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Issues

Volume 61, Issue 5
3 March 2001
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Journal Archive

Cancer Research (1941-Present; volumes 1-current)

(ISSN 0008-5472) Published twice monthly since 1987. From 1941-1986, published monthly.

The American Journal of Cancer (1931-1940; volumes 15-40)

(ISSN 0099-7374) Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.

The Journal of Cancer Research (1916-1930); volumes 1-14)

(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Table of Contents

Advances in Brief

Breast Cancer Metastatic Potential Correlates with a Breakdown in Homospecific and Heterospecific Gap Junctional Intercellular Communication1
Marnie M. Saunders; M. Jabed Seraj; Zhongyong Li; Zhiyi Zhou; Cathy R. Winter; Danny R. Welch; Henry J. Donahue
View articletitled, Breast Cancer Metastatic Potential Correlates with a Breakdown in Homospecific and Heterospecific Gap Junctional Intercellular Communication<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The 104–123 Amino Acid Sequence of the β-domain of von Hippel-Lindau Gene Product Is Sufficient to Inhibit Renal Tumor Growth and Invasion1
Kaustubh Datta; Christian Sundberg; S. Ananth Karumanchi; Debabrata Mukhopadhyay
View articletitled, The 104–123 Amino Acid Sequence of the β-domain of von Hippel-Lindau Gene Product Is Sufficient to Inhibit Renal Tumor Growth and Invasion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Suppression of a Squamous Cell Carcinoma (SCC)-related Serpin, SCC Antigen, Inhibits Tumor Growth with Increased Intratumor Infiltration of Natural Killer Cells1
Yoshinori Suminami; Shigeki Nagashima; Akihiro Murakami; Shugo Nawata; Toshikazu Gondo; Hiroshi Hirakawa; Fumitaka Numa; Gary A. Silverman; Hiroshi Kato
View articletitled, Suppression of a Squamous Cell Carcinoma (SCC)-related Serpin, SCC Antigen, Inhibits Tumor Growth with Increased Intratumor Infiltration of Natural Killer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Noninvasive Imaging of αvβ3 Integrin Expression Using 18F-labeled RGD-containing Glycopeptide and Positron Emission Tomography1
Roland Haubner; Hans-Jürgen Wester; Wolfgang A. Weber; Christian Mang; Sibylle I. Ziegler; Simon L. Goodman; Reingard Senekowitsch-Schmidtke; Horst Kessler; Markus Schwaiger
View articletitled, Noninvasive Imaging of α<sub>v</sub>β<sub>3</sub> Integrin Expression Using <sup>18</sup>F-labeled RGD-containing Glycopeptide and Positron Emission Tomography<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth1
Terhi Karpanen; Mikala Egeblad; Marika J. Karkkainen; Hajime Kubo; Seppo Ylä-Herttuala; Marja Jäättelä; Kari Alitalo
View articletitled, Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Silica-induced Activation of c-Jun-NH2-Terminal Amino Kinases, Protracted Expression of the Activator Protein-1 Proto-Oncogene, fra-1, and S-Phase Alterations Are Mediated via Oxidative Stress1
Arti Shukla; Cynthia R. Timblin; Andrea K. Hubbard; Jonathan Bravman; Brooke T. Mossman
View articletitled, Silica-induced Activation of c-Jun-NH<sub>2</sub>-Terminal Amino Kinases, Protracted Expression of the Activator Protein-1 Proto-Oncogene, <em>fra-1</em>, and S-Phase Alterations Are Mediated via Oxidative Stress<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Adenovirus Expressing RIZ1 in Tumor Suppressor Gene Therapy of Microsatellite-unstable Colorectal Cancers1
Guang-Liang Jiang; Shi Huang
View articletitled, Adenovirus Expressing <em>RIZ1</em> in Tumor Suppressor Gene Therapy of Microsatellite-unstable Colorectal Cancers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Geldanamycin and Its Analogue 17-Allylamino-17-demethoxygeldanamycin Lowers Bcr-Abl Levels and Induces Apoptosis and Differentiation of Bcr-Abl-positive Human Leukemic Blasts
Ramadevi Nimmanapalli; Erica O’Bryan; Kapil Bhalla
View articletitled, Geldanamycin and Its Analogue 17-Allylamino-17-demethoxygeldanamycin Lowers Bcr-Abl Levels and Induces Apoptosis and Differentiation of Bcr-Abl-positive Human Leukemic Blasts
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Protease Pretreatment Increases the Efficacy of Adenovirus-mediated Gene Therapy for the Treatment of an Experimental Glioblastoma Model1
Nagato Kuriyama; Hiroko Kuriyama; Carol M. Julin; Kathleen R. Lamborn; Mark A. Israel
View articletitled, Protease Pretreatment Increases the Efficacy of Adenovirus-mediated Gene Therapy for the Treatment of an Experimental Glioblastoma Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Proline Oxidase, Encoded by p53-induced Gene-6, Catalyzes the Generation of Proline-dependent Reactive Oxygen Species
Steven P. Donald; Xiao-Ya Sun; Chien-An A. Hu; Jian Yu; Jay M. Mei; David Valle; James M. Phang
View articletitled, Proline Oxidase, Encoded by p53-induced Gene-6, Catalyzes the Generation of Proline-dependent Reactive Oxygen Species
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Tumorigenic Effect of Nonfunctional p53 or p21 in Mice Mutant in the Werner Syndrome Helicase1
Michel Lebel; Robert D. Cardiff; Philip Leder
View articletitled, Tumorigenic Effect of Nonfunctional p53 or p21 in Mice Mutant in the Werner Syndrome Helicase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Elevated Breast Cancer Risk in Irradiated BALB/c Mice Associates with Unique Functional Polymorphism of the Prkdc (DNA-dependent Protein Kinase Catalytic Subunit) Gene1
Yongjia Yu; Ryuichi Okayasu; Michael M. Weil; Andy Silver; Maureen McCarthy; Ryan Zabriskie; Scott Long; Roger Cox; Robert L. Ullrich
View articletitled, Elevated Breast Cancer Risk in Irradiated BALB/c Mice Associates with Unique Functional Polymorphism of the <em>Prkdc</em> (DNA-dependent Protein Kinase Catalytic Subunit) Gene<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Gene Expression Profiling with Oligonucleotide Microarrays Distinguishes World Health Organization Grade of Oligodendrogliomas1
Mark A. Watson; Arie Perry; Vikram Budhjara; Chindo Hicks; William D. Shannon; Keith M. Rich
View articletitled, Gene Expression Profiling with Oligonucleotide Microarrays Distinguishes World Health Organization Grade of Oligodendrogliomas<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Hypoxia Inducible Factor (HIF-1a and HIF-2a) Expression in Early Esophageal Cancer and Response to Photodynamic Therapy and Radiotherapy
Michael I. Koukourakis; Alexandra Giatromanolaki; John Skarlatos; Luigi Corti; Stella Blandamura; Mario Piazza; Kevin C. Gatter; Adrian L. Harris
View articletitled, Hypoxia Inducible Factor (HIF-1a and HIF-2a) Expression in Early Esophageal Cancer and Response to Photodynamic Therapy and Radiotherapy
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Invasion-specific Genes in Malignancy: Serial Analysis of Gene Expression Comparisons of Primary and Passaged Cancers1
Byungwoo Ryu; Jessa Jones; Michael A. Hollingsworth; Ralph H. Hruban; Scott E. Kern
View articletitled, Invasion-specific Genes in Malignancy<span class="subtitle-colon">: </span><span class="subtitle">Serial Analysis of Gene Expression Comparisons of Primary and Passaged Cancers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Aberrant Expression of HDMX Proteins in Tumor Cells Correlates with Wild-Type p53
Yolande F. M. Ramos; Robert Stad; Joline Attema; Lucy T. C. Peltenburg; Alex J. van der Eb; Aart G. Jochemsen
View articletitled, Aberrant Expression of HDMX Proteins in Tumor Cells Correlates with Wild-Type p53
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Somatic Mutation of Mitochondrial DNA in Cancerous and Noncancerous Liver Tissue in Individuals with Hepatocellular Carcinoma
Manabu Nishikawa; Shuhei Nishiguchi; Susumu Shiomi; Akihiro Tamori; Noritoshi Koh; Tadashi Takeda; Shoji Kubo; Kazuhiro Hirohashi; Hiroaki Kinoshita; Eisuke Sato; Masayasu Inoue
View articletitled, Somatic Mutation of Mitochondrial DNA in Cancerous and Noncancerous Liver Tissue in Individuals with Hepatocellular Carcinoma
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Target Cell-restricted Triggering of the CD95 (APO-1/Fas) Death Receptor with Bispecific Antibody Fragments1
Gundram Jung; Ludger Grosse-Hovest; Peter H. Krammer; Hans-Georg Rammensee
View articletitled, Target Cell-restricted Triggering of the CD95 (APO-1/Fas) Death Receptor with Bispecific Antibody Fragments<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Biochemistry and Biophysics

