(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

Isolation of a Peptide for Targeted Drug Delivery into Human Head and Neck Solid Tumors 1

Frank D. Hong; Gary L. Clayman

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Tumor Metastasis and the Reciprocal Regulation of Prometastatic and Antimetastatic Factors by Nuclear Factor κB

Valentine B. Andela; Edward M. Schwarz; J. Edward Puzas; Regis J. O’Keefe; Randy N. Rosier

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WISH-PC2: A Unique Xenograft Model of Human Prostatic Small Cell Carcinoma 1

Jehonathan H. Pinthus; Tova Waks; Daniel G. Schindler; Alon Harmelin; Jonathan W. Said; Arie Belldegrun; Jacob Ramon; Zelig Eshhar

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PSGR, a Novel Prostate-specific Gene with Homology to a G Protein-coupled Receptor, Is Overexpressed in Prostate Cancer 1

Linda L. Xu; Bennett G. Stackhouse; Kim Florence; Wei Zhang; Naga Shanmugam; Iasbell A. Sesterhenn; Zhiqiang Zou; Vasantha Srikantan; Meena Augustus; Viktor Roschke; Kenneth Carter; David G. McLeod; Judd W. Moul; Dan Soppett; Shiv Srivastava

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In Vitro Sensitivity of T-Cell Lymphoblastic Leukemia to UCN-01 (7-Hydroxystaurosporine) Is Dependent on p16 Protein Status: A Pediatric Oncology Group Study 1

Motoko Omura-Minamisawa; Mitchell B. Diccianni; Ayse Batova; Ray C. Chang; Louis J. Bridgeman; John Yu; Esther de Wit; Faith H. Kung; Jeanette D. Pullen; Alice L. Yu

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Activity of a Novel Camptothecin Analogue, Homocamptothecin, in Camptothecin-resistant Cell Lines with Topoisomerase I Alterations

Yoshimasa Urasaki; Yuji Takebayashi; Yves Pommier

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DLC-1 Is Deleted in Primary Hepatocellular Carcinoma and Exerts Inhibitory Effects on the Proliferation of Hepatoma Cell Lines with Deleted DLC-11

Irene Oi-lin Ng; Zheng-dong Liang; Liang Cao; Terence Kin-wah Lee

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RB18A, Whose Gene Is Localized on Chromosome 17q12-q21.1, Regulates in Vivo p53 Transactivating Activity 1

Raymond Frade; Michelle Balbo; Monique Barel

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Neutral Endopeptidase Promotes Phorbol Ester-induced Apoptosis in Prostate Cancer Cells by Inhibiting Neuropeptide-induced Protein Kinase C δ Degradation 1

Makoto Sumitomo; Ruoqian Shen; Jonathan S. Goldberg; Jie Dai; Daniel Navarro; David M. Nanus

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Direct Evidence for the Contribution of Activated N-ras and K-ras Oncogenes to Increased Intrinsic Radiation Resistance in Human Tumor Cell Lines 1

Eric J. Bernhard; Eric J. Stanbridge; Swati Gupta; Anjali K. Gupta; Daniel Soto; Vincent J. Bakanauskas; George J. Cerniglia; Ruth J. Muschel; W. Gillies McKenna

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Biochemistry and Biophysics

Pharmacodynamics of Tamoxifen and Its 4-Hydroxy and N-Desmethyl Metabolites: Activation of Caspases and Induction of Apoptosis in Rat Mammary Tumors and in Human Breast Cancer Cell Lines 1

Sandhya Mandlekar; Vidya Hebbar; Konstantin Christov; A-N. Tony Kong

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Carcinogenesis

Sulindac Sulfone Inhibits K-ras-dependent Cyclooxygenase-2 Expression in Human Colon Cancer Cells 1

Michele T. Taylor; Kathryn R. Lawson; Natalia A. Ignatenko; Sarah E. Marek; David E. Stringer; Beth A. Skovan; Eugene W. Gerner

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Mutations of Adenomatous Polyposis Coli and β-Catenin Genes during Progression of Lung Tumors Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats 1

Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yasutaka Sasaki; Nao Murata; Yoichi Konishi

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Clinical Investigations

Identification of Differentially Expressed Genes in Human Gliomas by DNA Microarray and Tissue Chip Techniques

Satu-Leena Sallinen; Pauli K. Sallinen; Hannu K. Haapasalo; Heikki J. Helin; Pauli T. Helén; Peter Schraml; Olli-P. Kallioniemi; Juha Kononen

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Allelic Deletions of Cell Growth Regulators during Progression of Bladder Cancer 1

Hanne Primdahl; Hans von der Maase; Mariann Christensen; Hans Wolf; Torben F. Ørntoft

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Endocrinology

Antiandrogenic Effects of Novel Androgen Synthesis Inhibitors on Hormone-dependent Prostate Cancer 1

Brian J. Long; Dmitry N. Grigoryev; Ivo P. Nnane; Yang Liu; Yang-Zhi Ling; Angela M. Brodie

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Experimental Therapeutics

Locoregional Cancer Treatment with Magnetic Drug Targeting 1

Christoph Alexiou; Wolfgang Arnold; Roswitha J. Klein; Fritz G. Parak; Peter Hulin; Christian Bergemann; Wolfgang Erhardt; Stefan Wagenpfeil; Andreas S. Lübbe

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Yeast Cytosine Deaminase Improves Radiosensitization and Bystander Effect by 5-Fluorocytosine of Human Colorectal Cancer Xenografts 1

Els Kievit; Mukesh K. Nyati; Emily Ng; Lauren D. Stegman; Josh Parsels; Brian D. Ross; Alnawaz Rehemtulla; Theodore S. Lawrence

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Tyrosinase Mutants Are Capable of Prodrug Activation in Transfected Nonmelanotic Cells 1

Maria Simonova; Alexander Wall; Ralph Weissleder; Alexei Bogdanov, Jr.

