Skip to Main Content

Advertisement

Close

AACR Journals
For Authors
About Us
Article Collections
Cancer Hallmarks
Webinars

header search

search input Search input auto suggest

Search

Advanced Search

Menu

About
Articles
For Authors
Alerts
News
Cancer Hallmarks
Webinars

Skip Nav Destination

Issues

Select Decade

Select Year

Issue

Volume 63, Issue 14

15 July 2003

Cover Image

Cover Image

ISSN 0008-5472

EISSN 1538-7445

Issue Sections

Perspectives in Cancer Research
Advances in Brief
Biochemistry and Biophysics
Carcinogenesis
Clinical Investigations
Epidemiology and Prevention
Experimental Therapeutics
Immunology
Molecular Biology and Genetics
Tumor Biology

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Perspectives in Cancer Research

The Glycolytic Phenotype in Carcinogenesis and Tumor Invasion: Insights through Mathematical Models

Robert A. Gatenby; Edward T. Gawlinski

View articletitled, The Glycolytic Phenotype in Carcinogenesis and Tumor Invasion<span class="subtitle-colon">: </span><span class="subtitle">Insights through Mathematical Models</span>

Open the PDF for in another window

Advances in Brief

Direct Demonstration of Negative Regulation of Tumor Growth and Metastasis by Host-inducible Nitric Oxide Synthase 1

Daoyan Wei; Erica L. Richardson; Keyi Zhu; Liwei Wang; Xiangdong Le; Yanjuan He; Suyun Huang; Keping Xie

View articletitled, Direct Demonstration of Negative Regulation of Tumor Growth and Metastasis by Host-inducible Nitric Oxide Synthase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Glucosylceramide Synthase and Its Functional Interaction with RTN-1C Regulate Chemotherapeutic-induced Apoptosis in Neuroepithelioma Cells 1

Federica Di Sano; Barbara Fazi; Gennaro Citro; Penny E. Lovat; Gianni Cesareni; Mauro Piacentini

View articletitled, Glucosylceramide Synthase and Its Functional Interaction with RTN-1C Regulate Chemotherapeutic-induced Apoptosis in Neuroepithelioma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Detection of Mitochondrial DNA Mutations in the Tumor and Cerebrospinal Fluid of Medulloblastoma Patients 1

Lee-Jun C. Wong; Maria Lueth; Xiao-Nan Li; Ching C. Lau; Hannes Vogel

View articletitled, Detection of Mitochondrial DNA Mutations in the Tumor and Cerebrospinal Fluid of Medulloblastoma Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Gene Expression Analysis of Esophageal Squamous Cell Carcinoma Reveals Consistent Molecular Profiles Related to a Family History of Upper Gastrointestinal Cancer

Hua Su; Nan Hu; Joanna Shih; Ying Hu; Quan-Hong Wang; Eric Y. Chuang; Mark J. Roth; Chaoyu Wang; Alisa M. Goldstein; Ti Ding; Sanford M. Dawsey; Carol Giffen; Michael R. Emmert-Buck; Philip R. Taylor

View articletitled, Gene Expression Analysis of Esophageal Squamous Cell Carcinoma Reveals Consistent Molecular Profiles Related to a Family History of Upper Gastrointestinal Cancer

Open the PDF for in another window

Transcriptional Silencing of Zinc Finger Protein 185 Identified by Expression Profiling Is Associated with Prostate Cancer Progression 1

Donkena Krishna Vanaja; John C. Cheville; Steve J. Iturria; Charles Y. F. Young

View articletitled, Transcriptional Silencing of Zinc Finger Protein 185 Identified by Expression Profiling Is Associated with Prostate Cancer Progression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

BRAF Oncogenic Mutations Correlate with Progression rather than Initiation of Human Melanoma 1

Jianli Dong; Robert G. Phelps; Rui Qiao; Shen Yao; Outhiriaradjou Benard; Zeev Ronai; Stuart A. Aaronson

View articletitled, <strong><em>BRAF</em></strong> Oncogenic Mutations Correlate with Progression rather than Initiation of Human Melanoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Nkx3.1; Pten Mutant Mice Develop Invasive Prostate Adenocarcinoma and Lymph Node Metastases 1

Cory Abate-Shen; Whitney A. Banach-Petrosky; Xiaohui Sun; Kyriakos D. Economides; Nishita Desai; Jeffery P. Gregg; Alexander D. Borowsky; Robert D. Cardiff; Michael M. Shen