Increased Oxidative Stress in Ataxia Telangiectasia Evidenced by Alterations in Redox State of Brains from Atm-deficient Mice1
Ariel Kamsler; Dvorah Daily; Ayala Hochman; Nora Stern; Yosef Shiloh; Galit Rotman; Ari Barzilai
View articletitled, Increased Oxidative Stress in Ataxia Telangiectasia Evidenced by Alterations in Redox State of Brains from Atm-deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Phosphatidylinositol 3-Kinase Activity in Epidermal Growth Factor-stimulated Matrix Metalloproteinase-9 Production and Cell Surface Association1
Shawn M. Ellerbroek; Jennifer M. Halbleib; Mario Benavidez; Janel K. Warmka; Elizabeth V. Wattenberg; M. Sharon Stack; Laurie G. Hudson
View articletitled, Phosphatidylinositol 3-Kinase Activity in Epidermal Growth Factor-stimulated Matrix Metalloproteinase-9 Production and Cell Surface Association<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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XIAP Regulates Akt Activity and Caspase-3-dependent Cleavage during Cisplatin-induced Apoptosis in Human Ovarian Epithelial Cancer Cells1
Eric Asselin; Gordon B. Mills; Benjamin K. Tsang
View articletitled, XIAP Regulates Akt Activity and Caspase-3-dependent Cleavage during Cisplatin-induced Apoptosis in Human Ovarian Epithelial Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Rapid Release of Intracellular Galectin-3 from Breast Carcinoma Cells by Fetuin1
Wen-Qin Zhu; Josiah Ochieng
View articletitled, Rapid Release of Intracellular Galectin-3 from Breast Carcinoma Cells by Fetuin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Carcinogenesis

