(ISSN 0099-7013) Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.

Advances in Brief

Celecoxib Inhibits N-Butyl-N-(4-hydroxybutyl)-nitrosamine-induced Urinary Bladder Cancers in Male B6D2F1 Mice and Female Fischer-344 Rats

Clinton J. Grubbs; Ronald A. Lubet; Alane T. Koki; Kathleen M. Leahy; Jaime L. Masferrer; Vernon E. Steele; Gary J. Kelloff; D. L. Hill; Karen Seibert

Abstract

View article

Expression and Function of CYR61, an Angiogenic Factor, in Breast Cancer Cell Lines and Tumor Biopsies 1

Miaw-Sheue Tsai; Ann E. Hornby; Johnathon Lakins; Ruth Lupu

Abstract

View article

Chromosomal Instability in Unirradiated Cells Induced in Vivo by a Bystander Effect of Ionizing Radiation 1

Gwyneth E. Watson; Sally A. Lorimore; Denise A. Macdonald; Eric G. Wright

Abstract

View article

A Variant within the DNA Repair Gene XRCC3 Is Associated with the Development of Melanoma Skin Cancer 1

Samantha L. Winsey; Neil A. Haldar; Howard P. Marsh; Mike Bunce; Sara E. Marshall; Adrian L. Harris; Fenella Wojnarowska; Ken I. Welsh

Abstract

View article

Silibinin Up-Regulates Insulin-like Growth Factor-Binding Protein 3 Expression and Inhibits Proliferation of Androgen-independent Prostate Cancer Cells 1

Xiaolin Zi; Jianchun Zhang; Rajesh Agarwal; Michael Pollak

Abstract

View article

Association between Survival after Treatment for Breast Cancer and Glutathione S-Transferase P1 Ile¹⁰⁵Val Polymorphism 1

Carol Sweeney; Gail Y. McClure; Manal Y. Fares; Angie Stone; Brian F. Coles; Patricia A. Thompson; Soheila Korourian; Laura F. Hutchins; Fred F. Kadlubar; Christine B. Ambrosone

Abstract

View article

Scavenging of Reactive Oxygen Species Leads to Diminished Peritoneal Tumor Recurrence

Marie-Elma E. van Rossen; Wim Sluiter; Fred Bonthuis; Hans Jeekel; Richard L. Marquet; Casper H. J. van Eijck

Abstract

View article

Hyperinducibility of Hypoxia-responsive Genes without p53/p21-dependent Checkpoint in Aggressive Prostate Cancer 1

Konstantin Salnikow; Max Costa; William D. Figg; Mikhail V. Blagosklonny

Abstract

View article

Alcohol Stimulates Estrogen Receptor Signaling in Human Breast Cancer Cell Lines 1

Saijun Fan; Qinghui Meng; Bin Gao; Jason Grossman; Michael Yadegari; Itzhak D. Goldberg; Eliot M. Rosen

Abstract

View article

Somatic Mutations of the CD95 Gene in Hodgkin and Reed-Sternberg Cells 1

Markus Müschen; Daniel Re; Andreas Bräuninger; Jürgen Wolf; Martin-Leo Hansmann; Volker Diehl; Ralf Küppers; Klaus Rajewsky

Abstract

View article

BCL-6 Mutations Are Associated with Immunoglobulin Variable Heavy Chain Mutations in B-Cell Chronic Lymphocytic Leukemia 1

Laura Pasqualucci; Antonino Neri; Luca Baldini; Riccardo Dalla-Favera; Anna Migliazza

Abstract

View article

Biochemistry and Biophysics

Melanoma-targeting Properties of ^99mTechnetium-labeled Cyclic α-Melanocyte-stimulating Hormone Peptide Analogues 1

JianQing Chen; Zhen Cheng; Timothy J. Hoffman; Silvia S. Jurisson; Thomas P. Quinn

Abstract

View article

Down-Regulation of X-linked Inhibitor of Apoptosis Protein Induces Apoptosis in Chemoresistant Human Ovarian Cancer Cells 1

