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Issues

Volume 63, Issue 12
15 June 2003
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Review

10 Years of Mouse Cancer Modifier Loci: Human Relevance1
Tommaso A. Dragani
View articletitled, 10 Years of Mouse Cancer Modifier Loci<span class="subtitle-colon">: </span><span class="subtitle">Human Relevance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Advances in Brief

Delayed in Vivo Disease Progression Is Associated with High Proportions of CD45+ Myeloma Cells in the 5T2MM Murine Model1
Kewal Asosingh; Angelo Willems; Ivan Van Riet; Benjamin Van Camp; Karin Vanderkerken
View articletitled, Delayed <strong><em>in Vivo</em></strong> Disease Progression Is Associated with High Proportions of CD45<sup>+</sup> Myeloma Cells in the 5T2MM Murine Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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p21Cip1 Nullizygosity Increases Tumor Metastasis in Irradiated Mice1
Rosalind J. Jackson; Robert W. Engelman; Domenico Coppola; Alan B. Cantor; Walker Wharton; W. Jack Pledger
View articletitled, p21<sup>Cip1</sup> Nullizygosity Increases Tumor Metastasis in Irradiated Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Lytic Bone Lesions in Human Neuroblastoma Xenograft Involve Osteoclast Recruitment and Are Inhibited by Bisphosphonate1
Yasuyoshi Sohara; Hiroyuki Shimada; Miriam Scadeng; Harvey Pollack; Shinya Yamada; Wei Ye; C. Patrick Reynolds; Yves A. DeClerck
View articletitled, Lytic Bone Lesions in Human Neuroblastoma Xenograft Involve Osteoclast Recruitment and Are Inhibited by Bisphosphonate<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cyclooxygenase-2 Expression and Effect of Celecoxib in Gastric Adenomas of Trefoil Factor 1-deficient Mice1
Kirsi Saukkonen; Catherine Tomasetto; Kirsi Narko; Marie-Christine Rio; Ari Ristimäki
View articletitled, Cyclooxygenase-2 Expression and Effect of Celecoxib in Gastric Adenomas of Trefoil Factor 1-deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Inhibition of the Development of Metastatic Squamous Cell Carcinoma in Protein Kinase C ε Transgenic Mice by α-Difluoromethylornithine Accompanied by Marked Hair Follicle Degeneration and Hair Loss
Deric L. Wheeler; Kristin J. Ness; Terry D. Oberley; Ajit K. Verma
View articletitled, Inhibition of the Development of Metastatic Squamous Cell Carcinoma in Protein Kinase C ε Transgenic Mice by α-Difluoromethylornithine Accompanied by Marked Hair Follicle Degeneration and Hair Loss
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Involvement of PEG10 in Human Hepatocellular Carcinogenesis through Interaction with SIAH11
Hiroshi Okabe; Seiji Satoh; Yoichi Furukawa; Tatsushi Kato; Suguru Hasegawa; Yumi Nakajima; Yoshio Yamaoka; Yusuke Nakamura
View articletitled, Involvement of PEG10 in Human Hepatocellular Carcinogenesis through Interaction with SIAH1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Both DNA Topoisomerase II-binding Protein 1 and BRCA1 Regulate the G2-M Cell Cycle Checkpoint1
Kazuhiko Yamane; Junjie Chen; Timothy J. Kinsella
View articletitled, Both DNA Topoisomerase II-binding Protein 1 and BRCA1 Regulate the G<sub>2</sub>-M Cell Cycle Checkpoint<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Suppression of Bcl-xL Deamidation in Human Hepatocellular Carcinomas1
Tetsuo Takehara; Hiroshi Takahashi
View articletitled, Suppression of Bcl-xL Deamidation in Human Hepatocellular Carcinomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Inhibition of Early Tumor Growth Requires Jα18-positive (Natural Killer T) Cells1