Sequential Analysis of Morphological and Biological Properties of β-Catenin-accumulated Crypts, Provable Premalignant Lesions Independent of Aberrant Crypt Foci in Rat Colon Carcinogenesis1
Yasuhiro Yamada; Naoki Yoshimi; Yoshinobu Hirose; Kengo Matsunaga; Masaki Katayama; Keiko Sakata; Masahito Shimizu; Toshiya Kuno; Hideki Mori
View articletitled, Sequential Analysis of Morphological and Biological Properties of β-Catenin-accumulated Crypts, Provable Premalignant Lesions Independent of Aberrant Crypt Foci in Rat Colon Carcinogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Clonal Growth Model: Time-course Simulations of Liver Foci Growth following Penta- or Hexachlorobenzene Treatment in a Medium-term Bioassay1
Ying C. Ou; Rory B. Conolly; Russell S. Thomas; Yihua Xu; Melvin E. Andersen; Laura S. Chubb; Henry C. Pitot; Raymond S. H. Yang
View articletitled, A Clonal Growth Model<span class="subtitle-colon">: </span><span class="subtitle">Time-course Simulations of Liver Foci Growth following Penta- or Hexachlorobenzene Treatment in a Medium-term Bioassay<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Clinical Investigations

erbB2 Overexpression on Occult Metastatic Cells in Bone Marrow Predicts Poor Clinical Outcome of Stage I–III Breast Cancer Patients1
Stephan Braun; Günter Schlimok; Isabella Heumos; Gerhard Schaller; Lutz Riethdorf; Gert Riethmüller; Klaus Pantel
View articletitled, erbB2 Overexpression on Occult Metastatic Cells in Bone Marrow Predicts Poor Clinical Outcome of Stage I–III Breast Cancer Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Heterogeneous Nuclear Ribonucleoprotein B1 as Early Cancer Biomarker for Occult Cancer of Human Lungs and Bronchial Dysplasia1
Eisaburo Sueoka; Naoko Sueoka; Yuri Goto; Satoru Matsuyama; Hitoshi Nishimura; Masami Sato; Shigefumi Fujimura; Hiroshige Chiba; Hirota Fujiki
View articletitled, Heterogeneous Nuclear Ribonucleoprotein B1 as Early Cancer Biomarker for Occult Cancer of Human Lungs and Bronchial Dysplasia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Key Importance of the Helicobacter pylori Adherence Factor Blood Group Antigen Binding Adhesin during Chronic Gastric Inflammation1
Christian Prinz; Martin Schöniger; Roland Rad; Ingrid Becker; Erwin Keiditsch; Stephan Wagenpfeil; Meinhard Classen; Thomas Rösch; Wolfgang Schepp; Markus Gerhard
View articletitled, Key Importance of the <em>Helicobacter pylori</em> Adherence Factor Blood Group Antigen Binding Adhesin during Chronic Gastric Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Endocrinology

Overexpression of Aromatase Leads to Hyperplasia and Changes in the Expression of Genes Involved in Apoptosis, Cell Cycle, Growth, and Tumor Suppressor Functions in the Mammary Glands of Transgenic Mice1
Nameer Kirma; Kiran Gill; Usha Mandava; Rajeshwar Rao Tekmal
View articletitled, Overexpression of Aromatase Leads to Hyperplasia and Changes in the Expression of Genes Involved in Apoptosis, Cell Cycle, Growth, and Tumor Suppressor Functions in the Mammary Glands of Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Evaluation of Androgen, Estrogen (ERα and ERβ), and Progesterone Receptor Expression in Human Prostate Cancer by Real-Time Quantitative Reverse Transcription-Polymerase Chain Reaction Assays
Alain Latil; Ivan Bièche; Dominique Vidaud; Rosette Lidereau; Philippe Berthon; Olivier Cussenot; Michel Vidaud
View articletitled, Evaluation of Androgen, Estrogen (<em>ERα</em> and <em>ERβ</em>), and Progesterone Receptor Expression in Human Prostate Cancer by Real-Time Quantitative Reverse Transcription-Polymerase Chain Reaction Assays
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Epidemiology and Prevention

Modulation of Experimental Colon Tumorigenesis by Types and Amounts of Dietary Fatty Acids1
Chinthalapally V. Rao; Yoshinobu Hirose; Cooma Indranie; Bandaru S. Reddy
View articletitled, Modulation of Experimental Colon Tumorigenesis by Types and Amounts of Dietary Fatty Acids<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Human Papillomavirus 16 and 18 L1 Serology Compared across Anogenital Cancer Sites1
Joseph J. Carter; Margaret M. Madeleine; Katherine Shera; Stephen M. Schwartz; Kara L. Cushing-Haugen; Gregory C. Wipf; Peggy Porter; Janet R. Daling; James K. McDougall; Denise A. Galloway
View articletitled, Human Papillomavirus 16 and 18 L1 Serology Compared across Anogenital Cancer Sites<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Therapeutics