View articletitled, <strong><em>Nkx3.1</em></strong>; <strong><em>Pten</em></strong> Mutant Mice Develop Invasive Prostate Adenocarcinoma and Lymph Node Metastases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Association between Cyclooxygenase Expression and Colorectal Adenoma Characteristics 1

Janine G. Einspahr; Robert S. Krouse; Ji Min Yochim; Peter V. Danenberg; Kathleen D. Danenberg; Achyut K. Bhattacharyya; María E. Martínez; David S. Alberts

View articletitled, Association between <strong><em>Cyclooxygenase</em></strong> Expression and Colorectal Adenoma Characteristics<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Expression of Activation-induced Cytidine Deaminase Is Confined to B-Cell Non-Hodgkin’s Lymphomas of Germinal-Center Phenotype

Laura A. Smit; Richard J. Bende; Jan Aten; Jeroen E. J. Guikema; Wilhelmina M. Aarts; Carel J. M. van Noesel

View articletitled, Expression of Activation-induced Cytidine Deaminase Is Confined to B-Cell Non-Hodgkin’s Lymphomas of Germinal-Center Phenotype

Open the PDF for in another window

Stimulation of Estrogen Receptor Signaling by γ Synuclein 1

Yangfu Jiang; Yiliang Ellie Liu; AiPing Lu; Anu Gupta; Itzhak D. Goldberg; Jingwen Liu; Y. Eric Shi

View articletitled, Stimulation of Estrogen Receptor Signaling by γ Synuclein<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Reactivation of Mutant p53 by a One-Hybrid Adaptor Protein 1

Judith Roth; Claudia Lenz-Bauer; Ana Contente; Kristina Löhr; Philipp Koch; Sandra Bernard; Matthias Dobbelstein

View articletitled, Reactivation of Mutant p53 by a One-Hybrid Adaptor Protein<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Recapitulation of the Cellular Xeroderma Pigmentosum-Variant Phenotypes Using Short Interfering RNA for DNA Polymerase Η 1

Rebecca R. Laposa; Luzviminda Feeney; James E. Cleaver

View articletitled, Recapitulation of the Cellular Xeroderma Pigmentosum-Variant Phenotypes Using Short Interfering RNA for DNA Polymerase Η<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

CYP1B1 Gene Polymorphisms Have Higher Risk for Endometrial Cancer, and Positive Correlations with Estrogen Receptor α and Estrogen Receptor β Expressions

Masahiro Sasaki; Yuichiro Tanaka; Masanori Kaneuchi; Noriaki Sakuragi; Rajvir Dahiya

View articletitled, CYP1B1 Gene Polymorphisms Have Higher Risk for Endometrial Cancer, and Positive Correlations with Estrogen Receptor α and Estrogen Receptor β Expressions

Open the PDF for in another window

SiRNA-mediated Inhibition of Vascular Endothelial Growth Factor Severely Limits Tumor Resistance to Antiangiogenic Thrombospondin-1 and Slows Tumor Vascularization and Growth 1

Stéphanie Filleur; Aurélie Courtin; Slimane Ait-Si-Ali; Julien Guglielmi; Carole Merle; Annick Harel-Bellan; Philippe Clézardin; Florence Cabon

View articletitled, SiRNA-mediated Inhibition of Vascular Endothelial Growth Factor Severely Limits Tumor Resistance to Antiangiogenic Thrombospondin-1 and Slows Tumor Vascularization and Growth<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Biochemistry and Biophysics

Identification and Characterization of Signal Transducer and Activator of Transcription 3 Recruitment Sites within the Epidermal Growth Factor Receptor 1

Huang Shao; Haiyun Y. Cheng; Richard G. Cook; David J. Tweardy

View articletitled, Identification and Characterization of Signal Transducer and Activator of Transcription 3 Recruitment Sites within the Epidermal Growth Factor Receptor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

A Novel Telomerase Template Antagonist (GRN163) as a Potential Anticancer Agent 1

Akira Asai; Yuko Oshima; Yoshihiro Yamamoto; Taka-aki Uochi; Hideaki Kusaka; Shiro Akinaga; Yoshinori Yamashita; Krisztina Pongracz; Ronald Pruzan; Ellen Wunder; Mieczyslaw Piatyszek; Shihong Li; Allison C. Chin; Calvin B. Harley; Sergei Gryaznov

View articletitled, A Novel Telomerase Template Antagonist (GRN163) as a Potential Anticancer Agent<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Carcinogenesis

Gene Expression Profiling in Polycythemia Vera Using cDNA Microarray Technology 1

Andrea Pellagatti; David Vetrie; Cordelia F. Langford; Susana Gama; Helen Eagleton; James S. Wainscoat; Jacqueline Boultwood