Trina J. Stewart; Mark J. Smyth; Germain J. P. Fernando; Ian H. Frazer; Graham R. Leggatt
View articletitled, Inhibition of Early Tumor Growth Requires Jα18-positive (Natural Killer T) Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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BRAF as a Melanoma Susceptibility Candidate Gene?1
Karine Laud; Caroline Kannengiesser; Marie-Francoise Avril; Agnès Chompret; Dominique Stoppa-Lyonnet; Laurence Desjardins; Alain Eychene; Florence Demenais; French Hereditary Melanoma Study Group; Gilbert M. Lenoir; Brigitte Bressac-de Paillerets
View articletitled, <strong><em>BRAF</em></strong> as a Melanoma Susceptibility Candidate Gene?<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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An Interleukin-6 Gene Promoter Polymorphism Influences the Biological Phenotype of Ovarian Cancer
Lukas A. Hefler; Christoph Grimm; Sven Ackermann; Sabine Malur; Amir R. Radjabi-Rahat; Sepp Leodolter; Matthias W. Beckmann; Robert Zeillinger; Heinz Koelbl; Clemens B. Tempfer
View articletitled, An Interleukin-6 Gene Promoter Polymorphism Influences the Biological Phenotype of Ovarian Cancer
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Histone Deacetylase Inhibitor Up-Regulates RECK to Inhibit MMP-2 Activation and Cancer Cell Invasion1
Li-Teh Liu; Hui-Chiu Chang; Lien-Chai Chiang; Wen-Chun Hung
View articletitled, Histone Deacetylase Inhibitor Up-Regulates RECK to Inhibit MMP-2 Activation and Cancer Cell Invasion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Adenovirus with Insertion-mutated E1A Selectively Propagates in Liver Cancer Cells and Destroys Tumors in Vivo1
Tiejun Zhao; Xiao-Mei Rao; Xiaoming Xie; Ling Li; Timothy C. Thompson; Kelly M. McMasters; Heshan Sam Zhou
View articletitled, Adenovirus with Insertion-mutated E1A Selectively Propagates in Liver Cancer Cells and Destroys Tumors <strong><em>in Vivo</em></strong><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Biochemistry and Biophysics

NUP98 Is Fused to Adducin 3 in a Patient with T-Cell Acute Lymphoblastic Leukemia and Myeloid Markers, with a New Translocation t(10;11)(q25;p15)1
Idoya Lahortiga; José L. Vizmanos; Xabier Agirre; Iria Vázquez; Juan C. Cigudosa; María J. Larrayoz; Francisco Sala; Ana Gorosquieta; Katy Perez-Equiza; María J. Calasanz; María D. Odero
View articletitled, <strong><em>NUP98</em></strong> Is Fused to <strong><em>Adducin 3</em></strong> in a Patient with T-Cell Acute Lymphoblastic Leukemia and Myeloid Markers, with a New Translocation t(10;11)(q25;p15)<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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P-Glycoprotein, Expressed in Multidrug Resistant Cells, Is Not Responsible for Alterations in Membrane Fluidity or Membrane Potential1
Claudina Alemán; Jean-Philippe Annereau; Xing-Jie Liang; Carol O. Cardarelli; Barbara Taylor; Jun Jie Yin; Adorjan Aszalos; Michael M. Gottesman
View articletitled, P-Glycoprotein, Expressed in Multidrug Resistant Cells, Is Not Responsible for Alterations in Membrane Fluidity or Membrane Potential<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Carcinogenesis

Class I Alcohol Dehydrogenase Is Highly Expressed in Normal Human Mammary Epithelium but not in Invasive Breast Cancer: Implications for Breast Carcinogenesis1
Elise A. Triano; Leslie B. Slusher; Trudy A. Atkins; John T. Beneski; Shelley A. Gestl; Reza Zolfaghari; Rathnagiri Polavarapu; Elizabeth Frauenhoffer; Judith Weisz
