to Study the Interaction of Risk Factors for Human Liver Cancer
Open the PDF for in another window

Advances in Brief

Tea Polyphenol (−)-Epigallocatechin-3-Gallate Inhibits DNA Methyltransferase and Reactivates Methylation-Silenced Genes in Cancer Cell Lines
Ming Zhu Fang; Yimin Wang; Ni Ai; Zhe Hou; Yi Sun; Hong Lu; William Welsh; Chung S. Yang
View articletitled, Tea Polyphenol (−)-Epigallocatechin-3-Gallate Inhibits DNA Methyltransferase and Reactivates Methylation-Silenced Genes in Cancer Cell Lines
Open the PDF for in another window
Novel Magnetic Resonance Imaging Contrasts for Monitoring Response to Gene Therapy in Rat Glioma
Olli H. J. Gröhn; Piia K. Valonen; Kimmo K. Lehtimäki; Tuula H. Väisänen; Mikko I. Kettunen; Seppo Ylä-Herttuala; Risto A. Kauppinen; Michael Garwood
View articletitled, Novel Magnetic Resonance Imaging Contrasts for Monitoring Response to Gene Therapy in Rat Glioma
Open the PDF for in another window
Regulation of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase Expression by Amphiregulin in Transformed Human Breast Epithelial Cells
Suzanne Menashi; Maria Serova; Lin Ma; Stephane Vignot; Samia Mourah; Fabien Calvo
View articletitled, Regulation of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase Expression by Amphiregulin in Transformed Human Breast Epithelial Cells
Open the PDF for in another window
Pretreatment with 8-Methoxypsoralen, a Potent Human CYP2A6 Inhibitor, Strongly Inhibits Lung Tumorigenesis Induced by 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Female A/J Mice
Hijiri Takeuchi; Kousuke Saoo; Masanao Yokohira; Mico Ikeda; Hajime Maeta; Masafumi Miyazaki; Hiroshi Yamazaki; Tetsuya Kamataki; Katsumi Imaida
View articletitled, Pretreatment with 8-Methoxypsoralen, a Potent Human CYP2A6 Inhibitor, Strongly Inhibits Lung Tumorigenesis Induced by 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Female A/J Mice
Open the PDF for in another window
Treatment with the Tumor Necrosis Factor-α-Inducing Drug 5,6-Dimethylxanthenone-4-Acetic Acid Enhances the Antitumor Activity of the Photodynamic Therapy of RIF-1 Mouse Tumors
David A. Bellnier; Sandra O. Gollnick; Susan H. Camacho; William R. Greco; Richard T. Cheney
View articletitled, Treatment with the Tumor Necrosis Factor-α-Inducing Drug 5,6-Dimethylxanthenone-4-Acetic Acid Enhances the Antitumor Activity of the Photodynamic Therapy of RIF-1 Mouse Tumors
Open the PDF for in another window
Cytoplasmic HuR Expression Correlates with Poor Outcome and with Cyclooxygenase 2 Expression in Serous Ovarian Carcinoma
Tiina-Liisa Erkinheimo; Heini Lassus; Anna Sivula; Sibani Sengupta; Henry Furneaux; Timothy Hla; Caj Haglund; Ralf Butzow; Ari Ristimäki
View articletitled, Cytoplasmic HuR Expression Correlates with Poor Outcome and with Cyclooxygenase 2 Expression in Serous Ovarian Carcinoma
Open the PDF for in another window
Carcinogenesis in MYH-Associated Polyposis Follows a Distinct Genetic Pathway
Lara Lipton; Sarah E. Halford; Victoria Johnson; Marco R. Novelli; Angela Jones; Carole Cummings; Ella Barclay; Oliver Sieber; Amir Sadat; Marie-Luise Bisgaard; Shirley V. Hodgson; Lauri A. Aaltonen; Huw J. W. Thomas; Ian P. M. Tomlinson
View articletitled, Carcinogenesis in MYH-Associated Polyposis Follows a Distinct Genetic Pathway
Open the PDF for in another window
The Contribution of Genetic and Epigenetic Mechanisms to Gene Silencing in Oligodendrogliomas
Chibo Hong; Andrew W. Bollen; Joseph F. Costello
View articletitled, The Contribution of Genetic and Epigenetic Mechanisms to Gene Silencing in Oligodendrogliomas
Supplementary data
Open the PDF for in another window
Simian Virus 40 Sequences in Malignant Lymphomas in Japan
