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Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

Phosphoinositide 3-Kinase Regulates Membrane Type 1-Matrix Metalloproteinase (MMP) and MMP-2 Activity during Melanoma Cell Vasculogenic Mimicry 1

Angela R. Hess; Elisabeth A. Seftor; Richard E. B. Seftor; Mary J. C. Hendrix

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Estrous Cycle Influences Organ-specific Metastasis of B16F10 Melanoma Cells 1

Sharon A. Vantyghem; Carl O. Postenka; Ann F. Chambers

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Intracellular Visualization of Prostate Cancer Using Magnetic Resonance Imaging

Stefan Heckl; Rüdiger Pipkorn; Waldemar Waldeck; Herbert Spring; Jürgen Jenne; Claus-W. von der Lieth; Heike Corban-Wilhelm; Jürgen Debus; Klaus Braun

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c-Myc Promoter Activation in Medulloblastoma 1

I-Mei Siu; Anita Lal; Jill R. Blankenship; Naji Aldosari; Gregory J. Riggins

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Modulation of Medullary Thyroid Carcinoma Penetrance Suggests the Presence of Modifier Genes in a RET Transgenic Mouse Model 1

Aaron N. Cranston; Bruce A. J. Ponder

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Genome-wide Loss of Heterozygosity Analysis from Laser Capture Microdissected Prostate Cancer Using Single Nucleotide Polymorphic Allele (SNP) Arrays and a Novel Bioinformatics Platform dChipSNP 1^,2

Marshall E. Lieberfarb; Ming Lin; Mirna Lechpammer; Cheng Li; David M. Tanenbaum; Phillip G. Febbo; Renée L. Wright; Judy Shim; Philip W. Kantoff; Massimo Loda; Matthew Meyerson; William R. Sellers

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Modulation of Prostate Cancer Cell Attachment to Matrix by Versican 1

Andrew J. Sakko; Carmela Ricciardelli; Keiko Mayne; Supaporn Suwiwat; Richard G. LeBaron; Villis R. Marshall; Wayne D. Tilley; David J. Horsfall

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BP75, Bromodomain-containing M_r 75,000 Protein, Binds Dishevelled-1 and Enhances Wnt Signaling by Inactivating Glycogen Synthase Kinase-3β 1

Sunhong Kim; Jiwoon Lee; Jeehye Park; Jongkyeong Chung

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Implication of Protein Kinase B/Akt and Bcl-2/Bcl-XL Suppression by the Farnesyl Transferase Inhibitor SCH66336 in Apoptosis Induction in Squamous Carcinoma Cells 1

Kyung-Hee Chun; Ho-Young Lee; Khaled Hassan; Fadlo Khuri; Waun Ki Hong; Reuben Lotan

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Down-Regulation of CXCR4 by Inducible Small Interfering RNA Inhibits Breast Cancer Cell Invasion in Vitro1

Yangchao Chen; George Stamatoyannopoulos; Chao-Zhong Song

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Association of the CpG Island Methylator Phenotype with Family History of Cancer in Patients with Colorectal Cancer 1

Marsha L. Frazier; Lixuan Xi; Jihong Zong; Nancy Viscofsky; Asif Rashid; Elsie F. Wu; Patrick M. Lynch; Christopher I. Amos; Jean-Pierre J. Issa

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Molecular Biology, Pathobiology, and Genetics

Identification and Pharmacological Characterization of SRBP-2: A Novel SR31747A-binding Protein

Hubert Vidal; Guillaume Mondesert; Sylvaine Galiègue; Dominique Carrière; Pascal-Henri Dupuy; Pierre Carayon; Thérèse Combes; Estelle Bribes; Joëlle Simony-Lafontaine; Andrew Kramar; Gérard Loison; Pierre Casellas

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Targeted Expression of c-Src in Epidermal Basal Cells Leads to Enhanced Skin Tumor Promotion, Malignant Progression, and Metastasis 1

Takashi Matsumoto; Jianghong Jiang; Kaoru Kiguchi; Lynnsie Ruffino; Steve Carbajal; Linda Beltrán; David K. Bol; Michael P. Rosenberg; John DiGiovanni