View articletitled, Class I Alcohol Dehydrogenase Is Highly Expressed in Normal Human Mammary Epithelium but not in Invasive Breast Cancer<span class="subtitle-colon">: </span><span class="subtitle">Implications for Breast Carcinogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Multiple Promoters of Catechol-O-methyltransferase Gene Are Selectively Inactivated by CpG Hypermethylation in Endometrial Cancer
Masahiro Sasaki; Masanori Kaneuchi; Noriaki Sakuragi; Rajvir Dahiya
View articletitled, Multiple Promoters of <strong><em>Catechol-O-methyltransferase</em></strong> Gene Are Selectively Inactivated by CpG Hypermethylation in Endometrial Cancer
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Persistent Oxidative Stress in Chromosomally Unstable Cells1
Charles L. Limoli; Erich Giedzinski; William F. Morgan; Steven G. Swarts; George D. D. Jones; William Hyun
View articletitled, Persistent Oxidative Stress in Chromosomally Unstable Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Glucocorticoid Cotreatment Induces Apoptosis Resistance toward Cancer Therapy in Carcinomas1
Ingrid Herr; Esat Ucur; Kerstin Herzer; Stella Okouoyo; Rüdiger Ridder; Peter H. Krammer; Magnus von Knebel Doeberitz; Klaus-Michael Debatin
View articletitled, Glucocorticoid Cotreatment Induces Apoptosis Resistance toward Cancer Therapy in Carcinomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Clinical Investigations

Quantitative Correlation of Serum Levels and Tumor Expression of Vascular Endothelial Growth Factor in Patients with Hepatocellular Carcinoma
Ronnie Tung-Ping Poon; Cecilia Pik-Yuk Lau; Siu-Tim Cheung; Wun-Ching Yu; Sheung-Tat Fan
View articletitled, Quantitative Correlation of Serum Levels and Tumor Expression of Vascular Endothelial Growth Factor in Patients with Hepatocellular Carcinoma
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Endocrinology

Methoxyestrogens Exert Feedback Inhibition on Cytochrome P450 1A1 and 1B11
Sheila Dawling; Nady Roodi; Fritz F. Parl
View articletitled, Methoxyestrogens Exert Feedback Inhibition on Cytochrome P450 1A1 and 1B1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Epidemiology and Prevention

Effects of Dietary Folate and Alcohol Intake on Promoter Methylation in Sporadic Colorectal Cancer: The Netherlands Cohort Study on Diet and Cancer1
Manon van Engeland; Matty P. Weijenberg; Guido M. J. M. Roemen; Mirian Brink; Adriaan P. de Bruïne; R. Alexandra Goldbohm; Piet A. van den Brandt; Stephen B. Baylin; Anton F. P. M. de Goeij; James G. Herman
View articletitled, Effects of Dietary Folate and Alcohol Intake on Promoter Methylation in Sporadic Colorectal Cancer: The Netherlands Cohort Study on Diet and Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Lycopene Supplementation Inhibits Lung Squamous Metaplasia and Induces Apoptosis via Up-Regulating Insulin-like Growth Factor-binding Protein 3 in Cigarette Smoke-exposed Ferrets1
Chun Liu; Fuzhi Lian; Donald E. Smith; Robert M. Russell; Xiang-Dong Wang
View articletitled, Lycopene Supplementation Inhibits Lung Squamous Metaplasia and Induces Apoptosis via Up-Regulating Insulin-like Growth Factor-binding Protein 3 in Cigarette Smoke-exposed Ferrets<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Therapeutics

β-Catenin Regulates Vascular Endothelial Growth Factor Expression in Colon Cancer
Vijay Easwaran; Sang H. Lee; Landon Inge; Lida Guo; Cheryl Goldbeck; Evelyn Garrett; Marion Wiesmann; Pablo D. Garcia; John H. Fuller; Vivien Chan; Filippo Randazzo; Robert Gundel; Robert S. Warren; Jaime Escobedo; Sharon L. Aukerman; Robert N. Taylor; Wendy J. Fantl
View articletitled, β-Catenin Regulates Vascular Endothelial Growth Factor Expression in Colon Cancer