Shin-ichi Nakatsuka; Angen Liu; Zhiming Dong; Shintaro Nomura; Tetsuya Takakuwa; Hajime Miyazato; Katsuyuki Aozasa; Osaka Lymphoma Study Group
View articletitled, Simian Virus 40 Sequences in Malignant Lymphomas in Japan
Open the PDF for in another window
In Vivo Monitoring of Capecitabine Metabolism in Human Liver by 19Fluorine Magnetic Resonance Spectroscopy at 1.5 and 3 Tesla Field Strength
Hanneke W. M. van Laarhoven; Dennis W. J. Klomp; Yvonne J. L. Kamm; Cornelis J. A. Punt; Arend Heerschap
View articletitled, <strong><em>In Vivo</em></strong> Monitoring of Capecitabine Metabolism in Human Liver by <sup>19</sup>Fluorine Magnetic Resonance Spectroscopy at 1.5 and 3 Tesla Field Strength
Open the PDF for in another window
Growth Inhibition of Human Colon Cancer Cells by Nitric Oxide (NO)-Donating Aspirin Is Associated with Cyclooxygenase-2 Induction and β-Catenin/T-Cell Factor Signaling, Nuclear Factor-κB, and NO Synthase 2 Inhibition: Implications for Chemoprevention
Jennie L. Williams; Niharika Nath; Jie Chen; Thomas R. Hundley; Jianjun Gao; Levy Kopelovich; Khosrow Kashfi; Basil Rigas
View articletitled, Growth Inhibition of Human Colon Cancer Cells by Nitric Oxide (NO)-Donating Aspirin Is Associated with Cyclooxygenase-2 Induction and β-Catenin/T-Cell Factor Signaling, Nuclear Factor-κB, and NO Synthase 2 Inhibition<span class="subtitle-colon">: </span><span class="subtitle">Implications for Chemoprevention</span>
Supplementary data
Open the PDF for in another window
Inactivation of a Histone Methyltransferase by Mutations in Human Cancers
Keun-Cheol Kim; Liqing Geng; Shi Huang
View articletitled, Inactivation of a Histone Methyltransferase by Mutations in Human Cancers
Open the PDF for in another window
Joint Effect of Estrogen Receptor β Sequence Variants and Endogenous Estrogen Exposure on Breast Cancer Risk in Chinese Women
S. Lilly Zheng; Wei Zheng; Bao-li Chang; Xiao-Ou Shu; Qiuyin Cai; Herbert Yu; Qi Dai; Jianfeng Xu; Yu-Tang Gao
View articletitled, Joint Effect of Estrogen Receptor β Sequence Variants and Endogenous Estrogen Exposure on Breast Cancer Risk in Chinese Women
Open the PDF for in another window
Enhancement of Bik Antitumor Effect by Bik Mutants
Yan M. Li; Yong Wen; Binhua P. Zhou; Hsu-Ping Kuo; Qingqing Ding; Mien-Chie Hung
View articletitled, Enhancement of <strong><em>Bik</em></strong> Antitumor Effect by <strong><em>Bik</em></strong> Mutants
Open the PDF for in another window
Oxygenation Gain Factor: A Novel Parameter Characterizing the Association between Hemoglobin Level and the Oxygenation Status of Breast Cancers
Peter Vaupel; Arnulf Mayer; Susanne Briest; Michael Höckel
View articletitled, Oxygenation Gain Factor<span class="subtitle-colon">: </span><span class="subtitle">A Novel Parameter Characterizing the Association between Hemoglobin Level and the Oxygenation Status of Breast Cancers</span>
Open the PDF for in another window
p300 in Prostate Cancer Proliferation and Progression
Jose D. Debes; Thomas J. Sebo; Christine M. Lohse; Linda M. Murphy; De Anna L. Haugen; Donald J. Tindall
View articletitled, p300 in Prostate Cancer Proliferation and Progression
Open the PDF for in another window
DNA Methylation in Serum of Breast Cancer Patients: An Independent Prognostic Marker
Hannes M. Müller; Andreas Widschwendter; Heidi Fiegl; Lennart Ivarsson; Georg Goebel; Elisabeth Perkmann; Christian Marth; Martin Widschwendter
View articletitled, DNA Methylation in Serum of Breast Cancer Patients<span class="subtitle-colon">: </span><span class="subtitle">An Independent Prognostic Marker</span>
Supplementary data
Open the PDF for in another window

