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Volume 62, Issue 2

15 January 2002

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ISSN 0008-5472

EISSN 1538-7445

Issue Sections

Advances in Brief
Biochemistry and Biophysics
Carcinogenesis
Experimental Therapeutics
Immunology
Molecular Biology and Genetics
Tumor Biology
Virology
Letters to the Editor

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

SEPTIN6, a Human Homologue to Mouse Septin6, Is Fused to MLL in Infant Acute Myeloid Leukemia with Complex Chromosomal Abnormalities Involving 11q23 and Xq24 1

Ryoichi Ono; Tomohiko Taki; Takeshi Taketani; Hiroyuki Kawaguchi; Masafumi Taniwaki; Takayuki Okamura; Keisei Kawa; Ryoji Hanada; Miyuki Kobayashi; Yasuhide Hayashi

Abstract

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NKX-3.1 Interacts with Prostate-derived Ets Factor and Regulates the Activity of the PSA Promoter 1

Hui Chen; Asit K. Nandi; Xiang Li; Charles J. Bieberich

Abstract

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Vascular Endothelial Growth Factor-A₁₆₅ Induces Progression of Melanoma Brain Metastases without Induction of Sprouting Angiogenesis 1

Benno Küsters; William P. J. Leenders; Pieter Wesseling; Debby Smits; Kiek Verrijp; Dirk J. Ruiter; Johannes P. W. Peters; Albert J. van der Kogel; Robert M. W. de Waal

Abstract

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The NH₂-Terminal and Conserved Region 2 Domains of Adenovirus E1A Mediate Two Distinct Mechanisms of Tumor Suppression 1

Jiong Deng; Freke Kloosterbooer; Weiya Xia; Mien-Chie Hung

Abstract

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Aberrant Promoter Methylation of Multiple Genes in Bronchial Brush Samples from Former Cigarette Smokers 1

Jean-Charles Soria; Marivonne Rodriguez; Diane D. Liu; J. Jack Lee; Waun Ki Hong; Li Mao

Abstract

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Effects of the Cyclooxygenase Inhibitor, Piroxicam, on Tumor Response, Apoptosis, and Angiogenesis in a Canine Model of Human Invasive Urinary Bladder Cancer 1

Sulma I. Mohammed; Peter F. Bennett; Bruce A. Craig; Nita W. Glickman; Anthony J. Mutsaers; Paul W. Snyder; William R. Widmer; Amalia E. DeGortari; Patty L. Bonney; Deborah W. Knapp

Abstract

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A Homozygous Germ-Line Mutation in the Human MSH2 Gene Predisposes to Hematological Malignancy and Multiple Café-au-Lait Spots 1

Darcy Whiteside; Ross McLeod; Gail Graham; Jamie L. Steckley; Karen Booth; Martin J. Somerville; Susan E. Andrew

Abstract

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Different Combinations of Biallelic APC Mutation Confer Different Growth Advantages in Colorectal Tumours 1

Jeremy P. Cheadle; Michael Krawczak; Meinir W. Thomas; Angela K. Hodges; Nada Al-Tassan; Nick Fleming; Julian R. Sampson

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Supplementary data

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Functional Evidence for a Metastasis Suppressor Gene for Rat Prostate Cancer within a 60-Kilobase Region on Human Chromosome 8p21-p12 1

Naoki Nihei; Natalya Kouprina; Vladimir Larionov; Junko Oshima; George M. Martin; Tomohiko Ichikawa; J. Carl Barrett

Abstract

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Quantitative Adenomatous Polyposis Coli Promoter Methylation Analysis in Tumor Tissue, Serum, and Plasma DNA of Patients with Lung Cancer 1

Henning Usadel; Jan Brabender; Kathy D. Danenberg; Carmen Jerónimo; Susan Harden; James Engles; Peter V. Danenberg; Stephen Yang; David Sidransky

Abstract

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Modulation of Signal Transducer and Activator of Transcription 3 Activities by p53 Tumor Suppressor in Breast Cancer Cells 1