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Epidermal Growth Factor Receptor (EGFR)-targeted Immunoliposomes Mediate Specific and Efficient Drug Delivery to EGFR- and EGFRvIII-overexpressing Tumor Cells1
Christoph Mamot; Daryl C. Drummond; Udo Greiser; Keelung Hong; Dmitri B. Kirpotin; James D. Marks; John W. Park
View articletitled, Epidermal Growth Factor Receptor (EGFR)-targeted Immunoliposomes Mediate Specific and Efficient Drug Delivery to EGFR- and EGFRvIII-overexpressing Tumor Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Reovirus Prolongs Survival and Reduces the Frequency of Spinal and Leptomeningeal Metastases from Medulloblastoma1
Wen Qing Yang; Donna Senger; Huong Muzik; Zhong Qiao Shi; Denise Johnson; Penny M. A. Brasher; N. Barry Rewcastle; Mark Hamilton; Jim Rutka; Johannes Wolff; Cynthia Wetmore; Tom Curran; Patrick W. K. Lee; Peter A. Forsyth
View articletitled, Reovirus Prolongs Survival and Reduces the Frequency of Spinal and Leptomeningeal Metastases from Medulloblastoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Pharmacologically Regulated Production of Targeted Retrovirus from T Cells for Systemic Antitumor Gene Therapy1
Marka Crittenden; Michael Gough; John Chester; Tim Kottke; Jill Thompson; Anja Ruchatz; Tim Clackson; Francois Luic Cosset; Heung Chong; Rosa Maria Diaz; Kevin Harrington; Luis Alvarez Vallina; Richard Vile
View articletitled, Pharmacologically Regulated Production of Targeted Retrovirus from T Cells for Systemic Antitumor Gene Therapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Telomerase-dependent Conditionally Replicating Adenovirus for Selective Treatment of Cancer1
Thomas Wirth; Lars Zender; Bernd Schulte; Bettina Mundt; Ruben Plentz; Karl Lenhard Rudolph; Michael Manns; Stefan Kubicka; Florian Kühnel
View articletitled, A Telomerase-dependent Conditionally Replicating Adenovirus for Selective Treatment of Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Antiangiogenic Activity of N-substituted and Tetrafluorinated Thalidomide Analogues
Sylvia S. W. Ng; Michael Gütschow; Michael Weiss; Sunna Hauschildt; Uwe Teubert; Thomas K. Hecker; Frederick A. Luzzio; Erwin A. Kruger; Kurt Eger; William D. Figg
View articletitled, Antiangiogenic Activity of N-substituted and Tetrafluorinated Thalidomide Analogues
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Assignment of 1H Nuclear Magnetic Resonance Visible Polyunsaturated Fatty Acids in BT4C Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy-induced Programmed Cell Death1
Julian L. Griffin; Kimmo K. Lehtimäki; Piia K. Valonen; Olli H. J. Gröhn; Mikko I. Kettunen; Seppo Ylä-Herttuala; Asla Pitkänen; Jeremy K. Nicholson; Risto A. Kauppinen
View articletitled, Assignment of <sup>1</sup>H Nuclear Magnetic Resonance Visible Polyunsaturated Fatty Acids in BT4C Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy-induced Programmed Cell Death<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Synergistic Therapeutic Effects of a Tumor Targeting Antibody Fragment, Fused to Interleukin 12 and to Tumor Necrosis Factor α1
Cornelia Halin; Verena Gafner; Maria Elena Villani; Laura Borsi; Alexander Berndt; Hartwig Kosmehl; Luciano Zardi; Dario Neri
View articletitled, Synergistic Therapeutic Effects of a Tumor Targeting Antibody Fragment, Fused to Interleukin 12 and to Tumor Necrosis Factor α<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Taccalonolides E and A: Plant-derived Steroids with Microtubule-stabilizing Activity1
Tina L. Tinley; Deborah A. Randall-Hlubek; Rachel M. Leal; Evelyn M. Jackson; James W. Cessac; James C. Quada, Jr.; Thomas K. Hemscheidt; Susan L. Mooberry
