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Issues

Volume 60, Issue 22
15 November 2000
Issue Cover
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Advances in Brief

Duplication of the Mutant RET Allele in Trisomy 10 or Loss of the Wild-Type Allele in Multiple Endocrine Neoplasia Type 2-associated Pheochromocytomas
Steve C. Huang; Christian A. Koch; Alexander O. Vortmeyer; Svetlana D. Pack; Urs D. Lichtenauer; Poonam Mannan; Irina A. Lubensky; George P. Chrousos; Robert F. Gagel; Karel Pacak; Zhengping Zhuang
View articletitled, Duplication of the Mutant <em>RET</em> Allele in Trisomy 10 or Loss of the Wild-Type Allele in Multiple Endocrine Neoplasia Type 2-associated Pheochromocytomas
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t(9;11)(p22;p15) in Acute Myeloid Leukemia Results in a Fusion between NUP98 and the Gene Encoding Transcriptional Coactivators p52 and p75-Lens Epithelium-derived Growth Factor (LEDGF)1
Harish G. Ahuja; Jianming Hong; Peter D. Aplan; Lucene Tcheurekdjian; Stephen J. Forman; Marilyn L. Slovak
View articletitled, t(9;11)(p22;p15) in Acute Myeloid Leukemia Results in a Fusion between <em>NUP98</em> and the Gene Encoding Transcriptional Coactivators p52 and p75-Lens Epithelium-derived Growth Factor (<em>LEDGF</em>)<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Frequent Amplification of the Telomerase Reverse Transcriptase Gene in Human Tumors1
Anju Zhang; Chengyun Zheng; Charlotta Lindvall; Mi Hou; Jessica Ekedahl; Rolf Lewensohn; Zhongqun Yan; Xiaoyan Yang; Marie Henriksson; Elisabeth Blennow; Magnus Nordenskjöld; Anders Zetterberg; Magnus Björkholm; Astrid Gruber; Dawei Xu
View articletitled, Frequent Amplification of the <em>Telomerase Reverse Transcriptase</em> Gene in Human Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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TMS1, a Novel Proapoptotic Caspase Recruitment Domain Protein, Is a Target of Methylation-induced Gene Silencing in Human Breast Cancers1
Kerry E. Conway; Beth B. McConnell; Claire E. Bowring; Carlton D. Donald; Stephen T. Warren; Paula M. Vertino
View articletitled, <em>TMS1</em>, a Novel Proapoptotic Caspase Recruitment Domain Protein, Is a Target of Methylation-induced Gene Silencing in Human Breast Cancers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Activation of a Caspase-9-mediated Apoptotic Pathway by Subcellular Redistribution of the Novel Caspase Recruitment Domain Protein TMS11
Beth B. McConnell; Paula M. Vertino
View articletitled, Activation of a Caspase-9-mediated Apoptotic Pathway by Subcellular Redistribution of the Novel Caspase Recruitment Domain Protein TMS1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Vascular Endothelial Growth Factor (VEGF) Modulation by Targeting Hypoxia-inducible Factor-1α → Hypoxia Response Element → VEGF Cascade Differentially Regulates Vascular Response and Growth Rate in Tumors1
Yoshikazu Tsuzuki; Dai Fukumura; Bert Oosthuyse; Chieko Koike; Peter Carmeliet; Rakesh K. Jain
View articletitled, Vascular Endothelial Growth Factor (VEGF) Modulation by Targeting Hypoxia-inducible Factor-1α → Hypoxia Response Element → VEGF Cascade Differentially Regulates Vascular Response and Growth Rate in Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Complete Inhibition of Rhabdomyosarcoma Xenograft Growth and Neovascularization Requires Blockade of Both Tumor and Host Vascular Endothelial Growth Factor
Hans-Peter Gerber; Joe Kowalski; Daniel Sherman; David A. Eberhard; Napoleone Ferrara
View articletitled, Complete Inhibition of Rhabdomyosarcoma Xenograft Growth and Neovascularization Requires Blockade of Both Tumor and Host Vascular Endothelial Growth Factor
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The Caspase 9 Inhibitor Z-LEHD-FMK Protects Human Liver Cells while Permitting Death of Cancer Cells Exposed to Tumor Necrosis Factor-related Apoptosis-inducing Ligand
Nesrin Özören; Kunhong Kim; Timothy F. Burns; David T. Dicker; A. David Moscioni; Wafik S. El-Deiry
View articletitled, The Caspase 9 Inhibitor Z-LEHD-FMK Protects Human Liver Cells while Permitting Death of Cancer Cells Exposed to Tumor Necrosis Factor-related Apoptosis-inducing Ligand
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Altered Expression of Estrogen Receptor Coregulators during Human Breast Tumorigenesis1
Leigh C. Murphy; Sharon L. R. Simon; Alicia Parkes; Etienne Leygue; Helmut Dotzlaw; Linda Snell; Sandra Troup; Adewale Adeyinka; Peter H. Watson