View articletitled, Gene Expression Profiling in Polycythemia Vera Using cDNA Microarray Technology<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Antizyme Overexpression in Transgenic Mice Reduces Cell Proliferation, Increases Apoptosis, and Reduces N-Nitrosomethylbenzylamine-induced Forestomach Carcinogenesis 1

Louise Y. Y. Fong; David J. Feith; Anthony E. Pegg

View articletitled, Antizyme Overexpression in Transgenic Mice Reduces Cell Proliferation, Increases Apoptosis, and Reduces <em>N</em>-Nitrosomethylbenzylamine-induced Forestomach Carcinogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Clinical Investigations

Analysis of BRAF and N-RAS Mutations in Metastatic Melanoma Tissues 1

Alexis Gorden; Iman Osman; Weiming Gai; Dan He; Weiqing Huang; Anne Davidson; Alan N. Houghton; Klaus Busam; David Polsky

View articletitled, Analysis of <strong><em>BRAF</em></strong> and <strong><em>N-RAS</em></strong> Mutations in Metastatic Melanoma Tissues<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Human Kallikrein 5: A Potential Novel Serum Biomarker for Breast and Ovarian Cancer 1

George M. Yousef; Mary-Ellen Polymeris; Linda Grass; Antoninus Soosaipillai; Pak-Cheung Chan; Andreas Scorilas; Carla Borgoño; Nadia Harbeck; Barbara Schmalfeldt; Julia Dorn; Manfred Schmitt; Eleftherios P. Diamandis

View articletitled, Human Kallikrein 5<span class="subtitle-colon">: </span><span class="subtitle">A Potential Novel Serum Biomarker for Breast and Ovarian Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

Increased Plasma DNA Integrity in Cancer Patients 1

Brant G. Wang; Han-Yao Huang; Yu-Chi Chen; Robert E. Bristow; Keyanunoosh Kassauei; Chih-Chien Cheng; Richard Roden; Lori J. Sokoll; Daniel W. Chan; Ie-Ming Shih

View articletitled, Increased Plasma DNA Integrity in Cancer Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Expansion of Microvascular Bed and Increased Solute Flux in Human Basal Cell Carcinoma in Vivo, Measured by Fluorescein Video Angiography 1

Anthony W. B. Stanton; Simon B. Drysdale; Reena Patel; Russell H. Mellor; Michael J. B. Duff; J. Rodney Levick; Peter S. Mortimer

View articletitled, Expansion of Microvascular Bed and Increased Solute Flux in Human Basal Cell Carcinoma <strong><em>in Vivo</em></strong>, Measured by Fluorescein Video Angiography<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Epidemiology and Prevention

Urinary Isothiocyanate Levels, Brassica, and Human Breast Cancer 1

Jay H. Fowke; Fung-Lung Chung; Fan Jin; Dai Qi; Qiuyin Cai; Cliff Conaway; Jia-Rong Cheng; Xiao-Ou Shu; Yu-Tang Gao; Wei Zheng

View articletitled, Urinary Isothiocyanate Levels, Brassica, and Human Breast Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

A Functional Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter (−1306C/T) Is Associated with Risk of Development but not Metastasis of Gastric Cardia Adenocarcinoma 1

Xiaoping Miao; Chunyuan Yu; Wen Tan; Ping Xiong; Gang Liang; Wenfu Lu; Dongxin Lin

View articletitled, A Functional Polymorphism in the <strong><em>Matrix Metalloproteinase-2</em></strong> Gene Promoter (−1306C/T) Is Associated with Risk of Development but not Metastasis of Gastric Cardia Adenocarcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Serum Insulin-like Growth Factor I: Tumor Marker or Etiologic Factor? A Prospective Study of Prostate Cancer among Finnish Men 1

Karen Woodson; Joseph A. Tangrea; Michael Pollak; Terry D. Copeland; Philip R. Taylor; Jarmo Virtamo; Demetrius Albanes

View articletitled, Serum Insulin-like Growth Factor I<span class="subtitle-colon">: </span><span class="subtitle">Tumor Marker or Etiologic Factor? A Prospective Study of Prostate Cancer among Finnish Men<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

Experimental Therapeutics

Design, Expression, Purification, and Characterization, in Vitro and in Vivo, of an Antimelanoma Single-chain Fv Antibody Fused to the Toxin Gelonin 1