View articletitled, Taccalonolides E and A<span class="subtitle-colon">: </span><span class="subtitle">Plant-derived Steroids with Microtubule-stabilizing Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Synchrotron Photoactivation of Cisplatin Elicits an Extra Number of DNA Breaks That Stimulate RAD51-mediated Repair Pathways1
Stéphanie Corde; Jacques Balosso; Hélène Elleaume; Michel Renier; Aurélie Joubert; Marie-Claude Biston; Jean-François Adam; Anne-Marie Charvet; Thierry Brochard; Jean-François Le Bas; François Estève; Nicolas Foray
View articletitled, Synchrotron Photoactivation of Cisplatin Elicits an Extra Number of DNA Breaks That Stimulate RAD51-mediated Repair Pathways<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Differential Effects of the Breast Cancer Resistance Protein on the Cellular Accumulation and Cytotoxicity of 9-Aminocamptothecin and 9-Nitrocamptothecin1
Rajeev Rajendra; Murugesan K. Gounder; Ahamed Saleem; Jan H. M. Schellens; Douglas D. Ross; Susan E. Bates; Patrick Sinko; Eric H. Rubin
View articletitled, Differential Effects of the Breast Cancer Resistance Protein on the Cellular Accumulation and Cytotoxicity of 9-Aminocamptothecin and 9-Nitrocamptothecin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Interleukin-6 Fused to an Anti-idiotype Antibody in a Vaccine Increases the Specific Humoral Immune Response against CA125+ (MUC-16) Ovarian Cancer1
Silke Reinartz; Andreas Hombach; Siegmund Köhler; Harald Schlebusch; Diethelm Wallwiener; Hinrich Abken; Uwe Wagner
View articletitled, Interleukin-6 Fused to an Anti-idiotype Antibody in a Vaccine Increases the Specific Humoral Immune Response against CA125<sup>+</sup> (MUC-16) Ovarian Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Geldanamycin and its 17-Allylamino-17-Demethoxy Analogue Antagonize the Action of Cisplatin in Human Colon Adenocarcinoma Cells: Differential Caspase Activation as a Basis for Interaction1
Irina A. Vasilevskaya; Tatiana V. Rakitina; Peter J. O’Dwyer
View articletitled, Geldanamycin and its 17-Allylamino-17-Demethoxy Analogue Antagonize the Action of Cisplatin in Human Colon Adenocarcinoma Cells<span class="subtitle-colon">: </span><span class="subtitle">Differential Caspase Activation as a Basis for Interaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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The Different Biological Effects of Telomestatin and TMPyP4 Can Be Attributed to Their Selectivity for Interaction with Intramolecular or Intermolecular G-Quadruplex Structures
Mu-Yong Kim; Mary Gleason-Guzman; Elzbieta Izbicka; David Nishioka; Laurence H. Hurley
View articletitled, The Different Biological Effects of Telomestatin and TMPyP4 Can Be Attributed to Their Selectivity for Interaction with Intramolecular or Intermolecular G-Quadruplex Structures
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Specific Tumoricidal Activity of a Secreted Proapoptotic Protein Consisting of HER2 Antibody and Constitutively Active Caspase-31
Lin-Tao Jia; Li-Hong Zhang; Cui-Juan Yu; Jing Zhao; Yan-Ming Xu; Jun-Hao Gui; Ming Jin; Zong-Ling Ji; Wei-Hong Wen; Cheng-Ji Wang; Si-Yi Chen; An-Gang Yang
View articletitled, Specific Tumoricidal Activity of a Secreted Proapoptotic Protein Consisting of HER2 Antibody and Constitutively Active Caspase-3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Flavopiridol, a Cyclin-dependent Kinase Inhibitor, Enhances Radiosensitivity of Ovarian Carcinoma Cells1
Uma Raju; Eiko Nakata; Kathy A. Mason; K. Kian Ang; Luka Milas
View articletitled, Flavopiridol, a Cyclin-dependent Kinase Inhibitor, Enhances Radiosensitivity of Ovarian Carcinoma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Adenovirus-mediated Heat-activated Antisense Ku70 Expression Radiosensitizes Tumor Cells in Vitro and in Vivo1