View articletitled, Altered Expression of Estrogen Receptor Coregulators during Human Breast Tumorigenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4+ Cytolytic T Lymphocytes1
Erwin S. Schultz; Bernard Lethé; César L. Cambiaso; Jacques Van Snick; Pascal Chaux; Jurgen Corthals; Carlo Heirman; Kris Thielemans; Thierry Boon; Pierre van der Bruggen
View articletitled, A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4<sup>+</sup> Cytolytic T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Activation of the Transcription Factor Oct-1 in Response to DNA Damage
Hongcheng Zhao; Shunqian Jin; Feiyue Fan; Wenhong Fan; Tong Tong; Qimin Zhan
View articletitled, Activation of the Transcription Factor Oct-1 in Response to DNA Damage
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Large-Scale Serial Analysis of Gene Expression Reveals Genes Differentially Expressed in Ovarian Cancer1
Colleen D. Hough; Cheryl A. Sherman-Baust; Ellen S. Pizer; F. J. Montz; Dwight D. Im; Neil B. Rosenshein; Kathleen R. Cho; Gregory J. Riggins; Patrice J. Morin
View articletitled, Large-Scale Serial Analysis of Gene Expression Reveals Genes Differentially Expressed in Ovarian Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Frequent Association of β-Catenin and WT1 Mutations in Wilms Tumors1
Sourindra Maiti; Rita Alam; Christopher I. Amos; Vicki Huff
View articletitled, Frequent Association of <em>β</em><em>-Catenin</em> and <em>WT1</em> Mutations in Wilms Tumors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Loss of Annexin 1 Correlates with Early Onset of Tumorigenesis in Esophageal and Prostate Carcinoma
Cloud P. Paweletz; David K. Ornstein; Mark J. Roth; Verena E. Bichsel; John W. Gillespie; Valerie S. Calvert; Cathy D. Vocke; Stephen M. Hewitt; Paul H. Duray; Judi Herring; Quan-Hong Wang; Nan Hu; W. Marston Linehan; Phillip R. Taylor; Lance A. Liotta; Michael R. Emmert-Buck; Emanuel F. Petricoin, III
View articletitled, Loss of Annexin 1 Correlates with Early Onset of Tumorigenesis in Esophageal and Prostate Carcinoma
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Thymidine Phosphorylase Induces Carcinoma Cell Oxidative Stress and Promotes Secretion of Angiogenic Factors1
Nicholas S. Brown; Adam Jones; Chisato Fujiyama; Adrian L. Harris; Roy Bicknell
View articletitled, Thymidine Phosphorylase Induces Carcinoma Cell Oxidative Stress and Promotes Secretion of Angiogenic Factors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Oncogenic Potential of the High Mobility Group Box Protein Sox31
Yu Xia; Nancy Papalopulu; Peter K. Vogt; Jian Li
View articletitled, The Oncogenic Potential of the High Mobility Group Box Protein Sox3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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O6-Benzylguanine Potentiates the Antitumor Effect of Locally Delivered Carmustine against an Intracranial Rat Glioma1
Laurence D. Rhines; Prakash Sampath; M. Eileen Dolan; Betty M. Tyler; Henry Brem; Jon Weingart
View articletitled, <em>O</em><sup>6</sup>-Benzylguanine Potentiates the Antitumor Effect of Locally Delivered Carmustine against an Intracranial Rat Glioma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Somatic Mutations of LKB1 and β-Catenin Genes in Gastrointestinal Polyps from Patients with Peutz-Jeghers Syndrome1
Michiko Miyaki; Takeru Iijima; Keiko Hosono; Reiko Ishii; Masamichi Yasuno; Takeo Mori; Masakazu Toi; Tsunekazu Hishima; Nobuyuki Shitara; Kazuo Tamura; Joji Utsunomiya; Naoyuki Kobayashi; Toshio Kuroki; Takeo Iwama
View articletitled, Somatic Mutations of <em>LKB1</em> and <em>β</em><em>-Catenin</em> Genes in Gastrointestinal Polyps from Patients with Peutz-Jeghers Syndrome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Functional Analysis of Human Ornithine Decarboxylase Alleles1
Yongjun Guo; Robin B. Harris; Dan Rosson; David Boorman; Thomas G. O’Brien
View articletitled, Functional Analysis of Human Ornithine Decarboxylase Alleles<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Bax Is a Transcriptional Target and Mediator of c-Myc-induced Apoptosis1
Kyran O. Mitchell; M. Stacey Ricci; Toshiyuki Miyashita; David T. Dicker; Zhaoyu Jin; John C. Reed; Wafik S. El-Deiry
View articletitled, <em>Bax</em> Is a Transcriptional Target and Mediator of c-Myc-induced Apoptosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Biochemistry and Biophysics