Molecular Biology, Pathobiology, and Genetics

Genetic and Epigenetic Alterations of DLC-1 Gene in Hepatocellular Carcinoma
Chun-Ming Wong; Joyce Man-Fong Lee; Yick-Pang Ching; Dong-Yan Jin; Irene Oi-lin Ng
View articletitled, Genetic and Epigenetic Alterations of <strong><em>DLC-1</em></strong> Gene in Hepatocellular Carcinoma
Open the PDF for in another window
Mutation Spectrum of the 9q34 Tuberous Sclerosis Gene TSC1 in Transitional Cell Carcinoma of the Bladder
Margaret A. Knowles; Tomonori Habuchi; Wendy Kennedy; Darren Cuthbert-Heavens
View articletitled, Mutation Spectrum of the 9q34 Tuberous Sclerosis Gene <strong><em>TSC1</em></strong> in Transitional Cell Carcinoma of the Bladder
Open the PDF for in another window
High-Resolution Deletion Mapping of 15q13.2-q21.1 in Transitional Cell Carcinoma of the Bladder
Rachael Natrajan; Jari Louhelainen; Sarah Williams; Jonathan Laye; Margaret A. Knowles
View articletitled, High-Resolution Deletion Mapping of 15q13.2-q21.1 in Transitional Cell Carcinoma of the Bladder
Open the PDF for in another window
Growth Factor-Independent Activation of Protein Kinase B Contributes to the Inherent Resistance of Vascular Endothelium to Radiation-Induced Apoptotic Response
Jiahuai Tan; Dennis E. Hallahan
View articletitled, Growth Factor-Independent Activation of Protein Kinase B Contributes to the Inherent Resistance of Vascular Endothelium to Radiation-Induced Apoptotic Response
Open the PDF for in another window
Loss of Protein Phosphatase 2A Expression Correlates with Phosphorylation of DP-1 and Reversal of Dysplasia through Differentiation in a Conditional Mouse Model of Cancer Progression
Maddalena T. Tilli; Shawnté L. Hudgins; M. Silvina Frech; Ewa D. Halama; Jean-Pierre Renou; Priscilla A. Furth
View articletitled, Loss of Protein Phosphatase 2A Expression Correlates with Phosphorylation of DP-1 and Reversal of Dysplasia through Differentiation in a Conditional Mouse Model of Cancer Progression
Open the PDF for in another window
Stem Cell Factor Receptor (c-KIT) Codon 816 Mutations Predict Development of Bilateral Testicular Germ-Cell Tumors
Leendert H. J. Looijenga; Hubert de Leeuw; Monique van Oorschot; Ruud J. H. L. M. van Gurp; Hans Stoop; Ad J. M. Gillis; Carlos A. de Gouveia Brazao; Rob F. A. Weber; Wim J. Kirkels; Thamar van Dijk; Marieke von Lindern; Peter Valk; Geczy Lajos; Edit Olah; Jahn M. Nesland; Sophie D. Fosså; J. Wolter Oosterhuis
View articletitled, Stem Cell Factor Receptor (c-<strong><em>KIT</em></strong>) Codon 816 Mutations Predict Development of Bilateral Testicular Germ-Cell Tumors
Open the PDF for in another window
Small Interfering RNA-Mediated Reduction in Heterogeneous Nuclear Ribonucleoparticule A1/A2 Proteins Induces Apoptosis in Human Cancer Cells but not in Normal Mortal Cell Lines
Caroline Patry; Louise Bouchard; Pascale Labrecque; Daniel Gendron; Bruno Lemieux; Johanne Toutant; Elvy Lapointe; Raymund Wellinger; Benoit Chabot
View articletitled, Small Interfering RNA-Mediated Reduction in Heterogeneous Nuclear Ribonucleoparticule A1/A2 Proteins Induces Apoptosis in Human Cancer Cells but not in Normal Mortal Cell Lines
Open the PDF for in another window
Inhibitor of Nuclear Factor κB Kinase Deficiency Enhances Oxidative Stress and Prolongs c-Jun NH2-Terminal Kinase Activation Induced by Arsenic
Fei Chen; Vince Castranova; Zhiwei Li; Michael Karin; Xianglin Shi
View articletitled, Inhibitor of Nuclear Factor κB Kinase Deficiency Enhances Oxidative Stress and Prolongs c-Jun NH<sub>2</sub>-Terminal Kinase Activation Induced by Arsenic
Open the PDF for in another window
Death-Associated Protein Kinase Promoter Hypermethylation in Normal Human Lymphocytes
Ashok N. Reddy; Wei W. Jiang; Michael Kim; Nicole Benoit; Rodney Taylor; John Clinger; David Sidransky; Joseph A. Califano
View articletitled, Death-Associated Protein Kinase Promoter Hypermethylation in Normal Human Lymphocytes
Open the PDF for in another window
Increased Formation and Persistence of 1,N6-Ethenoadenine in DNA Is Not Associated with Higher Susceptibility to Carcinogenesis in Alkylpurine- DNA-N-Glycosylase Knockout Mice Treated with Vinyl Carbamate
Alain Barbin; Rong Wang; Peter J. O’Connor; Rhoderick H. Elder
View articletitled, Increased Formation and Persistence of 1,<strong><em>N</em></strong><sup>6</sup>-Ethenoadenine in DNA Is Not Associated with Higher Susceptibility to Carcinogenesis in Alkylpurine- DNA-<strong><em>N</em></strong>-Glycosylase Knockout Mice Treated with Vinyl Carbamate
Open the PDF for in another window
Evidence of Alterations in Base Excision Repair of Oxidative DNA Damage during Spontaneous Hepatocarcinogenesis in Long Evans Cinnamon Rats
Sujata Choudhury; Ronghe Zhang; Krystyna Frenkel; Toshihiko Kawamori; Fung-Lung Chung; Rabindra Roy
View articletitled, Evidence of Alterations in Base Excision Repair of Oxidative DNA Damage during Spontaneous Hepatocarcinogenesis in Long Evans Cinnamon Rats
Open the PDF for in another window