Localization of a Human Reduced Folate Carrier Protein in the Mitochondrial as Well as the Cell Membrane of Leukemia Cells1
Tanya M. Trippett; Shawna Garcia; Katia Manova; Roshni Mody; Leona Cohen-Gould; Wayne Flintoff; Joseph R. Bertino
View articletitled, Localization of a Human Reduced Folate Carrier Protein in the Mitochondrial as Well as the Cell Membrane of Leukemia Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Vascular Attack by 5,6-Dimethylxanthenone-4-acetic Acid Combined with B7.1 (CD80)-mediated Immunotherapy Overcomes Immune Resistance and Leads to the Eradication of Large Tumors and Multiple Tumor Foci1
Jagat R. Kanwar; Rupinder K. Kanwar; Sushil Pandey; Lai-Ming Ching; Geoffrey W. Krissansen
View articletitled, Vascular Attack by 5,6-Dimethylxanthenone-4-acetic Acid Combined with B7.1 (CD80)-mediated Immunotherapy Overcomes Immune Resistance and Leads to the Eradication of Large Tumors and Multiple Tumor Foci<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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p53 Effects Both the Duration of G2/M Arrest and the Fate of Temozolomide-treated Human Glioblastoma Cells1
Yuichi Hirose; Mitchel S. Berger; Russell O. Pieper
View articletitled, p53 Effects Both the Duration of G<sub>2</sub>/M Arrest and the Fate of Temozolomide-treated Human Glioblastoma Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Characterization of a Novel Topoisomerase I Mutation from a Camptothecin-resistant Human Prostate Cancer Cell Line
Yoshimasa Urasaki; Gary S. Laco; Phillipe Pourquier; Yuji Takebayashi; Glenda Kohlhagen; Christopher Gioffre; Hongliang Zhang; Devasis Chatterjee; Panayotis Pantazis; Yves Pommier
View articletitled, Characterization of a Novel Topoisomerase I Mutation from a Camptothecin-resistant Human Prostate Cancer Cell Line
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Targeting of Aluminum (III) Phthalocyanine Tetrasulfonate by Use of Internalizing Monoclonal Antibodies: Improved Efficacy in Photodynamic Therapy
Maarten B. Vrouenraets; Gerard W. M. Visser; Marijke Stigter; Hugo Oppelaar; Gordon B. Snow; Guus A. M. S. van Dongen
View articletitled, Targeting of Aluminum (III) Phthalocyanine Tetrasulfonate by Use of Internalizing Monoclonal Antibodies<span class="subtitle-colon">: </span><span class="subtitle">Improved Efficacy in Photodynamic Therapy</span>
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T-Cell Activation by Recombinant Receptors: CD28 Costimulation Is Required for Interleukin 2 Secretion and Receptor-mediated T-Cell Proliferation but Does Not Affect Receptor-mediated Target Cell Lysis1
Andreas Hombach; Dagmar Sent; Claudia Schneider; Claudia Heuser; Dimitra Koch; Christoph Pohl; Barbara Seliger; Hinrich Abken
View articletitled, T-Cell Activation by Recombinant Receptors<span class="subtitle-colon">: </span><span class="subtitle">CD28 Costimulation Is Required for Interleukin 2 Secretion and Receptor-mediated T-Cell Proliferation but Does Not Affect Receptor-mediated Target Cell Lysis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Pharmacological and Toxicological Aspects of 4-Demethoxy-3′-deamino-3′-aziridinyl-4′-methylsulphonyl-daunorubicin (PNU-159548): A Novel Antineoplastic Agent1
Cristina Geroni; Marina Ripamonti; Claudio Arrigoni; Francesco Fiorentini; Laura Capolongo; Donatella Moneta; Sergio Marchini; Paola Della Torre; Clara Albanese; Maria Grazia Lamparelli; Marina Ciomei; Rosaria Rossi; Michele Caruso
View articletitled, Pharmacological and Toxicological Aspects of 4-Demethoxy-3′-deamino-3′-aziridinyl-4′-methylsulphonyl-daunorubicin (PNU-159548)<span class="subtitle-colon">: </span><span class="subtitle">A Novel Antineoplastic Agent<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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4-Demethoxy-3′-deamino-3′-aziridinyl-4′-methylsulphonyl-daunorubicin (PNU-159548), a Novel Anticancer Agent Active against Tumor CellLines with Different Resistance Mechanisms1
Sergio Marchini; Giovanna Damia; Massimo Broggini; Giulia Pennella; Marina Ripamonti; Aurelio Marsiglio; Cristina Geroni
View articletitled, 4-Demethoxy-3′-deamino-3′-aziridinyl-4′-methylsulphonyl-daunorubicin (PNU-159548), a Novel Anticancer Agent Active against Tumor CellLines with Different Resistance Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Chronotherapy of Mouse Mammary Adenocarcinoma MA13/C with Docetaxel and Doxorubicin as Single Agents and in Combination1
T. G. Granda; E. Filipski; R. M. D’Attino; P. Vrignaud; A. Anjo; M. C. Bissery; F. Lévi
View articletitled, Experimental Chronotherapy of Mouse Mammary Adenocarcinoma MA13/C with Docetaxel and Doxorubicin as Single Agents and in Combination<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Effects of Chemotherapy by 1,3-Bis(2-chloroethyl)-1-nitrosourea on Single-Quantum- and Triple-Quantum-filtered 23Na and 31P Nuclear Magnetic Resonance of the Subcutaneously Implanted 9L Glioma1
Patrick M. Winter; Harish Poptani; Navin Bansal
View articletitled, Effects of Chemotherapy by 1,3-Bis(2-chloroethyl)-1-nitrosourea on Single-Quantum- and Triple-Quantum-filtered <sup>23</sup>Na and <sup>31</sup>P Nuclear Magnetic Resonance of the Subcutaneously Implanted 9L Glioma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Response of LNCaP Spheroids after Treatment with an α-Particle Emitter (213Bi)-labeled Anti-Prostate-specific Membrane Antigen Antibody (J591)1
Åse M. Ballangrud; Wei-Hong Yang; David E. Charlton; Michael R. McDevitt; Klaus A. Hamacher; Katherine S. Panageas; Dangshe Ma; Neil H. Bander; David A. Scheinberg; George Sgouros
View articletitled, Response of LNCaP Spheroids after Treatment with an α-Particle Emitter (<sup>213</sup>Bi)-labeled Anti-Prostate-specific Membrane Antigen Antibody (J591)<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Immunology

