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Volume 60, Issue 16
15 August 2000
Cancer Research Cover Image for Volume 60, Issue 16
All Issues
ISSN 0008-5472
EISSN 1538-7445

Cancer Research

Table of Contents


Advances in Brief

Midkine Promoter-based Adenoviral Vector Gene Delivery for Pediatric Solid Tumors1
Yasuo Adachi; Paul N. Reynolds; Masato Yamamoto; William E. Grizzle; Ken Overturf; Shyuichiro Matsubara; Takashi Muramatsu; David T. Curiel
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Inhibition of Tumor Angiogenesis by a Single-chain Antibody Directed against Vascular Endothelial Growth Factor1
Alessandra Vitaliti; Mariana Wittmer; Rudolf Steiner; Lorenza Wyder; Dario Neri; Roman Klemenz
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Loss of Caspase-8 Expression in Highly Malignant Human Neuroblastoma Cells Correlates with Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis1
Sally Hopkins-Donaldson; Jean-Luc Bodmer; Katia Balmas Bourloud; Christine Beretta Brognara; Jürg Tschopp; Nicole Gross
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Inactivation of Retinoblastoma Protein in Uveal Melanoma by Phosphorylation of Sites in the COOH-Terminal Region1
Milam A. Brantley, Jr.; J. William Harbour
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Absence of Functional Lymphatics within a Murine Sarcoma: A Molecular and Functional Evaluation1
Anders J. Leu; David A. Berk; Athina Lymboussaki; Kari Alitalo; Rakesh K. Jain
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Mutations of the bak Gene in Human Gastric and Colorectal Cancers
Shinya Kondo; Yasuhisa Shinomura; Yoshiji Miyazaki; Tatsuya Kiyohara; Shusaku Tsutsui; Shinji Kitamura; Yutaka Nagasawa; Masanori Nakahara; Shuji Kanayama; Yuji Matsuzawa
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Fenretinide-induced Caspase 3 Activity Involves Increased Protein Stability in a Mechanism Distinct from Reactive Oxygen Species Elevation1
Anna M. DiPietrantonio; Tze-Chen Hsieh; Gloria Juan; Frank Traganos; Zbigniew Darzynkiewicz; Joseph M. Wu
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Cure of Burkitt’s Lymphoma in Severe Combined Immunodeficiency Mice by T Cells, Tetravalent CD3 × CD19 Tandem Diabody, and CD28 Costimulation1
Björn Cochlovius; Sergey M. Kipriyanov; Marike J. J. G. Stassar; Jochen Schuhmacher; Axel Benner; Gerhard Moldenhauer; Melvyn Little
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A Deficiency in DNA Repair and DNA-PKcs Expression in the Radiosensitive BALB/c Mouse1
Ryuichi Okayasu; Katsutoshi Suetomi; Yongjia Yu; Andy Silver; Joel S. Bedford; Roger Cox; Robert L. Ullrich
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Aberrant Methylation of the Estrogen Receptor and E-Cadherin 5′ CpG Islands Increases with Malignant Progression in Human Breast Cancer1
Sharyl J. Nass; James G. Herman; Edward Gabrielson; Philip W. Iversen; Fritz F. Parl; Nancy E. Davidson; Jeremy R. Graff
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Genomic Instability at the BUB1 Locus in Colorectal Cancer, but not in Non-Small Cell Lung Cancer1
Ross G. Jaffrey; Stuart C. Pritchard; Caroline Clark; Graeme I. Murray; James Cassidy; Keith M. Kerr; Marianne C. Nicolson; Howard L. McLeod
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Inactivation of the 14-3-3 σ Gene Is Associated with 5′ CpG Island Hypermethylation in Human Cancers1
Hiromu Suzuki; Fumio Itoh; Minoru Toyota; Takefumi Kikuchi; Hideki Kakiuchi; Kohzoh Imai
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Bcl-2 Overexpression Results in Enhanced Capacitative Calcium Entry and Resistance to SKF-96395-induced Apoptosis1
Scott S. Williams; John N. French; Mark Gilbert; Arun A. Rangaswami; Jan Walleczek; Susan J. Knox
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Effect of Endostatin on Spontaneous Tumorigenesis of Mammary Adenocarcinomas in a Transgenic Mouse Model1
Yumi Yokoyama; Jeffrey E. Green; Vikas P. Sukhatme; S. Ramakrishnan
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Analysis of Adenomatous Polyposis Coli Promoter Hypermethylation in Human Cancer1
Manel Esteller; Andrew Sparks; Minoru Toyota; Montserrat Sanchez-Cespedes; Gabriel Capella; Miguel Angel Peinado; Sara Gonzalez; Gemma Tarafa; David Sidransky; Stephen J. Meltzer; Stephen B. Baylin; James G. Herman
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Diminished DNA Repair and Elevated Mutagenesis in Mammalian Cells Exposed to Hypoxia and Low pH1
Jianling Yuan; Latha Narayanan; Sara Rockwell; Peter M. Glazer
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Biochemistry and Biophysics