Cell and Tumor Biology

Insulin-like Growth Factor 1 Receptor Enhances Invasion and Induces Resistance to Apoptosis of Colon Cancer Cells through the Akt/Bcl-xL Pathway
Madhavi Sekharam; Haiyan Zhao; Mei Sun; Quan Fang; Qingbo Zhang; Zengqiang Yuan; Han C. Dan; David Boulware; Jin Q. Cheng; Domenico Coppola
View articletitled, Insulin-like Growth Factor 1 Receptor Enhances Invasion and Induces Resistance to Apoptosis of Colon Cancer Cells through the Akt/Bcl-x<sub>L</sub> Pathway
Open the PDF for in another window
Restoration of Insulin-Like Growth Factor Binding Protein-Related Protein 1 Has a Tumor-Suppressive Activity through Induction of Apoptosis in Human Prostate Cancer
Kazuaki Mutaguchi; Hiroaki Yasumoto; Kouji Mita; Akio Matsubara; Hiroaki Shiina; Mikio Igawa; Rajvir Dahiya; Tsuguru Usui
View articletitled, Restoration of Insulin-Like Growth Factor Binding Protein-Related Protein 1 Has a Tumor-Suppressive Activity through Induction of Apoptosis in Human Prostate Cancer
Open the PDF for in another window
Suppression of Survivin Expression Inhibits in Vivo Tumorigenicity and Angiogenesis in Gastric Cancer
Shui Ping Tu; Xiao Hua Jiang; Marie C. M. Lin; Jian Tao Cui; Yi Yang; Ching Tung Lum; Bing Zou; Yan Bo Zhu; Shi Hu Jiang; Wai Man Wong; Annie On-On Chan; Man Fung Yuen; Shiu Kum Lam; Hsiang Fu Kung; Benjamin Chun-Yu Wong
View articletitled, Suppression of Survivin Expression Inhibits <strong><em>in Vivo</em></strong> Tumorigenicity and Angiogenesis in Gastric Cancer
Open the PDF for in another window
Heparanase Affects Adhesive and Tumorigenic Potential of Human Glioma Cells
Anna Zetser; Yulia Bashenko; Hua-Quan Miao; Israel Vlodavsky; Neta Ilan
View articletitled, Heparanase Affects Adhesive and Tumorigenic Potential of Human Glioma Cells
Open the PDF for in another window
Neuroblastoma-Derived Sulfhydryl Oxidase, a New Member of the Sulfhydryl Oxidase/Quiescin6 Family, Regulates Sensitization to Interferon γ-Induced Cell Death in Human Neuroblastoma Cells
Isabel Wittke; Ruprecht Wiedemeyer; Andrea Pillmann; Larissa Savelyeva; Frank Westermann; Manfred Schwab
View articletitled, Neuroblastoma-Derived Sulfhydryl Oxidase, a New Member of the <strong><em>Sulfhydryl Oxidase/Quiescin6</em></strong> Family, Regulates Sensitization to Interferon γ-Induced Cell Death in Human Neuroblastoma Cells
Open the PDF for in another window
Reduced Hepatocyte Proliferation is the Basis of Retarded Liver Tumor Progression and Liver Regeneration in Mice Lacking N-Acetylglucosaminyltransferase III
Xiaoping Yang; Jian Tang; Charles E. Rogler; Pamela Stanley
View articletitled, Reduced Hepatocyte Proliferation is the Basis of Retarded Liver Tumor Progression and Liver Regeneration in Mice Lacking <strong><em>N</em></strong>-Acetylglucosaminyltransferase III
Supplementary data
Open the PDF for in another window
Smad7 but not Smad6 Cooperates with Oncogenic ras to Cause Malignant Conversion in a Mouse Model for Squamous Cell Carcinoma
Xin Liu; Jennifer Lee; Margaret Cooley; Ervind Bhogte; Stephan Hartley; Adam Glick
View articletitled, Smad7 but not Smad6 Cooperates with Oncogenic <strong><em>ras</em></strong> to Cause Malignant Conversion in a Mouse Model for Squamous Cell Carcinoma
Open the PDF for in another window
Aberrant Expression and Localization of Decorin in Human Oral Dysplasia and Squamous Cell Carcinoma
Abhijit G. Banerjee; Indraneel Bhattacharyya; William M. Lydiatt; Jamboor K. Vishwanatha
View articletitled, Aberrant Expression and Localization of Decorin in Human Oral Dysplasia and Squamous Cell Carcinoma
Open the PDF for in another window