Vascular Endothelial Growth Factor Effects on Nuclear Factor-κB Activation in Hematopoietic Progenitor Cells1
Mikhail M. Dikov; Tsunehiro Oyama; Pingyan Cheng; Takamune Takahashi; Keiko Takahashi; Tanya Sepetavec; Byard Edwards; Yasushi Adachi; Sorena Nadaf; Thomas Daniel; Dmitry I. Gabrilovich; David P. Carbone
View articletitled, Vascular Endothelial Growth Factor Effects on Nuclear Factor-κB Activation in Hematopoietic Progenitor Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Stimulation of β1 Integrin Down-Regulates ICAM-1 Expression and ICAM-1-dependent Adhesion of Lung Cancer Cells through Focal Adhesion Kinase1
Manabu Yasuda; Yoshiya Tanaka; Masahito Tamura; Koichi Fujii; Masakazu Sugaya; Tomoko So; Mitsuhiro Takenoyama; Kosei Yasumoto
View articletitled, Stimulation of β<sub>1</sub> Integrin Down-Regulates ICAM-1 Expression and ICAM-1-dependent Adhesion of Lung Cancer Cells through Focal Adhesion Kinase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Divergent Effects of 4-1BB Antibodies on Antitumor Immunity and on Tumor-reactive T-Cell Generation1
Julian A. Kim; Bruce J. Averbook; Kathleen Chambers; Kevin Rothchild; Jorgen Kjaergaard; Robert Papay; Suyu Shu
View articletitled, Divergent Effects of 4-1BB Antibodies on Antitumor Immunity and on Tumor-reactive T-Cell Generation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Molecular Basis of T Cell-mediated Recognition of Pancreatic Cancer Cells1
Masaaki Ito; Shigeki Shichijo; Naotake Tsuda; Mika Ochi; Nanae Harashima; Norio Saito; Kyogo Itoh
View articletitled, Molecular Basis of T Cell-mediated Recognition of Pancreatic Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Melanoma Patients Respond to a Cytotoxic T Lymphocyte-defined Self-Peptide with Diverse and Nonoverlapping T-Cell Receptor Repertoires1
Pierre-Yves Dietrich; Paul R. Walker; Anne-Lise Quiquerez; Gaelle Perrin; Valerie Dutoit; Danielle Liénard; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
View articletitled, Melanoma Patients Respond to a Cytotoxic T Lymphocyte-defined Self-Peptide with Diverse and Nonoverlapping T-Cell Receptor Repertoires<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Identification of a Tissue-specific Putative Transcription Factor in Breast Tissue by Serological Screening of a Breast Cancer Library1
Dirk Jäger; Elisabeth Stockert; Ali O. Güre; Matthew J. Scanlan; Julia Karbach; Elke Jäger; Alexander Knuth; Lloyd J. Old; Yao-Tseng Chen
View articletitled, Identification of a Tissue-specific Putative Transcription Factor in Breast Tissue by Serological Screening of a Breast Cancer Library<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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T Cell-dependent Antitumor Immunity Mediated by Secondary Lymphoid Tissue Chemokine: Augmentation of Dendritic Cell-based Immunotherapy1
Christopher J. Kirk; Dennis Hartigan-O’Connor; Brian J. Nickoloff; Jeffrey S. Chamberlain; Martin Giedlin; Lea Aukerman; James J. Mulé
View articletitled, T Cell-dependent Antitumor Immunity Mediated by Secondary Lymphoid Tissue Chemokine<span class="subtitle-colon">: </span><span class="subtitle">Augmentation of Dendritic Cell-based Immunotherapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Molecular Biology and Genetics

Regulation of Growth and Tumorigenicity of Breast Cancer Cells by the Low Molecular Weight GTPase Rad and Nm231
Yu-Hua Tseng; David Vicent; Jianhua Zhu; Yulian Niu; Adewale Adeyinka; Julie S. Moyers; Peter H. Watson; C. Ronald Kahn
View articletitled, Regulation of Growth and Tumorigenicity of Breast Cancer Cells by the Low Molecular Weight GTPase Rad and Nm23<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Oct-2 and Bob-1 Deficiency in Hodgkin and Reed Sternberg Cells1
Daniel Re; Markus Müschen; Tahamtan Ahmadi; Claudia Wickenhauser; Andrea Staratschek-Jox; Udo Holtick; Volker Diehl; Jürgen Wolf
View articletitled, Oct-2 and Bob-1 Deficiency in Hodgkin and Reed Sternberg Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Activation of β-Catenin during Hepatocarcinogenesis in Transgenic Mouse Models: Relationship to Phenotype and Tumor Grade
Diego F. Calvisi; Valentina M. Factor; Roberto Loi; Snorri S. Thorgeirsson
View articletitled, Activation of β-Catenin during Hepatocarcinogenesis in Transgenic Mouse Models<span class="subtitle-colon">: </span><span class="subtitle">Relationship to Phenotype and Tumor Grade</span>
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Increased Loss of Chromosome 9p21 but not p16 Inactivation in Primary Non-Small Cell Lung Cancer from Smokers1
Montserrat Sanchez-Cespedes; P. Anthony Decker; Kara M. Doffek; Manel Esteller; William H. Westra; Enas A. Alawi; James G. Herman; Michael J. Demeure; David Sidransky; Steven A. Ahrendt
View articletitled, Increased Loss of Chromosome 9p21 but not <em>p16</em> Inactivation in Primary Non-Small Cell Lung Cancer from Smokers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Stabilized β-Catenin Immortalizes Colonic Epithelial Cells1
Rebecca A. Wagenaar; Howard C. Crawford; Lynn M. Matrisian
View articletitled, Stabilized β-Catenin Immortalizes Colonic Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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p27Kip11 Is Required for PTEN-induced G1 Growth Arrest
Alexander R. Gottschalk; Daniel Basila; Michelle Wong; Nicholas M. Dean; Christian H. Brandts; David Stokoe; Daphne A. Haas-Kogan
View articletitled, p27<sup>Kip1</sup><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup> Is Required for PTEN-induced G<sub>1</sub> Growth Arrest
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SMAD3 Represses Androgen Receptor-mediated Transcription1
Steven A. Hayes; Mark Zarnegar; Manju Sharma; Fajun Yang; Donna M. Peehl; Peter ten Dijke; Zijie Sun
View articletitled, SMAD3 Represses Androgen Receptor-mediated Transcription<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Mapping the Sites of Putative Tumor Suppressor Genes at 6p25 and 6p21.3 in Cervical Carcinoma: Occurrence of Allelic Deletions in Precancerous Lesions1
Anupam Chatterjee; Hugo Arias Pulido; Sanjay Koul; Nestor Beleño; Ana Perilla; Hector Posso; Mahesh Manusukhani; Vundavalli V. V. S. Murty
View articletitled, Mapping the Sites of Putative Tumor Suppressor Genes at 6p25 and 6p21.3 in Cervical Carcinoma<span class="subtitle-colon">: </span><span class="subtitle">Occurrence of Allelic Deletions in Precancerous Lesions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Microsatellite Instability Occurs in Distinct Subtypes of Pediatric but not Adult Central Nervous System Tumors1
Michelle Alonso; Richard Hamelin; Mimi Kim; Kara Porwancher; Tammy Sung; Preeti Parhar; Douglas C. Miller; Elizabeth W. Newcomb
View articletitled, Microsatellite Instability Occurs in Distinct Subtypes of Pediatric but not Adult Central Nervous System Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Genome-wide Analysis of Gene Expression in Human Hepatocellular Carcinomas Using cDNA Microarray: Identification of Genes Involved in Viral Carcinogenesis and Tumor Progression1
Hiroshi Okabe; Seiji Satoh; Tatsushi Kato; Osamu Kitahara; Renpei Yanagawa; Yoshio Yamaoka; Tatsuhiko Tsunoda; Yoichi Furukawa; Yusuke Nakamura
View articletitled, Genome-wide Analysis of Gene Expression in Human Hepatocellular Carcinomas Using cDNA Microarray<span class="subtitle-colon">: </span><span class="subtitle">Identification of Genes Involved in Viral Carcinogenesis and Tumor Progression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Tumor Biology