Nitric Oxide Synthase Is Induced in Tumor Promoter-sensitive, but not Tumor Promoter-resistant, JB6 Mouse Epidermal Cells Cocultured with Interferon- γ-stimulated RAW 264.7 Cells: The Role of Tumor Necrosis Factor-α1
Akira Murakami; Kyuichi Kawabata; Teruaki Koshiba; Guanxin Gao; Yoshimasa Nakamura; Koichi Koshimizu; Hajime Ohigashi
View articletitled, Nitric Oxide Synthase Is Induced in Tumor Promoter-sensitive, but not Tumor Promoter-resistant, JB6 Mouse Epidermal Cells Cocultured with Interferon- γ-stimulated RAW 264.7 Cells: The Role of Tumor Necrosis Factor-α<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Activator Protein 1 Transcription Factors Are Fundamental to v-rasHa-induced Changes in Gene Expression in Neoplastic Keratinocytes
Susan E. Rutberg; Tracey L. Adams; Adam Glick; Maria T. Bonovich; Charles Vinson; Stuart H. Yuspa
View articletitled, Activator Protein 1 Transcription Factors Are Fundamental to v-<em>ras</em><sup><em>Ha</em></sup>-induced Changes in Gene Expression in Neoplastic Keratinocytes
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Carcinogeniesis

The RB1 Gene Is the Target of Chromosome 13 Deletions in Malignant Fibrous Histiocytoma1
Frédéric Chibon; Aline Mairal; Paul Fréneaux; Philippe Terrier; Jean-Michel Coindre; Xavier Sastre; Alain Aurias
View articletitled, The <em>RB1</em> Gene Is the Target of Chromosome 13 Deletions in Malignant Fibrous Histiocytoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Arsenite Induces p53 Accumulation through an ATM-dependent Pathway in Human Fibroblasts1
Ling-Huei Yih; Te-Chang Lee
View articletitled, Arsenite Induces p53 Accumulation through an ATM-dependent Pathway in Human Fibroblasts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Oleate Activates Phosphatidylinositol 3-Kinase and Promotes Proliferation and Reduces Apoptosis of MDA-MB-231 Breast Cancer Cells, Whereas Palmitate Has Opposite Effects1
Serge Hardy; Yves Langelier; Marc Prentki
View articletitled, Oleate Activates Phosphatidylinositol 3-Kinase and Promotes Proliferation and Reduces Apoptosis of MDA-MB-231 Breast Cancer Cells, Whereas Palmitate Has Opposite Effects<sup>1 </sup>
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Clinical Investigations

Selective Replication and Oncolysis in p53 Mutant Tumors with ONYX-015, an E1B-55kD Gene-deleted Adenovirus, in Patients with Advanced Head and Neck Cancer: A Phase II Trial
John Nemunaitis; Ian Ganly; Fadlo Khuri; James Arseneau; Joseph Kuhn; Todd McCarty; Stephen Landers; Phillip Maples; Larry Romel; Britta Randlev; Tony Reid; Sam Kaye; David Kirn
View articletitled, Selective Replication and Oncolysis in p53 Mutant Tumors with ONYX-015, an E1B-55kD Gene-deleted Adenovirus, in Patients with Advanced Head and Neck Cancer: A Phase II Trial
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Endocrinology