Human THP-1 Monocytic Leukemic Cells Induced to Undergo Monocytic Differentiation by Bryostatin 1 Are Refractory to Proteasome Inhibitor-induced Apoptosis1
Catheryne Chen; Hong Lin; Chachata Karanes; George R. Pettit; Ben D. Chen
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Caspase-3 Is Essential for Procaspase-9 Processing and Cisplatin-induced Apoptosis of MCF-7 Breast Cancer Cells1
Céline Blanc; Quinn L. Deveraux; Stanislaw Krajewski; Reiner U. Jänicke; Alan G. Porter; John C. Reed; Rolf Jaggi; Andreas Marti
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Carcinogenesis

A Role for Protein Kinase C-δ in the Regulation of Ornithine Decarboxylase Expression by Oxidative Stress1
Monicah A. Otieno; Thomas W. Kensler
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Targeted Disruption of the Epidermal Growth Factor Receptor Inhibits Development of Papillomas and Carcinomas from Human Papillomavirus-immortalized Keratinocytes
Craig D. Woodworth; Darci Gaiotti; Evan Michael; Laura Hansen; Matthias Nees
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Clinical Investigations

Human Acute Myeloid Leukemia CD34+/CD38− Progenitor Cells Have Decreased Sensitivity to Chemotherapy and Fas-induced Apoptosis, Reduced Immunogenicity, and Impaired Dendritic Cell Transformation Capacities1
Régis T. Costello; Françoise Mallet; Béatrice Gaugler; Danielle Sainty; Christine Arnoulet; Jean-Albert Gastaut; Daniel Olive
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Experimental Therapeutics

The Vitamin D Analogue EB 1089 Prevents Skeletal Metastasis and Prolongs Survival Time in Nude Mice Transplanted with Human Breast Cancer Cells1
Khadija El Abdaimi; Natalie Dion; Vasilios Papavasiliou; Patrice-Etienne Cardinal; Lise Binderup; David Goltzman; Louis-Georges Ste-Marie; Richard Kremer
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Growth Inhibition of Prostate Cancer by an Adenovirus Expressing a Novel Tumor Suppressor Gene, pHyde1
Mitchell S. Steiner; Xiongwen Zhang; Ying Wang; Yi Lu
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Nuclear Factor-κB/IκB Signaling Pathway May Contribute to the Mediation of Paclitaxel-induced Apoptosis in Solid Tumor Cells1
Yi Huang; Korey R. Johnson; James S. Norris; Weimin Fan
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Metabolism and Pharmacokinetics of N1,N11-Diethylnorspermine in a Cebus apella Primate Model1
Raymond J. Bergeron; Ronald L. Merriman; Stephen G. Olson; Jan Wiegand; John Bender; Richard R. Streiff; William R. Weimar
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Hyperthermia Enables Tumor-specific Nanoparticle Delivery: Effect of Particle Size1
Garheng Kong; Rod D. Braun; Mark W. Dewhirst
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Dendritic Cells Containing Apoptotic Melanoma Cells Prime Human CD8+ T Cells for Efficient Tumor Cell Lysis1
Lars Jenne; Jean-François Arrighi; Helmut Jonuleit; Jean-Hilaire Saurat; Conrad Hauser
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Radioiodination via d-Amino Acid Peptide Enhances Cellular Retention and Tumor Xenograft Targeting of an Internalizing Anti-Epidermal Growth Factor Receptor Variant III Monoclonal Antibody1
Catherine F. Foulon; Craig J. Reist; Darell D. Bigner; Michael R. Zalutsky
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2-5A Antisense Telomerase RNA Therapy for Intracranial Malignant Gliomas1
Shigehiko Mukai; Yasuko Kondo; Shoji Koga; Tadashi Komata; Barbara P. Barna; Seiji Kondo
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Sphingosine Enhances Apoptosis of Radiation-resistant Prostate Cancer Cells1
Victor E. Nava; Olivier Cuvillier; Lisa C. Edsall; Kotohiko Kimura; Sheldon Milstien; Edward P. Gelmann; Sarah Spiegel
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Immunology