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hRad9 Rapidly Binds DNA Containing Double-Strand Breaks and Is Required for Damage-dependent Topoisomerase IIβ Binding Protein 1 Focus Formation 1

Deborah A. Greer; Blair D. A. Besley; Katherine B. Kennedy; Scott Davey

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Pancreatic β-Cell-specific Ablation of the Multiple Endocrine Neoplasia Type 1 (MEN1) Gene Causes Full Penetrance of Insulinoma Development in Mice 1

Philippe Bertolino; Wei-Min Tong; Pedro Luis Herrera; Huguette Casse; Chang Xian Zhang; Zhao-Qi Wang

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Promoter Hypermethylation of the O⁶-Methylguanine-DNA Methyltransferase Gene: More Common in Lung Adenocarcinomas from Never-Smokers than Smokers and Associated with Tumor Progression 1

Leah C. Pulling; Kevin K. Divine; Donna M. Klinge; Frank D. Gilliland; Terri Kang; Ann G. Schwartz; Therese J. Bocklage; Steven A. Belinsky

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Allele-specific Hras Mutations and Genetic Alterations at Tumor Susceptibility Loci in Skin Carcinomas from Interspecific Hybrid Mice 1

Hiroki Nagase; Jian-Hua Mao; Allan Balmain

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A P53-dependent, Telomere-independent Proliferative Life Span Barrier in Human Astrocytes Consistent with the Molecular Genetics of Glioma Development 1

Rebecca J. Evans; Fiona S. Wyllie; David Wynford-Thomas; David Kipling; Christopher J. Jones

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Dissection of Human Papillomavirus E6 and E7 Function in Transgenic Mouse Models of Cervical Carcinogenesis 1

Rebeccah R. Riley; Stefan Duensing; Tiffany Brake; Karl Münger; Paul F. Lambert; Jeffrey M. Arbeit

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Cooperation of Cyclooxygenase 1 and Cyclooxygenase 2 in Intestinal Polyposis 1

Haruna Takeda; Masahiro Sonoshita; Hiroko Oshima; Ken-ichi Sugihara; Patricia C. Chulada; Robert Langenbach; Masanobu Oshima; Makoto M. Taketo

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BRAF and KRAS Mutations in Colorectal Hyperplastic Polyps and Serrated Adenomas 1

Tsun L. Chan; Wei Zhao; Cancer Genome Project; Suet Y. Leung; Siu T. Yuen

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Two Distinct Gene Expression Signatures in Pediatric Acute Lymphoblastic Leukemia with MLL Rearrangements 1

Shuichi Tsutsumi; Takeshi Taketani; Kunihiro Nishimura; Xijin Ge; Tomohiko Taki; Kanji Sugita; Eiichi Ishii; Ryoji Hanada; Misao Ohki; Hiroyuki Aburatani; Yasuhide Hayashi

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Modulation of Androgen Receptor Transactivation by Gelsolin: A Newly Identified Androgen Receptor Coregulator 1

Kazuo Nishimura; Huei-Ju Ting; Yasunori Harada; Takashi Tokizane; Norio Nonomura; Hong-Yo Kang; Hong-Chiang Chang; Shuyuan Yeh; Hiroshi Miyamoto; Masaru Shin; Katsuyuki Aozasa; Akihiko Okuyama; Chawnshang Chang

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Measurement of Genomic Instability in Preleukemic P190^BCR/ABL Transgenic Mice Using Inter-Simple Sequence Repeat Polymerase Chain Reaction 1

Julia M. Brain; Nathaniel Goodyer; Pierre Laneuville

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Products of Oxidative DNA Damage and Repair as Possible Biomarkers of Susceptibility to Lung Cancer 1

Daniel Gackowski; Elzbieta Speina; Maja Zielinska; Janusz Kowalewski; Rafal Rozalski; Agnieszka Siomek; Tomasz Paciorek; Barbara Tudek; Ryszard Olinski