PDZK1 and GREB1 Are Estrogen-regulated Genes Expressed in Hormone-responsive Breast Cancer1, 2
Malavika G. Ghosh; Devon A. Thompson; Ronald J. Weigel
View articletitled, <em>PDZK1</em> and <em>GREB1</em> Are Estrogen-regulated Genes Expressed in Hormone-responsive Breast Cancer<sup>1, 2</sup>
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Epidemiology

Risk for Gastric Cancer after Antibiotic Prophylaxis in Patients Undergoing Hip Replacement1
Katja Akre; Lisa B. Signorello; Lars Engstrand; Reinhold Bergström; Sune Larsson; Bengt I. Eriksson; Olof Nyrén
View articletitled, Risk for Gastric Cancer after Antibiotic Prophylaxis in Patients Undergoing Hip Replacement<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Glutathione Peroxidase Codon 198 Polymorphism Variant Increases Lung Cancer Risk1
Duminda Ratnasinghe; Joseph A. Tangrea; Mark R. Andersen; Michael J. Barrett; Jarmo Virtamo; Philip R. Taylor; Demetrius Albanes
View articletitled, Glutathione Peroxidase Codon 198 Polymorphism Variant Increases Lung Cancer Risk<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Experimental Therapeutics

Predicting Tumor Responses to Mitomycin C on the Basis of DT-Diaphorase Activity or Drug Metabolism by Tumor Homogenates: Implications for Enzyme-directed Bioreductive Drug Development1
Roger M. Phillips; Angelika M. Burger; Paul M. Loadman; Claire M. Jarrett; David J. Swaine; Heinz-Herbert Fiebig
View articletitled, Predicting Tumor Responses to Mitomycin C on the Basis of DT-Diaphorase Activity or Drug Metabolism by Tumor Homogenates: Implications for Enzyme-directed Bioreductive Drug Development<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Regression Induced by Intratumor Administration of Adenovirus Vector Expressing CD40 Ligand and Naive Dendritic Cells1
Toshiaki Kikuchi; Naoki Miyazawa; Malcolm A. S. Moore; Ronald G. Crystal
View articletitled, Tumor Regression Induced by Intratumor Administration of Adenovirus Vector Expressing CD40 Ligand and Naive Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Viral Fusogenic Membrane Glycoprotein Expression Causes Syncytia Formation with Bioenergetic Cell Death: Implications for Gene Therapy1
Hajime Higuchi; Steven F. Bronk; Andrew Bateman; Kevin Harrington; Richard G. Vile; Gregory J. Gores
View articletitled, Viral Fusogenic Membrane Glycoprotein Expression Causes Syncytia Formation with Bioenergetic Cell Death: Implications for Gene Therapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Modulation of Mitogen-activated Protein Kinases and Phosphorylation of Bcl-2 by Vinblastine Represent Persistent Forms of Normal Fluctuations at G2-M1
Meiyun Fan; Lihua Du; Albert A. Stone; Kathleen M. Gilbert; Timothy C. Chambers
View articletitled, Modulation of Mitogen-activated Protein Kinases and Phosphorylation of Bcl-2 by Vinblastine Represent Persistent Forms of Normal Fluctuations at G<sub>2</sub>-M<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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The Role of c-jun Kinase in the Apoptotic Response to Nucleoside Analogue-induced DNA Damage1
Deepa Sampath; William Plunkett
View articletitled, The Role of c-jun Kinase in the Apoptotic Response to Nucleoside Analogue-induced DNA Damage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Antitumor Activity of Tumor Necrosis Factor-α Conjugated with Polyvinylpyrrolidone on Solid Tumors in Mice1
Haruhiko Kamada; Yasuo Tsutsumi; Yoko Yamamoto; Tetsunari Kihira; Yoshihisa Kaneda; Yu Mu; Hiroshi Kodaira; Shin-ichi Tsunoda; Shinsaku Nakagawa; Tadanori Mayumi
View articletitled, Antitumor Activity of Tumor Necrosis Factor-α Conjugated with Polyvinylpyrrolidone on Solid Tumors in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Immunology