Gloria C. Li; Fuqui He; Xiyun Shao; Muneysau Urano; Lingbo Shen; Dooha Kim; Michael Borrelli; Steven A. Leibel; Philip H. Gutin; C. Clifton Ling
View articletitled, Adenovirus-mediated Heat-activated Antisense Ku70 Expression Radiosensitizes Tumor Cells <strong><em>in Vitro</em></strong> and <strong><em>in Vivo</em></strong><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Immunology

Antigen-driven Clonal Proliferation, Somatic Hypermutation, and Selection of B Lymphocytes Infiltrating Human Ductal Breast Carcinomas1
Sazini Nzula; James J. Going; David I. Stott
View articletitled, Antigen-driven Clonal Proliferation, Somatic Hypermutation, and Selection of B Lymphocytes Infiltrating Human Ductal Breast Carcinomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Generation of Antitumor Immunity by Cytotoxic T Lymphocyte Epitope Peptide Vaccination, CpG-oligodeoxynucleotide Adjuvant, and CTLA-4 Blockade1
Eduardo Davila; Richard Kennedy; Esteban Celis
View articletitled, Generation of Antitumor Immunity by Cytotoxic T Lymphocyte Epitope Peptide Vaccination, CpG-oligodeoxynucleotide Adjuvant, and CTLA-4 Blockade<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Molecular Biology and Genetics

The G2-phase Decatenation Checkpoint Is Defective in Werner Syndrome Cells1, 2
Annapaola Franchitto; Junko Oshima; Pietro Pichierri
View articletitled, The G<sub>2</sub>-phase Decatenation Checkpoint Is Defective in Werner Syndrome Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">, 2</a></sup>
Supplementary data
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Expression Profiling Identifies a Novel α-Methylacyl-CoA Racemase Exon with Fumarate Hydratase Homology1
Grace L. Shen-Ong; Yun Feng; Dean A. Troyer
View articletitled, Expression Profiling Identifies a Novel α-Methylacyl-CoA Racemase Exon with Fumarate Hydratase Homology<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
Supplementary data
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A Yeast Two-Hybrid Assay Provides a Simple Way to Evaluate the Vast Majority of hMLH1 Germ-Line Mutations1
Emiko Kondo; Hideyuki Suzuki; Akira Horii; Shinichi Fukushige
View articletitled, A Yeast Two-Hybrid Assay Provides a Simple Way to Evaluate the Vast Majority of <strong><em>hMLH1</em></strong> Germ-Line Mutations<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Combined Comparative Genomic Hybridization and Expression Microarray Analysis of Gastric Cancer Reveals Novel Molecular Subtypes1,2
Su Ting Tay; Siew Hong Leong; Kun Yu; Amit Aggarwal; Soo Yong Tan; Chee How Lee; Keith Wong; Jaya Visvanathan; Dennis Lim; Wai Keong Wong; Khee Chee Soo; Oi Lian Kon; Patrick Tan
View articletitled, A Combined Comparative Genomic Hybridization and Expression Microarray Analysis of Gastric Cancer Reveals Novel Molecular Subtypes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">,2</a></sup>
Supplementary data
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Fine Mapping and Identification of Candidate Pulmonary Adenoma Susceptibility 1 Genes Using Advanced Intercross Lines1
Min Wang; William J. Lemon; Gongjie Liu; Yian Wang; Fuad A. Iraqi; Alvin M. Malkinson; Ming You
View articletitled, Fine Mapping and Identification of Candidate Pulmonary Adenoma Susceptibility 1 Genes Using Advanced Intercross Lines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Contributions of ATM Mutations to Familial Breast and Ovarian Cancer1