Michael G. Rosenblum; Lawrence H. Cheung; Yuying Liu; John W. Marks, III

View articletitled, Design, Expression, Purification, and Characterization, <strong><em>in Vitro</em></strong> and <strong><em>in Vivo</em></strong>, of an Antimelanoma Single-chain Fv Antibody Fused to the Toxin Gelonin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Pharmacologic Indicators of Antitumor Efficacy for Oncolytic Virotherapy

G. William Demers; Duane E. Johnson; Van Tsai; Shu-Fen Wen; Erlinda Quijano; Todd Machemer; Jennifer Philopena; Murali Ramachandra; John A. Howe; Paul Shabram; Robert Ralston; Heidrun Engler

View articletitled, Pharmacologic Indicators of Antitumor Efficacy for Oncolytic Virotherapy

Open the PDF for in another window

SU11248 Maintenance Therapy Prevents Tumor Regrowth after Fractionated Irradiation of Murine Tumor Models 1

Aaron J. Schueneman; Eric Himmelfarb; Ling Geng; Jiahua Tan; Edwin Donnelly; Dirk Mendel; Gerald McMahon; Dennis E. Hallahan

View articletitled, SU11248 Maintenance Therapy Prevents Tumor Regrowth after Fractionated Irradiation of Murine Tumor Models<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Efficient Therapeutic Gene Delivery after Systemic Administration of a Novel Polyethylenimine/DNA Vector in an Orthotopic Bladder Cancer Model 1

Paul Sweeney; Takashi Karashima; Hisashi Ishikura; Sandy Wiehle; Motoyuki Yamashita; William F. Benedict; Richard J. Cristiano; Colin P. N. Dinney

View articletitled, Efficient Therapeutic Gene Delivery after Systemic Administration of a Novel Polyethylenimine/DNA Vector in an Orthotopic Bladder Cancer Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Extreme Sensitivity of Adult Neurogenesis to Low Doses of X-Irradiation 1

Shinichiro Mizumatsu; Michelle L. Monje; Duncan R. Morhardt; Radoslaw Rola; Theo D. Palmer; John R. Fike

View articletitled, Extreme Sensitivity of Adult Neurogenesis to Low Doses of X-Irradiation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

A New Indole-3-Carbinol Tetrameric Derivative Inhibits Cyclin-dependent Kinase 6 Expression, and Induces G₁ Cell Cycle Arrest in Both Estrogen-dependent and Estrogen-independent Breast Cancer Cell Lines 1

Giorgio Brandi; Mirko Paiardini; Barbara Cervasi; Chiara Fiorucci; Paolino Filippone; Cinzia De Marco; Nadia Zaffaroni; Mauro Magnani

View articletitled, A New Indole-3-Carbinol Tetrameric Derivative Inhibits Cyclin-dependent Kinase 6 Expression, and Induces G<sub>1</sub> Cell Cycle Arrest in Both Estrogen-dependent and Estrogen-independent Breast Cancer Cell Lines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Inhibition of Cancer Cell Proliferation and Prostaglandin E₂ Synthesis by Scutellaria Baicalensis1

David Y. Zhang; Josephine Wu; Fei Ye; Li Xue; Shiquan Jiang; Jizu Yi; Wandi Zhang; Huachen Wei; Max Sung; Wayne Wang; Xiaoping Li

View articletitled, Inhibition of Cancer Cell Proliferation and Prostaglandin E<sub>2</sub> Synthesis by <strong><em>Scutellaria Baicalensis</em></strong><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Synergistic Augmentation of Antimicrotubule Agent-induced Cytotoxicity by a Phosphoinositide 3-Kinase Inhibitor in Human Malignant Glioma Cells

Takashi Shingu; Kazuo Yamada; Nobumasa Hara; Kouzo Moritake; Harumi Osago; Masaharu Terashima; Takeshi Uemura; Toshiki Yamasaki; Mikako Tsuchiya

View articletitled, Synergistic Augmentation of Antimicrotubule Agent-induced Cytotoxicity by a Phosphoinositide 3-Kinase Inhibitor in Human Malignant Glioma Cells

Open the PDF for in another window

Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-d-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate Transport 1

Zhe-Sheng Chen; Robert W. Robey; Martin G. Belinsky; Irina Shchaveleva; Xiao-Qin Ren; Yoshikazu Sugimoto; Douglas D. Ross; Susan E. Bates; Gary D. Kruh

View articletitled, Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-<span class="small-caps">d</span>-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate Transport<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Antiangiogenic Treatment with Thrombospondin-1 Enhances Primary Tumor Radiation Response and Prevents Growth of Dormant Pulmonary Micrometastases after Curative Radiation Therapy in Human Melanoma Xenografts 1