The Heat Shock Protein 90 Inhibitor Geldanamycin and the ErbB Inhibitor ZD1839 Promote Rapid PP1 Phosphatase-Dependent Inactivation of AKT in ErbB2 Overexpressing Breast Cancer Cells
Wanping Xu; Xitong Yuan; Yun Jin Jung; Yongping Yang; Andrea Basso; Neal Rosen; Eun Joo Chung; Jane Trepel; Len Neckers
View articletitled, The Heat Shock Protein 90 Inhibitor Geldanamycin and the ErbB Inhibitor ZD1839 Promote Rapid PP1 Phosphatase-Dependent Inactivation of AKT in ErbB2 Overexpressing Breast Cancer Cells
Open the PDF for in another window
Determination of Clonality of Metastasis by Cell-Specific Color-Coded Fluorescent-Protein Imaging
Norio Yamamoto; Meng Yang; Ping Jiang; Mingxu Xu; Hiroyuki Tsuchiya; Katsuro Tomita; A. R. Moossa; Robert M. Hoffman
View articletitled, Determination of Clonality of Metastasis by Cell-Specific Color-Coded Fluorescent-Protein Imaging
Open the PDF for in another window
SB-431542 and Gleevec Inhibit Transforming Growth Factor-β-Induced Proliferation of Human Osteosarcoma Cells
Shigeo Matsuyama; Manabu Iwadate; Miki Kondo; Masao Saitoh; Aki Hanyu; Kiyoshi Shimizu; Hiroyuki Aburatani; Hiromu K. Mishima; Takeshi Imamura; Kohei Miyazono; Keiji Miyazawa
View articletitled, SB-431542 and Gleevec Inhibit Transforming Growth Factor-β-Induced Proliferation of Human Osteosarcoma Cells
Open the PDF for in another window
Genetic Signatures of Differentiation Induced by 1α,25-Dihydroxyvitamin D3 in Human Colon Cancer Cells
Héctor G. Pálmer; Marta Sánchez-Carbayo; Paloma Ordóñez-Morán; María Jesús Larriba; Carlos Cordón-Cardó; Alberto Muñoz
View articletitled, Genetic Signatures of Differentiation Induced by 1α,25-Dihydroxyvitamin D<sub>3</sub> in Human Colon Cancer Cells
Open the PDF for in another window
Epidermal Growth Factor Receptor Autocrine Signaling in RIE-1 Cells Transformed by the Ras Oncogene Enhances Radiation Resistance
Theresa M. Grana; Carolyn I. Sartor; Adrienne D. Cox
View articletitled, Epidermal Growth Factor Receptor Autocrine Signaling in RIE-1 Cells Transformed by the Ras Oncogene Enhances Radiation Resistance
Open the PDF for in another window
Keratinocyte Growth Conditions Modulate Telomerase Expression, Senescence, and Immortalization by Human Papillomavirus Type 16 E6 and E7 Oncogenes
Baojin Fu; Jesse Quintero; Carl C. Baker
View articletitled, Keratinocyte Growth Conditions Modulate Telomerase Expression, Senescence, and Immortalization by Human Papillomavirus Type 16 E6 and E7 Oncogenes
Open the PDF for in another window
Benzo(a)pyrene Quinones Increase Cell Proliferation, Generate Reactive Oxygen Species, and Transactivate the Epidermal Growth Factor Receptor in Breast Epithelial Cells
Andrew D. Burdick; John W. Davis, II; Ke Jian Liu; Laurie G. Hudson; Honglian Shi; Michael L. Monske; Scott W. Burchiel
View articletitled, Benzo(<strong><em>a</em></strong>)pyrene Quinones Increase Cell Proliferation, Generate Reactive Oxygen Species, and Transactivate the Epidermal Growth Factor Receptor in Breast Epithelial Cells
Open the PDF for in another window
Antitumor Effects of a Soluble Insulin-Like Growth Factor I Receptor in Human Ovarian Cancer Cells: Advantage of Recombinant Protein Administration in Vivo
Atsushi Hongo; Hiroyuki Kuramoto; Yojiro Nakamura; Kosei Hasegawa; Keiichiro Nakamura; Junichi Kodama; Yuji Hiramatsu
View articletitled, Antitumor Effects of a Soluble Insulin-Like Growth Factor I Receptor in Human Ovarian Cancer Cells<span class="subtitle-colon">: </span><span class="subtitle">Advantage of Recombinant Protein Administration <strong><em>in Vivo</em></strong></span>
Open the PDF for in another window