Expression of Vesicular Monoamine Transporters, Synaptosomal-associated Protein 25 and Syntaxin1: A Signature of Human Small Cell Lung Carcinoma1
Lothar Graff; Florian Castrop; Markus Bauer; Heinz Höfler; Manfred Gratzl
View articletitled, Expression of Vesicular Monoamine Transporters, Synaptosomal-associated Protein 25 and Syntaxin1<span class="subtitle-colon">: </span><span class="subtitle">A Signature of Human Small Cell Lung Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Angiopoietin-2 Is Related to Tumor Angiogenesis in Gastric Carcinoma: Possible in Vivo Regulation via Induction of Proteases1
Tsuyoshi Etoh; Hiroshi Inoue; Shinji Tanaka; Graham F. Barnard; Seigo Kitano; Masaki Mori
View articletitled, Angiopoietin-2 Is Related to Tumor Angiogenesis in Gastric Carcinoma<span class="subtitle-colon">: </span><span class="subtitle">Possible <em>in Vivo</em> Regulation via Induction of Proteases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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HuR, a RNA Stability Factor, Is Expressed in Malignant Brain Tumors and Binds to Adenine- and Uridine-rich Elements within the 3′ Untranslated Regions of Cytokine and Angiogenic Factor mRNAs1
L. Burt Nabors; G. Yancey Gillespie; Lualhati Harkins; Peter H. King
View articletitled, HuR, a RNA Stability Factor, Is Expressed in Malignant Brain Tumors and Binds to Adenine- and Uridine-rich Elements within the 3′ Untranslated Regions of Cytokine and Angiogenic Factor mRNAs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Gene for the Axonal Cell Adhesion Molecule TAX-1 Is Amplified and Aberrantly Expressed in Malignant Gliomas
David S. Rickman; Rachana Tyagi; Xiao-Xiang Zhu; Miroslav P. Bobek; Suzan Song; Mila Blaivas; David E. Misek; Mark A. Israel; David M. Kurnit; Donald A. Ross; Phillip E. Kish; Samir M. Hanash
View articletitled, The Gene for the Axonal Cell Adhesion Molecule <em>TAX-1</em> Is Amplified and Aberrantly Expressed in Malignant Gliomas
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Expression of erbB-4/HER-4 Growth Factor Receptor Isoforms in Ovarian Cancer
Lynn M. R. Gilmour; Kenneth G. Macleod; Alison McCaig; William J. Gullick; John F. Smyth; Simon P. Langdon
View articletitled, Expression of erbB-4/HER-4 Growth Factor Receptor Isoforms in Ovarian Cancer
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Establishment of a Novel Species- and Tissue-specific Metastasis Model of Human Prostate Cancer in Humanized Non-Obese Diabetic/Severe Combined Immunodeficient Mice Engrafted with Human Adult Lung and Bone1
Hiroyuki Yonou; Tomoyuki Yokose; Tomoyuki Kamijo; Naoki Kanomata; Takahiro Hasebe; Kanji Nagai; Tadashi Hatano; Yoshihide Ogawa; Atsushi Ochiai
View articletitled, Establishment of a Novel Species- and Tissue-specific Metastasis Model of Human Prostate Cancer in Humanized Non-Obese Diabetic/Severe Combined Immunodeficient Mice Engrafted with Human Adult Lung and Bone<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Up-Regulation of Bcl-2 in Microvascular Endothelial Cells Enhances Intratumoral Angiogenesis and Accelerates Tumor Growth1
Jacques E. Nör; Joan Christensen; Jianguo Liu; Martin Peters; David J. Mooney; Robert M. Strieter; Peter J. Polverini
View articletitled, Up-Regulation of Bcl-2 in Microvascular Endothelial Cells Enhances Intratumoral Angiogenesis and Accelerates Tumor Growth<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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High Cancer Cell Death in Syngeneic Tumors Developed in Host Mice Deficient for the Stromelysin-3 Matrix Metalloproteinase1
Anne Boulay; Régis Masson; Marie-Pierre Chenard; Mostapha El Fahime; Lydie Cassard; Jean-Pierre Bellocq; Catherine Sautèes-Fridman; Paul Basset; Marie-Christine Rio
View articletitled, High Cancer Cell Death in Syngeneic Tumors Developed in Host Mice Deficient for the Stromelysin-3 Matrix Metalloproteinase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Role of Phosphatidylinositol 3-Kinase-Akt Pathway in Nucleophosmin/Anaplastic Lymphoma Kinase-mediated Lymphomagenesis1
Artur Slupianek; Margaret Nieborowska-Skorska; Grazyna Hoser; Andrea Morrione; Miroslaw Majewski; Liquan Xue; Stephan W. Morris; Mariusz A. Wasik; Tomasz Skorski
View articletitled, Role of Phosphatidylinositol 3-Kinase-Akt Pathway in Nucleophosmin/Anaplastic Lymphoma Kinase-mediated Lymphomagenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Aberrant Activation of c-kit Protects Colon Carcinoma Cells against Apoptosis and Enhances Their Invasive Potential1
Graziella Bellone; Anna Carbone; Nadia Sibona; Ornella Bosco; Daniela Tibaudi; Carlo Smirne; Tiziana Martone; Claudia Gramigni; Michele Camandona; Giorgio Emanuelli; Ulrich Rodeck