Yvonne R. Thorstenson; Adriane Roxas; Regina Kroiss; Mark A. Jenkins; Kristine M. Yu; Thomas Bachrich; Daniela Muhr; Tierney L. Wayne; Gilbert Chu; Ronald W. Davis; Teresa M. U. Wagner; Peter J. Oefner
View articletitled, Contributions of <strong><em>ATM</em></strong> Mutations to Familial Breast and Ovarian Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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MSH2-deficient Human Cells Exhibit a Defect in the Accurate Termination of Homology-directed Repair of DNA Double-Strand Breaks1
Josée-France Villemure; Christine Abaji; Isabelle Cousineau; Abdellah Belmaaza
View articletitled, MSH2-deficient Human Cells Exhibit a Defect in the Accurate Termination of Homology-directed Repair of DNA Double-Strand Breaks<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Transforming Growth Factor β1 Increases the Stability of p21/WAF1/CIP1 Protein and Inhibits CDK2 Kinase Activity in Human Colon Carcinoma FET Cells1
JianGen Gong; Sudhakar Ammanamanchi; Tien C. Ko; Michael G. Brattain
View articletitled, Transforming Growth Factor β1 Increases the Stability of p21/WAF1/CIP1 Protein and Inhibits CDK2 Kinase Activity in Human Colon Carcinoma FET Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Role of Glutathione Peroxidase 1 in Breast Cancer: Loss of Heterozygosity and Allelic Differences in the Response to Selenium1
Ya Jun Hu; Alan M. Diamond
View articletitled, Role of Glutathione Peroxidase 1 in Breast Cancer<span class="subtitle-colon">: </span><span class="subtitle">Loss of Heterozygosity and Allelic Differences in the Response to Selenium<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Allelic Loss on Chromosome 3p21.3 and Promoter Hypermethylation of Semaphorin 3B in Non-Small Cell Lung Cancer1
Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Noel N. Williams; Larry R. Kaiser; Carlo M. Croce
View articletitled, Allelic Loss on Chromosome 3p21.3 and Promoter Hypermethylation of <strong><em>Semaphorin 3B</em></strong> in Non-Small Cell Lung Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Biology

The Ste20 Kinase MST4 Plays a Role in Prostate Cancer Progression
Victoria Sung; Wen Luo; Dapeng Qian; Isabelle Lee; Bahija Jallal; Mikhail Gishizky
View articletitled, The Ste20 Kinase MST4 Plays a Role in Prostate Cancer Progression
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Testican 2 Abrogates Inhibition of Membrane-type Matrix Metalloproteinases by Other Testican Family Proteins1
Mitsutoshi Nakada; Hisashi Miyamori; Junkoh Yamashita; Hiroshi Sato
View articletitled, Testican 2 Abrogates Inhibition of Membrane-type Matrix Metalloproteinases by Other Testican Family Proteins<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Angiopoietin-1 Inhibits Vascular Permeability, Angiogenesis, and Growth of Hepatic Colon Cancer Tumors1
Oliver Stoeltzing; Syed A. Ahmad; Wenbiao Liu; Marya F. McCarty; Jane S. Wey; Alexander A. Parikh; Fan Fan; Niels Reinmuth; Michiya Kawaguchi; Corazon D. Bucana; Lee M. Ellis
View articletitled, Angiopoietin-1 Inhibits Vascular Permeability, Angiogenesis, and Growth of Hepatic Colon Cancer Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Ovarian Carcinoma Develops through Multiple Modes of Chromosomal Evolution1
Mattias Höglund; David Gisselsson; Gunnar B. Hansen; Torbjörn Säll; Felix Mitelman
View articletitled, Ovarian Carcinoma Develops through Multiple Modes of Chromosomal Evolution<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Gatekeeper Effect of Epithelial-Mesenchymal Transition Regulates the Frequency of Breast Cancer Metastasis1
Chengsen Xue; David Plieth; Christo Venkov; Carol Xu; Eric G. Neilson