Jiayuh Lin; Xiaohong Jin; Kori Rothman; Huey-Jen Lin; Huaijing Tang; William Burke

Abstract

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Green Tea Catechins Inhibit Vascular Endothelial Growth Factor Receptor Phosphorylation 1

Sylvie Lamy; Denis Gingras; Richard Béliveau

Abstract

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Inhibition of the Bcr-Abl Oncoprotein by Bcr Requires Phosphoserine 354 1

Natalyn Hawk; Tong Sun; Shanhai Xie; Yan Wang; Yun Wu; Jiaxin Liu; Ralph B. Arlinghaus

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Biochemistry and Biophysics

In Vivo Analysis of Human Multidrug Resistance Protein 1 (MRP1) Activity Using Transient Expression of Fluorescently Tagged MRP1 1

Asha Rajagopal; Alok C. Pant; Sanford M. Simon; Yu Chen

Abstract

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Suppression of Ovarian Carcinoma Cell Growth in Vivo by the Interferon-inducible Plasma Membrane Protein, Phospholipid Scramblase 1 1

Robert H. Silverman; Ammar Halloum; Aimin Zhou; Beihua Dong; Fahad Al-Zoghaibi; David Kushner; Quansheng Zhou; Ji Zhao; Therese Wiedmer; Peter J. Sims

Abstract

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Carcinogenesis

Prostaglandin E₂ Protects Intestinal Tumors from Nonsteroidal Anti-inflammatory Drug-induced Regression in Apc^Min/+ Mice 1

Melissa B. Hansen-Petrik; Michael F. McEntee; Brian Jull; Hang Shi; Michael B. Zemel; Jay Whelan

Abstract

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Loss of Wnt-5a Protein Is Associated with Early Relapse in Invasive Ductal Breast Carcinomas 1

Marzieh Jönsson; Janna Dejmek; Pär-Ola Bendahl; Tommy Andersson

Abstract

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Interleukin-1α Up-Regulation in Vivo by a Potent Carcinogen 7,12-Dimethylbenz(a)anthracene (DMBA) and Control of DMBA-induced Inflammatory Responses 1

Xiaolu Li; Jonathan Eckard; Rajendra Shah; Chenlu Malluck; Krystyna Frenkel

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Cyclooxygenase-1 Is Up-Regulated in Cervical Carcinomas: Autocrine/Paracrine Regulation of Cyclooxygenase-2, Prostaglandin E Receptors, and Angiogenic Factors by Cyclooxygenase-1

Kurt J. Sales; Arieh A. Katz; Bruce Howard; Roggert P. Soeters; Robert P. Millar; Henry N. Jabbour

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n-6 Polyunsaturated Fatty Acids Increase Skin but not Cervical Cancer in Human Papillomavirus 16 Transgenic Mice 1

Mei Qi; DaZhi Chen; Kai Liu; Karen J. Auborn

Abstract

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Experimental Therapeutics

Targeting HER-2/neu with Antirat Neu Virosomes for Cancer Therapy 1

Ernst Waelti; Nina Wegmann; Ruth Schwaninger; Antionette Wetterwald; Carsten Wingenfeld; Barbara Rothen-Rutishauser; Claude D. Gimmi

Abstract

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Copper-64-pyruvaldehyde-bis(N⁴-methylthiosemicarbazone) for the Prevention of Tumor Growth at Wound Sites following Laparoscopic Surgery: Monitoring Therapy Response with microPET and Magnetic Resonance Imaging 1

Jason S. Lewis; Judith M. Connett; Joel R. Garbow; Thomas L. Buettner; Yasuhisa Fujibayashi; James W. Fleshman; Michael J. Welch

Abstract

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Farnesyltransferase Inhibitors Reverse Ras-mediated Inhibition of Fas Gene Expression

Bin Zhang; George C. Prendergast; Robert G. Fenton

Abstract

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X-ray Repair Cross-Complementing Gene I Protein Plays an Important Role in Camptothecin Resistance