View articletitled, Aberrant Activation of c-kit Protects Colon Carcinoma Cells against Apoptosis and Enhances Their Invasive Potential<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Radiation Therapy to a Primary Tumor Accelerates Metastatic Growth in Mice1
Kevin Camphausen; Marsha A. Moses; Wolf-Dietrich Beecken; Mohamed K. Khan; Judah Folkman; Michael S. O’Reilly
View articletitled, Radiation Therapy to a Primary Tumor Accelerates Metastatic Growth in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Centrosome Defects Can Account for Cellular and Genetic Changes That Characterize Prostate Cancer Progression1
German A. Pihan; Aruna Purohit; Janice Wallace; Raji Malhotra; Lance Liotta; Stephen J. Doxsey
View articletitled, Centrosome Defects Can Account for Cellular and Genetic Changes That Characterize Prostate Cancer Progression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Altered Expression of Ape1/ref-1 in Germ Cell Tumors and Overexpression in NT2 Cells Confers Resistance to Bleomycin and Radiation1
Kent A. Robertson; Heather A. Bullock; Yi Xu; Renee Tritt; Erika Zimmerman; Thomas M. Ulbright; Richard S. Foster; Lawrence H. Einhorn; Mark R. Kelley
View articletitled, Altered Expression of Ape1/ref-1 in Germ Cell Tumors and Overexpression in NT2 Cells Confers Resistance to Bleomycin and Radiation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Clinicopathological Significance of Core 2 β1,6-N-Acetylglucosaminyltransferase Messenger RNA Expressed in the Pulmonary Adenocarcinoma Determined by in Situ Hybridization1
Emi Machida; Jun Nakayama; Jun Amano; Minoru Fukuda
View articletitled, Clinicopathological Significance of Core 2 β1,6-<em>N</em>-Acetylglucosaminyltransferase Messenger RNA Expressed in the Pulmonary Adenocarcinoma Determined by <em>in Situ</em> Hybridization<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Inhibition of Angiogenesis and Tumor Growth by SCH221153, a Dual αvβ3 and αvβ5 Integrin Receptor Antagonist1
C. Chandra Kumar; Michael Malkowski; Zizhang Yin; Elena Tanghetti; Bo Yaremko; Terry Nechuta; Judy Varner; Ming Liu; Elizabeth M. Smith; Bernie Neustadt; Marco Presta; Lydia Armstrong
View articletitled, Inhibition of Angiogenesis and Tumor Growth by SCH221153, a Dual α<sub>v</sub>β<sub>3</sub> and α<sub>v</sub>β<sub>5</sub> Integrin Receptor Antagonist<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Probasin-Large T Antigen Transgenic Mouse Line Develops Prostate Adenocarcinoma and Neuroendocrine Carcinoma with Metastatic Potential1
Naoya Masumori; Tania Z. Thomas; Pierre Chaurand; Tom Case; Manik Paul; Susan Kasper; Richard M. Caprioli; Taiji Tsukamoto; Scott B. Shappell; Robert J. Matusik
View articletitled, A Probasin-Large T Antigen Transgenic Mouse Line Develops Prostate Adenocarcinoma and Neuroendocrine Carcinoma with Metastatic Potential<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Necrosis Factor α and Interleukin 11 Secreted by Malignant Breast Epithelial Cells Inhibit Adipocyte Differentiation by Selectively Down-Regulating CCAAT/Enhancer Binding Protein α and Peroxisome Proliferator-activated Receptor γ: Mechanism of Desmoplastic Reaction1
Li Meng; Jianfeng Zhou; Hironobu Sasano; Takashi Suzuki; Khaled M. Zeitoun; Serdar E. Bulun
View articletitled, Tumor Necrosis Factor α and Interleukin 11 Secreted by Malignant Breast Epithelial Cells Inhibit Adipocyte Differentiation by Selectively Down-Regulating CCAAT/Enhancer Binding Protein α and Peroxisome Proliferator-activated Receptor γ<span class="subtitle-colon">: </span><span class="subtitle">Mechanism of Desmoplastic Reaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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The Expression of Vascular Endothelial Growth Factor Correlates with Mutant p53 and Poor Prognosis in Human Breast Cancer1
Barbro K. Linderholm; Thomas Lindahl; Lars Holmberg; Sigrid Klaar; Johan Lennerstrand; Roger Henriksson; Jonas Bergh
View articletitled, The Expression of Vascular Endothelial Growth Factor Correlates with Mutant <em>p53</em> and Poor Prognosis in Human Breast Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Impaired α-Interferon Signaling in Transitional Cell Carcinoma: Lack of p48 Expression in 5637 Cells1
Surena F. Matin; Raymond R. Rackley; Provash C. Sadhukhan; Myung S. Kim; Andrew C. Novick; Sudip K. Bandyopadhyay
View articletitled, Impaired α-Interferon Signaling in Transitional Cell Carcinoma<span class="subtitle-colon">: </span><span class="subtitle">Lack of p48 Expression in 5637 Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Induction of ETS-1 and ETS-2 Transcription Factors Is Required for Thyroid Cell Transformation1
Filomena de Nigris; Tiziana Mega; Nicole Berger; Maria Vittoria Barone; Massimo Santoro; Giuseppe Viglietto; Pasquale Verde; Alfredo Fusco
View articletitled, Induction of ETS-1 and ETS-2 Transcription Factors Is Required for Thyroid Cell Transformation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Regulation of MMP-1 and MMP-2 Production through CD147/Extracellular Matrix Metalloproteinase Inducer Interactions1