Hiromasa Sasaki; YingLun Sheng; Fumikazu Kotsuji; Benjamin K. Tsang

Abstract

View article

Histone H1 and H3 Dephosphorylation Are Differentially Regulated by Radiation-induced Signal Transduction Pathways 1

Chang Y. Guo; Craig Mizzen; Yu Wang; James M. Larner

Abstract

View article

Interferon-γ Treatment Elevates Caspase-8 Expression and Sensitizes Human Breast Tumor Cells to a Death Receptor-induced Mitochondria-operated Apoptotic Program 1

Carmen Ruiz-Ruiz; Cristina Muñoz-Pinedo; Abelardo López-Rivas

Abstract

View article

Carcinogenesis

The Relationship between Benzo[a]pyrene-induced Mutagenesis and Carcinogenesis in Repair-deficient Cockayne Syndrome Group B Mice 1

Susan W. P. Wijnhoven; Hanneke J. M. Kool; Conny T. M. van Oostrom; Rudolf B. Beems; Leon H. F. Mullenders; Albert A. van Zeeland; Gijsbertus T. J. van der Horst; Harry Vrieling; Harry van Steeg

Abstract

View article

Both (±)syn- and (±)anti-7,12-Dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides Initiate Tumors in Mouse Skin That Possess -CAA- to -CTA- Mutations at Codon 61 of c-H-ras 1

Moon-shong Tang; Suryanarayana V. Vulimiri; Aurora Viaje; James X. Chen; Deepa S. Bilolikar; Rebecca J. Morris; Ronald G. Harvey; Tom J. Slaga; John DiGiovanni

Abstract

View article

Inhibition of Ornithine Decarboxylase (ODC) Decreases Tumor Vascularization and Reverses Spontaneous Tumors in ODC/Ras Transgenic Mice 1

Li Lan; Carol Trempus; Susan K. Gilmour

Abstract

View article

Endocrinology

Estrogenic and Antiproliferative Properties of Glabridin from Licorice in Human Breast Cancer Cells

Snait Tamir; Mark Eizenberg; Dalia Somjen; Naftali Stern; Rayah Shelach; Alvin Kaye; Jacob Vaya

Abstract

View article

Epidemiology

Increased Risk of Prostate Cancer and Benign Prostatic Hyperplasia Associated with a CYP17 Gene Polymorphism with a Gene Dosage Effect 1

Tomonori Habuchi; Zhang Liqing; Takehiro Suzuki; Ryusei Sasaki; Norihiko Tsuchiya; Hiroshi Tachiki; Naotake Shimoda; Shigeru Satoh; Kazunari Sato; Yoshiyuki Kakehi; Toshiyuki Kamoto; Osamu Ogawa; Tetsuro Kato

Abstract

View article

Experimental Therapeutics

Role of the Immune Response during Neuro-attenuated Herpes Simplex Virus-mediated Tumor Destruction in a Murine Intracranial Melanoma Model 1

Cathie G. Miller; Nigel W. Fraser

Abstract

View article

Treatment of Colorectal Liver Metastases by Adenoviral Transfer of Tissue Inhibitor of Metalloproteinases-2 into the Liver Tissue

Karsten Brand; Andrew H. Baker; Alejandra Perez-Cantó; Alexandra Possling; Michael Sacharjat; Martina Geheeb; Wolfgang Arnold

Abstract

View article

The Human Leukemic T-Cell Line, TALL-104, Is Cytotoxic to Human Malignant Brain Tumors and Traffics through Brain Tissue: Implications for Local Adoptive Immunotherapy 1

Carol A. Kruse; Sophie Visonneau; Bette K. Kleinschmidt-DeMasters; Carol J. Gup; German G. Gomez; David B. Paul; Daniela Santoli

Abstract

View article

CM101 Treatment Overrides Tumor-induced Immunoprivilege Leading to Apoptosis 1

F. Michael Yakes; Barbara D. Wamil; Fenglei Sun; He-Ping Yan; Clint E. Carter; Carl G. Hellerqvist

Abstract

View article

Changes in Subcellular Distribution of Topoisomerase IIα Correlate with Etoposide Resistance in Multicell Spheroids and Xenograft Tumors 1