Shin-Young Park; Wing Lam; Yung-chi Cheng

Abstract

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Epothilone B Analogue (BMS-247550)-mediated Cytotoxicity through Induction of Bax Conformational Change in Human Breast Cancer Cells 1

Hirohito Yamaguchi; Shanthi R. Paranawithana; Michael W. Lee; Ziwei Huang; Kapil N. Bhalla; Hong-Gang Wang

Abstract

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Immunology

Frequent Detection of Human Papillomavirus 16 E2-specific T-helper Immunity in Healthy Subjects 1

Annemieke de Jong; Sjoerd H. van der Burg; Kitty M. C. Kwappenberg; Jeanette M. van der Hulst; Kees L. M. C. Franken; Annemieke Geluk; Krista E. van Meijgaarden; Jan Wouter Drijfhout; Gemma Kenter; Pieter Vermeij; Cornelis J. M. Melief; Rienk Offringa

Abstract

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Retaliation against Tumor Cells Showing Aberrant HLA Expression Using Lymphokine Activated Killer-derived T Cells 1

Christine S. Falk; Elfriede Noessner; Elisabeth H. Weiss; Dolores J. Schendel

Abstract

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Molecular Biology and Genetics

Epidermal Growth Factor Protects Epithelial-derived Cells from Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis by Inhibiting Cytochrome c Release 1

Erika M. Gibson; Elizabeth S. Henson; Neil Haney; Jacylyn Villanueva; Spencer B. Gibson

Abstract

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Alterations of Smad Signaling in Human Breast Carcinoma Are Associated with Poor Outcome: A Tissue Microarray Study 1

Wen Xie; Joachim C. Mertens; Daniel J. Reiss; David L. Rimm; Robert L. Camp; Bruce G. Haffty; Michael Reiss

Abstract

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Cyclooxygenase 2- and Prostaglandin E₂ Receptor EP₂-dependent Angiogenesis in Apc^Δ716 Mouse Intestinal Polyps 1

Hiroshi Seno; Masanobu Oshima; Tomo-o Ishikawa; Hiroko Oshima; Kazuaki Takaku; Tsutomu Chiba; Shuh Narumiya; Makoto M. Taketo

Abstract

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Alterations of the Fragile Histidine Triad Gene, FHIT, and Its Encoded Products Contribute to Testicular Germ Cell Tumorigenesis 1

Sigrid Marie Kraggerud; Pierre Åman; Ruth Holm; Anna Elisabeth Stenwig; Sophie Dorothea Fosså; Jahn M. Nesland; Ragnhild A. Lothe

Abstract

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Genome-wide cDNA Microarray Screening to Correlate Gene Expression Profiles with Sensitivity of 85 Human Cancer Xenografts to Anticancer Drugs 1

Hitoshi Zembutsu; Yasuyuki Ohnishi; Tatsuhiko Tsunoda; Yoichi Furukawa; Toyomasa Katagiri; Yoshito Ueyama; Norikazu Tamaoki; Tatsuji Nomura; Osamu Kitahara; Rempei Yanagawa; Koichi Hirata; Yusuke Nakamura

Abstract

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Down-Regulation and Antiproliferative Role of C/EBPα in Lung Cancer 1

Balazs Halmos; Claudia S. Huettner; Olivier Kocher; Katalin Ferenczi; Daniel D. Karp; Daniel G. Tenen

Abstract

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Critical Role for Cyclin D2 in BCR/ABL-induced Proliferation of Hematopoietic Cells 1

Nilamani Jena; Ming Deng; Eva Sicinska; Piotr Sicinski; George Q. Daley

Abstract

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Human Semaphorin 3B (SEMA3B) Located at Chromosome 3p21.3 Suppresses Tumor Formation in an Adenocarcinoma Cell Line 1

Christin Tse; Ruinua H. Xiang; Todd Bracht; Susan L. Naylor

Abstract

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Lack of WRN Results in Extensive Deletion at Nonhomologous Joining Ends 1