Einar K. Rofstad; Kristin Henriksen; Kanthi Galappathi; Berit Mathiesen

View articletitled, Antiangiogenic Treatment with Thrombospondin-1 Enhances Primary Tumor Radiation Response and Prevents Growth of Dormant Pulmonary Micrometastases after Curative Radiation Therapy in Human Melanoma Xenografts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

A New Approach for the Treatment of Malignant Melanoma: Enhanced Antitumor Efficacy of an Albumin-binding Doxorubicin Prodrug That Is Cleaved by Matrix Metalloproteinase 2 1

Ahmed M. Mansour; Joachim Drevs; Norbert Esser; Farid M. Hamada; Osama A. Badary; Clemens Unger; Iduna Fichtner; Felix Kratz

View articletitled, A New Approach for the Treatment of Malignant Melanoma: Enhanced Antitumor Efficacy of an Albumin-binding Doxorubicin Prodrug That Is Cleaved by Matrix Metalloproteinase 2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

A Novel Approach to Cancer Immunotherapy: Tumor Cells Decorated with CD80 Generate Effective Antitumor Immunity 1

Narendra P. Singh; Esma S. Yolcu; Douglas D. Taylor; Cicek Gercel-Taylor; Daniel S. Metzinger; Stephen K. Dreisbach; Haval Shirwan

View articletitled, A Novel Approach to Cancer Immunotherapy<span class="subtitle-colon">: </span><span class="subtitle">Tumor Cells Decorated with CD80 Generate Effective Antitumor Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

G₂ Arrest in Response to Topoisomerase II Inhibitors: The Role of p53 1

Brad Clifford; Milos Beljin; George R. Stark; William R. Taylor

View articletitled, G<sub>2</sub> Arrest in Response to Topoisomerase II Inhibitors<span class="subtitle-colon">: </span><span class="subtitle">The Role of p53<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

Radiochemical Investigations of Gastrin-releasing Peptide Receptor-specific [^99mTc(X)(CO)₃-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH₂)] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and in Vitro/in Vivo Studies where Dpr = 2,3-Diaminopropionic acid and X = H₂O or P(CH₂OH)₃ 1

C. Jeffrey Smith; Gary L. Sieckman; Nellie K. Owen; Donald L. Hayes; Dana G. Mazuru; Raghuraman Kannan; Wynn A. Volkert; Timothy J. Hoffman

View articletitled, Radiochemical Investigations of Gastrin-releasing Peptide Receptor-specific [<sup>99m</sup>Tc(X)(CO)<sub>3</sub>-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH<sub>2</sub>)] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and <strong><em>in Vitro</em></strong>/<strong><em>in Vivo</em></strong> Studies where Dpr = 2,3-Diaminopropionic acid and X = H<sub>2</sub>O or P(CH<sub>2</sub>OH)<sub>3</sub><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Specific Biochemical Inactivation of Oncogenic Ras Proteins by Nucleoside Diphosphate Kinase 1

Michael A. Fischbach; Jeffrey Settleman

View articletitled, Specific Biochemical Inactivation of Oncogenic Ras Proteins by Nucleoside Diphosphate Kinase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Immunology

A Critical Requirement of Interferon γ-mediated Angiostasis for Tumor Rejection by CD8⁺ T Cells 1

Zhihai Qin; Johannes Schwartzkopff; Felicia Pradera; Thomas Kammertœns; Barbara Seliger; Hanspeter Pircher; Thomas Blankenstein

View articletitled, A Critical Requirement of Interferon γ-mediated Angiostasis for Tumor Rejection by CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Polarization of Vα24⁺ Vβ11⁺ Natural Killer T Cells of Healthy Volunteers and Cancer Patients Using α-Galactosylceramide-loaded and Environmentally Instructed Dendritic Cells 1

Hans J. J. van der Vliet; Johan W. Molling; Nobusuke Nishi; Allan J. Masterson; Wendy Kölgen; Steven A. Porcelli; Alfons J. M. van den Eertwegh; B. Mary E. von Blomberg; Herbert M. Pinedo; Giuseppe Giaccone; Rik J. Scheper

View articletitled, Polarization of Vα24<sup>+</sup> Vβ11<sup>+</sup> Natural Killer T Cells of Healthy Volunteers and Cancer Patients Using α-Galactosylceramide-loaded and Environmentally Instructed Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Functional Role of Human Leukocyte Antigen-G Up-Regulation in Renal Cell Carcinoma 1

Jürgen Bukur; Vera Rebmann; Hans Grosse-Wilde; Hans Luboldt; Herbert Ruebben; Ingo Drexler; Gerd Sutter; Christoph Huber; Barbara Seliger