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Specificity of Cyclin D1 for Androgen Receptor Regulation 1

Christin E. Petre-Draviam; Stephen L. Cook; Craig J. Burd; Thomas W. Marshall; Yelena B. Wetherill; Karen E. Knudsen

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C57BR/cdJ Hepatocarcinogen Susceptibility Genes Act Cell-Autonomously in C57BR/cdJ↔C57BL/6J Chimeras 1

Teresa A. Chiaverotti; Norman R. Drinkwater

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Gene Expression Profiling of Neu-induced Mammary Tumors from Transgenic Mice Reveals Genetic and Morphological Similarities to ErbB2-expressing Human Breast Cancers 1

Eran R. Andrechek; Michael A. Laing; Adele A. Girgis-Gabardo; Peter M. Siegel; Robert D. Cardiff; William J. Muller

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The Group 3 LIM Domain Protein Paxillin Potentiates Androgen Receptor Transactivation in Prostate Cancer Cell Lines 1

Masaaki Kasai; Jennifer Guerrero-Santoro; Robert Friedman; Eddy S. Leman; Robert H. Getzenberg; Donald B. DeFranco

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Cell and Tumor Biology

Stromal Cell Heterogeneity in Fibroblast Growth Factor-mediated Stromal-Epithelial Cell Cross-Talk in Premalignant Prostate Tumors 1

Xiaochong Wu; Chengliu Jin; Fen Wang; Chundong Yu; Wallace L. McKeehan

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SERPINE2 (Protease Nexin I) Promotes Extracellular Matrix Production and Local Invasion of Pancreatic Tumors in Vivo1

Malte Buchholz; Anja Biebl; Albrecht Neeβe; Martin Wagner; Takeshi Iwamura; Gerhard Leder; Guido Adler; Thomas M. Gress

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LABAZ1: A Metastatic Tumor Model for Renal Cell Carcinoma Expressing the Carbonic Anhydrase Type 9 Tumor Antigen

Amnon Zisman; Allan J. Pantuck; Matthew H. T. Bui; Jonathan W. Said; Randy R. Caliliw; Nagesh Rao; Peter Shintaku; Frank Berger; Sanjiv S. Gambhir; Arie S. Belldegrun

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Effects of Overexpression of Dimethylarginine Dimethylaminohydrolase on Tumor Angiogenesis Assessed by Susceptibility Magnetic Resonance Imaging 1

Vassiliki Kostourou; Simon P. Robinson; Guy St. J. Whitley; John R. Griffiths

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Anomalous Expression of Epithelial Differentiation-determining GATA Factors in Ovarian Tumorigenesis 1

Callinice D. Capo-chichi; Isabelle H. Roland; Lisa Vanderveer; Rudi Bao; Tetsuya Yamagata; Hisamaru Hirai; Cynthia Cohen; Thomas C. Hamilton; Andrew K. Godwin; Xiang-Xi Xu

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Haplo-insufficiency of BRCA1 in Sporadic Breast Cancer 1

Synnöve Staff; Jorma Isola; Minna Tanner

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Procaine Is a DNA-demethylating Agent with Growth-inhibitory Effects in Human Cancer Cells 1

Ana Villar-Garea; Mario F. Fraga; Jesus Espada; Manel Esteller

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Targeted Inactivation of p27^kip1 Is Sufficient for Large and Small Intestinal Tumorigenesis in the Mouse, Which Can Be Augmented by a Western-Style High-Risk Diet 1

WanCai Yang; Laura Bancroft; Courtney Nicholas; Ioana Lozonschi; Leonard H. Augenlicht

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Overexpression of the Calcium Sensor Visinin-like Protein-1 Leads to a cAMP-mediated Decrease of in Vivo and in Vitro Growth and Invasiveness of Squamous Cell Carcinoma Cells 1

Haleh Mahloogi; Anatilde M. González-Guerrico; Ricardo Lopez De Cicco; Daniel E. Bassi; Tamra Goodrow; Karl-Heinz Braunewell; Andres J. P. Klein-Szanto

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Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas 1,²