Cystathionine-β-Synthase cDNA Transfection Alters the Sensitivity and Metabolism of 1-β-d-Arabinofuranosylcytosine in CCRF-CEM Leukemia Cells in Vitro and in Vivo: A Model of Leukemia in Down Syndrome1
Jeffrey W. Taub; Xi Huang; Yubin Ge; Julie A. Dutcher; Mark L. Stout; Ramzi M. Mohammad; Yaddanapudi Ravindranath; Larry H. Matherly
View articletitled, Cystathionine-β-Synthase cDNA Transfection Alters the Sensitivity and Metabolism of 1-β-<span class="small-caps">d</span>-Arabinofuranosylcytosine in CCRF-CEM Leukemia Cells <em>in Vitro</em> and <em>in Vivo</em>: A Model of Leukemia in Down Syndrome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Superior Tumor Protection Induced by a Cellular Vaccine Carrying a Tumor-specific T Helper Epitope by Genetic Exchange of the Class II-associated Invariant Chain Peptide1
Jeroen van Bergen; Marcel Camps; Rienk Offringa; Cornelis J. M. Melief; Ferry Ossendorp; Frits Koning
View articletitled, Superior Tumor Protection Induced by a Cellular Vaccine Carrying a Tumor-specific T Helper Epitope by Genetic Exchange of the Class II-associated Invariant Chain Peptide<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Targeting of Bivalent Anti-ErbB2 Diabody Antibody Fragments to Tumor Cells Is Independent of the Intrinsic Antibody Affinity1
Ulrik B. Nielsen; Gregory P. Adams; Louis M. Weiner; James D. Marks
View articletitled, Targeting of Bivalent Anti-ErbB2 Diabody Antibody Fragments to Tumor Cells Is Independent of the Intrinsic Antibody Affinity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Dead or Alive: Immunogenicity of Human Melanoma Cells When Presented by Dendritic Cells1
Munitta Shaif-Muthana; Catherine McIntyre; Karen Sisley; Ian Rennie; Anna Murray
View articletitled, Dead or Alive: Immunogenicity of Human Melanoma Cells When Presented by Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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A Novel Melanoma Gene (MG50) Encoding the Interleukin 1 Receptor Antagonist and Six Epitopes Recognized by Human Cytolytic T Lymphocytes1
Malcolm S. Mitchell; June Kan-Mitchell; Boris Minev; Carl Edman; Robert J. Deans
View articletitled, A Novel Melanoma Gene (<em>MG50</em>) Encoding the Interleukin 1 Receptor Antagonist and Six Epitopes Recognized by Human Cytolytic T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Adenovirus-Interleukin-12-mediated Tumor Regression in a Murine Hepatocellular Carcinoma Model Is Not Dependent on CD1-restricted Natural Killer T Cells1
Kahlil J. Andrews; Antoni Ribas; Lisa H. Butterfield; Charles M. Vollmer; Fritz C. Eilber; Vivian B. Dissette; Scott D. Nelson; Peter Shintaku; Shahram Mekhoubad; Toshinori Nakayama; Masaru Taniguchi; John A. Glaspy; William H. McBride; James S. Economou
View articletitled, Adenovirus-Interleukin-12-mediated Tumor Regression in a Murine Hepatocellular Carcinoma Model Is Not Dependent on CD1-restricted Natural Killer T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Molecular Biology and Genetics

Differential Effects of Theaflavin Monogallates on Cell Growth, Apoptosis, and Cox-2 Gene Expression in Cancerous versus Normal Cells1
Jiebo Lu; Chi-Tang Ho; Geetha Ghai; Kuang Yu Chen
View articletitled, Differential Effects of Theaflavin Monogallates on Cell Growth, Apoptosis, and <em>Cox-2</em> Gene Expression in Cancerous <em>versus</em> Normal Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Prognostic Value of Genetically Diagnosed Lymph Node Micrometastasis in Non-Small Cell Lung Carcinoma Cases1
Takehisa Hashimoto; Yasuhito Kobayashi; Yuichi Ishikawa; Shigehiro Tsuchiya; Sakae Okumura; Ken Nakagawa; Yoshio Tokuchi; Moriaki Hayashi; Kazunori Nishida; Shin-ichi Hayashi; Jun-ichi Hayashi; Eiju Tsuchiya
View articletitled, Prognostic Value of Genetically Diagnosed Lymph Node Micrometastasis in Non-Small Cell Lung Carcinoma Cases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Two Percent of Finnish Prostate Cancer Patients Have a Germ-line Mutation in the Hormone-binding Domain of the Androgen Receptor Gene1
Nina Mononen; Kirsi Syrjäkoski; Mika Matikainen; Teuvo L. J. Tammela; Johanna Schleutker; Olli-P. Kallioniemi; Jan Trapman; Pasi A. Koivisto
View articletitled, Two Percent of Finnish Prostate Cancer Patients Have a Germ-line Mutation in the Hormone-binding Domain of the Androgen Receptor Gene<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Tumor Biology