View articletitled, Functional Role of Human Leukocyte Antigen-G Up-Regulation in Renal Cell Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Dendritic Cells Stimulated with a Bacterial Product, OK-432, Efficiently Induce Cytotoxic T Lymphocytes Specific to Tumor Rejection Peptide 1

Saori Nakahara; Takuya Tsunoda; Toshiyuki Baba; Shinichi Asabe; Hideaki Tahara

View articletitled, Dendritic Cells Stimulated with a Bacterial Product, OK-432, Efficiently Induce Cytotoxic T Lymphocytes Specific to Tumor Rejection Peptide<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

The Antigen Processing Machinery of Class I Human Leukocyte Antigens: Linked Patterns of Gene Expression in Neoplastic Cells 1

Ezio Giorda; Leonardo Sibilio; Aline Martayan; Sara Moretti; Irene Venturo; Marcella Mottolese; Giovan Battista Ferrara; Sandra Cappellacci; Laura Eibenschutz; Caterina Catricalà; Paola Grammatico; Patrizio Giacomini

View articletitled, The Antigen Processing Machinery of Class I Human Leukocyte Antigens<span class="subtitle-colon">: </span><span class="subtitle">Linked Patterns of Gene Expression in Neoplastic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

CpG Oligodeoxynucleotides Enhance the Capacity of Adenovirus-mediated CD154 Gene Transfer to Generate Effective B-Cell Lymphoma Vaccines 1

Roman Rieger; Thomas J. Kipps

View articletitled, CpG Oligodeoxynucleotides Enhance the Capacity of Adenovirus-mediated CD154 Gene Transfer to Generate Effective B-Cell Lymphoma Vaccines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Molecular Biology and Genetics

Amplification and Overexpression of the Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 2 (DYRK2) Gene in Esophageal and Lung Adenocarcinomas 1

Charles T. Miller; Sanjeev Aggarwal; Theodore K. Lin; Susan L. Dagenais; Jorge I. Contreras; Mark B. Orringer; Thomas W. Glover; David G. Beer; Lin Lin

View articletitled, Amplification and Overexpression of the Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 2 (<strong><em>DYRK2</em></strong>) Gene in Esophageal and Lung Adenocarcinomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Identifying Tumor Origin Using a Gene Expression-based Classification Map 1

Phillip Buckhaults; Zhen Zhang; Yu-Chi Chen; Tian-Li Wang; Brad St. Croix; Saurabh Saha; Alberto Bardelli; Patrice J. Morin; Kornelia Polyak; Ralph H. Hruban; Victor E. Velculescu; Ie-Ming Shih

View articletitled, Identifying Tumor Origin Using a Gene Expression-based Classification Map<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

BAG-1 Prevents Stress-induced Long-term Growth Inhibition in Breast Cancer Cells via a Chaperone-dependent Pathway 1

Paul A. Townsend; Ramsey I. Cutress; Adam Sharp; Matthew Brimmell; Graham Packham

View articletitled, BAG-1 Prevents Stress-induced Long-term Growth Inhibition in Breast Cancer Cells via a Chaperone-dependent Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Frequent Hypomethylation of Multiple Genes Overexpressed in Pancreatic Ductal Adenocarcinoma 1

Norihiro Sato; Anirban Maitra; Noriyoshi Fukushima; N. Tjarda van Heek; Hiroyuki Matsubayashi; Christine A. Iacobuzio-Donahue; Christophe Rosty; Michael Goggins

View articletitled, Frequent Hypomethylation of Multiple Genes Overexpressed in Pancreatic Ductal Adenocarcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

UbcH10 Is the Cancer-related E2 Ubiquitin-conjugating Enzyme 1

Yoshiaki Okamoto; Toshinori Ozaki; Kou Miyazaki; Mineyoshi Aoyama; Masaru Miyazaki; Akira Nakagawara

View articletitled, UbcH10 Is the Cancer-related E2 Ubiquitin-conjugating Enzyme<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Aberrant Methylation and Silencing of ARHI, an Imprinted Tumor Suppressor Gene in which the Function Is Lost in Breast Cancers 1

Jiuhong Yuan; Robert Z. Luo; Satoshi Fujii; Lin Wang; Wei Hu; Michael Andreeff; Yong Pan; Mitsutaka Kadota; Mitsuo Oshimura; Aysegul A. Sahin; Jean-Pierre Issa; Robert C. Bast, Jr.; Yinhua Yu