Fan Zhang; Mikael Lundin; Ari Ristimäki; Päivi Heikkilä; Johan Lundin; Jorma Isola; Heikki Joensuu; Marikki Laiho

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Contribution of the MUC1 Tandem Repeat and Cytoplasmic Tail to Invasive and Metastatic Properties of a Pancreatic Cancer Cell Line 1

Karl G. Kohlgraf; Andrew J. Gawron; Michiyo Higashi; Jane L. Meza; Michael D. Burdick; Shinichi Kitajima; David L. Kelly; Thomas C. Caffrey; Michael A. Hollingsworth

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Differential Impact of Telomere Dysfunction on Initiation and Progression of Hepatocellular Carcinoma 1

Paraskevi A. Farazi; Jonathan Glickman; Shan Jiang; Alice Yu; Karl Lenhard Rudolph; Ronald A. DePinho

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C-Src Tyrosine Kinase Activity Is Associated with Tumor Colonization in Bone and Lung in an Animal Model of Human Breast Cancer Metastasis 1

Akira Myoui; Riko Nishimura; Paul J. Williams; Toru Hiraga; Daisuke Tamura; Toshimi Michigami; Gregory R. Mundy; Toshiyuki Yoneda

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Macrophage Inhibitory Cytokine 1 Reduces Cell Adhesion and Induces Apoptosis in Prostate Cancer Cells 1

Tao Liu; Asne R. Bauskin; John Zaunders; David A. Brown; Susan Pankurst; Pamela J. Russell; Samuel N. Breit

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Local Estrogen Formation by Nontumoral, Cirrhotic, and Malignant Human Liver Tissues and Cells

Luigi A. M. Castagnetta; Biagio Agostara; Giuseppe Montalto; Lucia Polito; Ildegarda Campisi; Annalisa Saetta; Toru Itoh; Bin Yu; Shiuan Chen; Giuseppe Carruba

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Experimental Therapeutics, Molecular Targets, and Chemical Biology

Comparison of Three Different Targeted Tissue Factor Fusion Proteins for Inducing Tumor Vessel Thrombosis 1

Peisheng Hu; Jianghua Yan; Jahangir Sharifi; Thomas Bai; Leslie A. Khawli; Alan L. Epstein

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Augments a Murine Model of Pulmonary Fibrosis 1

Hiroko Suzuki; Kazutetsu Aoshiba; Naoko Yokohori; Atsushi Nagai

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Identification of a Potent Peptide Antagonist to an Active Laminin-1 Sequence That Blocks Angiogenesis and Tumor Growth

M. Lourdes Ponce; Suguru Hibino; Agata M. Lebioda; Mayumi Mochizuki; Motoyoshi Nomizu; Hynda K. Kleinman

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Nonradioactive Iodide Effectively Induces Apoptosis in Genetically Modified Lung Cancer Cells 1

Ling Zhang; Sherven Sharma; Li X. Zhu; Takahiko Kogai; Jerome M. Hershman; Gregory A. Brent; Steven M. Dubinett; Min Huang

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An Anti-Insulin-like Growth Factor I Receptor Antibody That Is a Potent Inhibitor of Cancer Cell Proliferation

Erin K. Maloney; Jennifer L. McLaughlin; Nancy E. Dagdigian; Lisa M. Garrett; Katherine M. Connors; Xiao-Mai Zhou; Walter A. Blättler; Thomas Chittenden; Rajeeva Singh

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Targeted Actinium-225 in Vivo Generators for Therapy of Ovarian Cancer 1

Paul E. Borchardt; Rui R. Yuan; Matthias Miederer; Michael R. McDevitt; David A. Scheinberg

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Interleukin-10-mediated Inhibition of Angiogenesis and Tumor Growth in Mice Bearing VEGF-producing Ovarian Cancer 1

Takahiro Kohno; Hiroaki Mizukami; Mitsuaki Suzuki; Yasushi Saga; Yuji Takei; Masahisa Shimpo; Takashi Matsushita; Takashi Okada; Yutaka Hanazono; Akihiro Kume; Ikuo Sato; Keiya Ozawa