Targeting and Therapy of Carcinoembryonic Antigen-expressing Tumors in Transgenic Mice with an Antibody-Interleukin 2 Fusion Protein1
Xiaochuan Xu; Patrick Clarke; György Szalai; John E. Shively; Lawrence E. Williams; Yu Shyr; Ergang Shi; F. James Primus
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Tumor Necrosis Factor α and CD40 Ligand Antagonize the Inhibitory Effects of Interleukin 10 on T-Cell Stimulatory Capacity of Dendritic Cells1
Peter Brossart; Anke Zobywalski; Frank Grünebach; Lars Behnke; Gernot Stuhler; Volker L. Reichardt; Lothar Kanz; Wolfram Brugger
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Immunotherapy with Dendritic Cells and Tumor Major Histocompatibility Complex Class I-derived Peptides Requires a High Density of Antigen on Tumor Cells1
Pisana Rawson; Ian F. Hermans; Stephanie P. Huck; Joanna M. Roberts; Hanspeter Pircher; Franca Ronchese
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Naturally Occurring Human Lymphocyte Antigen-A2 Restricted CD8+ T-Cell Response to the Cancer Testis Antigen NY-ESO-1 in Melanoma Patients1
Danila Valmori; Valérie Dutoit; Danielle Liénard; Donata Rimoldi; Mikaël J. Pittet; Patrick Champagne; Kim Ellefsen; Ugur Sahin; Daniel Speiser; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
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Molecular Biology and Genetics

Analysis of Specific Gene Mutations in the Transforming Growth Factor-β Signal Transduction Pathway in Human Ovarian Cancer1
Dan Wang; Tatsuya Kanuma; Hideki Mizunuma; Fumiko Takama; Yoshito Ibuki; Norio Wake; Akira Mogi; Yoshinori Shitara; Seiichi Takenoshita
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The Frequency of Germ-line Mutations in the Breast Cancer Predisposition Genes BRCA1 AND BRCA2 in Familial Prostate Cancer1
Simon A. Gayther; Karen A. F. de Foy; Patricia Harrington; Paul Pharoah; William D. Dunsmuir; Stephen M. Edwards; Cheryl Gillett; Audrey Ardern-Jones; David P. Dearnaley; Douglas F. Easton; Deborah Ford; Robert J. Shearer; Roger S. Kirby; Anna L. Dowe; Joanne Kelly; Michael R. Stratton; Bruce A. J. Ponder; Diana Barnes; Rosalind A. Eeles; The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators
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Comparative Genomic Hybridization Analysis of 38 Breast Cancer Cell Lines: A Basis for Interpreting Complementary DNA Microarray Data1
Farahnaz Forozan; Eija H. Mahlamäki; Outi Monni; Yidong Chen; Robin Veldman; Yuan Jiang; Gerald C. Gooden; Stephen P. Ethier; Anne Kallioniemi; Olli-P. Kallioniemi
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Delineation of the 6p22 Amplification Unit in Urinary Bladder Carcinoma Cell Lines1
Jochen Bruch; Wolfgang A. Schulz; Jürgen Häussler; Ingo Melzner; Silke Brüderlein; Peter Möller; Ralf Kemmerling; Walther Vogel; Horst Hameister
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Transforming Growth Factor-β1 Recruits Histone Deacetylase 1 to a p130 Repressor Complex in Transgenic Mice in Vivo1
Boumediene Bouzahzah; Maofu Fu; Antonio Iavarone; Valentina M. Factor; Snorri S. Thorgeirsson; Richard G. Pestell
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p53 Dependence of Topoisomerase I Recruitment in Vivo1
Yinghui Mao; Shoshiro Okada; Long-Sheng Chang; Mark T. Muller
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Induction of Retinoic Acid Receptor-α by Granulocyte Macrophage Colony-stimulating Factor in Human Myeloid Leukemia Cell Lines1
Takahisa Shimizu; Ken Takeda
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Tumor Biology