View articletitled, Aberrant Methylation and Silencing of <strong><em>ARHI</em></strong>, an Imprinted Tumor Suppressor Gene in which the Function Is Lost in Breast Cancers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Tumor Necrosis Factor α Induces Angiogenic Factor Up-Regulation in Malignant Glioma Cells: A Role for RNA Stabilization and HuR 1

L. Burt Nabors; Esther Suswam; Yuanyuan Huang; Xiuhua Yang; Martin J. Johnson; Peter H. King

View articletitled, Tumor Necrosis Factor α Induces Angiogenic Factor Up-Regulation in Malignant Glioma Cells<span class="subtitle-colon">: </span><span class="subtitle">A Role for RNA Stabilization and HuR<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

rgr Oncogene: Activation by Elimination of Translational Controls and Mislocalization 1

Inmaculada Hernández-Muñoz; Marta Benet; Miguel Calero; Maria Jiménez; Roberto Díaz; Angel Pellicer

View articletitled, <strong><em>rgr</em></strong> Oncogene<span class="subtitle-colon">: </span><span class="subtitle">Activation by Elimination of Translational Controls and Mislocalization<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>

Open the PDF for in another window

Tumor Biology

Survival Analysis of Genome-Wide Gene Expression Profiles of Prostate Cancers Identifies New Prognostic Targets of Disease Relapse 1^,2

Susan M. Henshall; Daniel E. H. Afar; Jordan Hiller; Lisa G. Horvath; David I. Quinn; Krishan K. Rasiah; Kurt Gish; Dorian Willhite; James G. Kench; Margaret Gardiner-Garden; Phillip D. Stricker; Howard I. Scher; John J. Grygiel; David B. Agus; David H. Mack; Robert L. Sutherland

View articletitled, Survival Analysis of Genome-Wide Gene Expression Profiles of Prostate Cancers Identifies New Prognostic Targets of Disease Relapse<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup><sup><a href="javascript:;" reveal-id="FN3" data-open="FN3" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">,2</a></sup>

Open the PDF for in another window

Menin Associates with FANCD2, a Protein Involved in Repair of DNA Damage 1

Shenghao Jin; Hua Mao; Robert W. Schnepp; Stephen M. Sykes; Albert C. Silva; Alan D. D’Andrea; Xianxin Hua

View articletitled, Menin Associates with FANCD2, a Protein Involved in Repair of DNA Damage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Molecular Phenotype of Spontaneously Arising 4N (G₂-Tetraploid) Intermediates of Neoplastic Progression in Barrett’s Esophagus 1

Michael T. Barrett; David Pritchard; Corinna Palanca-Wessels; Judy Anderson; Brian J. Reid; Peter S. Rabinovitch

View articletitled, Molecular Phenotype of Spontaneously Arising 4N (G<sub>2</sub>-Tetraploid) Intermediates of Neoplastic Progression in Barrett’s Esophagus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Differential Expression of Folate Receptor in Pituitary Adenomas 1

Chheng-Orn Evans; Prasad Reddy; Daniel J. Brat; Eric B. O’Neill; Branch Craige; Victoria L. Stevens; Nelson M. Oyesiku

View articletitled, Differential Expression of Folate Receptor in Pituitary Adenomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

The Oncogene Phosphatidylinositol 3′-Kinase Catalytic Subunit α Promotes Angiogenesis via Vascular Endothelial Growth Factor in Ovarian Carcinoma 1

Lin Zhang; Nuo Yang; Dionyssios Katsaros; Wei Huang; Jin-Wan Park; Stefano Fracchioli; Cristina Vezzani; Irene A. Rigault de la Longrais; Weijia Yao; Stephen C. Rubin; George Coukos

View articletitled, The Oncogene Phosphatidylinositol 3′-Kinase Catalytic Subunit α Promotes Angiogenesis via Vascular Endothelial Growth Factor in Ovarian Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Deficiency of Kinase Suppressor of Ras1 Prevents Oncogenic Ras Signaling in Mice 1

José Lozano; Rosie Xing; Zhenzi Cai; Heather L. Jensen; Carol Trempus; Willie Mark; Ron Cannon; Richard Kolesnick

View articletitled, Deficiency of Kinase Suppressor of Ras1 Prevents Oncogenic Ras Signaling in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Viable Circulating Metastatic Cells Produced in Orthotopic but not Ectopic Prostate Cancer Models 1

Anna B. Glinskii; Brian A. Smith; Ping Jiang; Xiao-Ming Li; Meng Yang; Robert M. Hoffman; Gennadi V. Glinsky