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Probasin Promoter (ARR2PB)-Driven, Prostate-Specific Expression of the Human Sodium Iodide Symporter (h-NIS) for Targeted Radioiodine Therapy of Prostate Cancer
Hideaki Kakinuma; Elizabeth R. Bergert; Christine Spitzweg; John C. Cheville; Michael M. Lieber; John C. Morris
View articletitled, Probasin Promoter (ARR<sub>2</sub>PB)-Driven, Prostate-Specific Expression of the Human Sodium Iodide Symporter (<strong><em>h-NIS</em></strong>) for Targeted Radioiodine Therapy of Prostate Cancer
Open the PDF for in another window
Use of Cyclooxygenase-2 Inhibition to Enhance the Efficacy of Immunotherapy
Peter DeLong; Tomoyuki Tanaka; Robb Kruklitis; Adam C. Henry; Veena Kapoor; Larry R. Kaiser; Dan H. Sterman; Steven M. Albelda
View articletitled, Use of Cyclooxygenase-2 Inhibition to Enhance the Efficacy of Immunotherapy
Open the PDF for in another window
Macrophages Transduced with an Adenoviral Vector Expressing Interleukin 12 Suppress Tumor Growth and Metastasis in a Preclinical Metastatic Prostate Cancer Model
Takefumi Satoh; Takashi Saika; Shin Ebara; Nobuyuki Kusaka; Terry L. Timme; Guang Yang; Jianxiang Wang; Vladimir Mouraviev; Guangwen Cao; El Moataz Abdel Fattah; Timothy C. Thompson
View articletitled, Macrophages Transduced with an Adenoviral Vector Expressing Interleukin 12 Suppress Tumor Growth and Metastasis in a Preclinical Metastatic Prostate Cancer Model
Open the PDF for in another window
Tumor Suppression by a Rationally Designed Reversible Inhibitor of Methionine Aminopeptidase-2
Jieyi Wang; George S. Sheppard; Pingping Lou; Megumi Kawai; Nwe BaMaung; Scott A. Erickson; Lora Tucker-Garcia; Chang Park; Jennifer Bouska; Yi-Chun Wang; David Frost; Paul Tapang; Daniel H. Albert; Sherry J. Morgan; Michael Morowitz; Suzanne Shusterman; John M. Maris; Rick Lesniewski; Jack Henkin
View articletitled, Tumor Suppression by a Rationally Designed Reversible Inhibitor of Methionine Aminopeptidase-2
Open the PDF for in another window
Near-Infrared Optical Imaging of Epidermal Growth Factor Receptor in Breast Cancer Xenografts
Shi Ke; Xiaoxia Wen; Michael Gurfinkel; Chusilp Charnsangavej; Sidney Wallace; Eva M. Sevick-Muraca; Chun Li
View articletitled, Near-Infrared Optical Imaging of Epidermal Growth Factor Receptor in Breast Cancer Xenografts
Open the PDF for in another window
Free and N-(2-Hydroxypropyl)methacrylamide Copolymer-bound Geldanamycin Derivative Induce Different Stress Responses in A2780 Human Ovarian Carcinoma Cells
Nobuhiro Nishiyama; Aparna Nori; Alexander Malugin; Yuji Kasuya; Pavla Kopečková; Jindřich Kopeček
View articletitled, Free and <strong><em>N</em></strong>-(2-Hydroxypropyl)methacrylamide Copolymer-bound Geldanamycin Derivative Induce Different Stress Responses in A2780 Human Ovarian Carcinoma Cells
Open the PDF for in another window
Soluble Receptor Activator of Nuclear Factor κB Fc Diminishes Prostate Cancer Progression in Bone
Jian Zhang; Jinlu Dai; Zhi Yao; Yi Lu; William Dougall; Evan T. Keller
View articletitled, Soluble Receptor Activator of Nuclear Factor κB Fc Diminishes Prostate Cancer Progression in Bone
Open the PDF for in another window
Gene Expression and Mitotic Exit Induced by Microtubule-Stabilizing Drugs
Jie-Guang Chen; Chia-Ping Huang Yang; Michael Cammer; Susan Band Horwitz
View articletitled, Gene Expression and Mitotic Exit Induced by Microtubule-Stabilizing Drugs
Open the PDF for in another window
Genotypic and Phenotypic Comparisons of de Novo and Acquired Melphalan Resistance in an Isogenic Multiple Myeloma Cell Line Model
Lori A. Hazlehurst; Steven A. Enkemann; Craig A. Beam; Raul F. Argilagos; Jeffrey Painter; Kenneth H. Shain; Sara Saporta; David Boulware; Lynn Moscinski; Melissa Alsina; William S. Dalton
View articletitled, Genotypic and Phenotypic Comparisons of <strong><em>de Novo</em></strong> and Acquired Melphalan Resistance in an Isogenic Multiple Myeloma Cell Line Model
Open the PDF for in another window
Differential EphA2 Epitope Display on Normal versus Malignant Cells
Karen T. Coffman; Min Hu; Kelly Carles-Kinch; David Tice; Nanci Donacki; Karyn Munyon; Giza Kifle; Robert Woods; Solomon Langermann; Peter A. Kiener; Michael S. Kinch
View articletitled, Differential EphA2 Epitope Display on Normal <strong><em>versus</em></strong> Malignant Cells
Open the PDF for in another window
Antagonists of Growth Hormone-Releasing Hormone Inhibit the Proliferation of Experimental Non-Small Cell Lung Carcinoma
Zoltan Szereday; Andrew V. Schally; Jozsef L. Varga; Celia A. Kanashiro; Francine Hebert; Patricia Armatis; Kate Groot; Karoly Szepeshazi; Gabor Halmos; Rebeca Busto