Induction of Mammary Differentiation by Mammary-derived Growth Inhibitor-related Gene That Interacts with an ω-3 Fatty Acid on Growth Inhibition of Breast Cancer Cells1
Mingsheng Wang; Yiliang E. Liu; Jian Ni; Banu Aygun; Itzhak D. Goldberg; Y. Eric Shi
View articletitled, Induction of Mammary Differentiation by Mammary-derived Growth Inhibitor-related Gene That Interacts with an ω-3 Fatty Acid on Growth Inhibition of Breast Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Increase of GKLF Messenger RNA and Protein Expression during Progression of Breast Cancer1
K. Wade Foster; Andra R. Frost; Peggy McKie-Bell; Chin-Yu Lin; Jeffrey A. Engler; William E. Grizzle; J. Michael Ruppert
View articletitled, Increase of GKLF Messenger RNA and Protein Expression during Progression of Breast Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Visualization of the Timing of Gene Amplification during Multistep Head and Neck Tumorigenesis1
Hwan J. Roh; Dong M. Shin; Jin S. Lee; Jae Y. Ro; Michael A. Tainsky; Waun K. Hong; Walter N. Hittelman
View articletitled, Visualization of the Timing of Gene Amplification during Multistep Head and Neck Tumorigenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Construction of Evolutionary Tree Models for Renal Cell Carcinoma from Comparative Genomic Hybridization Data1
Feng Jiang; Richard Desper; Christos H. Papadimitriou; Alejandro A. Schäffer; Olli-P. Kallioniemi; Jan Richter; Peter Schraml; Guido Sauter; Michael J. Mihatsch; Holger Moch
View articletitled, Construction of Evolutionary Tree Models for Renal Cell Carcinoma from Comparative Genomic Hybridization Data<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Clonal Selection versus Genetic Instability as the Driving Force in Neoplastic Transformation1
Ming Chow; Harry Rubin
View articletitled, Clonal Selection <em>versus</em> Genetic Instability as the Driving Force in Neoplastic Transformation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Involvement of the Ets-1 Gene in Overexpression of Matrilysin in Human Hepatocellular Carcinoma1
Iwata Ozaki; Toshihiko Mizuta; Gang Zhao; Hiroaki Yotsumoto; Toshiya Hara; Susumu Kajihara; Akitaka Hisatomi; Takahiro Sakai; Kyosuke Yamamoto
View articletitled, Involvement of the Ets-1 Gene in Overexpression of Matrilysin in Human Hepatocellular Carcinoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Treatment of Prostate Cancer by Radioiodine Therapy after Tissue-specific Expression of the Sodium Iodide Symporter1
Christine Spitzweg; Michael K. O’Connor; Elizabeth R. Bergert; Donald J. Tindall; Charles Y. F. Young; John C. Morris
View articletitled, Treatment of Prostate Cancer by Radioiodine Therapy after Tissue-specific Expression of the Sodium Iodide Symporter<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Sp1 Decoy Transfected to Carcinoma Cells Suppresses the Expression of Vascular Endothelial Growth Factor, Transforming Growth Factor β1, and Tissue Factor and Also Cell Growth and Invasion Activities
Hiroaki Ishibashi; Kazunori Nakagawa; Mitsuho Onimaru; Emilio J Castellanous; Yasufumi Kaneda; Yutaka Nakashima; Kanemitsu Shirasuna; Katsuo Sueishi
View articletitled, Sp1 Decoy Transfected to Carcinoma Cells Suppresses the Expression of Vascular Endothelial Growth Factor, Transforming Growth Factor β<sub>1</sub>, and Tissue Factor and Also Cell Growth and Invasion Activities
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Induction of Fas Expression and Augmentation of Fas/Fas Ligand-mediated Apoptosis by the Synthetic Retinoid CD437 in Human Lung Cancer Cells1
Shi-Yong Sun; Ping Yue; Waun Ki Hong; Reuben Lotan
View articletitled, Induction of Fas Expression and Augmentation of Fas/Fas Ligand-mediated Apoptosis by the Synthetic Retinoid CD437 in Human Lung Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a></sup>
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Errata

Errata
View articletitled, Errata

Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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