Arusha Oloumi; Susan H. MacPhail; Peter J. Johnston; Judit P. Banáth; Peggy L. Olive

Abstract

View article

Apo2 Ligand/TNF-related Apoptosis-inducing Ligand and Death Receptor 5 Mediate the Apoptotic Signaling Induced by Ionizing Radiation in Leukemic Cells 1

Bendi Gong; Alex Almasan

Abstract

View article

Extensive Contribution of the Multidrug Transporters P-Glycoprotein and Mrp1 to Basal Drug Resistance 1

John D. Allen; Remco F. Brinkhuis; Liesbeth van Deemter; Jan Wijnholds; Alfred H. Schinkel

Abstract

View article

Selective Inhibition of Cyclooxygenase-2 Suppresses Growth and Induces Apoptosis in Human Esophageal Adenocarcinoma Cells 1

Rhonda F. Souza; Kenneth Shewmake; David G. Beer; Byron Cryer; Stuart Jon Spechler

Abstract

View article

Selective Radiosensitization of Drug-resistant MutS Homologue-2 (MSH2) Mismatch Repair-deficient Cells by Halogenated Thymidine (dThd) Analogues: Msh2 Mediates dThd Analogue DNA Levels and the Differential Cytotoxicity and Cell Cycle Effects of the dThd Analogues and 6-Thioguanine 1

Suzanne E. Berry; Thomas W. Davis; Jane E. Schupp; Hwa-Shin Hwang; Niels de Wind; Timothy J. Kinsella

Abstract

View article

Activation of Lytic Epstein-Barr Virus (EBV) Infection by Radiation and Sodium Butyrate in Vitro and in Vivo: A Potential Method for Treating EBV-positive Malignancies 1

Eva M. Westphal; William Blackstock; Wenhai Feng; Bruce Israel; Shannon C. Kenney

Abstract

View article

Immunology

Loss of Interferon-γ Inducibility of TAP1 and LMP2 in a Renal Cell Carcinoma Cell Line 1

Susan E. Dovhey; Nilanjan S. Ghosh; Kenneth L. Wright

Abstract

View article

Pretransplant Tumor Antigen-specific Immunization of Allogeneic Bone Marrow Transplant Donors Enhances Graft-versus-Tumor Activity without Exacerbation of Graft-versus-Host Disease 1

Larry D. Anderson, Jr.; Shahram Mori; Savita Mann; Cherylyn A. Savary; Craig A. Mullen

Abstract

View article

Molecular Biology and Genetics

Hormone-dependent Tumor Regression in Vivo by an Inducible Transcriptional Repressor Directed at the PAX3-FKHR Oncogene 1

Kasirajan Ayyanathan; William J. Fredericks; Carola Berking; Meenhard Herlyn; Christopher Balakrishnan; Edward Gunther; Frank J. Rauscher, III

Abstract

View article

Apoptosis Induced by DNA Damage O 6-Methylguanine Is Bcl-2 and Caspase-9/3 Regulated and Fas/Caspase-8 Independent¹

Kirsten Ochs; Bernd Kaina

Abstract

View article

Ligand-independent Activation of the Androgen Receptor by the Differentiation Agent Butyrate in Human Prostate Cancer Cells 1

Marianne D. Sadar; Martin E. Gleave

Abstract

View article

Tumor Biology

RhoC GTPase, a Novel Transforming Oncogene for Human Mammary Epithelial Cells That Partially Recapitulates the Inflammatory Breast Cancer Phenotype 1

Kenneth L. van Golen; Zhi-Fen Wu; Xiao Tan Qiao; Li Wei Bao; Sofia D. Merajver

Abstract

View article

Tumor Development Is Retarded in Mice Lacking the Gene for Urokinase-Type Plasminogen Activator or Its Inhibitor, Plasminogen Activator Inhibitor-1 1

Linda S. Gutierrez; Alexis Schulman; Teresa Brito-Robinson; Francisco Noria; Victoria A. Ploplis; Francis J. Castellino