View articletitled, Antagonists of Growth Hormone-Releasing Hormone Inhibit the Proliferation of Experimental Non-Small Cell Lung Carcinoma
Open the PDF for in another window
Deoxyribonucleic Acid (DNA) Encoding a Pan-Major Histocompatibility Complex Class II Peptide Analogue Augmented Antigen-specific Cellular Immunity and Suppressive Effects on Tumor Growth Elicited by DNA Vaccine Immunotherapy
Koji Teramoto; Keiichi Kontani; Yoshitomo Ozaki; Satoru Sawai; Noriaki Tezuka; Toshi Nagata; Shozo Fujino; Yasushi Itoh; Osamu Taguchi; Yukio Koide; Tohru Asai; Iwao Ohkubo; Kazumasa Ogasawara
View articletitled, Deoxyribonucleic Acid (DNA) Encoding a Pan-Major Histocompatibility Complex Class II Peptide Analogue Augmented Antigen-specific Cellular Immunity and Suppressive Effects on Tumor Growth Elicited by DNA Vaccine Immunotherapy
Open the PDF for in another window
Both Hepatocyte Growth Factor (HGF) and Stromal-Derived Factor-1 Regulate the Metastatic Behavior of Human Rhabdomyosarcoma Cells, But Only HGF Enhances Their Resistance to Radiochemotherapy
Kacper Jankowski; Magda Kucia; Marcin Wysoczynski; Ryan Reca; Dongling Zhao; Ela Trzyna; John Trent; Stephen Peiper; Marek Zembala; Janina Ratajczak; Peter Houghton; Anna Janowska-Wieczorek; Mariusz Z. Ratajczak
View articletitled, Both Hepatocyte Growth Factor (HGF) and Stromal-Derived Factor-1 Regulate the Metastatic Behavior of Human Rhabdomyosarcoma Cells, But Only HGF Enhances Their Resistance to Radiochemotherapy
Open the PDF for in another window
Replication of an Adenoviral Vector Controlled by the Human Telomerase Reverse Transcriptase Promoter Causes Tumor-Selective Tumor Lysis
Nicholas A. Lanson, Jr.; Paul L. Friedlander; Paul Schwarzenberger; Jay K. Kolls; Guoshun Wang
View articletitled, Replication of an Adenoviral Vector Controlled by the Human Telomerase Reverse Transcriptase Promoter Causes Tumor-Selective Tumor Lysis
Supplementary data
Open the PDF for in another window
Modified Vaccinia Virus Ankara Recombinants Are as Potent as Vaccinia Recombinants in Diversified Prime and Boost Vaccine Regimens to Elicit Therapeutic Antitumor Responses
James W. Hodge; Diane J. Poole; Wilhelmina M. Aarts; Alicia Gómez Yafal; Linda Gritz; Jeffrey Schlom
View articletitled, Modified Vaccinia Virus Ankara Recombinants Are as Potent as Vaccinia Recombinants in Diversified Prime and Boost Vaccine Regimens to Elicit Therapeutic Antitumor Responses
Open the PDF for in another window
Arsenic Trioxide Inhibits Translation of mRNA of bcr-abl, Resulting in Attenuation of Bcr-Abl Levels and Apoptosis of Human Leukemia Cells
Ramadevi Nimmanapalli; Purva Bali; Erica O’Bryan; Lianne Fuino; Fei Guo; Jie Wu; Peter Houghton; Kapil Bhalla
View articletitled, Arsenic Trioxide Inhibits Translation of mRNA of <strong><em>bcr-abl</em></strong>, Resulting in Attenuation of Bcr-Abl Levels and Apoptosis of Human Leukemia Cells
Open the PDF for in another window
Rac1 and Rac3 Are Targets for Geranylgeranyltransferase I Inhibitor-Mediated Inhibition of Signaling, Transformation, and Membrane Ruffling
Patricia L. Joyce; Adrienne D. Cox
View articletitled, Rac1 and Rac3 Are Targets for Geranylgeranyltransferase I Inhibitor-Mediated Inhibition of Signaling, Transformation, and Membrane Ruffling
Open the PDF for in another window
RNA-Directed Actions of 8-Chloro-Adenosine in Multiple Myeloma Cells
Christine M. Stellrecht; Carlos O. Rodriguez, Jr.; Mary Ayres; Varsha Gandhi
View articletitled, RNA-Directed Actions of 8-Chloro-Adenosine in Multiple Myeloma Cells
Open the PDF for in another window
Potent Inhibitor of N-Myristoylation: A Novel Molecular Target For Cancer
Anuraag Shrivastav; Mohammed K. Pasha; Ponniah Selvakumar; Sweta Gowda; Douglas J. H. Olson; Andrew R. S. Ross; Jonathan R. Dimmock; Rajendra K. Sharma
View articletitled, Potent Inhibitor of <strong><em>N</em></strong>-Myristoylation<span class="subtitle-colon">: </span><span class="subtitle">A Novel Molecular Target For Cancer</span>
Open the PDF for in another window
The Cytoplasmic Domain Is Critical to the Tumor Suppressor Activity of TSLC1 in Non-Small Cell Lung Cancer
Xinliang Mao; Eric Seidlitz; Kakoli Ghosh; Yoshinori Murakami; Hara P. Ghosh
View articletitled, The Cytoplasmic Domain Is Critical to the Tumor Suppressor Activity of TSLC1 in Non-Small Cell Lung Cancer
Open the PDF for in another window
In Vitro Tests of the Validity of Singlet Oxygen Luminescence Measurements as a Dose Metric in Photodynamic Therapy
Mark J. Niedre; Andrea J. Secord; Michael S. Patterson; Brian C. Wilson
View articletitled, <strong><em>In Vitro</em></strong> Tests of the Validity of Singlet Oxygen Luminescence Measurements as a Dose Metric in Photodynamic Therapy
Open the PDF for in another window