View articletitled, The Gatekeeper Effect of Epithelial-Mesenchymal Transition Regulates the Frequency of Breast Cancer Metastasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Role of Ink4a/Arf in ErbB2 Mammary Gland Tumorigenesis1
Mark D’Amico; Kongming Wu; Dolores Di Vizio; Anne T. Reutens; Mark Stahl; Maofu Fu; Chris Albanese; Robert G. Russell; William J. Muller; Michael White; Abdissa Negassa; Han-Woong Lee; Ronald A. DePinho; Richard G. Pestell
View articletitled, The Role of <strong><em>Ink4a/Arf</em></strong> in ErbB2 Mammary Gland Tumorigenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor-derived Vascular Endothelial Growth Factor Up-Regulates Angiopoietin-2 in Host Endothelium and Destabilizes Host Vasculature, Supporting Angiogenesis in Ovarian Cancer1
Lin Zhang; Nuo Yang; Jin-Wan Park; Dionyssios Katsaros; Stefano Fracchioli; Gaoyuan Cao; Ann O’Brien-Jenkins; Thomas C. Randall; Stephen C. Rubin; George Coukos
View articletitled, Tumor-derived Vascular Endothelial Growth Factor Up-Regulates Angiopoietin-2 in Host Endothelium and Destabilizes Host Vasculature, Supporting Angiogenesis in Ovarian Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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2-Deoxy-d-Glucose-induced Cytotoxicity and Radiosensitization in Tumor Cells Is Mediated via Disruptions in Thiol Metabolism1
Xiao Lin; Fanjie Zhang; C. Matthew Bradbury; Aradhana Kaushal; Ling Li; Douglas R. Spitz; Rebecca L. Aft; David Gius
View articletitled, 2-Deoxy-<span class="small-caps">d</span>-Glucose-induced Cytotoxicity and Radiosensitization in Tumor Cells Is Mediated via Disruptions in Thiol Metabolism<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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c-Abl Stabilizes p73 by a Phosphorylation-augmented Interaction1
Kelvin K. C. Tsai; Zhi-Min Yuan
View articletitled, c-Abl Stabilizes p73 by a Phosphorylation-augmented Interaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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EphA2 Overexpression Decreases Estrogen Dependence and Tamoxifen Sensitivity1
Ming Lu; Kathy D. Miller; Yesim Gokmen-Polar; Meei-Huey Jeng; Michael S. Kinch
View articletitled, EphA2 Overexpression Decreases Estrogen Dependence and Tamoxifen Sensitivity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Dykellic Acid Inhibits Phorbol Myristate Acetate-induced Matrix Metalloproteinase-9 Expression by Inhibiting Nuclear Factor κB Transcriptional Activity1
Ju-Hyung Woo; Jong-Wook Park; Sung-Hee Lee; Young-Ho Kim; In Kyu Lee; Edward Gabrielson; Sang-Han Lee; Ho-Jae Lee; Yung-Hee Kho; Taeg Kyu Kwon
View articletitled, Dykellic Acid Inhibits Phorbol Myristate Acetate-induced Matrix Metalloproteinase-9 Expression by Inhibiting Nuclear Factor κB Transcriptional Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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E1A Oncogene-induced Sensitization of Human Tumor Cells to Innate Immune Defenses and Chemotherapy-induced Apoptosis in Vitro and in Vivo1,2
James L. Cook; Tanya A. Miura; David N. Iklé; Andrew M. Lewis, Jr.; John M. Routes
View articletitled, E1A Oncogene-induced Sensitization of Human Tumor Cells to Innate Immune Defenses and Chemotherapy-induced Apoptosis <strong><em>in Vitro</em></strong> and <strong><em>in Vivo</em></strong><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">,2</a></sup>
Supplementary data
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Errata

Errata
View articletitled, Errata
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Errata
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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