Jianxin Sun; Martin E. Hemler
View articletitled, Regulation of MMP-1 and MMP-2 Production through CD147/Extracellular Matrix Metalloproteinase Inducer Interactions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Parathyroid Hormone-related Protein Induces Interleukin 8 Production by Prostate Cancer Cells via a Novel Intracrine Mechanism Not Mediated by its Classical Nuclear Localization Sequence1
Aneeta Gujral; Douglas W. Burton; Robert Terkeltaub; Leonard J. Deftos
View articletitled, Parathyroid Hormone-related Protein Induces Interleukin 8 Production by Prostate Cancer Cells via a Novel Intracrine Mechanism Not Mediated by its Classical Nuclear Localization Sequence<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Farnesyltransferase Inhibitor L744,832 Reduces Hypoxia in Tumors Expressing Activated H-ras1
Elizabeth Cohen-Jonathan; Sydney M. Evans; Cameron J. Koch; Ruth J. Muschel; W. Gillies McKenna; JunMin Wu; Eric J. Bernhard
View articletitled, The Farnesyltransferase Inhibitor L744,832 Reduces Hypoxia in Tumors Expressing Activated H-<em>ras</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Cystemustine Induces Redifferentiation of Primary Tumors and Confers Protection against Secondary Tumor Growth in a Melanoma Murine Model1
Aicha Demidem; Daniel Morvan; Janine Papon; Monique De Latour; Jean Claude Madelmont
View articletitled, Cystemustine Induces Redifferentiation of Primary Tumors and Confers Protection against Secondary Tumor Growth in a Melanoma Murine Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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EphA2 Overexpression Causes Tumorigenesis of Mammary Epithelial Cells1
Daniel P. Zelinski; Nicole Dodge Zantek; Jane C. Stewart; Armando R. Irizarry; Michael S. Kinch
View articletitled, EphA2 Overexpression Causes Tumorigenesis of Mammary Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Distribution and Functional Consequences of Nucleotide Polymorphisms in the 3′-Untranslated Region of the Human Sep15 Gene1
Ya Jun Hu; Konstantin V. Korotkov; Rajeshwari Mehta; Dolph L. Hatfield; Charles N. Rotimi; Amy Luke; T. Elaine Prewitt; Richard S. Cooper; Wendy Stock; Everett E. Vokes; M. Eileen Dolan; Vadim N. Gladyshev; Alan M. Diamond
View articletitled, Distribution and Functional Consequences of Nucleotide Polymorphisms in the 3′-Untranslated Region of the Human <em>Sep15</em> Gene<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Up- and Down-Regulation of Granulocyte/Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms1
Amrit Mann; Kai Breuhahn; Peter Schirmacher; Arnd Wilhelmi; Carsten Beyer; Andrea Rosenau; Suat Özbek; Stefan Rose-John; Manfred Blessing
View articletitled, Up- and Down-Regulation of Granulocyte/Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Elevation of Breast Carcinoma Nm23-H1 Metastasis Suppressor Gene Expression and Reduced Motility by DNA Methylation Inhibition
Melanie T. Hartsough; Susan E. Clare; Michael Mair; Abdel G. Elkahloun; Dennis Sgroi; C. Kent Osborne; Gary Clark; Patricia S. Steeg
View articletitled, Elevation of Breast Carcinoma Nm23-H1 Metastasis Suppressor Gene Expression and Reduced Motility by DNA Methylation Inhibition
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Malignant Breast Epithelial Cells Stimulate Aromatase Expression via Promoter II in Human Adipose Fibroblasts: An Epithelial-Stromal Interaction in Breast Tumors Mediated by CCAAT/Enhancer Binding Protein β1
Jianfeng Zhou; Bilgin Gurates; Sijun Yang; Siby Sebastian; Serdar E. Bulun
View articletitled, Malignant Breast Epithelial Cells Stimulate Aromatase Expression via Promoter II in Human Adipose Fibroblasts<span class="subtitle-colon">: </span><span class="subtitle">An Epithelial-Stromal Interaction in Breast Tumors Mediated by CCAAT/Enhancer Binding Protein β<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup></span>
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Letters to the Editor

Correspondence re: O. J. Arola et al., Acute Doxorubicin Cardiotoxicity Involves Cardiomyocyte Apoptosis. Cancer Res., 60: 1789–1792, 2000.
Holger W. Auner; Christoph Tinchon; Werner Linkesch; Gabriele Halwachs-Baumann; Heinz Sill
View articletitled, Correspondence re: O. J. Arola <em>et al.</em>, Acute Doxorubicin Cardiotoxicity Involves Cardiomyocyte Apoptosis. Cancer Res., <em>60:</em> 1789–1792, 2000.
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Errata

H. Sjögren et al., Cancer Res., 60:6832–6835, 2000
View articletitled, H. Sjögren <em>et al.</em>, Cancer Res., <em>60:</em>6832–6835, 2000
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  • Online ISSN 1538-7445
  • Print ISSN 0008-5472

AACR Journals

 

 

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