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A Tetravalent Single-chain Antibody-Streptavidin Fusion Protein for Pretargeted Lymphoma Therapy 1

Jody Schultz; Yukang Lin; James Sanderson; Yuting Zuo; Diane Stone; Robert Mallett; Sibylle Wilbert; Donald Axworthy

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Molecular Biology and Genetics

Suppression of Ganglioside GD3 Expression in a Rat F-11 Tumor Cell Line Reduces Tumor Growth, Angiogenesis, and Vascular Endothelial Growth Factor Production 1

Guichao Zeng; Luoyi Gao; Stéphane Birklé; Robert K. Yu

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Identification of a 6-cM Minimal Deletion at 11q23.1–23.2 and Exclusion of PPP2R1B Gene as a Deletion Target in Cervical Cancer 1

Hugo Arias Pulido; Mohamed J. Fakruddin; Anupam Chatterjee; Edward D. Esplin; Nestor Beleño; Gilberto Martínez; Hector Posso; Glen A. Evans; V. V. V. S. Murty

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Down-Regulation of Monocyte Chemotactic Protein-3 by Activated β-Catenin

Manabu Fujita; Yoichi Furukawa; Yutaka Nagasawa; Michio Ogawa; Yusuke Nakamura

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Thioredoxin Nuclear Translocation and Interaction with Redox Factor-1 Activates the Activator Protein-1 Transcription Factor in Response to Ionizing Radiation 1

S. Jack Wei; Ana Botero; Kiichi Hirota; C. Matthew Bradbury; Stephanie Markovina; Andrei Laszlo; Douglas R. Spitz; Prabhat C. Goswami; Junji Yodoi; David Gius

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Tumor Biology

Mice Vaccination with Interleukin 12-transduced Colon Cancer Cells Potentiates Rejection of Syngeneic Non-Organ-related Tumor Cells 1

Soraya Adris; Eduardo Chuluyan; Alicia Bravo; Mariana Berenstein; Slovodanka Klein; Maria Jasnis; Cecilia Carbone; Yuti Chernajovsky; Osvaldo L. Podhajcer

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Dissociation of Staurosporine-induced Apoptosis from G₂-M Arrest in SW620 Human Colonic Carcinoma Cells: Initiation of the Apoptotic Cascade Is Associated with Elevation of the Mitochondrial Membrane Potential (Δψ_m)1

Barbara G. Heerdt; Michele A. Houston; John M. Mariadason; Leonard H. Augenlicht

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The CD24/P-selectin Binding Pathway Initiates Lung Arrest of Human A125 Adenocarcinoma Cells 1

Jan Friederichs; Yvonka Zeller; Ali Hafezi-Moghadam; Hermann-Josef Gröne; Klaus Ley; Peter Altevogt

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Antiangiogenic Effects of Latent Antithrombin through Perturbed Cell-Matrix Interactions and Apoptosis of Endothelial Cells 1

Helena Larsson; Tobias Sjöblom; Johan Dixelius; Arne Östman; Karin Ylinenjärvi; Ingemar Björk; Lena Claesson-Welsh

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The Effect of Fibroblast Growth Factor 8, Isoform b, on the Biology of Prostate Carcinoma Cells and Their Interaction with Stromal Cells 1

Zhigang Song; William C. Powell; Noriyuki Kasahara; Adriaan van Bokhoven; Gary J. Miller; Pradip Roy-Burman

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HGF/NK4, a Four-Kringle Antagonist of Hepatocyte Growth Factor, Is an Angiogenesis Inhibitor that Suppresses Tumor Growth and Metastasis in Mice 1

Keiji Kuba; Kunio Matsumoto; Kazuhiko Date; Hideo Shimura; Masao Tanaka; Toshikazu Nakamura

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Differential Gene Expression between Normal and Tumor-derived Ovarian Epithelial Cells 1

Rubina S. Ismail; Rae Lynn Baldwin; Junguo Fang; Damaris Browning; Beth Y. Karlan; Judith C. Gasson; David D. Chang

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K-ras Codon 12 Mutation Induces Higher Level of Resistance to Apoptosis and Predisposition to Anchorage-independent Growth Than Codon 13 Mutation or Proto-Oncogene Overexpression 1

Sílvia Guerrero; Isolda Casanova; Lourdes Farré; Adela Mazo; Gabriel Capellà; Ramon Mangues

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Modulation of Tumor Angiogenesis by Stem Cell Factor 1

Wei Zhang; George Stoica; Serban I. Tasca; Katherine A. Kelly; Cynthia J. Meininger

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The Phosphatidylinositol 3-Kinase/AKT Kinase Pathway in Multiple Myeloma Plasma Cells: Roles in Cytokine-dependent Survival and Proliferative Responses 1

Yiping Tu; Agnes Gardner; Alan Lichtenstein

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