Junko Oshima; Shurong Huang; Chong Pae; Judith Campisi; Robert H. Schiestl

Abstract

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Decreased B16F10 Melanoma Growth and Impaired Vascularization in Telomerase-deficient Mice with Critically Short Telomeres 1

Sonia Franco; Inmaculada Segura; Hans H. Riese; María A. Blasco

Abstract

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Tumor Biology

Hemodynamics in Vasculogenic Mimicry and Angiogenesis of Inflammatory Breast Cancer Xenograft 1

Kazuo Shirakawa; Hisataka Kobayashi; Yuji Heike; Satomi Kawamoto; Martin W. Brechbiel; Fujio Kasumi; Toshihiko Iwanaga; Fumio Konishi; Masaaki Terada; Hiro Wakasugi

Abstract

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SEL1L Expression Decreases Breast Tumor Cell Aggressiveness in Vivo and in Vitro1

Rosaria Orlandi; Monica Cattaneo; Flavia Troglio; Patrizia Casalini; Chiara Ronchini; Sylvie Ménard; Ida Biunno

Abstract

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Loss of the p21^Cip1/Waf1 Cyclin Kinase Inhibitor Results in Propagation of Horizontally Transferred DNA 1

Anna Bergsmedh; Anna Szeles; Anna-Lena Spetz; Lars Holmgren

Abstract

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Up-Regulation of Vascular Endothelial Growth Factor by Membrane-type 1 Matrix Metalloproteinase Stimulates Human Glioma Xenograft Growth and Angiogenesis 1

Elena I. Deryugina; Liliana Soroceanu; Alex Y. Strongin

Abstract

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Met Protein Expression Level Correlates with Survival in Patients with Late-stage Nasopharyngeal Carcinoma

Chao-Nan Qian; Xiang Guo; Brian Cao; Eric J. Kort; Chong-Chou Lee; Jindong Chen; Ling-Mei Wang; Wei-Yuan Mai; Hua-Qing Min; Ming-Huang Hong; George F. Vande Woude; James H. Resau; Bin Tean Teh

Abstract

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Quinazoline-derived α1-Adrenoceptor Antagonists Induce Prostate Cancer Cell Apoptosis Via an α1-Adrenoceptor-independent Action 1

Cynthia M. Benning; Natasha Kyprianou

Abstract

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Overexpression of Vascular Endothelial Growth Factor-A165 Enhances Tumor Angiogenesis but not Metastasis during β-Cell Carcinogenesis 1

Grainne Gannon; Stefano J. Mandriota; Lin Cui; Danielle Baetens; Michael S. Pepper; Gerhard Christofori

Abstract

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Virology

Adenovirus Targeting to c-erbB-2 Oncoprotein by Single-Chain Antibody Fused to Trimeric Form of Adenovirus Receptor Ectodomain 1

Elena A. Kashentseva; Toshiro Seki; David T. Curiel; Igor P. Dmitriev

Abstract

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Letters to the Editor

Pgp Immunochemistry: Use with Caution: Correspondence re: C-H. Kao et al., P-Glycoprotein and Multidrug Resistance-related Protein Expressions in Relation to Technetium-99m Methoxyisobutylisonitrile Scintimammography Findings. Cancer Res., 61: 1412–1414, 2001.

Anne Cayre; Jean Maublant; Frédérique Penault-Llorca

Extract

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Correspondence re: S. Beá et al., BMI-1 Gene Amplification and Overexpression in Hematological Malignancies Occur Mainly in Mantle Cell Lymphomas. Cancer Res., 61: 2409–2412, 2001

Frank M. Raaphorst; Chris J. L. M. Meijer; Arie P. Otte

Extract

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Issues

Cover Image

Journal Archive

Table of Contents

Advances in Brief

Biochemistry and Biophysics

Carcinogenesis

Experimental Therapeutics

Immunology

Molecular Biology and Genetics

Tumor Biology

Virology

Letters to the Editor

Email alerts

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