Abstract

View article

A New M_r 55,000 Surface Protein Implicated in Melanoma Progression: Association with a Metastatic Phenotype 1

Habib Boukerche; Patrick Baril; Eric Tabone; Frédéric Bérard; Kamel Sanhadji; Brigitte Balme; François Wolf; Henri Perrot; Luc Thomas

Abstract

View article

Reduced Infiltration of Tumor-associated Macrophages in Human Prostate Cancer: Association with Cancer Progression 1

Satoru Shimura; Guang Yang; Shin Ebara; Thomas M. Wheeler; Anna Frolov; Timothy C. Thompson

Abstract

View article

B16 Melanoma Cell Arrest in the Mouse Liver Induces Nitric Oxide Release and Sinusoidal Cytotoxicity: A Natural Hepatic Defense against Metastasis 1

Hui Helen Wang; Alan R. McIntosh; Brian B. Hasinoff; Edward S. Rector; Naeem Ahmed; Dwight M. Nance; F. William Orr

Abstract

View article

Caveolin-1 Levels Are Down-Regulated in Human Colon Tumors, and Ectopic Expression of Caveolin-1 in Colon Carcinoma Cell Lines Reduces Cell Tumorigenicity 1

Florent C. Bender; Marc A. Reymond; Claude Bron; Andrew F. G. Quest

Abstract

View article

Epidermal Growth Factor Receptor Transcriptionally Up-Regulates Vascular Endothelial Growth Factor Expression in Human Glioblastoma Cells via a Pathway Involving Phosphatidylinositol 3′-Kinase and Distinct from That Induced by Hypoxia 1

Amit Maity; Nabendu Pore; Jerry Lee; Don Solomon; Donald M. O’Rourke

Abstract

View article

Inhibition of HER2/neu (erbB-2) and Mitogen-activated Protein Kinases Enhances Tamoxifen Action against HER2-overexpressing, Tamoxifen-resistant Breast Cancer Cells 1

Hirokazu Kurokawa; Anne E. G. Lenferink; Jean F. Simpson; Paul I. Pisacane; Mark X. Sliwkowski; James T. Forbes; Carlos L. Arteaga

Abstract

View article

A Modified p53 Overcomes mdm2-mediated Oncogenic Transformation: A Potential Cancer Therapeutic Agent 1

Jiayuh Lin; Xiaohong Jin; Carmen Page; Vernon K. Sondak; Guihua Jiang; R. Kevin Reynolds

Abstract

View article

Antiserum Raised against an Epitope of the Cholecystokinin B/Gastrin Receptor Inhibits Hepatic Invasion of a Human Colon Tumor 1

Susan A. Watson; Philip A. Clarke; Teresa M. Morris; Martyn E. Caplin

Abstract

View article

Correction

F. Hayes et al., Cancer Res: 60: 2411–2418,2000

Extract

View article

Email alerts

eTOC Alert

Latest
Most Read
Most Cited

Protein phosphatase 1 subunit PPP1R14B stabilizes STMN1 to promote progression and paclitaxel resistance in triple-negative breast cancer

Elevated methionine flux drives pyroptosis evasion in persister cancer cells

PINK1-mediated mitophagy promotes oxidative phosphorylation and redox homeostasis to induce drug-tolerant persister cancer cells

The cytidine deaminase APOBEC3G contributes to cancer mutagenesis and clonal evolution in bladder cancer

Issues

Journal Archive

Table of Contents

Advances in Brief

Biochemistry and Biophysics

Carcinogenesis

Endocrinology

Epidemiology

Experimental Therapeutics

Immunology

Molecular Biology and Genetics

Apoptosis Induced by DNA Damage O6-Methylguanine Is Bcl-2 and Caspase-9/3 Regulated and Fas/Caspase-8 Independent1

Tumor Biology

Correction

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only

Apoptosis Induced by DNA Damage O 6-Methylguanine Is Bcl-2 and Caspase-9/3 Regulated and Fas/Caspase-8 Independent¹