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Transcriptional Profiling of Targets for Combination Therapy of Lung Carcinoma with Paclitaxel and Mitogen-activated Protein/Extracellular Signal-regulated Kinase Kinase Inhibitor 1

Debra J. Taxman; Jeffrey P. MacKeigan; Casey Clements; Daniel T. Bergstralh; Jenny P-Y. Ting

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Melanoma Differentiation-associated Gene 7/Interleukin (IL)-24 Is a Novel Ligand That Regulates Angiogenesis via the IL-22 Receptor 1

Rajagopal Ramesh; Abner M. Mhashilkar; Fumihiro Tanaka; Yuji Saito; Cynthia D. Branch; Kerry Sieger; John B. Mumm; Alexis L. Stewart; Amelia Boquio; Laure Dumoutier; Elizabeth A. Grimm; Jean-Christophe Renauld; Sergei Kotenko; Sunil Chada

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The Effect of P-glycoprotein on Paclitaxel Brain and Brain Tumor Distribution in Mice 1

James M. Gallo; Shaolan Li; Ping Guo; Karin Reed; Jianguo Ma

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Rottlerin Sensitizes Colon Carcinoma Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis via Uncoupling of the Mitochondria Independent of Protein Kinase C 1

David M. Tillman; Kamel Izeradjene; Kinga Szekely Szucs; Leslie Douglas; Janet A. Houghton

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Histone Deacetylase Inhibitor LAQ824 Both Lowers Expression and Promotes Proteasomal Degradation of Bcr-Abl and Induces Apoptosis of Imatinib Mesylate-sensitive or -refractory Chronic Myelogenous Leukemia-Blast Crisis Cells

Ramadevi Nimmanapalli; Lianne Fuino; Purva Bali; Maura Gasparetto; Michele Glozak; Jianguo Tao; Lynn Moscinski; Clayton Smith; Jie Wu; Richard Jove; Peter Atadja; Kapil Bhalla

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Immunology

Intestinal Immune Responses in Wild-Type and Apc^Min/+ Mouse, a Model for Colon Cancer 1

Hannele L. Kettunen; Anu S. L. Kettunen; Nina E. Rautonen

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The Differential Influence of Allogeneic Tumor Cell Death via DNA Damage on Dendritic Cell Maturation and Antigen Presentation

Ariel N. Rad; Gabriele Pollara; S. M. Afzal Sohaib; Cheryl Chiang; Benjamin M. Chain; David R. Katz

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Endocrinology

Identification of a Novel Inhibitor of Breast Cell Growth That Is Down-Regulated by Estrogens and Decreased in Breast Tumors 1

Bryan M. Wittmann; Nancy Wang; Monica M. Montano

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Clinical Research

Profiling Gene Expression Ratios of Paired Cancerous and Normal Tissue Predicts Relapse of Esophageal Squamous Cell Carcinoma

Yoshio Ishibashi; Nobuyoshi Hanyu; Koji Nakada; Yutaka Suzuki; Takashi Yamamoto; Katsuhiko Yanaga; Kiyoshi Ohkawa; Noriko Hashimoto; Toshiharu Nakajima; Hirohisa Saito; Masato Matsushima; Mitsuyoshi Urashima

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Letters to the Editor

Correspondence re: Somasundaram et al., Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer. Cancer Res., 62: 3868–3875, 2002.

Terri M. Mitchell

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Correspondence re: M. P. Rosin et al., 3p14 and 9p21 Loss Is a Simple Tool for Predicting Second Oral Malignancy at Previously Treated Oral Cancer Sites. Cancer Res., 62: 6447–6450, 2002.

Boudewijn J. M. Braakhuis; C. René Leemans; Ruud H. Brakenhoff

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Issues

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Journal Archive

Table of Contents

Advances in Brief

Molecular Biology, Pathobiology, and Genetics

Cell and Tumor Biology

Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas1,2

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Immunology

Endocrinology

Clinical Research

Letters to the Editor

Correction

Erratum

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only

Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas 1,²