Suppression of Human Prostate Cancer Cell Growth By α1-Adrenoceptor Antagonists Doxazosin and Terazosin via Induction of Apoptosis1
Natasha Kyprianou; Cynthia M. Benning
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Tumor Oxygenation in Hormone-Dependent Tumors During Vascular Endothelial Growth Factor Receptor-2 Blockade, Hormone Ablation, and Chemotherapy1
Nils Hansen-Algenstaedt; Brian R. Stoll; Timothy P. Padera; Dennis E. J. G. J. Dolmans; Daniel J. Hicklin; Dai Fukumura; Rakesh K. Jain
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Genetic Reprogramming in Pathways of Colonic Cell Maturation Induced by Short Chain Fatty Acids: Comparison with Trichostatin A, Sulindac, and Curcumin and Implications for Chemoprevention of Colon Cancer1
John M. Mariadason; Georgia A. Corner; Leonard H. Augenlicht
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Insulin-like Growth Factor-I Is an Autocrine Regulator of Chromogranin A Secretion and Growth in Human Neuroendocrine Tumor Cells1
Götz von Wichert; Peter M. Jehle; Andreas Hoeflich; Stefan Koschnick; Henning Dralle; Eckhard Wolf; Bertram Wiedenmann; Bernhard O. Boehm; Guido Adler; Thomas Seufferlein
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Scintigraphic Imaging of the Hypoxia Marker 99mTechnetium-labeled 2,2′-(1,4-Diaminobutane)bis(2-methyl-3-butanone) Dioxime (99mTc-labeled HL-91; Prognox): Noninvasive Detection of Tumor Response to the Antivascular Agent 5,6-Dimethylxanthenone-4-acetic Acid1
Bronwyn G. Siim; Wilda T. Laux; Michael D. Rutland; Barry N. Palmer; William R. Wilson
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Early Deregulation of the p16ink4a-Cyclin D1/Cyclin-dependent Kinase 4-Retinoblastoma Pathway in Cell Proliferation-driven Esophageal Tumorigenesis in Zinc-deficient Rats1
Louise Y. Y. Fong; Vu T. Nguyen; John L. Farber; Kay Huebner; Peter N. Magee
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The N-myc Oncogene in Human Neuroblastoma Cells: Down-Regulation of an Angiogenesis Inhibitor Identified as Activin A1
Stephen Breit; Keith Ashman; Jörg Wilting; Jochen Rössler; Elissavet Hatzi; Theodore Fotsis; Lothar Schweigerer
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Mutational and Nonmutational Activation of p21rasin Rat Colonic Azoxymethane-induced Tumors: Effects on Mitogen-activated Protein Kinase, Cyclooxygenase-2, and Cyclin D11
Marc Bissonnette; Sharad Khare; Friederike C. von Lintig; Ramesh K. Wali; Lan Nguyen; Yingchun Zhang; John Hart; Susan Skarosi; Nissi Varki; Gerry R. Boss; Thomas A. Brasitus
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Acidic pH-induced Elevation in Interleukin 8 Expression by Human Ovarian Carcinoma Cells1
Lei Xu; Isaiah J. Fidler
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Evaluation of Microsatellite Analysis in Urine Sediment for Diagnosis of Bladder Cancer1
Anne Schneider; Stéphane Borgnat; Hervé Lang; Odile Régine; Véronique Lindner; Maysoun Kassem; Christian Saussine; Pierre Oudet; Didier Jacqmin; Marie Pierre Gaub
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The DNA of Annexin V-binding Apoptotic Cells Is Highly Fragmented1
Zsolt Bacsó; Richard B. Everson; James F. Eliason
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Inhibitors of Prostaglandin Synthesis Inhibit Human Prostate Tumor Cell Invasiveness and Reduce the Release of Matrix Metalloproteinases1
Fadwa A. Attiga; Patricia M. Fernandez; Ashani T. Weeraratna; Michael J. Manyak; Steven R. Patierno
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p53 Promotes Selection for Fas-mediated Apoptotic Resistance1
Heather L. Maecker; Constantinos Koumenis; Amato J. Giaccia
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The Effect of Exogenous Prostaglandin Administration on Tumor Size and Yield in Min/+ Mice1
James W. Wilson; Christopher S. Potten
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Deregulated Manganese Superoxide Dismutase Expression and Resistance to Oxidative Injury in p53-deficient Cells1
Giovanni Pani; Barbara Bedogni; Rosanna Anzevino; Renata Colavitti; Bernardetta Palazzotti; Silvia Borrello; Tommaso Galeotti
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Errata

J. F. Novak et al., Cancer Res., 60:3470–3476, 2000.
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Journal Archive


Cancer Research

(1941-Present; volumes 1-current)

Published twice monthly since 1987. From 1941-1986, published monthly.
(ISSN 0008-5472)

The American Journal of Cancer

(1931-1940; volumes 15-40)

Published quarterly in 1931, bimonthly in 1932, and monthly from 1933 to 1940. The journal changed title to Cancer Research in 1941.
(ISSN 0099-7374)

The Journal of Cancer Research

(1916-1930); volumes 1-14)

Published quarterly from 1916 through 1930 (publication was suspended from November 1922 to March 1924). The journal changed title to The American Journal of Cancer in 1931.
(ISSN 0099-7013)

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