View articletitled, Viable Circulating Metastatic Cells Produced in Orthotopic but not Ectopic Prostate Cancer Models<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Combined Cyclin D1 Overexpression and Zinc Deficiency Disrupts Cell Cycle and Accelerates Mouse Forestomach Carcinogenesis 1

Louise Y. Y. Fong; Rita Mancini; Hiroshi Nakagawa; Anil K. Rustgi; Kay Huebner

View articletitled, Combined Cyclin D1 Overexpression and Zinc Deficiency Disrupts Cell Cycle and Accelerates Mouse Forestomach Carcinogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Heavy Ion Irradiation Inhibits in Vitro Angiogenesis Even at Sublethal Dose 1

Yutaka Takahashi; Teruki Teshima; Naomasa Kawaguchi; Yoshinosuke Hamada; Seiji Mori; Ayako Madachi; Satoko Ikeda; Hirokazu Mizuno; Toshiyuki Ogata; Kumie Nojima; Yoshiya Furusawa; Nariaki Matsuura

View articletitled, Heavy Ion Irradiation Inhibits <strong><em>in Vitro</em></strong> Angiogenesis Even at Sublethal Dose<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Overexpression of Platelet-type 12-Lipoxygenase Promotes Tumor Cell Survival by Enhancing α_vβ₃ and α_vβ₅ Integrin Expression 1

Graham P. Pidgeon; Keqin Tang; Yin Long Cai; Evano Piasentin; Kenneth V. Honn

View articletitled, Overexpression of Platelet-type 12-Lipoxygenase Promotes Tumor Cell Survival by Enhancing α<sub>v</sub>β<sub>3</sub> and α<sub>v</sub>β<sub>5</sub> Integrin Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Functional Analysis of the EWS/ETS Target Gene Uridine Phosphorylase 1

Benjamin Deneen; Habib Hamidi; Christopher T. Denny

View articletitled, Functional Analysis of the EWS/ETS Target Gene Uridine Phosphorylase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>

Open the PDF for in another window

Angiostatin_4.5-mediated Apoptosis of Vascular Endothelial Cells

Holly Anne Hanford; Christie A. Wong; Hallie Kassan; Deborah L. Cundiff; Navdeep Chandel; Suzanne Underwood; Christopher A. Mitchell; Gerald A. Soff

View articletitled, Angiostatin<sub>4.5</sub>-mediated Apoptosis of Vascular Endothelial Cells

Open the PDF for in another window

Luteinizing Hormone Increases Human Endometrial Cancer Cells Invasiveness through Activation of Protein Kinase A

Sara Dabizzi; Ivo Noci; Patrizia Borri; Elena Borrani; Massimo Giachi; Manuela Balzi; Gian Luigi Taddei; Mauro Marchionni; Gian Franco Scarselli; Annarosa Arcangeli

View articletitled, Luteinizing Hormone Increases Human Endometrial Cancer Cells Invasiveness through Activation of Protein Kinase A

Open the PDF for in another window

Cell Proliferation in Liver of Mmh/Ogg1-deficient Mice Enhances Mutation Frequency because of the Presence of 8-Hydroxyguanine in DNA

Tsuyoshi Arai; Vincent P. Kelly; Kimiyo Komoro; Osamu Minowa; Tetsuo Noda; Susumu Nishimura

View articletitled, Cell Proliferation in Liver of <strong><em>Mmh/Ogg1</em></strong>-deficient Mice Enhances Mutation Frequency because of the Presence of 8-Hydroxyguanine in DNA

Open the PDF for in another window

Advertisement

Email alerts

eTOC Alert

Latest
Most Read
Most Cited

Hypoxic bone marrow stromal cells secrete miR-140-5p and miR-28-3p target SPRED1 to confer drug resistance in multiple myeloma

Super enhancer-regulated lncRNA LINC01089 induces alternative splicing of DIAPH3 to drive hepatocellular carcinoma metastasis

Epigenetic regulators open the door to SCLC plasticity

Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells

Issues
Online First
Collections

News
Twitter

Online ISSN 1538-7445
Print ISSN 0008-5472

AACR Journals

Blood Cancer Discovery
Cancer Discovery
Cancer Epidemiology, Biomarkers & Prevention
Cancer Immunology Research
Cancer Prevention Research
Cancer Research
Cancer Research Communications
Clinical Cancer Research
Molecular Cancer Research
Molecular Cancer Therapeutics

Info for Advertisers
Information for Institutions/Librarians
Privacy Policy

Twitter
LinkedIn
Facebook
Youtube

Copyright © 2023 by the American Association for Cancer Research.

This Feature Is Available To Subscribers Only

Sign In or Create an Account

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.

Accept