Immunology

Natural IgM Antibodies and Immunosurveillance Mechanisms against Epithelial Cancer Cells in Humans
Stephanie Brändlein; Tina Pohle; Nele Ruoff; Ewa Wozniak; Hans-Konrad Müller-Hermelink; H. Peter Vollmers
View articletitled, Natural IgM Antibodies and Immunosurveillance Mechanisms against Epithelial Cancer Cells in Humans
Open the PDF for in another window
Retinoids Act as Multistep Modulators of the Major Histocompatibility Class I Presentation Pathway and Sensitize Neuroblastomas to Cytotoxic Lymphocytes
Simona Vertuani; Anna De Geer; Victor Levitsky; Per Kogner; Rolf Kiessling; Jelena Levitskaya
View articletitled, Retinoids Act as Multistep Modulators of the Major Histocompatibility Class I Presentation Pathway and Sensitize Neuroblastomas to Cytotoxic Lymphocytes
Open the PDF for in another window
Antitumor Activity Mediated by Double-Negative T Cells
Kevin J. Young; Lyndsey S. Kay; M. James Phillips; Li Zhang
View articletitled, Antitumor Activity Mediated by Double-Negative T Cells
Open the PDF for in another window

Endocrinology

Parathyroid Gland-specific Deletion of the Mouse Men1 Gene Results in Parathyroid Neoplasia and Hypercalcemic Hyperparathyroidism
Steven K. Libutti; Judy S. Crabtree; Dominique Lorang; A. Lee Burns; Chiara Mazzanti; Stephen M. Hewitt; Sarah O’Connor; Jerrold M. Ward; Michael R. Emmert-Buck; Alan Remaley; Marshall Miller; Ewa Turner; H. Richard Alexander; Andrew Arnold; Stephen J. Marx; Francis S. Collins; Allen M. Spiegel
View articletitled, Parathyroid Gland-specific Deletion of the Mouse <strong><em>Men1</em></strong> Gene Results in Parathyroid Neoplasia and Hypercalcemic Hyperparathyroidism
Open the PDF for in another window
Pharmacological Uncoupling of Androgen Receptor-mediated Prostate Cancer Cell Proliferation and Prostate-specific Antigen Secretion
Ganesan Sathya; Ching-yi Chang; Dmitri Kazmin; C. Edgar Cook; Donald P. McDonnell
View articletitled, Pharmacological Uncoupling of Androgen Receptor-mediated Prostate Cancer Cell Proliferation and Prostate-specific Antigen Secretion
Open the PDF for in another window
Signaling Pathways of Apoptosis Activated by Aromatase Inhibitors and Antiestrogens
Apinya Thiantanawat; Brian J. Long; Angela M. Brodie
View articletitled, Signaling Pathways of Apoptosis Activated by Aromatase Inhibitors and Antiestrogens
Open the PDF for in another window

Clinical Research

Interleukin-6 −174G→C Polymorphism Is Associated with Improved Outcome in High-Risk Breast Cancer
Angela DeMichele; Anne-Marie Martin; Rosemarie Mick; Priya Gor; Lisa Wray; Melissa Klein-Cabral; Galene Athanasiadis; Theresa Colligan; Edward Stadtmauer; Barbara Weber
View articletitled, Interleukin-6 −174G→C Polymorphism Is Associated with Improved Outcome in High-Risk Breast Cancer
Open the PDF for in another window

Epidemiology and Prevention

Substantial Reduction in Risk of Lung Adenocarcinoma Associated with Genetic Polymorphism in CYP2A13, the Most Active Cytochrome P450 for the Metabolic Activation of Tobacco-Specific Carcinogen NNK
Haijian Wang; Wen Tan; Bingtao Hao; Xiaoping Miao; Gangqiao Zhou; Fuchu He; Dongxin Lin
View articletitled, Substantial Reduction in Risk of Lung Adenocarcinoma Associated with Genetic Polymorphism in CYP2A13, the Most Active Cytochrome P450 for the Metabolic Activation of Tobacco-Specific Carcinogen NNK
Open the PDF for in another window
St. John’s Wort Extracts and Some of Their Constituents Potently Inhibit Ultimate Carcinogen Formation from Benzo[a]pyrene-7,8-Dihydrodiol by Human CYP1A1
Dieter Schwarz; Pyotr Kisselev; Ivar Roots
View articletitled, St. John’s Wort Extracts and Some of Their Constituents Potently Inhibit Ultimate Carcinogen Formation from Benzo[<strong><em>a</em></strong>]pyrene-7,8-Dihydrodiol by Human CYP1A1
Open the PDF for in another window

Meeting Report

Meeting Report on the Ninth Conference on Cancer Therapy with Antibodies and Immunoconjugates
Robert M. Sharkey; Edward A. Sausville; David M. Goldenberg
View articletitled, Meeting Report on the Ninth Conference on Cancer Therapy with Antibodies and Immunoconjugates
Supplementary data
Open the PDF for in another window

Advertisement

Email alerts

eTOC Alert
Close Modal
  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

AACR Journals

 

 

  • Copyright © 2023 by the American Association for Cancer Research.
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept